Kullervo Hynynen Physical Sciences Platform Sunnybrook Research Institute Biography Publications Institution JoVE Articles Kullervo Hynynen has not added a biography. If you are Kullervo Hynynen and would like to personalize this page please email our Author Liaison for assistance. Publications Targeted Nanoparticle for Co-delivery of HER2 SiRNA and a Taxane to Mirror the Standard Treatment of HER2+ Breast Cancer: Efficacy in Breast Tumor and Brain Metastasis Small (Weinheim an Der Bergstrasse, Germany). Jan, 2022 | Pubmed ID: 35083840 Ultrasound Delivery of a TrkA Agonist Confers Neuroprotection to Alzheimer-associated Pathologies Brain : a Journal of Neurology. Dec, 2021 | Pubmed ID: 34919633 Transgene Distribution and Immune Response After Ultrasound Delivery of RAAV9 and PHP.B to the Brain in a Mouse Model of Amyloidosis Molecular Therapy. Methods & Clinical Development. Dec, 2021 | Pubmed ID: 34761053 MR-guided Focused Ultrasound Enhances Delivery of Trastuzumab to Her2-positive Brain Metastases Science Translational Medicine. 10, 2021 | Pubmed ID: 34644145 Comparison of Computer Simulations and Clinical Treatment Results of Magnetic Resonance Guided Focused Ultrasound Surgery (MRgFUS) of Uterine Fibroids Medical Physics. Oct, 2021 | Pubmed ID: 34601729 Sub-millimetre Precision of Drug Delivery in the Brain from Ultrasound-triggered Nanodroplets Journal of Controlled Release : Official Journal of the Controlled Release Society. 10, 2021 | Pubmed ID: 34530050 Focused Ultrasound Neuromodulation International Review of Neurobiology. 2021 | Pubmed ID: 34446247 Intravenous and Non-invasive Drug Delivery to the Mouse Basal ForebrainUsing MRI-guided Focused Ultrasound Bio-protocol. Jun, 2021 | Pubmed ID: 34262999 The Mechanical Potential of Ultrasound on Nervous Tissue The Journal of the Acoustical Society of America. 06, 2021 | Pubmed ID: 34241452 Erratum: "Registration of Human Skull Computed Tomography Data to an Ultrasound Treatment Space Using a Sparse High Frequency Ultrasound Hemispherical Array" [Med. Phys. 43, 5063-5071 (2016)] Medical Physics. Jun, 2021 | Pubmed ID: 34235769 Corrigendum: Perfusion Fixation Methods for Preclinical Biodistribution Studies: a Comparative Assessment Using Automated Image Processing (2021 017001) Methods and Applications in Fluorescence. Jun, 2021 | Pubmed ID: 34110305 Therapeutic Agent Delivery Across the Blood-Brain Barrier Using Focused Ultrasound Annual Review of Biomedical Engineering. 07, 2021 | Pubmed ID: 33752471 MR-guided Focused Ultrasound Liquid Biopsy Enriches Circulating Biomarkers in Patients with Brain Tumors Neuro-oncology. 10, 2021 | Pubmed ID: 33693781 Ultrasound-sensitive Nanodroplets Achieve Targeted Neuromodulation Journal of Controlled Release : Official Journal of the Controlled Release Society. 04, 2021 | Pubmed ID: 33600879 Systemic AAV6-synapsin-GFP Administration Results in Lower Liver Biodistribution, Compared to AAV1&2 and AAV9, with Neuronal Expression Following Ultrasound-mediated Brain Delivery Scientific Reports. 01, 2021 | Pubmed ID: 33479314 Novel Treatment Approaches for Brain Tumour from a Blood-Brain Barrier Perspective Handbook of Experimental Pharmacology. Jan, 2021 | Pubmed ID: 33454856 Neutrophil Recruitment and Leukocyte Response Following Focused Ultrasound and Microbubble Mediated Blood-brain Barrier Treatments Theranostics. 2021 | Pubmed ID: 33408773 Vasculotide Restores the Blood-brain Barrier After Focused Ultrasound-induced Permeability in a Mouse Model of Alzheimer's Disease International Journal of Medical Sciences. 2021 | Pubmed ID: 33390817 Perfusion Fixation Methods for Preclinical Biodistribution Studies: A Comparative Assessment Using Automated Image Processing Methods and Applications in Fluorescence. Jan, 2021 | Pubmed ID: 33316782 Technical Principles and Clinical Workflow of Transcranial MR-Guided Focused Ultrasound Stereotactic and Functional Neurosurgery. 2021 | Pubmed ID: 33302282 MRI-guided Focused Ultrasound Enhances Drug Delivery in Experimental Diffuse Intrinsic Pontine Glioma Journal of Controlled Release : Official Journal of the Controlled Release Society. 02, 2021 | Pubmed ID: 33188825 Applications of Focused Ultrasound in the Brain: from Thermoablation to Drug Delivery Nature Reviews. Neurology. 01, 2021 | Pubmed ID: 33106619 Comparing Rapid Short-pulse to Tone Burst Sonication Sequences for Focused Ultrasound and Microbubble-mediated Blood-brain Barrier Permeability Enhancement Journal of Controlled Release : Official Journal of the Controlled Release Society. 01, 2021 | Pubmed ID: 33022327 Focused Ultrasound and Microbubbles-Mediated Drug Delivery to Brain Tumor Pharmaceutics. Dec, 2020 | Pubmed ID: 33374205 Microbubble Formulation Influences Inflammatory Response to Focused Ultrasound Exposure in the Brain Scientific Reports. 12, 2020 | Pubmed ID: 33299094 Clinically Approved IVIg Delivered to the Hippocampus with Focused Ultrasound Promotes Neurogenesis in a Model of Alzheimer's Disease Proceedings of the National Academy of Sciences of the United States of America. 12, 2020 | Pubmed ID: 33288687 Systematic Examination of Low-intensity Ultrasound Parameters on Human Motor Cortex Excitability and Behavior ELife. 11, 2020 | Pubmed ID: 33236981 Technical and Radiographic Considerations for Magnetic Resonance Imaging-guided Focused Ultrasound Capsulotomy Journal of Neurosurgery. Sep, 2020 | Pubmed ID: 32977311 Novel Fractionated Ultrashort Thermal Exposures with MRI-guided Focused Ultrasound for Treating Tumors with Thermosensitive Drugs Science Advances. Sep, 2020 | Pubmed ID: 32917589 Echo-Focusing in Transcranial Focused Ultrasound Thalamotomy for Essential Tremor: A Feasibility Study Movement Disorders : Official Journal of the Movement Disorder Society. 12, 2020 | Pubmed ID: 32815611 Ultrafast Three-dimensional Microbubble Imaging Predicts Tissue Damage Volume Distributions During Nonthermal Brain Ablation Theranostics. 2020 | Pubmed ID: 32641988 Magnetic Resonance-guided Focused Ultrasound Capsulotomy for Refractory Obsessive Compulsive Disorder and Major Depressive Disorder: Clinical and Imaging Results from Two Phase I Trials Molecular Psychiatry. 09, 2020 | Pubmed ID: 32404942 Simultaneous Intravital Optical and Acoustic Monitoring of Ultrasound-Triggered Nanobubble Generation and Extravasation Nano Letters. 06, 2020 | Pubmed ID: 32374617 Focused Ultrasound As a Novel Strategy for Noninvasive Gene Delivery to Retinal Müller Glia Theranostics. 