Keizo Takao Japan Science and Technology Agency Core Research for Evolutionary Science and Technology (CREST) Biography Publications Institution JoVE Articles Keizo Takao has not added a biography. If you are Keizo Takao and would like to personalize this page please email our Author Liaison for assistance. Publications Reply to Warren Et Al. and Shay Et Al.: Commonalities Across Species Do Exist and Are Potentially Important Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015 | Pubmed ID: 25540421 Genomic Responses in Mouse Models Greatly Mimic Human Inflammatory Diseases Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015 | Pubmed ID: 25092317 IL1RAPL1 Knockout Mice Show Spine Density Decrease, Learning Deficiency, Hyperactivity and Reduced Anxiety-like Behaviours Scientific Reports. 2014 | Pubmed ID: 25312502 SIRT1 Overexpression Ameliorates a Mouse Model of SOD1-linked Amyotrophic Lateral Sclerosis Via HSF1/HSP70i Chaperone System Molecular Brain. 2014 | Pubmed ID: 25167838 [Immaturity of Brain As an Endophenotype of Neuropsychiatric Disorders] Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2014 | Pubmed ID: 25076776 Mechanisms for Interferon-α-induced Depression and Neural Stem Cell Dysfunction Stem Cell Reports. Jul, 2014 | Pubmed ID: 25068123 Enhanced Stability of Hippocampal Place Representation Caused by Reduced Magnesium Block of NMDA Receptors in the Dentate Gyrus Molecular Brain. 2014 | Pubmed ID: 24893573 Transcriptomic Evidence for Immaturity of the Prefrontal Cortex in Patients with Schizophrenia Molecular Brain. 2014 | Pubmed ID: 24886351 Comprehensive Behavioral Study of MGluR3 Knockout Mice: Implication in Schizophrenia Related Endophenotypes Molecular Brain. 2014 | Pubmed ID: 24758191 Targeted Deletion of the C-terminus of the Mouse Adenomatous Polyposis Coli Tumor Suppressor Results in Neurologic Phenotypes Related to Schizophrenia Molecular Brain. 2014 | Pubmed ID: 24678719 Comprehensive Behavioral Analysis of Cluster of Differentiation 47 Knockout Mice PloS One. 2014 | Pubmed ID: 24586890 Absence of BRINP1 in Mice Causes Increase of Hippocampal Neurogenesis and Behavioral Alterations Relevant to Human Psychiatric Disorders Molecular Brain. 2014 | Pubmed ID: 24528488 Mice Lacking Collapsin Response Mediator Protein 1 Manifest Hyperactivity, Impaired Learning and Memory, and Impaired Prepulse Inhibition Frontiers in Behavioral Neuroscience. 2013 | Pubmed ID: 24409129 PRICKLE1 Interaction with SYNAPSIN I Reveals a Role in Autism Spectrum Disorders PloS One. 2013 | Pubmed ID: 24312498 Point Mutation in Syntaxin-1A Causes Abnormal Vesicle Recycling, Behaviors, and Short Term Plasticity The Journal of Biological Chemistry. Nov, 2013 | Pubmed ID: 24136198 Chronic Overload of SEPT4, a Parkin Substrate That Aggregates in Parkinson's Disease, Causes Behavioral Alterations but Not Neurodegeneration in Mice Molecular Brain. 2013 | Pubmed ID: 23938054 Immature Dentate Gyrus: an Endophenotype of Neuropsychiatric Disorders Neural Plasticity. 2013 | Pubmed ID: 23840971 ENU-mutagenesis Mice with a Non-synonymous Mutation in Grin1 Exhibit Abnormal Anxiety-like Behaviors, Impaired Fear Memory, and Decreased Acoustic Startle Response BMC Research Notes. 2013 | Pubmed ID: 23688147 Synaptosomal-associated Protein 25 Mutation Induces Immaturity of the Dentate Granule Cells of Adult Mice Molecular Brain. 2013 | Pubmed ID: 23497716 Post-natal Treatment by a Blood-brain-barrier Permeable Calpain Inhibitor, SNJ1945 Rescued Defective Function in Lissencephaly Scientific Reports. 