Keiyo Takubo Department of Stem Cell Biology, Research Institute National Center for Global Health and Medicine Biography Publications Institution JoVE Articles Keiyo Takubo has not added a biography. If you are Keiyo Takubo and would like to personalize this page please email our Author Liaison for assistance. Publications Characterization of Genetically Modified Mice for Phosphoglycerate Mutase, a Vitally-essential Enzyme in Glycolysis PloS One. 2021 | Pubmed ID: 33914812 P38α Plays Differential Roles in Hematopoietic Stem Cell Activity Dependent on Aging Contexts The Journal of Biological Chemistry. Mar, 2021 | Pubmed ID: 33745970 OGT Regulates Hematopoietic Stem Cell Maintenance Via PINK1-Dependent Mitophagy Cell Reports. Jan, 2021 | Pubmed ID: 33406421 UTX Maintains the Functional Integrity of the Murine Hematopoietic System by Globally Regulating Aging-associated Genes Blood. Feb, 2021 | Pubmed ID: 33174606 Detection of Residual Disease in Chronic Myeloid Leukemia Utilizing Genomic Next Generation Sequencing Reveals Persistence of Differentiated Ph B Cells but Not Bone Marrow Stem/progenitors Leukemia & Lymphoma. 03, 2021 | Pubmed ID: 33106061 Protocol for the Maintenance of Quiescent Murine Hematopoietic Stem Cells STAR Protocols. Sep, 2020 | Pubmed ID: 33111112 Short-chain Fatty Acids Bind to Apoptosis-associated Speck-like Protein to Activate Inflammasome Complex to Prevent Salmonella Infection PLoS Biology. 09, 2020 | Pubmed ID: 32991574 Phosphoglycerate Mutase Cooperates with Chk1 Kinase to Regulate Glycolysis IScience. Jul, 2020 | Pubmed ID: 32634742 Identification and Local Manipulation of Bone Marrow Vasculature During Intravital Imaging Scientific Reports. 04, 2020 | Pubmed ID: 32286470 Discrimination of Dormant and Active Hematopoietic Stem Cells by G Marker Reveals Dormancy Regulation by Cytoplasmic Calcium Cell Reports. 12, 2019 | Pubmed ID: 31851939 Type I Interferon Delivery by IPSC-Derived Myeloid Cells Elicits Antitumor Immunity Via XCR1 Dendritic Cells Cell Reports. 10, 2019 | Pubmed ID: 31577946 Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses Cell. 08, 2019 | Pubmed ID: 31442401 Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo Cell Reports. 07, 2019 | Pubmed ID: 31269436 ATP Turnover and Glucose Dependency in Hematopoietic Stem/progenitor Cells Are Increased by Proliferation and Differentiation Biochemical and Biophysical Research Communications. 06, 2019 | Pubmed ID: 31030941 Potential Involvement of Semaphorin 3A in Maintaining Intervertebral Disc Tissue Homeostasis Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 04, 2019 | Pubmed ID: 30816586 Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. 10, 2018 | Pubmed ID: 29893999 Hematopoietic Insults Damage Bone Marrow Niche by Activating P53 in Vascular Endothelial Cells Experimental Hematology. 07, 2018 | Pubmed ID: 29709619 Gold-nanofève Surface-enhanced Raman Spectroscopy Visualizes Hypotaurine As a Robust Anti-oxidant Consumed in Cancer Survival Nature Communications. 04, 2018 | Pubmed ID: 29674746 Abnormal Hematopoiesis and Hematopoietic Stem Cell Niche [Rinsho Ketsueki] The Japanese Journal of Clinical Hematology. 2017 | Pubmed ID: 28978823 Lysophosphatidic Acid Acyltransferase 3 Tunes the Membrane Status of Germ Cells by Incorporating Docosahexaenoic Acid During Spermatogenesis The Journal of Biological Chemistry. 07, 2017 | Pubmed ID: 28578315 Metabolic Regulation of Hematopoietic and Leukemic Stem/progenitor Cells Under Homeostatic and Stress Conditions International Journal of Hematology. Jul, 2017 | Pubmed ID: 28540498 [Stress Response Mechanism in Hematopoietic Stem Cells.] Clinical Calcium. 