2020 | Pubmed ID: 32194850 Localized Anesthesia of a Specific Brain Region Using Ultrasound-responsive Barbiturate Nanodroplets Theranostics. 2020 | Pubmed ID: 32194839 Investigating the Effects of Dexamethasone on Blood-brain Barrier Permeability and Inflammatory Response Following Focused Ultrasound and Microbubble Exposure Theranostics. 2020 | Pubmed ID: 32042325 A Noninvasive Ultrasound Resonance Method for Detecting Skull Induced Phase Shifts May Provide a Signal for Adaptive Focusing IEEE Transactions on Bio-medical Engineering. 09, 2020 | Pubmed ID: 31976875 Super-resolution Ultrasound Imaging Ultrasound in Medicine & Biology. 04, 2020 | Pubmed ID: 31973952 Transcranial Photoacoustic Detection of Blood-Brain Barrier Disruption Following Focused Ultrasound-Mediated Nanoparticle Delivery Molecular Imaging and Biology. 04, 2020 | Pubmed ID: 31286352 Strategy to Enhance Transgene Expression in Proximity of Amyloid Plaques in a Mouse Model of Alzheimer's Disease Theranostics. 2019 | Pubmed ID: 31754385 Tractography-based Targeting of the Ventral Intermediate Nucleus: Accuracy and Clinical Utility in MRgFUS Thalamotomy Journal of Neurosurgery. Sep, 2019 | Pubmed ID: 31561221 First-in-human Trial of Blood-brain Barrier Opening in Amyotrophic Lateral Sclerosis Using MR-guided Focused Ultrasound Nature Communications. 09, 2019 | Pubmed ID: 31558719 Glymphatics Visualization After Focused Ultrasound-Induced Blood-Brain Barrier Opening in Humans Annals of Neurology. 12, 2019 | Pubmed ID: 31525269 Safety and Efficacy of Focused Ultrasound Induced Blood-brain Barrier Opening, an Integrative Review of Animal and Human Studies Journal of Controlled Release : Official Journal of the Controlled Release Society. 09, 2019 | Pubmed ID: 31326464 MR-guided Focused Ultrasound Facilitates Sonodynamic Therapy with 5-Aminolevulinic Acid in a Rat Glioma Model Scientific Reports. 07, 2019 | Pubmed ID: 31320671 Resting State Functional Connectivity Changes After MR-guided Focused Ultrasound Mediated Blood-brain Barrier Opening in Patients with Alzheimer's Disease NeuroImage. 10, 2019 | Pubmed ID: 31254646 Acoustic Radiation Force Induced Accumulation and Dynamics of Microbubbles on Compliant Surfaces Physics in Medicine and Biology. 07, 2019 | Pubmed ID: 31082815 Accumulated Thermal Dose in MRI-guided Focused Ultrasound for Essential Tremor: Repeated Sonications with Low Focal Temperatures Journal of Neurosurgery. May, 2019 | Pubmed ID: 31075781 The Relevance of Skull Density Ratio in Selecting Candidates for Transcranial MR-guided Focused Ultrasound Journal of Neurosurgery. May, 2019 | Pubmed ID: 31051458 MRI-Guided Focused Ultrasound for Targeted Delivery of RAAV to the Brain Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30783974 Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study Scientific Reports. 01, 2019 | Pubmed ID: 30674905 Evaluating the Safety Profile of Focused Ultrasound and Microbubble-mediated Treatments to Increase Blood-brain Barrier Permeability Expert Opinion on Drug Delivery. 02, 2019 | Pubmed ID: 30628455 Advances in Acoustic Monitoring and Control of Focused Ultrasound-mediated Increases in Blood-brain Barrier Permeability The British Journal of Radiology. Apr, 2019 | Pubmed ID: 30507302 Enhancing Checkpoint Inhibitor Therapy with Ultrasound Stimulated Microbubbles Ultrasound in Medicine & Biology. 02, 2019 | Pubmed ID: 30447880 Hyperthermia-induced Drug Delivery in Humans Nature Biomedical Engineering. 09, 2018 | Pubmed ID: 31015680 Receiver Array Design for Sonothrombolysis Treatment Monitoring in Deep Vein Thrombosis Physics in Medicine and Biology. Nov, 2018 | Pubmed ID: 30484436 Focused Ultrasound Thalamotomy Location Determines Clinical Benefits in Patients with Essential Tremor Brain : a Journal of Neurology. 12, 2018 | Pubmed ID: 30452554 Microbubble-assisted MRI-guided Focused Ultrasound for Hyperthermia at Reduced Power Levels International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2018 | Pubmed ID: 30295119 Magnetic Resonance-guided Focused Ultrasound Thalamotomy for Treatment of Essential Tremor: A 2-year Outcome Study Movement Disorders : Official Journal of the Movement Disorder Society. 10, 2018 | Pubmed ID: 30288794 Noninvasive Delivery of an α-synuclein Gene Silencing Vector with Magnetic Resonance-guided Focused Ultrasound Movement Disorders : Official Journal of the Movement Disorder Society. 10, 2018 | Pubmed ID: 30264465 Time Course of Focused Ultrasound Effects on β-amyloid Plaque Pathology in the TgCRND8 Mouse Model of Alzheimer's Disease Scientific Reports. 09, 2018 | Pubmed ID: 30232364 Angiogenic Response of Rat Hippocampal Vasculature to Focused Ultrasound-mediated Increases in Blood-brain Barrier Permeability Scientific Reports. 08, 2018 | Pubmed ID: 30111814 Predicting Lesion Size by Accumulated Thermal Dose in MR-guided Focused Ultrasound for Essential Tremor Medical Physics. Oct, 2018 | Pubmed ID: 30098027 Ultrasound and Microbubble-Mediated Blood-Brain Barrier Disruption for Targeted Delivery of Therapeutics to The Brain Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 30051428 Blood-brain Barrier Opening in Alzheimer's Disease Using MR-guided Focused Ultrasound Nature Communications. 07, 2018 | Pubmed ID: 30046032 Microbubble Localization for Three-Dimensional Superresolution Ultrasound Imaging Using Curve Fitting and Deconvolution Methods IEEE Transactions on Bio-medical Engineering. 12, 2018 | Pubmed ID: 29993387 Preliminary Investigation of Focused Ultrasound-Facilitated Drug Delivery for the Treatment of Leptomeningeal Metastases Scientific Reports. 06, 2018 | Pubmed ID: 29899537 Three-dimensional Transcranial Microbubble Imaging for Guiding Volumetric Ultrasound-mediated Blood-brain Barrier Opening Theranostics. 2018 | Pubmed ID: 29896293 An MR-based Quantitative Intraventricular Hemorrhage Porcine Model for MR-guided Focused Ultrasound Thrombolysis Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery. 09, 2018 | Pubmed ID: 29796753 The Reduction in Treatment Efficiency at High Acoustic Powers During MR-guided Transcranial Focused Ultrasound Thalamotomy for Essential Tremor Medical Physics. Jul, 2018 | Pubmed ID: 29758099 Brainstem Blood Brain Barrier Disruption Using Focused Ultrasound: A Demonstration of Feasibility and Enhanced Doxorubicin Delivery Journal of Controlled Release : Official Journal of the Controlled Release Society. 07, 2018 | Pubmed ID: 29753957 Skull Bone Marrow Injury Caused by MR-guided Focused Ultrasound for Cerebral Functional Procedures Journal of Neurosurgery. 