Larry Kagemann Department of Ophthalmology, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center University of Pittsburgh School of Medicine Biography Publications Institution JoVE Articles Larry Kagemann has not added a biography. If you are Larry Kagemann and would like to personalize this page please email our Author Liaison for assistance. Publications Histogram Matching Extends Acceptable Signal Strength Range on Optical Coherence Tomography Images Investigative Ophthalmology & Visual Science. Jun, 2015 | Pubmed ID: 26066749 Agreement Among Graders on Heidelberg Retina Tomograph (HRT) Topographic Change Analysis (TCA) Glaucoma Progression Interpretation The British Journal of Ophthalmology. Apr, 2015 | Pubmed ID: 25336573 In Vivo Three-dimensional Characterization of the Healthy Human Lamina Cribrosa with Adaptive Optics Spectral-domain Optical Coherence Tomography Investigative Ophthalmology & Visual Science. Oct, 2014 | Pubmed ID: 25228539 A Laser-induced Mouse Model with Long-term Intraocular Pressure Elevation PloS One. 2014 | Pubmed ID: 25216052 Repeatability of in Vivo 3D Lamina Cribrosa Microarchitecture Using Adaptive Optics Spectral Domain Optical Coherence Tomography Biomedical Optics Express. Apr, 2014 | Pubmed ID: 24761293 Reproducibility of In-vivo OCT Measured Three-dimensional Human Lamina Cribrosa Microarchitecture PloS One. 2014 | Pubmed ID: 24747957 Gold Nanorods As a Contrast Agent for Doppler Optical Coherence Tomography PloS One. 2014 | Pubmed ID: 24595044 Characterisation of Schlemm's Canal Cross-sectional Area The British Journal of Ophthalmology. Jul, 2014 | Pubmed ID: 24590558 IOP Elevation Reduces Schlemm's Canal Cross-sectional Area Investigative Ophthalmology & Visual Science. Mar, 2014 | Pubmed ID: 24526436 In Vivo Lamina Cribrosa Micro-architecture in Healthy and Glaucomatous Eyes As Assessed by Optical Coherence Tomography Investigative Ophthalmology & Visual Science. Dec, 2013 | Pubmed ID: 24302585 Automated Lamina Cribrosa Microstructural Segmentation in Optical Coherence Tomography Scans of Healthy and Glaucomatous Eyes Biomedical Optics Express. 2013 | Pubmed ID: 24298418 Signal Normalization Reduces Systematic Measurement Differences Between Spectral-domain Optical Coherence Tomography Devices Investigative Ophthalmology & Visual Science. Nov, 2013 | Pubmed ID: 24114534 Imaging of the Lamina Cribrosa in Glaucoma: Perspectives of Pathogenesis and Clinical Applications Current Eye Research. Sep, 2013 | Pubmed ID: 23768229 Individual A-scan Signal Normalization Between Two Spectral Domain Optical Coherence Tomography Devices Investigative Ophthalmology & Visual Science. May, 2013 | Pubmed ID: 23611992 Three-dimensional Spectral-domain Optical Coherence Tomography Data Analysis for Glaucoma Detection PloS One. 2013 | Pubmed ID: 23408988 High Dynamic Range Imaging Concept-based Signal Enhancement Method Reduced the Optical Coherence Tomography Measurement Variability Investigative Ophthalmology & Visual Science. Jan, 2013 | Pubmed ID: 23299477 Detection of Glaucoma Progression by Population and Individual Derived Variability Criteria The British Journal of Ophthalmology. Apr, 2013 | Pubmed ID: 23203702 Spectral-domain Optical Coherence Tomography As a Noninvasive Method to Assess Damaged and Regenerating Adult Zebrafish Retinas Investigative Ophthalmology & Visual Science. 