2013 | Pubmed ID: 23390575 Deficiency of Schnurri-2, an MHC Enhancer Binding Protein, Induces Mild Chronic Inflammation in the Brain and Confers Molecular, Neuronal, and Behavioral Phenotypes Related to Schizophrenia Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jul, 2013 | Pubmed ID: 23389689 Increased Astrocytic ATP Release Results in Enhanced Excitability of the Hippocampus Glia. Feb, 2013 | Pubmed ID: 23018918 Behavioral Abnormalities Observed in Zfhx2-deficient Mice PloS One. 2012 | Pubmed ID: 23300874 Impaired Synaptic Clustering of Postsynaptic Density Proteins and Altered Signal Transmission in Hippocampal Neurons, and Disrupted Learning Behavior in PDZ1 and PDZ2 Ligand Binding-deficient PSD-95 Knockin Mice Molecular Brain. 2012 | Pubmed ID: 23268962 Comprehensive Behavioral Analysis of Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) Knockout Mice Frontiers in Behavioral Neuroscience. 2012 | Pubmed ID: 23060763 携带全长突变基因 DRPLA 可变大小的扩大 CAG 重复序列的单个副本的 DRPLA 转基因小鼠 Substrains 表现出行为异常和基因表达谱 CAG 重复长度和年龄相关变化。 Neurobiology of Disease. Feb, 2012 | Pubmed ID: 22342974 性腺瘤性息肉病大肠杆菌显性基因敲除小鼠显示 Hypoactivity 和年龄相关工作记忆。 Frontiers in Behavioral Neuroscience. 2011 | Pubmed ID: 22347851 DIP/希望虚增强了突触功能和巴恩斯迷宫中的性能。 Molecular Brain. 2011 | Pubmed ID: 22018352 松弛素-3-缺陷小鼠焦虑相关的行为表明,略有改动。 Frontiers in Behavioral Neuroscience. 2011 | Pubmed ID: 21887138 P301S 突变体的人 Tau 转基因小鼠表现人类 Tauopathies 改变感觉运动门控与痴呆的早期症状。 PloS One. 2011 | Pubmed ID: 21698260 前脑特定一活动 CaMKKα 转基因小鼠海马依赖长期记忆中显示赤字。 Neurobiology of Learning and Memory. Sep, 2011 | Pubmed ID: 21558011 突触在上下文恐惧空调的 E3 连接酶刮板: 刮板合子和超量表达基因突变小鼠的广泛行为震撼。 PloS One. 2011 | Pubmed ID: 21390313 对认知功能和淀粉样 β 代谢的 APP 超量表达小鼠慢性脑灌注不足的影响。 PloS One. 2011 | Pubmed ID: 21305033 灭活的成纤维细胞生长因子结合蛋白 3 会导致焦虑相关行为。 Molecular and Cellular Neurosciences. Jan, 2011 | Pubmed ID: 20851768 15Q 重叠综合征 ; 小鼠模型的探索性活动减少5-羟色胺信号干扰影响。 PloS One. 2010 | Pubmed ID: 21179543 色氨酸 2,3 双加氧酶在成熟颗粒细胞的成年小鼠海马齿状回中的表达式。 Molecular Brain. 2010 | Pubmed ID: 20815922 应激诱发的酪氨酸磷酸化的信号调节蛋白 α 调节行为静止在强迫的游泳测试中。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2010 | Pubmed ID: 20685990 行为的三个 C57BL/6 Substrains 配置的文件。 Frontiers in Behavioral Neuroscience. 2010 | Pubmed ID: 20676234 [作为精神病候选人 Endophenotype 未成熟的海马齿状回]。 Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2010 | Pubmed ID: 20666142 全面的钙钙调素依赖性蛋白激酶四、 基因敲除小鼠的行为分析。 PloS One. 2010 | Pubmed ID: 20209163 SDOP-DB: 鼠标表型分析比较标准化协议数据库。 Bioinformatics (Oxford, England). Apr, 2010 | Pubmed ID: 20194625 Nardilysin 规定了弥漫的成熟和髓鞘化中央和周围神经系统。 Nature Neuroscience. Dec, 2009 | Pubmed ID: 19935654 异常的脑结构和葛兰素史克 3alpha 基因突变小鼠中的行为。 Molecular Brain. 2009 | Pubmed ID: 19925672 KF-1 泛素连接酶: 抑制焦虑。 Frontiers in Neuroscience. May, 2009 | Pubmed ID: 19753093 基础工作内存赤字在 Alpha CaMKII 显性基因敲除小鼠的神经活性变化。 Frontiers in Behavioral Neuroscience. 2009 | Pubmed ID: 19750198 钙蛋白酶抑制 LIS1 表达增加和部分营救 Lissencephaly 小鼠模型体内表型。 Nature Medicine. Oct, 2009 | Pubmed ID: 19734909 宫内的环境基因组互动与儿童的发展 (4): 脑行为 Phenotypying 的基因工程小鼠行为的全面测试电池使用神经精神性疾病的研究。 The Journal of Toxicological Sciences. 2009 | Pubmed ID: 19571483 伴随着异常的神经胶质细胞的相互作用和减少传导速度改变的髓鞘髓鞘蛋白基因表达显示认知功能障碍小鼠。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2009 | Pubmed ID: 19571127 自闭症中看到的人类 15q11 13 重复染色体工程小鼠模型中的异常行为。 Cell. Jun, 2009 | Pubmed ID: 19563756 社会行为异常、 多动,并削弱远程空间内存,增加 D1 介导的多巴胺能神经元一氧化氮合酶基因敲除小鼠的信号。 Molecular Brain. 2009 | Pubmed ID: 19538708 兰尼碱受体的综合行为震撼键入 3 (RyR3) 基因敲除小鼠: 在两个社会互动测试社会接触持续时间减少。 Frontiers in Behavioral Neuroscience. 2009 | Pubmed ID: 19503748 [基因、 行为和精神障碍]。 Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Mar, 2008 | Pubmed ID: 21089339 正常线粒体呼吸功能的远程小鼠空间记忆的至关重要。 Molecular Brain. 2008 | Pubmed ID: 19087269 缺乏 Kf-1 基因的小鼠表现出更多的焦虑-但不是绝望类似行为。 Frontiers in Behavioral Neuroscience. 2008 | Pubmed ID: 18958194 受损的长期记忆力和工作记忆的三大雅基因突变小鼠与 Dtnbp1,精神分裂症易感基因定位在删除操作。 