05, 2018 | Pubmed ID: 29726769 Reply to Kovacs .: Concerning Acute Inflammatory Response Following Focused Ultrasound and Microbubbles in the Brain Theranostics. 2018 | Pubmed ID: 29722372 Antidepressant Effects of Focused Ultrasound Induced Blood-brain-barrier Opening Behavioural Brain Research. 04, 2018 | Pubmed ID: 29326057 Investigating the Efficacy of a Combination Aβ-targeted Treatment in a Mouse Model of Alzheimer's Disease Brain Research. Jan, 2018 | Pubmed ID: 29066368 Acute Inflammatory Response Following Increased Blood-Brain Barrier Permeability Induced by Focused Ultrasound is Dependent on Microbubble Dose Theranostics. 2017 | Pubmed ID: 29109793 Investigation of the Safety of Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Natural Canine Model of Aging Theranostics. 2017 | Pubmed ID: 28912896 Focused Ultrasound Hyperthermia Mediated Drug Delivery Using Thermosensitive Liposomes and Visualized With Two-Photon Microscopy Theranostics. 2017 | Pubmed ID: 28819458 Megahertz Rate, Volumetric Imaging of Bubble Clouds in Sonothrombolysis Using a Sparse Hemispherical Receiver Array Physics in Medicine and Biology. Sep, 2017 | Pubmed ID: 28786395 A Viscoelastic Model for the Prediction of Transcranial Ultrasound Propagation: Application for the Estimation of Shear Acoustic Properties in the Human Skull Physics in Medicine and Biology. Aug, 2017 | Pubmed ID: 28783716 Design of Patient-specific Focused Ultrasound Arrays for Non-invasive Brain Therapy with Increased Trans-skull Transmission and Steering Range Physics in Medicine and Biology. Aug, 2017 | Pubmed ID: 28665289 Design of a HIFU Array for the Treatment of Deep Venous Thrombosis: a Simulation Study Physics in Medicine and Biology. Jul, 2017 | Pubmed ID: 28486218 A Computerized Tablet System for Evaluating Treatment of Essential Tremor by Magnetic Resonance Guided Focused Ultrasound BMC Neurology. Apr, 2017 | Pubmed ID: 28412948 Focused Ultrasound As a Novel Strategy for Alzheimer Disease Therapeutics Annals of Neurology. 05, 2017 | Pubmed ID: 28395123 Acute Effects of Focused Ultrasound-induced Increases in Blood-brain Barrier Permeability on Rat Microvascular Transcriptome Scientific Reports. 04, 2017 | Pubmed ID: 28374753 Urinary Cytokines/chemokines After Magnetic Resonance-guided High Intensity Focused Ultrasound for Palliative Treatment of Painful Bone Metastases Annals of Palliative Medicine. Jan, 2017 | Pubmed ID: 28209068 To Heat or Not to Heat: Challenges with Clinical Translation of Thermosensitive Liposomes Journal of Controlled Release : Official Journal of the Controlled Release Society. 03, 2017 | Pubmed ID: 28122204 Blood-Brain Barrier Closure Time After Controlled Ultrasound-Induced Opening Is Independent of Opening Volume Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Mar, 2017 | Pubmed ID: 28108988 Magnetic Resonance-Guided High-Intensity-Focused Ultrasound for Palliation of Painful Skeletal Metastases: A Pilot Study Technology in Cancer Research & Treatment. Oct, 2017 | Pubmed ID: 27480322 Opening the Blood-Brain Barrier with MR Imaging-guided Focused Ultrasound: Preclinical Testing on a Trans-Human Skull Porcine Model Radiology. Jan, 2017 | Pubmed ID: 27420647 Noninvasive and Targeted Delivery of Therapeutics to the Brain Using Focused Ultrasound Neuropharmacology. Jul, 2017 | Pubmed ID: 26907805 A Tikhonov Regularization Scheme for Focus Rotations With Focused Ultrasound-Phased Arrays IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 12, 2016 | Pubmed ID: 27913323 A Multi-frequency Sparse Hemispherical Ultrasound Phased Array for Microbubble-mediated Transcranial Therapy and Simultaneous Cavitation Mapping Physics in Medicine and Biology. 12, 2016 | Pubmed ID: 27845920 A Numerical Study on the Oblique Focus in MR-guided Transcranial Focused Ultrasound Physics in Medicine and Biology. Nov, 2016 | Pubmed ID: 27779134 Registration of Human Skull Computed Tomography Data to an Ultrasound Treatment Space Using a Sparse High Frequency Ultrasound Hemispherical Array Medical Physics. Sep, 2016 | Pubmed ID: 27587036 A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor The New England Journal of Medicine. Aug, 2016 | Pubmed ID: 27557301 Image-guided Ultrasound Phased Arrays Are a Disruptive Technology for Non-invasive Therapy Physics in Medicine and Biology. 09, 2016 | Pubmed ID: 27494561 Focused Ultrasound-Induced Neurogenesis Requires an Increase in Blood-Brain Barrier Permeability PloS One. 2016 | Pubmed ID: 27459643 Magnetic Resonance-Guided High-Intensity Focused Ultrasound Hyperthermia for Recurrent Rectal Cancer: MR Thermometry Evaluation and Preclinical Validation International Journal of Radiation Oncology, Biology, Physics. 07, 2016 | Pubmed ID: 27209510 Magnetic Resonance-guided High-intensity Focused Ultrasound Combined with Radiotherapy for Palliation of Head and Neck Cancer-a Pilot Study Journal of Therapeutic Ultrasound. 2016 | Pubmed ID: 27042308 Early Treatment of HER2-amplified Brain Tumors with Targeted NK-92 Cells and Focused Ultrasound Improves Survival Neuro-oncology. 07, 2016 | Pubmed ID: 26819443 A Review of Ablative Techniques in the Treatment of Breast Fibroadenomata Journal of Therapeutic Ultrasound. 2016 | Pubmed ID: 26788322 Comparison of Analytical and Numerical Approaches for CT-based Aberration Correction in Transcranial Passive Acoustic Imaging Physics in Medicine and Biology. Jan, 2016 | Pubmed ID: 26605827 Microbubble-Assisted Ultrasound for Drug Delivery in the Brain and Central Nervous System Advances in Experimental Medicine and Biology. 