2012 | Pubmed ID: 23093132 Inflammatory Response to Intravitreal Injection of Gold Nanorods The British Journal of Ophthalmology. Dec, 2012 | Pubmed ID: 23087415 Glaucoma Discrimination of Segmented Cirrus Spectral Domain Optical Coherence Tomography (SD-OCT) Macular Scans The British Journal of Ophthalmology. Nov, 2012 | Pubmed ID: 22914498 Volumetric Quantification of in Vitro Sonothrombolysis with Microbubbles Using High-resolution Optical Coherence Tomography Journal of Biomedical Optics. Jul, 2012 | Pubmed ID: 22894458 Visualization of the Conventional Outflow Pathway in the Living Human Eye Ophthalmology. Aug, 2012 | Pubmed ID: 22683063 Evaluating Objective and Subjective Quantitative Parameters at the Initial Visit to Predict Future Glaucomatous Visual Field Progression Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye. Sep-Oct, 2012 | Pubmed ID: 22658308 Comparison of Retinal Nerve Fiber Layer Thickness Measurement Bias and Imprecision Across Three Spectral-domain Optical Coherence Tomography Devices Investigative Ophthalmology & Visual Science. Jun, 2012 | Pubmed ID: 22538423 Morphometric Analysis of Aqueous Humor Outflow Structures with Spectral-domain Optical Coherence Tomography Investigative Ophthalmology & Visual Science. Aug, 2012 | Pubmed ID: 22499987 The Optic Nerve Head As a Robust Biomechanical System Investigative Ophthalmology & Visual Science. May, 2012 | Pubmed ID: 22427598 Optical Coherence Tomography As a Rapid, Accurate, Noncontact Method of Visualizing the Palisades of Vogt Investigative Ophthalmology & Visual Science. Mar, 2012 | Pubmed ID: 22266521 Alignment of 3-D Optical Coherence Tomography Scans to Correct Eye Movement Using a Particle Filtering IEEE Transactions on Medical Imaging. Jul, 2012 | Pubmed ID: 22231171 Variation in Optical Coherence Tomography Signal Quality As an Indicator of Retinal Nerve Fibre Layer Segmentation Error The British Journal of Ophthalmology. Apr, 2012 | Pubmed ID: 21900227 Retinal Nerve Fibre Layer and Visual Function Loss in Glaucoma: the Tipping Point The British Journal of Ophthalmology. Jan, 2012 | Pubmed ID: 21478200 Use of Colour Doppler Imaging in Ocular Blood Flow Research Acta Ophthalmologica. Dec, 2011 | Pubmed ID: 21989301 3D Visualization of Aqueous Humor Outflow Structures In-situ in Humans Experimental Eye Research. Sep, 2011 | Pubmed ID: 21514296 Optical Coherence Tomography: History, Current Status, and Laboratory Work Investigative Ophthalmology & Visual Science. Apr, 2011 | Pubmed ID: 21493951 Optic Nerve Crush Mice Followed Longitudinally with Spectral Domain Optical Coherence Tomography Investigative Ophthalmology & Visual Science. Apr, 2011 | Pubmed ID: 21398282 Direct Scanning of Pathology Specimens Using Spectral Domain Optical Coherence Tomography: a Pilot Study Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye. Nov-Dec, 2010 | Pubmed ID: 21117602 Automated Volumetric Evaluation of Stereoscopic Disc Photography Optics Express. May, 2010 | Pubmed ID: 20588996 Reproducibility of Spectral-domain Optical Coherence Tomography Total Retinal Thickness Measurements in Mice Investigative Ophthalmology & Visual Science. Dec, 2010 | Pubmed ID: 20574022 Three Dimensional Optical Coherence Tomography Imaging: Advantages and Advances Progress in Retinal and Eye Research. Nov, 2010 | Pubmed ID: 20542136 In Vitro Simulation of the First Technique for Non-invasive Measurement of Volumetric Ophthalmic Artery Blood Flow in Humans Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye. May-Jun, 2010 | Pubmed ID: 20507024 Identification and Assessment of Schlemm's Canal by Spectral-domain Optical Coherence Tomography Investigative Ophthalmology & Visual Science. Aug, 2010 | Pubmed ID: 20237244 Retinal Nerve Fiber Layer