2017 | Pubmed ID: 28536320 Acquired Expression of in Mice Induces Dysplastic Myelopoiesis Mimicking Chronic Myelomonocytic Leukemia Blood. 04, 2017 | Pubmed ID: 28209720 Maintenance of the Functional Integrity of Mouse Hematopoiesis by EED and Promotion of Leukemogenesis by EED Haploinsufficiency Scientific Reports. 07, 2016 | Pubmed ID: 27432459 P38α Activates Purine Metabolism to Initiate Hematopoietic Stem/Progenitor Cell Cycling in Response to Stress Cell Stem Cell. 08, 2016 | Pubmed ID: 27345838 Setdb1 Maintains Hematopoietic Stem and Progenitor Cells by Restricting the Ectopic Activation of Nonhematopoietic Genes Blood. 08, 2016 | Pubmed ID: 27301860 Chordoma-derived Cell Line U-CH1-N Recapitulates the Biological Properties of Notochordal Nucleus Pulposus Cells Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 08, 2016 | Pubmed ID: 27248133 Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure Stem Cells (Dayton, Ohio). Apr, 2016 | Pubmed ID: 27095138 Angiopoietin-like Protein 2 Is a Multistep Regulator of Inflammatory Neovascularization in a Murine Model of Age-related Macular Degeneration The Journal of Biological Chemistry. Apr, 2016 | Pubmed ID: 26839315 How Hematopoietic Stem/progenitors and Their Niche Sense and Respond To infectious Stress Experimental Hematology. Feb, 2016 | Pubmed ID: 26646990 Hypoxia Regulates the Hematopoietic Stem Cell Niche Pflugers Archiv : European Journal of Physiology. Jan, 2016 | Pubmed ID: 26490456 CLEC-2 in Megakaryocytes is Critical for Maintenance of Hematopoietic Stem Cells in the Bone Marrow The Journal of Experimental Medicine. Nov, 2015 | Pubmed ID: 26552707 Excessive Reactive Oxygen Species Are Therapeutic Targets for Intervertebral Disc Degeneration Arthritis Research & Therapy. Nov, 2015 | Pubmed ID: 26542776 [Metabolic Regulation of Stem Cells] [Rinsho Ketsueki] The Japanese Journal of Clinical Hematology. Oct, 2015 | Pubmed ID: 26458425 ADAM12 and ADAM17 Are Essential Molecules for Hypoxia-induced Impairment of Neural Vascular Barrier Function Scientific Reports. Aug, 2015 | Pubmed ID: 26242473 Integrative Analysis of the Acquisition of Pluripotency in PGCs Reveals the Mutually Exclusive Roles of Blimp-1 and AKT Signaling Stem Cell Reports. Jul, 2015 | Pubmed ID: 26050930 Bacterial C-di-GMP Affects Hematopoietic Stem/progenitors and Their Niches Through STING Cell Reports. Apr, 2015 | Pubmed ID: 25843711 Regulation of Glycolysis by Pdk Functions As a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells Cell Stem Cell. Jan, 2013 | Pubmed ID: 23290136 Roles of the Hypoxia Response System in Hematopoietic and Leukemic Stem Cells International Journal of Hematology. May, 2012 | Pubmed ID: 22539363 Regulation of the HIF-1alpha Level is Essential for Hematopoietic Stem Cells Cell Stem Cell. Sep, 2010 | Pubmed ID: 20804974 Stem Cell Defects in ATM-deficient Undifferentiated Spermatogonia Through DNA Damage-induced Cell-cycle Arrest Cell Stem Cell. Feb, 2008 | Pubmed ID: 18371438 Premeiotic Germ Cell Defect in Seminiferous Tubules of Atm-null Testis Biochemical and Biophysical Research Communications. Dec, 2006 | Pubmed ID: 17097049 En kultur metode til at opretholde hvilende humane hæmatopoietiske stamceller Hiroshi Kobayashi1, Keiyo Takubo1 1Department of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine JoVE 61938 Bioingegneria
En kultur metode til at opretholde hvilende humane hæmatopoietiske stamceller Hiroshi Kobayashi1, Keiyo Takubo1 1Department of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine JoVE 61938 Bioingegneria