2016 | Pubmed ID: 26486344 Combined Therapeutic and Monitoring Ultrasonic Catheter For Cardiac Ablation Therapies Ultrasound in Medicine & Biology. Jan, 2016 | Pubmed ID: 26431798 Frequency Considerations for Deep Ablation with High-intensity Focused Ultrasound: A Simulation Study Medical Physics. Aug, 2015 | Pubmed ID: 26233216 Experimental Demonstration of Passive Acoustic Imaging in the Human Skull Cavity Using CT-based Aberration Corrections Medical Physics. Jul, 2015 | Pubmed ID: 26133635 Quantitative MRI in a Non-surgical Model of Cervical Spinal Cord Injury NMR in Biomedicine. Aug, 2015 | Pubmed ID: 26053102 Focused Ultrasound-mediated Drug Delivery Through the Blood-brain Barrier Expert Review of Neurotherapeutics. May, 2015 | Pubmed ID: 25936845 Emerging Non-cancer Applications of Therapeutic Ultrasound International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. May, 2015 | Pubmed ID: 25792225 Gene Delivery to the Spinal Cord Using MRI-guided Focused Ultrasound Gene Therapy. Jul, 2015 | Pubmed ID: 25781651 A Novel, Flat, Electronically-steered Phased Array Transducer for Tissue Ablation: Preliminary Results Physics in Medicine and Biology. Mar, 2015 | Pubmed ID: 25683789 Hyperthermia-mediated Doxorubicin Release from Thermosensitive Liposomes Using MR-HIFU: Therapeutic Effect in Rabbit Vx2 Tumours International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Mar, 2015 | Pubmed ID: 25582131 Microbubbles and Blood-brain Barrier Opening: a Numerical Study on Acoustic Emissions and Wall Stress Predictions IEEE Transactions on Bio-medical Engineering. May, 2015 | Pubmed ID: 25546853 Modeling Localized Delivery of Doxorubicin to the Brain Following Focused Ultrasound Enhanced Blood-brain Barrier Permeability Physics in Medicine and Biology. Oct, 2014 | Pubmed ID: 25230100 Alzheimer Disease in a Mouse Model: MR Imaging-guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-brain Barrier and Improves Pathologic Abnormalities and Behavior Radiology. Dec, 2014 | Pubmed ID: 25222068 Analysis of Focused Ultrasound-induced Blood-brain Barrier Permeability in a Mouse Model of Alzheimer's Disease Using Two-photon Microscopy Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2014 | Pubmed ID: 25107692 High-intensity Focused Ultrasound Sonothrombolysis: the Use of Perfluorocarbon Droplets to Achieve Clot Lysis at Reduced Acoustic Power Ultrasound in Medicine & Biology. Sep, 2014 | Pubmed ID: 25023095 Simulation Study of the Effects of Near- and Far-field Heating During Focused Ultrasound Uterine Fibroid Ablation Using an Electronically Focused Phased Array: A Theoretical Analysis of Patient Safety Medical Physics. Jul, 2014 | Pubmed ID: 24989412 A Non-surgical Model of Cervical Spinal Cord Injury Induced with Focused Ultrasound and Microbubbles Journal of Neuroscience Methods. Sep, 2014 | Pubmed ID: 24970578 Intracranial Applications of Magnetic Resonance-guided Focused Ultrasound Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Jul, 2014 | Pubmed ID: 24850310 Three-dimensional Transcranial Ultrasound Imaging of Microbubble Clouds Using a Sparse Hemispherical Array IEEE Transactions on Bio-medical Engineering. Apr, 2014 | Pubmed ID: 24658252 Drug Delivery Across the Blood-brain Barrier Using Focused Ultrasound Expert Opinion on Drug Delivery. May, 2014 | Pubmed ID: 24650132 Stimulation of Hippocampal Neurogenesis by Transcranial Focused Ultrasound and Microbubbles in Adult Mice Brain Stimulation. Mar-Apr, 2014 | Pubmed ID: 24629831 Numerical Simulations of Clinical Focused Ultrasound Functional Neurosurgery Physics in Medicine and Biology. Apr, 2014 | Pubmed ID: 24619067 Focused Ultrasound Delivery of Raman Nanoparticles Across the Blood-brain Barrier: Potential for Targeting Experimental Brain Tumors Nanomedicine : Nanotechnology, Biology, and Medicine. Jul, 2014 | Pubmed ID: 24374363 The Evaluation of Steerable Ultrasonic Catheters for Minimally Invasive MRI-guided Cardiac Ablation Magnetic Resonance in Medicine. Aug, 2014 | Pubmed ID: 24114767 The Application of Sparse Arrays in High Frequency Transcranial Focused Ultrasound Therapy: a Simulation Study Medical Physics. Dec, 2013 | Pubmed ID: 24320540 A Super-resolution Ultrasound Method for Brain Vascular Mapping Medical Physics. Nov, 2013 | Pubmed ID: 24320408 Cavitation-based Third Ventriculostomy Using MRI-guided Focused Ultrasound Journal of Neurosurgery. Dec, 2013 | Pubmed ID: 24074494 Drug Delivery to the Brain by Focused Ultrasound Induced Blood-brain Barrier Disruption: Quantitative Evaluation of Enhanced Permeability of Cerebral Vasculature Using Two-photon Microscopy Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2013 | Pubmed ID: 24008151 Transcranial Passive Acoustic Mapping with Hemispherical Sparse Arrays Using CT-based Skull-specific Aberration Corrections: a Simulation Study Physics in Medicine and Biology. Jul, 2013 | Pubmed ID: 23807573 Creating Brain Lesions with Low-intensity Focused Ultrasound with Microbubbles: a Rat Study at Half a Megahertz Ultrasound in Medicine & Biology. Aug, 2013 | Pubmed ID: 23743099 Amyloid-β Plaque Reduction, Endogenous Antibody Delivery and Glial Activation by Brain-targeted, Transcranial Focused Ultrasound Experimental Neurology. May, 2013 | Pubmed ID: 23707300 Enhancing Drug Delivery for Boron Neutron Capture Therapy of Brain Tumors with Focused Ultrasound Neuro-oncology. Sep, 2013 | Pubmed ID: 23640533 Noninvasive and Targeted Drug Delivery to the Brain Using Focused Ultrasound ACS Chemical Neuroscience. Apr, 2013 | Pubmed ID: 23379618 Focused Ultrasound Delivers Targeted Immune Cells to Metastatic Brain Tumors Cancer Research. Mar, 2013 | Pubmed ID: 23302230 Contrast-enhanced Transcranial Two-dimensional Ultrasound Imaging Using Shear-mode Conversion at Low Frequency Ultrasound in Medicine & Biology. Feb, 2013 | Pubmed ID: 23245822 Antitumor Effects of Combining Docetaxel (taxotere) with the Antivascular Action of Ultrasound Stimulated Microbubbles PloS One. 2012 | Pubmed ID: 23284980 Enhanced Drug Delivery in Rabbit VX2 Tumours Using Thermosensitive Liposomes and MRI-controlled Focused Ultrasound Hyperthermia International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2012 | Pubmed ID: 23153219 Focused Ultrasound for Targeted Delivery of SiRNA and Efficient Knockdown of Htt Expression Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2012 | Pubmed ID: 22921802 High-intensity Focused Ultrasound (HIFU) for Dissolution of Clots in a Rabbit Model of Embolic Stroke PloS One. 2012 | Pubmed ID: 22870315 Targeted Delivery of Self-complementary Adeno-associated Virus Serotype 9 to the Brain, Using Magnetic Resonance Imaging-guided Focused Ultrasound Human Gene Therapy. Nov, 2012 | Pubmed ID: 22838844 Improved Anti-tumor Effect of Liposomal Doxorubicin After Targeted Blood-brain Barrier Disruption by MRI-guided Focused Ultrasound in Rat Glioma Ultrasound in Medicine & Biology. Oct, 2012 | Pubmed ID: 22818878 The Design of a Focused Ultrasound Transducer Array for the Treatment of Stroke: a Simulation Study Physics in Medicine and Biology. Aug, 2012 | Pubmed ID: 22800986 Ultrasound Enhanced Drug Delivery to the Brain and Central Nervous System International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2012 | Pubmed ID: 22621739 Overview of Therapeutic Ultrasound Applications and Safety Considerations Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Apr, 