Thickness Measurement Comparability Between Time Domain Optical Coherence Tomography (OCT) and Spectral Domain OCT Investigative Ophthalmology & Visual Science. Feb, 2010 | Pubmed ID: 19737886 Ocular Blood Flow and Oxygen Delivery to the Retina in Primary Open-angle Glaucoma Patients: the Addition of Dorzolamide to Timolol Monotherapy Acta Ophthalmologica. Feb, 2010 | Pubmed ID: 19706018 Effects of Age on Optical Coherence Tomography Measurements of Healthy Retinal Nerve Fiber Layer, Macula, and Optic Nerve Head Ophthalmology. Jun, 2009 | Pubmed ID: 19376593 Visualization of 3-D High Speed Ultrahigh Resolution Optical Coherence Tomographic Data Identifies Structures Visible in 2D Frames Optics Express. Mar, 2009 | Pubmed ID: 19259256 Comparison of StratusOCT and Cirrus HD-OCT Imaging in Macular Diseases Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye. Jan-Feb, 2009 | Pubmed ID: 19205492 Three-dimensional Optical Coherence Tomography (3D-OCT) Image Enhancement with Segmentation-free Contour Modeling C-mode Investigative Ophthalmology & Visual Science. Mar, 2009 | Pubmed ID: 18952923 Validation of Spectral Domain Optical Coherence Tomographic Doppler Shifts Using an in Vitro Flow Model Investigative Ophthalmology & Visual Science. Feb, 2009 | Pubmed ID: 18824730 Repeated, Noninvasive, High Resolution Spectral Domain Optical Coherence Tomography Imaging of Zebrafish Embryos Molecular Vision. 2008 | Pubmed ID: 19052656 Ultrahigh-resolution Spectral Domain Optical Coherence Tomography Imaging of the Lamina Cribrosa Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye. Jul-Aug, 2008 | Pubmed ID: 18777881 Assessing the Relationship Between Central Corneal Thickness and Retinal Nerve Fiber Layer Thickness in Healthy Subjects American Journal of Ophthalmology. Oct, 2008 | Pubmed ID: 18657796 Dye Dependent Differences in Arteriovenous Passage Times: a Comparison of Indocyanine Green and Fluorescein Sodium Dye Analysis Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye. May-Jun, 2008 | Pubmed ID: 18556940 Optical Coherence Tomography Scan Circle Location and Mean Retinal Nerve Fiber Layer Measurement Variability Investigative Ophthalmology & Visual Science. Jun, 2008 | Pubmed ID: 18515577 Measuring and Interpreting Ocular Blood Flow and Metabolism in Glaucoma Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie. Jun, 2008 | Pubmed ID: 18443609 Automated Assessment of the Optic Nerve Head on Stereo Disc Photographs Investigative Ophthalmology & Visual Science. Jun, 2008 | Pubmed ID: 18326698 Comparison of Optic Disc Margin Identified by Color Disc Photography and High-speed Ultrahigh-resolution Optical Coherence Tomography Archives of Ophthalmology (Chicago, Ill. : 1960). Jan, 2008 | Pubmed ID: 18195219 Improved Visualization of Glaucomatous Retinal Damage Using High-speed Ultrahigh-resolution Optical Coherence Tomography Ophthalmology. May, 2008 | Pubmed ID: 17884170 Comparison of Parameters from Heidelberg Retina Tomographs 2 and 3 Ophthalmology. Apr, 2008 | Pubmed ID: 17719642 Spectral Oximetry Assessed with High-speed Ultra-high-resolution Optical Coherence Tomography Journal of Biomedical Optics. Jul-Aug, 2007 | Pubmed ID: 17867801 In Vivo Corneal High-speed, Ultra High-resolution Optical Coherence Tomography Archives of Ophthalmology (Chicago, Ill. : 1960). Aug, 2007 | Pubmed ID: 17698748 Optical Coherence Tomography and Histologic Measurements of Nerve Fiber Layer Thickness in Normal and Glaucomatous Monkey Eyes Investigative Ophthalmology & Visual Science. Aug, 2007 | Pubmed ID: 17652734 