Molecular Brain. 2008 | Pubmed ID: 18945333 钙蛋白酶抑制蛋白基因敲除小鼠的综合行为 Phenotyping。 Molecular Brain. 2008 | Pubmed ID: 18803809 Alpha CaMKII 虚导致未成熟的海马齿状回,精神病新型候选人 Endophenotype。 Molecular Brain. 2008 | Pubmed ID: 18803808 成人前脑的结构和功能完整性连续神经发生的作用。 Nature Neuroscience. Oct, 2008 | Pubmed ID: 18758458 YWHAE,作为精神分裂症可能易感基因编码 14-3-3epsilon 基因的标识。 Human Molecular Genetics. Oct, 2008 | Pubmed ID: 18658164 [调查中精神疾病的基因到行为途径: 方法使用综合行为测试电池上的基因工程小鼠]。 Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2008 | Pubmed ID: 18646600 NMDA 受体亚单位 NR3B 小鼠遗传消融揭示了神经元和 Nonmotoneuronal 的表型。 The European Journal of Neuroscience. Sep, 2007 | Pubmed ID: 17880385 脑-行为 Phenotypying 的基因工程小鼠的神经精神性疾病研究的影响。 Neuroscience Research. Jun, 2007 | Pubmed ID: 17524507 调查中精神失常基因到行为途径: 对转基因小鼠的行为的全面测试电池的使用。 Annals of the New York Academy of Sciences. Nov, 2006 | Pubmed ID: 17185513 针对量子点表面蛋白质与生物素连接酶活细胞中。 Proceedings of the National Academy of Sciences of the United States of America. May, 2005 | Pubmed ID: 15897449 突触 Ca2 + /calmodulin-dependent 蛋白激酶 II 活动生活神经元的可视化。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2005 | Pubmed ID: 15788767 冷受体作为恒温器的离子基础。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2002 | Pubmed ID: 12019319 背景和线索恐惧制约试验小鼠中使用视频分析系统 Hirotaka Shoji1,2, Keizo Takao2,3, Satoko Hattori1,2, Tsuyoshi Miyakawa1,2,3 1Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, 2Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST), 3Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, National Institutes of Natural Sciences JoVE 50871 Comportamento T-迷宫强迫交替和评估工作,并参考在小鼠记忆的左,右的歧视任务 Hirotaka Shoji1,2, Hideo Hagihara1, Keizo Takao3, Satoko Hattori1,2,3, Tsuyoshi Miyakawa1,2,3 1Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, 2Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST), 3Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, National Institutes of Natural Sciences JoVE 3300 Neuroscienze 对小鼠高架十字迷宫 Munekazu Komada1, Keizo Takao1,2, Tsuyoshi Miyakawa2 1Genetic Engineering and Functional Genomics Unit, Frontier Technology Center, Graduate School of Medicine, Kyoto University, 2Institute for Comprehensive Medical Science Division of Systems Medicine, Fujita Health University JoVE 1088 Biologia 光/暗转换测试小鼠 Keizo Takao1, Tsuyoshi Miyakawa1 1Genetic Engineering and Functional Genomics Unit, Horizontal Medical Research Organization, Graduate School of Medicine, Kyoto University JoVE 104 Biologia
背景和线索恐惧制约试验小鼠中使用视频分析系统 Hirotaka Shoji1,2, Keizo Takao2,3, Satoko Hattori1,2, Tsuyoshi Miyakawa1,2,3 1Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, 2Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST), 3Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, National Institutes of Natural Sciences JoVE 50871 Comportamento
T-迷宫强迫交替和评估工作,并参考在小鼠记忆的左,右的歧视任务 Hirotaka Shoji1,2, Hideo Hagihara1, Keizo Takao3, Satoko Hattori1,2,3, Tsuyoshi Miyakawa1,2,3 1Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, 2Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST), 3Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, National Institutes of Natural Sciences JoVE 3300 Neuroscienze
对小鼠高架十字迷宫 Munekazu Komada1, Keizo Takao1,2, Tsuyoshi Miyakawa2 1Genetic Engineering and Functional Genomics Unit, Frontier Technology Center, Graduate School of Medicine, Kyoto University, 2Institute for Comprehensive Medical Science Division of Systems Medicine, Fujita Health University JoVE 1088 Biologia
光/暗转换测试小鼠 Keizo Takao1, Tsuyoshi Miyakawa1 1Genetic Engineering and Functional Genomics Unit, Horizontal Medical Research Organization, Graduate School of Medicine, Kyoto University JoVE 104 Biologia