2012 | Pubmed ID: 22441920 Hyperthermia in Bone Generated with MR Imaging-controlled Focused Ultrasound: Control Strategies and Drug Delivery Radiology. Apr, 2012 | Pubmed ID: 22438444 In Vitro and In Vivo High-Intensity Focused Ultrasound Thrombolysis Investigative Radiology. Feb, 2012 | Pubmed ID: 22373533 Enhanced Delivery of Gold Nanoparticles with Therapeutic Potential into the Brain Using MRI-guided Focused Ultrasound Nanomedicine : Nanotechnology, Biology, and Medicine. Feb, 2012 | Pubmed ID: 22349099 Hyperthermia in Bone Generated with MR Imaging-controlled Focused Ultrasound: Control Strategies and Drug Delivery Radiology. Feb, 2012 | Pubmed ID: 22344400 Blood-Brain Barrier: Real-time Feedback-controlled Focused Ultrasound Disruption by Using an Acoustic Emissions-based Controller Radiology. Feb, 2012 | Pubmed ID: 22332065 Focused Ultrasound Disruption of the Blood-brain Barrier: a New Frontier for Therapeutic Delivery in Molecular Neurooncology Neurosurgical Focus. Jan, 2012 | Pubmed ID: 22208896 Pulsed Focused Ultrasound-induced Displacements in Confined in Vitro Blood Clots IEEE Transactions on Bio-medical Engineering. Mar, 2012 | Pubmed ID: 22194235 Investigation of Standing-wave Formation in a Human Skull for a Clinical Prototype of a Large-aperture, Transcranial MR-guided Focused Ultrasound (MRgFUS) Phased Array: an Experimental and Simulation Study IEEE Transactions on Bio-medical Engineering. Feb, 2012 | Pubmed ID: 22049360 Ultrafast 1D MR Thermometry Using Phase or Frequency Mapping Magma (New York, N.Y.). Feb, 2012 | Pubmed ID: 21800192 MRIgHIFU: a Tool for Image-guided Therapeutics Journal of Magnetic Resonance Imaging : JMRI. Sep, 2011 | Pubmed ID: 22896850 Driving Circuitry for Focused Ultrasound Noninvasive Surgery and Drug Delivery Applications Sensors (Basel, Switzerland). 2011 | Pubmed ID: 22346589 Targeted Delivery of Neural Stem Cells to the Brain Using MRI-guided Focused Ultrasound to Disrupt the Blood-brain Barrier PloS One. 2011 | Pubmed ID: 22114718 Ultrasound Insertion Loss of Rat Parietal Bone Appears to Be Proportional to Animal Mass at Submegahertz Frequencies Ultrasound in Medicine & Biology. Nov, 2011 | Pubmed ID: 21925788 The Utility of Sparse 2D Fully Electronically Steerable Focused Ultrasound Phased Arrays for Thermal Surgery: a Simulation Study Physics in Medicine and Biology. Aug, 2011 | Pubmed ID: 21772081 Simulations and Measurements of Transcranial Low-frequency Ultrasound Therapy: Skull-base Heating and Effective Area of Treatment Physics in Medicine and Biology. Aug, 2011 | Pubmed ID: 21734333 Localized Harmonic Motion Imaging for Focused Ultrasound Surgery Targeting Ultrasound in Medicine & Biology. Aug, 2011 | Pubmed ID: 21683514 Two-photon Fluorescence Microscopy Study of Cerebrovascular Dynamics in Ultrasound-induced Blood-brain Barrier Opening Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Sep, 2011 | Pubmed ID: 21505473 Focused Ultrasound Surgery in Oncology: Overview and Principles Radiology. Apr, 2011 | Pubmed ID: 21436096 Focused-ultrasound Disruption of the Blood-brain Barrier Using Closely-timed Short Pulses: Influence of Sonication Parameters and Injection Rate Ultrasound in Medicine & Biology. Apr, 2011 | Pubmed ID: 21376455 MR-guided Focused Ultrasound for Brain Ablation and Blood-brain Barrier Disruption Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21279624 Localised Drug Release Using MRI-controlled Focused Ultrasound Hyperthermia International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2011 | Pubmed ID: 21158487 Multi-frequency Characterization of the Speed of Sound and Attenuation Coefficient for Longitudinal Transmission of Freshly Excised Human Skulls Physics in Medicine and Biology. Jan, 2011 | Pubmed ID: 21149950 Hyperthermia Combined with Radiation for the Treatment of Locally Advanced Prostate Cancer: Long-term Results from Dana-Farber Cancer Institute Study 94-153 Cancer. Feb, 2011 | Pubmed ID: 20886629 Focused Ultrasound-mediated Bbb Disruption is Associated with an Increase in Activation of AKT: Experimental Study in Rats BMC Neurology. 2010 | Pubmed ID: 21078165 The Impact of Standing Wave Effects on Transcranial Focused Ultrasound Disruption of the Blood-brain Barrier in a Rat Model Physics in Medicine and Biology. Sep, 2010 | Pubmed ID: 20720286 In Vitro Characterization of Perfluorocarbon Droplets for Focused Ultrasound Therapy Physics in Medicine and Biology. Sep, 2010 | Pubmed ID: 20693614 Influence of Exposure Time and Pressure Amplitude on Blood-brain-barrier Opening Using Transcranial Ultrasound Exposures ACS Chemical Neuroscience. May, 2010 | Pubmed ID: 20563295 A PVDF Receiver for Ultrasound Monitoring of Transcranial Focused Ultrasound Therapy IEEE Transactions on Bio-medical Engineering. Sep, 2010 | Pubmed ID: 20515709 Antibodies Targeted to the Brain with Image-guided Focused Ultrasound Reduces Amyloid-beta Plaque Load in the TgCRND8 Mouse Model of Alzheimer's Disease PloS One. 2010 | Pubmed ID: 20485502 Contrast Agent Kinetics in the Rabbit Brain During Exposure to Therapeutic Ultrasound Ultrasound in Medicine & Biology. Jun, 2010 | Pubmed ID: 20447757 Ultrasound-induced Activation of Wnt Signaling in Human MG-63 Osteoblastic Cells Bone. Aug, 2010 | Pubmed ID: 20435172 Temperature Change Near Microbubbles Within a Capillary Network During Focused Ultrasound Physics in Medicine and Biology. Mar, 2010 | Pubmed ID: 20164536 Hyperthermia Classic Commentary: 'A Scanned, Focused, Multiple Transducer Ultrasonic System for Localised Hyperthermia Treatments', by K. Hynynen, R. Roemer, D. Anhalt, Et Al., International Journal of Hyperthermia 1987;3:21-35 International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Feb, 2010 | Pubmed ID: 20100047 Transcranial Magnetic Resonance Imaging- Guided Focused Ultrasound Surgery of Brain Tumors: Initial Findings in 3 Patients Neurosurgery. Feb, 2010 | Pubmed ID: 20087132 Local Harmonic Motion Monitoring of Focused Ultrasound Surgery--a Simulation Model IEEE Transactions on Bio-medical Engineering. Jan, 2010 | Pubmed ID: 19822463 MRI-guided Focused Ultrasound Treatments Ultrasonics. Feb, 2010 | Pubmed ID: 19818981 Feasibility of Using Lateral Mode Coupling Method for a Large Scale Ultrasound Phased Array for Noninvasive Transcranial Therapy IEEE Transactions on Bio-medical Engineering. Jan, 2010 | Pubmed ID: 19695987 Focused Ultrasound Effects on Nerve Action Potential in Vitro Ultrasound in Medicine & Biology. Oct, 2009 | Pubmed ID: 19647923 