Peripapillary Nerve Fiber Layer Thickness Profile Determined with High Speed, Ultrahigh Resolution Optical Coherence Tomography High-density Scanning Investigative Ophthalmology & Visual Science. Jul, 2007 | Pubmed ID: 17591885 The Relationship Between Retrobulbar and Choroidal Hemodynamics in Non-neovascular Age-related Macular Degeneration Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye. May-Jun, 2007 | Pubmed ID: 17552388 Peripapillary Schisis in Glaucoma Patients with Narrow Angles and Increased Intraocular Pressure American Journal of Ophthalmology. Apr, 2007 | Pubmed ID: 17386284 Glaucoma Detection with Matrix and Standard Achromatic Perimetry The British Journal of Ophthalmology. Jul, 2007 | Pubmed ID: 17215267 Glaucoma Detection with the Heidelberg Retina Tomograph 3 Ophthalmology. Mar, 2007 | Pubmed ID: 17141321 Automatic Retinal Oximetry Investigative Ophthalmology & Visual Science. Nov, 2006 | Pubmed ID: 17065521 Persistence of Cloquet's Canal in Normal Healthy Eyes American Journal of Ophthalmology. Nov, 2006 | Pubmed ID: 17056372 The Effects of Droperidol in Perforating Keratoplasty Ophthalmologica. Journal International D'ophtalmologie. International Journal of Ophthalmology. Zeitschrift Für Augenheilkunde. 2006 | Pubmed ID: 16785755 Advanced Scanning Methods with Tracking Optical Coherence Tomography Optics Express. Oct, 2005 | Pubmed ID: 19498823 Matrix Metalloproteinase Gelatinase B (MMP-9) is Associated with Leaking Glaucoma Filtering Blebs Experimental Eye Research. Oct, 2005 | Pubmed ID: 16185954 An Update on Retinal Circulation Assessment Technologies Current Eye Research. Dec, 2003 | Pubmed ID: 14704917 Comparison of Ocular Hemodynamics Measured by a New Retinal Blood Flowmeter and Color Doppler Imaging Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye. Jul-Aug, 2003 | Pubmed ID: 12875469 A Review of Methods for Human Retinal Oximetry Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye. Mar-Apr, 2003 | Pubmed ID: 12665234 Improving the Analysis of Arteriovenous Passage Times Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Nov, 2002 | Pubmed ID: 12486520 Nocturnal Blood Pressure Reduction: Effect on Retrobulbar Hemodynamics in Glaucoma Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. May, 2002 | Pubmed ID: 12073060 Choroidal Perfusion Perturbations in Non-neovascular Age Related Macular Degeneration The British Journal of Ophthalmology. Feb, 2002 | Pubmed ID: 11815349 Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye Larry Kagemann1,2, Bo Wang2, Gadi Wollstein1, Hiroshi Ishikawa1,2, Brandon Mentley1, Ian Sigal1,2,3, Richard A Bilonick1,4, Joel S Schuman1,2,3 1Department of Ophthalmology, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, University of Pittsburgh School of Medicine, 2Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, 3The McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, 4Deptartment of Biostatistics, Graduate School of Public Health, University of Pittsburgh JoVE 52611 Medicina
Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye Larry Kagemann1,2, Bo Wang2, Gadi Wollstein1, Hiroshi Ishikawa1,2, Brandon Mentley1, Ian Sigal1,2,3, Richard A Bilonick1,4, Joel S Schuman1,2,3 1Department of Ophthalmology, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, University of Pittsburgh School of Medicine, 2Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, 3The McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, 4Deptartment of Biostatistics, Graduate School of Public Health, University of Pittsburgh JoVE 52611 Medicina