Lloyd A. Greene Department of Pathology and Cell Biology Columbia University Biography Publications Institution JoVE Articles Lloyd A. Greene has not added a biography. If you are Lloyd A. Greene and would like to personalize this page please email our Author Liaison for assistance. Publications Sh3rf2/POSHER Protein Promotes Cell Survival by Ring-mediated Proteasomal Degradation of the C-Jun N-terminal Kinase Scaffold POSH (Plenty of SH3s) Protein The Journal of Biological Chemistry. Jan, 2012 | Pubmed ID: 22128169 Reciprocal Actions of ATF5 and Shh in Proliferation of Cerebellar Granule Neuron Progenitor Cells Developmental Neurobiology. Sep, 2011 | Pubmed ID: 22095825 Akt As a Victim, Villain and Potential Hero in Parkinson's Disease Pathophysiology and Treatment Cellular and Molecular Neurobiology. Oct, 2011 | Pubmed ID: 21547489 Gata2 is Required for Migration and Differentiation of Retinorecipient Neurons in the Superior Colliculus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2011 | Pubmed ID: 21430145 RTP801/REDD1 Regulates the Timing of Cortical Neurogenesis and Neuron Migration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2011 | Pubmed ID: 21368030 Sertad1 Plays an Essential Role in Developmental and Pathological Neuron Death The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2010 | Pubmed ID: 20237268 Rapamycin Protects Against Neuron Death in in Vitro and in Vivo Models of Parkinson's Disease The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2010 | Pubmed ID: 20089925 Cbl Negatively Regulates JNK Activation and Cell Death Cell Research. Aug, 2009 | Pubmed ID: 19546888 Identification of a Novel DNA Binding Site and a Transcriptional Target for Activating Transcription Factor 5 in C6 Glioma and Mcf-7 Breast Cancer Cells Molecular Cancer Research : MCR. Jun, 2009 | Pubmed ID: 19531563 Cell Death Pathways in Parkinson's Disease: Proximal Triggers, Distal Effectors, and Final Steps Apoptosis : an International Journal on Programmed Cell Death. Apr, 2009 | Pubmed ID: 19165601 The Transcription Factor ATF5: Role in Neurodevelopment and Neural Tumors Journal of Neurochemistry. Jan, 2009 | Pubmed ID: 19046351 RTP801 is Induced in Parkinson's Disease and Mediates Neuron Death by Inhibiting Akt Phosphorylation/activation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2008 | Pubmed ID: 19118169 Glucagon-like Peptide-1 (GLP-1) Diminishes Neuronal Degeneration and Death Caused by NGF Deprivation by Suppressing Bim Induction Neurochemical Research. Sep, 2008 | Pubmed ID: 18351462 Identification of POSH2, a Novel Homologue of the C-Jun N-terminal Kinase Scaffold Protein POSH Developmental Neuroscience. 2007 | Pubmed ID: 17762203 Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways The Journal of Biological Chemistry. Oct, 2007 | Pubmed ID: 17702754 The Transcription Factor ATF5 is Widely Expressed in Carcinomas, and Interference with Its Function Selectively Kills Neoplastic, but Not Nontransformed, Breast Cell Lines International Journal of Cancer. Journal International Du Cancer. May, 2007 | Pubmed ID: 17266024 Bim is Elevated in Alzheimer's Disease Neurons and is Required for Beta-amyloid-induced Neuronal Apoptosis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2007 | Pubmed ID: 17251431 Cell Cycle Molecules Define a Pathway Required for Neuron Death in Development and Disease Biochimica Et Biophysica Acta. Apr, 2007 | Pubmed ID: 17229557 Proapoptotic Nix Activates the JNK Pathway by Interacting with POSH and Mediates Death in a Parkinson Disease Model The Journal of Biological Chemistry. Jan, 2007 | Pubmed ID: 17095503 RTP801 is Elevated in Parkinson Brain Substantia Nigral Neurons and Mediates Death in Cellular Models of Parkinson's Disease by a Mechanism Involving Mammalian Target of Rapamycin Inactivation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2006 | Pubmed ID: 17005863 Direct Interaction of the Molecular Scaffolds POSH and JIP is Required for Apoptotic Activation of JNKs The Journal of Biological Chemistry. Jun, 2006 | Pubmed ID: 16571722 Activation of the Apoptotic JNK Pathway Through the Rac1-binding Scaffold Protein POSH Methods in Enzymology. 