MR Acoustic Radiation Force Imaging: in Vivo Comparison to Ultrasound Motion Tracking Medical Physics. Jun, 2009 | Pubmed ID: 19610290 An MRI-compatible System for Focused Ultrasound Experiments in Small Animal Models Medical Physics. May, 2009 | Pubmed ID: 19544806 Focused Ultrasound Treatment of VX2 Tumors Controlled by Local Harmonic Motion Physics in Medicine and Biology. Jun, 2009 | Pubmed ID: 19436103 New Design for an Endoesophageal Sector- Based Array for the Treatment of Atrial Fibrillation: a Parametric Simulation Study IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Mar, 2009 | Pubmed ID: 19411218 Lateral Mode Coupling to Reduce the Electrical Impedance of Small Elements Required for High Power Ultrasound Therapy Phased Arrays IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Mar, 2009 | Pubmed ID: 19411214 MRI-based Thermal Dosimetry and Diffusion-weighted Imaging of MRI-guided Focused Ultrasound Thermal Ablation of Uterine Fibroids Journal of Magnetic Resonance Imaging : JMRI. Feb, 2009 | Pubmed ID: 19161196 Transcranial Shear-mode Ultrasound: Assessment of Imaging Performance and Excitation Techniques IEEE Transactions on Medical Imaging. May, 2009 | Pubmed ID: 19150789 Macromolecular Delivery Across the Blood-brain Barrier Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19085123 In Vivo Monitoring of Focused Ultrasound Surgery Using Local Harmonic Motion Ultrasound in Medicine & Biology. Jan, 2009 | Pubmed ID: 18805626 Genome-wide Microarray Analysis of MG-63 Osteoblastic Cells Exposed to Ultrasound Biorheology. 2008 | Pubmed ID: 18836235 Evaluation of Referenceless Thermometry in MRI-guided Focused Ultrasound Surgery of Uterine Fibroids Journal of Magnetic Resonance Imaging : JMRI. Oct, 2008 | Pubmed ID: 18821603 Simulations of Lesion Detection Using a Combined Phased Array LHMI-technique Ultrasonics. Nov, 2008 | Pubmed ID: 18778843 Uterine Leiomyomas: MR Imaging-guided Focused Ultrasound Surgery--imaging Predictors of Success Radiology. Oct, 2008 | Pubmed ID: 18695211 Progress and Problems in the Application of Focused Ultrasound for Blood-brain Barrier Disruption Ultrasonics. Aug, 2008 | Pubmed ID: 18511095 Ultrasound for Drug and Gene Delivery to the Brain Advanced Drug Delivery Reviews. Jun, 2008 | Pubmed ID: 18486271 Ultrasound Enhanced Delivery of Molecular Imaging and Therapeutic Agents in Alzheimer's Disease Mouse Models PloS One. 2008 | Pubmed ID: 18478109 Effect of Focused Ultrasound Applied with an Ultrasound Contrast Agent on the Tight Junctional Integrity of the Brain Microvascular Endothelium Ultrasound in Medicine & Biology. Jul, 2008 | Pubmed ID: 18378064 Fetal Thermal Effects of Diagnostic Ultrasound Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Apr, 2008 | Pubmed ID: 18359908 Effects of Acoustic Parameters and Ultrasound Contrast Agent Dose on Focused-ultrasound Induced Blood-brain Barrier Disruption Ultrasound in Medicine & Biology. Jun, 2008 | Pubmed ID: 18294757 Blood-brain Barrier Disruption Induced by Focused Ultrasound and Circulating Preformed Microbubbles Appears to Be Characterized by the Mechanical Index Ultrasound in Medicine & Biology. May, 2008 | Pubmed ID: 18207311 Progress in Multimodality Imaging: Truly Simultaneous Ultrasound and Magnetic Resonance Imaging IEEE Transactions on Medical Imaging. Dec, 2007 | Pubmed ID: 18092742 Treatment of Near-skull Brain Tissue with a Focused Device Using Shear-mode Conversion: a Numerical Study Physics in Medicine and Biology. Dec, 2007 | Pubmed ID: 18065841 Temperature Mapping Considerations in the Breast with Line Scan Echo Planar Spectroscopic Imaging Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Dec, 2007 | Pubmed ID: 18046702 A Computer-controlled Ultrasound Pulser-receiver System for Transskull Fluid Detection Using a Shear Wave Transmission Technique IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Sep, 2007 | Pubmed ID: 17941383 The Effects of Desiccation on Skull Bone Sound Speed in Porcine Models IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Aug, 2007 | Pubmed ID: 17703676 Circumferential Lesion Formation Around the Pulmonary Veins in the Left Atrium with Focused Ultrasound Using a 2D-array Endoesophageal Device: a Numerical Study Physics in Medicine and Biology. Aug, 2007 | Pubmed ID: 17671344 Cavitation Threshold of Microbubbles in Gel Tunnels by Focused Ultrasound Ultrasound in Medicine & Biology. Oct, 2007 | Pubmed ID: 17590501 Clinical Applications of Focused Ultrasound-the Brain International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Mar, 2007 | Pubmed ID: 17578343 Key Factors That Affect Sonoporation Efficiency in in Vitro Settings: the Importance of Standing Wave in Sonoporation Biochemical and Biophysical Research Communications. Aug, 2007 | Pubmed ID: 17568561 Chemotherapy Delivery Issues in Central Nervous System Malignancy: a Reality Check Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2007 | Pubmed ID: 17538176 Uterine Leiomyomas: MR Imaging-guided Focused Ultrasound Surgery--results of Different Treatment Protocols Radiology. Jun, 2007 | Pubmed ID: 17446521 A Novel Phase Assignment Protocol and Driving System for a High-density Focused Ultrasound Array IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Apr, 2007 | Pubmed ID: 17441588 Targeted Delivery of Doxorubicin to the Rat Brain at Therapeutic Levels Using MRI-guided Focused Ultrasound International Journal of Cancer. Journal International Du Cancer. Aug, 2007 | Pubmed ID: 17437269 Use of Ultrasound Pulses Combined with Definity for Targeted Blood-brain Barrier Disruption: a Feasibility Study Ultrasound in Medicine & Biology. Apr, 2007 | Pubmed ID: 17337109 Modular Design for in Vivo Optical Imaging and Ultrasound Treatment in the Murine Brain IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Feb, 2007 | Pubmed ID: 17328340 Activation of Bak in Ultrasound-induced, JNK- and P38-independent Apoptosis and Its Inhibition by Bcl-2 Biochemical and Biophysical Research Communications. Feb, 2007 | Pubmed ID: 17188240 Focused Ultrasound for Blood-brain Disruption and Delivery of Therapeutic Molecules into the Brain Expert Opinion on Drug Delivery. Jan, 2007 | Pubmed ID: 17184160 Multiphoton Imaging of Ultrasound/Optison Mediated Cerebrovascular Effects in Vivo Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2007 | Pubmed ID: 16685254 Induction of Apoptosis in Vivo in the Rabbit Brain with Focused Ultrasound and Optison Ultrasound in Medicine & Biology. Dec, 2006 | Pubmed ID: 17169704 Quality Assurance and System Stability of a Clinical MRI-guided Focused Ultrasound System: Four-year Experience Medical Physics. Nov, 2006 | Pubmed ID: 17153409 Investigation of Optimal Method for Inducing Harmonic Motion in Tissue Using a Linear Ultrasound Phased Array--a Simulation Study Ultrasonic Imaging. Apr, 2006 | Pubmed ID: 17094690 Image-guided Neurosurgery at Brigham and Women's Hospital IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. Sep-Oct, 2006 | Pubmed ID: 17020201 Microbubble Contrast Agent with Focused Ultrasound to Create Brain Lesions at Low Power Levels: MR Imaging and Histologic Study in Rabbits Radiology. Oct, 2006 | Pubmed ID: 16990673 Brain Arterioles Show More Active Vesicular Transport of Blood-borne Tracer Molecules Than Capillaries and Venules After Focused Ultrasound-evoked Opening of the Blood-brain Barrier Ultrasound in Medicine & Biology. Sep, 2006 | Pubmed ID: 16965980 Focal Disruption of the Blood-brain Barrier Due to 260-kHz Ultrasound Bursts: a Method for Molecular Imaging and Targeted Drug Delivery Journal of Neurosurgery. Sep, 2006 | Pubmed ID: 16961141 Simulations of Localized Harmonic Motions on a Blood Vessel Wall Induced by an Acoustic Radiation Force Used in Ultrasound Elastography Physics in Medicine and Biology. Sep, 2006 | Pubmed ID: 16953044 Ultrasound Stimulates Proteoglycan Synthesis in Bovine Primary Chondrocytes Biorheology. 2006 | Pubmed ID: 16912400 Noninvasive Localized Delivery of Herceptin to the Mouse Brain by MRI-guided Focused Ultrasound-induced Blood-brain Barrier Disruption Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16868082 Noninvasive Transesophageal Cardiac Thermal Ablation Using a 2-D Focused, Ultrasound Phased Array: a Simulation Study IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Jun, 2006 | Pubmed ID: 16846146 Uterine Leiomyomas: MR Imaging-based Thermometry and Thermal Dosimetry During Focused Ultrasound Thermal Ablation Radiology. Jul, 2006 | Pubmed ID: 16793983 Does the Phase of Menstrual Cycle Affect MR-guided Focused Ultrasound Surgery of Uterine Leiomyomas? European Journal of Radiology. Aug, 2006 | Pubmed ID: 16766153 Pre-clinical Testing of a Phased Array Ultrasound System for MRI-guided Noninvasive Surgery of the Brain--a Primate Study European Journal of Radiology. Aug, 2006 | Pubmed ID: 16716552 Mechanism of Porphyrin-induced Sonodynamic Effect: Possible Role of Hyperthermia Radiation Research. Mar, 2006 | Pubmed ID: 16494518 Targeted Delivery of Antibodies Through the Blood-brain Barrier by MRI-guided Focused Ultrasound Biochemical and Biophysical Research Communications. Feb, 2006 | Pubmed ID: 16403441 MRI-guided Targeted Blood-brain Barrier Disruption with Focused Ultrasound: Histological Findings in Rabbits Ultrasound in Medicine & Biology. Nov, 2005 | Pubmed ID: 16286030 Transcranial Ultrasound Focus Reconstruction with Phase and Amplitude Correction IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Sep, 2005 | Pubmed ID: 16285450 Hyperthermia Combined with Radiation in Treatment of Locally Advanced Prostate Cancer is Associated with a Favourable Toxicity Profile International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Nov, 2005 | Pubmed ID: 16278168 Acoustic Transmission Losses and Field Alterations Due to Human Scalp Hair IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Aug, 2005 | Pubmed ID: 16245611 MR Imaging-controlled Focused Ultrasound Ablation: a Noninvasive Image-guided Surgery Magnetic Resonance Imaging Clinics of North America. Aug, 2005 | Pubmed ID: 16084419 A Novel Method for the Intracellular Delivery of SiRNA Using Microbubble-enhanced Focused Ultrasound Biochemical and Biophysical Research Communications. Sep, 2005 | Pubmed ID: 16081042 A Magnetic Resonance Imaging-compatible, Large-scale Array for Trans-skull Ultrasound Surgery and Therapy Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Aug, 2005 | Pubmed ID: 16040827 Scanning Path Optimization for Ultrasound Surgery Physics in Medicine and Biology. Aug, 2005 | Pubmed ID: 16030378 Focal Beam Distortion and Treatment Planning in Abdominal Focused Ultrasound Surgery Medical Physics. May, 2005 | Pubmed ID: 15984679 MRI-guided Ultrasonic Heating Allows Spatial Control of Exogenous Luciferase in Canine Prostate Ultrasound in Medicine & Biology. Jul, 2005 | Pubmed ID: 15972202 A New Ultrasound Method for Determining the Acoustic Phase Shifts Caused by the Skull Bone Ultrasound in Medicine & Biology. Jun, 2005 | Pubmed ID: 15936493 Intracellular Delivery of Bak BH3 Peptide by Microbubble-enhanced Ultrasound Pharmaceutical Research. May, 2005 | Pubmed ID: 15906165 A Full-wave Helmholtz Model for Continuous-wave Ultrasound Transmission IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Mar, 2005 | Pubmed ID: 15857048 A Numerical Study of Transcranial Focused Ultrasound Beam Propagation at Low Frequency Physics in Medicine and Biology. Apr, 2005 | Pubmed ID: 15815098 Local and Reversible Blood-brain Barrier Disruption by Noninvasive Focused Ultrasound at Frequencies Suitable for Trans-skull Sonications NeuroImage. Jan, 2005 | Pubmed ID: 15588592 Noninvasive Thermal Ablation of Hepatocellular Carcinoma by Using Magnetic Resonance Imaging-guided Focused Ultrasound Gastroenterology. Nov, 2004 | Pubmed ID: 15508090 Patterns of Thermal Deposition in the Skull During Transcranial Focused Ultrasound Surgery IEEE Transactions on Bio-medical Engineering. Oct, 2004 | Pubmed ID: 15490817 Cellular Mechanisms of the Blood-brain Barrier Opening Induced by Ultrasound in Presence of Microbubbles Ultrasound in Medicine & Biology. Jul, 2004 | Pubmed ID: 15313330 500-element Ultrasound Phased Array System for Noninvasive Focal Surgery of the Brain: a Preliminary Rabbit Study with Ex Vivo Human Skulls Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jul, 2004 | Pubmed ID: 15236372 Apoptosis Signals in Lymphoblasts Induced by Focused Ultrasound FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2004 | Pubmed ID: 15231731 Simulation Study for Thermal Dose Optimization in Ultrasound Surgery of the Breast Medical Physics. May, 2004 | Pubmed ID: 15191322 MRI Monitoring of Heating Produced by Ultrasound Absorption in the Skull: in Vivo Study in Pigs Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. May, 2004 | Pubmed ID: 15122691 MRI Investigation of the Threshold for Thermally Induced Blood-brain Barrier Disruption and Brain Tissue Damage in the Rabbit Brain Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. May, 