2006 | Pubmed ID: 16472680 Siah1 Interacts with the Scaffold Protein POSH to Promote JNK Activation and Apoptosis The Journal of Biological Chemistry. Jan, 2006 | Pubmed ID: 16230351 You Can't Go Home Again: Transcriptionally Driven Alteration of Cell Signaling by NGF Neurochemical Research. Oct, 2005 | Pubmed ID: 16341597 Regulation of Apoptotic C-Jun N-terminal Kinase Signaling by a Stabilization-based Feed-forward Loop Molecular and Cellular Biology. Nov, 2005 | Pubmed ID: 16260609 Puma and P53 Play Required Roles in Death Evoked in a Cellular Model of Parkinson Disease Neurochemical Research. Jun-Jul, 2005 | Pubmed ID: 16187218 Bim is a Direct Target of a Neuronal E2F-dependent Apoptotic Pathway The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2005 | Pubmed ID: 16162916 CHOP/GADD153 is a Mediator of Apoptotic Death in Substantia Nigra Dopamine Neurons in an in Vivo Neurotoxin Model of Parkinsonism Journal of Neurochemistry. Nov, 2005 | Pubmed ID: 16135078 ATF5 Regulates the Proliferation and Differentiation of Oligodendrocytes Molecular and Cellular Neurosciences. Jul, 2005 | Pubmed ID: 15950153 Downregulation of Activating Transcription Factor 5 is Required for Differentiation of Neural Progenitor Cells into Astrocytes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2005 | Pubmed ID: 15829641 Regulation of Neuron Survival and Death by P130 and Associated Chromatin Modifiers Genes & Development. Mar, 2005 | Pubmed ID: 15769944 Analysis of Gene Expression Changes in a Cellular Model of Parkinson Disease Neurobiology of Disease. Feb, 2005 | Pubmed ID: 15649696 Highly Efficient Small Interfering RNA Delivery to Primary Mammalian Neurons Induces MicroRNA-like Effects Before MRNA Degradation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2004 | Pubmed ID: 15537872 B-myb and C-myb Play Required Roles in Neuronal Apoptosis Evoked by Nerve Growth Factor Deprivation and DNA Damage The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2004 | Pubmed ID: 15470138 Malignant Pheochromocytoma: Current Status and Initiatives for Future Progress Endocrine-related Cancer. Sep, 2004 | Pubmed ID: 15369446 Regulated Expression of ATF5 is Required for the Progression of Neural Progenitor Cells to Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2003 | Pubmed ID: 12805299 POSH Acts As a Scaffold for a Multiprotein Complex That Mediates JNK Activation in Apoptosis The EMBO Journal. Jan, 2003 | Pubmed ID: 12514131 Endoplasmic Reticulum Stress and the Unfolded Protein Response in Cellular Models of Parkinson's Disease The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2002 | Pubmed ID: 12486162 The Basic Region and Leucine Zipper Transcription Factor MafK is a New Nerve Growth Factor-responsive Immediate Early Gene That Regulates Neurite Outgrowth The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2002 | Pubmed ID: 12388604 Nerve Growth Factor (NGF) Down-regulates the Bcl-2 Homology 3 (BH3) Domain-only Protein Bim and Suppresses Its Proapoptotic Activity by Phosphorylation The Journal of Biological Chemistry. Dec, 2002 | Pubmed ID: 12388545 Nerve Growth Factor Selectively Regulates Expression of Transcripts Encoding Ribosomal Proteins BMC Neuroscience. 2002 | Pubmed ID: 11922865 Protocolo para Neurônios Cultivar Sympathetic de Gânglios Superior Rat Cervical (SCG) Neela Zareen1, Lloyd A. Greene2 1Department of Biology, Columbia University, 2Department of Pathology and Cell Biology, Columbia University JoVE 988 Biologia Isolamento e Cultura de Pós-Natal do rato Cerebelar Granule Células Progenitoras Neuron e Neurônios Hae Young Lee1, Lloyd A. Greene2, Carol A. Mason2,3, M. Chiara Manzini2,4 1Department of Genetics and Development, Columbia University, 2Department of Pathology and Cell Biology, Columbia University, 3Department of Neuroscience, Columbia University, 4Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School JoVE 990 Biologia
Protocolo para Neurônios Cultivar Sympathetic de Gânglios Superior Rat Cervical (SCG) Neela Zareen1, Lloyd A. Greene2 1Department of Biology, Columbia University, 2Department of Pathology and Cell Biology, Columbia University JoVE 988 Biologia
Isolamento e Cultura de Pós-Natal do rato Cerebelar Granule Células Progenitoras Neuron e Neurônios Hae Young Lee1, Lloyd A. Greene2, Carol A. Mason2,3, M. Chiara Manzini2,4 1Department of Genetics and Development, Columbia University, 2Department of Pathology and Cell Biology, Columbia University, 3Department of Neuroscience, Columbia University, 4Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School JoVE 990 Biologia