2004 | Pubmed ID: 15122673 Optical Monitoring of Ultrasound-induced Bioeffects in Glass Catfish Ultrasound in Medicine & Biology. Jan, 2004 | Pubmed ID: 14962610 Heat-activated Liposomal MR Contrast Agent: Initial in Vivo Results in Rabbit Liver and Kidney Radiology. Mar, 2004 | Pubmed ID: 14764890 Feasibility of Internally Referenced Brain Temperature Imaging with a Metabolite Signal Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine. Apr, 2003 | Pubmed ID: 16210815 Forward Planar Projection Through Layered Media IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Dec, 2003 | Pubmed ID: 14761040 Modeling of Anomalies Due to Hydrophones in Continuous-wave Ultrasound Fields IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Nov, 2003 | Pubmed ID: 14682632 Localized Harmonic Motion Imaging: Theory, Simulations and Experiments Ultrasound in Medicine & Biology. Oct, 2003 | Pubmed ID: 14597337 Ultrasound-mediated Cavitation Thresholds of Liquid Perfluorocarbon Droplets in Vitro Ultrasound in Medicine & Biology. Sep, 2003 | Pubmed ID: 14553814 The Use of Ultrasound-stimulated Acoustic Emission in the Monitoring of Modulus Changes with Temperature Ultrasonics. Jul, 2003 | Pubmed ID: 12788215 MRI-guided Focused Ultrasound Surgery in the Brain: Tests in a Primate Model Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jun, 2003 | Pubmed ID: 12768598 The Threshold for Brain Damage in Rabbits Induced by Bursts of Ultrasound in the Presence of an Ultrasound Contrast Agent (Optison) Ultrasound in Medicine & Biology. Mar, 2003 | Pubmed ID: 12706199 MR Imaging-guided Focused Ultrasound Surgery of Uterine Leiomyomas: a Feasibility Study Radiology. Mar, 2003 | Pubmed ID: 12616023 Interlaboratory Acoustic Power Measurement Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Feb, 2003 | Pubmed ID: 12562125 Intraoperative Magnetic Resonance Imaging and Magnetic Resonance Imaging-guided Therapy for Brain Tumors Neuroimaging Clinics of North America. Nov, 2002 | Pubmed ID: 12687918 A Unified Model for the Speed of Sound in Cranial Bone Based on Genetic Algorithm Optimization Physics in Medicine and Biology. Nov, 2002 | Pubmed ID: 12476974 Bio-acoustic Thermal Lensing and Nonlinear Propagation in Focused Ultrasound Surgery Using Large Focal Spots: a Parametric Study Physics in Medicine and Biology. Jun, 2002 | Pubmed ID: 12108775 Association of Rectal Toxicity with Thermal Dose Parameters in Treatment of Locally Advanced Prostate Cancer with Radiation and Hyperthermia International Journal of Radiation Oncology, Biology, Physics. Jul, 2002 | Pubmed ID: 12095557 Correlation of Ultrasound Phase with Physical Skull Properties Ultrasound in Medicine & Biology. May, 2002 | Pubmed ID: 12079698 Magnetic Resonance Image-guided Focused Ultrasound Surgery Cancer Journal (Sudbury, Mass.). May-Jun, 2002 | Pubmed ID: 12075696 Micro-receiver Guided Transcranial Beam Steering IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Apr, 2002 | Pubmed ID: 11989700 The Temperature Dependence of Ultrasound-stimulated Acoustic Emission Ultrasound in Medicine & Biology. Mar, 2002 | Pubmed ID: 11978413 The Use of Quantitative Temperature Images to Predict the Optimal Power for Focused Ultrasound Surgery: in Vivo Verification in Rabbit Muscle and Brain Medical Physics. Mar, 2002 | Pubmed ID: 11929019 Effects of Parameter Errors in the Simulation of Transcranial Focused Ultrasound Physics in Medicine and Biology. Jan, 2002 | Pubmed ID: 11814226 Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery Ultrasound in Medicine & Biology. | Pubmed ID: 32165014 वास्तविक समय Intravital Multiphoton माइक्रोस्कोपी केंद्रित अल्ट्रासाउंड और Microbubble उपचार की कल्पना करने के लिए रक्त मस्तिष्क बाधा पारगम्यता बढ़ाने के लिए Charissa Poon1,2, Melina Mühlenpfordt*3, Marieke Olsman*3, Spiros Kotopoulis4,5, Catharina de Lange Davies3, Kullervo Hynynen1,2,6 1Physical Sciences Platform, Sunnybrook Research Institute, 2Institute of Biomedical Engineering, University of Toronto, 3Department of Physics, Norwegian University of Science and Technology, 4Department of Clinical Medicine, University of Bergen, 5Exact Therapeutics AS, 6Department of Medical Biophysics, University of Toronto JoVE 62235 Bioingegneria एमआरआई-चिकित्सकीय दुर्दम्य आवश्यक कंपन के साथ रोगियों के लिए निर्देशित ध्यान केंद्रित अल्ट्रासाउंड Thalamotomy Ying Meng1, Yuexi Huang2, Benjamin Solomon2, Kullervo Hynynen2, Nadia Scantlebury1, Michael L. Schwartz1, Nir Lipsman1 1Division of Neurosurgery, Sunnybrook Health Sciences Centre, 2Sunnybrook Research Institute, Sunnybrook Health Sciences Centre JoVE 56365 Medicina रक्त मस्तिष्क बाधा के विघटन एमआरआई निर्देशित एक चूहे मॉडल में Transcranial केंद्रित अल्ट्रासाउंड का उपयोग Meaghan A. O'Reilly1, Adam C. Waspe1,2, Rajiv Chopra1,2, Kullervo Hynynen1,3 1Imaging Research, Sunnybrook Research Institute, 2Department of Medical Biophysics, University of Toronto, 3Department of Medical Biophysics, and Institute of Biomaterials & Biomedical Engineering (IBBME), University of Toronto JoVE 3555 Medicina
वास्तविक समय Intravital Multiphoton माइक्रोस्कोपी केंद्रित अल्ट्रासाउंड और Microbubble उपचार की कल्पना करने के लिए रक्त मस्तिष्क बाधा पारगम्यता बढ़ाने के लिए Charissa Poon1,2, Melina Mühlenpfordt*3, Marieke Olsman*3, Spiros Kotopoulis4,5, Catharina de Lange Davies3, Kullervo Hynynen1,2,6 1Physical Sciences Platform, Sunnybrook Research Institute, 2Institute of Biomedical Engineering, University of Toronto, 3Department of Physics, Norwegian University of Science and Technology, 4Department of Clinical Medicine, University of Bergen, 5Exact Therapeutics AS, 6Department of Medical Biophysics, University of Toronto JoVE 62235 Bioingegneria
एमआरआई-चिकित्सकीय दुर्दम्य आवश्यक कंपन के साथ रोगियों के लिए निर्देशित ध्यान केंद्रित अल्ट्रासाउंड Thalamotomy Ying Meng1, Yuexi Huang2, Benjamin Solomon2, Kullervo Hynynen2, Nadia Scantlebury1, Michael L. Schwartz1, Nir Lipsman1 1Division of Neurosurgery, Sunnybrook Health Sciences Centre, 2Sunnybrook Research Institute, Sunnybrook Health Sciences Centre JoVE 56365 Medicina
रक्त मस्तिष्क बाधा के विघटन एमआरआई निर्देशित एक चूहे मॉडल में Transcranial केंद्रित अल्ट्रासाउंड का उपयोग Meaghan A. O'Reilly1, Adam C. Waspe1,2, Rajiv Chopra1,2, Kullervo Hynynen1,3 1Imaging Research, Sunnybrook Research Institute, 2Department of Medical Biophysics, University of Toronto, 3Department of Medical Biophysics, and Institute of Biomaterials & Biomedical Engineering (IBBME), University of Toronto JoVE 3555 Medicina
