Marcelo D. Carattino Renal-Electrolyte Division, Department of Medicine University of Pittsburgh Biography Publications Institution JoVE Articles Marcelo D. Carattino has not added a biography. If you are Marcelo D. Carattino and would like to personalize this page please email our Author Liaison for assistance. Publications Functional Characterization of Ion Channels Expressed in Kidney Organoids Derived from Human Induced Pluripotent Stem Cells American Journal of Physiology. Renal Physiology. Oct, 2022 | Pubmed ID: 35979965 Studies of Ultrastructure, Gene Expression, and Marker Analysis Reveal That Mouse Bladder PDGFRA Interstitial Cells Are Fibroblasts American Journal of Physiology. Renal Physiology. 09, 2022 | Pubmed ID: 35834272 Bladder Infection with Uropathogenic Increases the Excitability of Afferent Neurons American Journal of Physiology. Renal Physiology. 01, 2022 | Pubmed ID: 34779263 Acid-sensing Ion Channels Modulate Bladder Nociception American Journal of Physiology. Renal Physiology. 11, 2021 | Pubmed ID: 34514879 Functional Roles for PIEZO1 and PIEZO2 in Urothelial Mechanotransduction and Lower Urinary Tract Interoception JCI Insight. 10, 2021 | Pubmed ID: 34464353 The Urothelium: Life in a Liquid Environment Physiological Reviews. 10, 2020 | Pubmed ID: 32191559 Paraoxonase 3 Functions As a Chaperone to Decrease Functional Expression of the Epithelial Sodium Channel The Journal of Biological Chemistry. 04, 2020 | Pubmed ID: 32079677 Acid-sensing Ion Channels in Sensory Signaling American Journal of Physiology. Renal Physiology. 03, 2020 | Pubmed ID: 31984789 Molecular Determinants of Afferent Sensitization in a Rat Model of Cystitis with Urothelial Barrier Dysfunction Journal of Neurophysiology. 09, 2019 | Pubmed ID: 31314637 Expression and Distribution of PIEZO1 in the Mouse Urinary Tract American Journal of Physiology. Renal Physiology. Aug, 2019 | Pubmed ID: 31166705 Murine Epithelial Sodium (Na) Channel Regulation by Biliary Factors The Journal of Biological Chemistry. 06, 2019 | Pubmed ID: 31092599 Renal Sensory Nerves Increase Sympathetic Nerve Activity and Blood Pressure in 2-kidney 1-clip Hypertensive Mice Journal of Neurophysiology. 07, 2019 | Pubmed ID: 31091159 Urinary K Promotes Irritative Voiding Symptoms and Pain in the Face of Urothelial Barrier Dysfunction Scientific Reports. 04, 2019 | Pubmed ID: 30940909 Molecular Basis of Inhibition of Acid Sensing Ion Channel 1A by Diminazene PloS One. 2018 | Pubmed ID: 29782492 ASIC3 Fine-tunes Bladder Sensory Signaling American Journal of Physiology. Renal Physiology. 10, 2018 | Pubmed ID: 29561183 Cdc42 Activation Couples Fluid Shear Stress to Apical Endocytosis in Proximal Tubule Cells Physiological Reports. Oct, 2017 | Pubmed ID: 29038362 Expression and Analysis of Flow-regulated Ion Channels in Oocytes Bio-protocol. Apr, 2017 | Pubmed ID: 28670605 Urothelial Tight Junction Barrier Dysfunction Sensitizes Bladder Afferents ENeuro. May-Jun, 2017 | Pubmed ID: 28560313 Specific Palmitoyltransferases Associate with and Activate the Epithelial Sodium Channel The Journal of Biological Chemistry. 03, 2017 | Pubmed ID: 28154191 The Thumb Domain Mediates Acid-sensing Ion Channel Desensitization The Journal of Biological Chemistry. May, 2016 | Pubmed ID: 27015804 Cell-specific Regulation of L-WNK1 by Dietary K American Journal of Physiology. Renal Physiology. Jan, 2016 | Pubmed ID: 26662201 Increased Urothelial Paracellular Transport Promotes Cystitis American Journal of Physiology. Renal Physiology. Dec, 2015 | Pubmed ID: 26423859 Intracellular Na+ Regulates Epithelial Na+ Channel Maturation The Journal of Biological Chemistry. May, 2015 | Pubmed ID: 25767115 Prostasin Interacts with the Epithelial Na+ Channel and Facilitates Cleavage of the γ-subunit by a Second Protease American Journal of Physiology. Renal Physiology. Nov, 2014 | Pubmed ID: 25209858 Shear Stress-dependent Regulation of Apical Endocytosis in Renal Proximal Tubule Cells Mediated by Primary Cilia Proceedings of the National Academy of Sciences of the United States of America. Jun, 2014 | Pubmed ID: 24912170 Independent Contribution of Extracellular Proton Binding Sites to ASIC1a Activation The Journal of Biological Chemistry. Nov, 2013 | Pubmed ID: 24142696 Regulation of Large-conductance Ca2+-activated K+ Channels by WNK4 Kinase American Journal of Physiology. Cell Physiology. Oct, 2013 | Pubmed ID: 23885063 Bladder Filling and Voiding Affect Umbrella Cell Tight Junction Organization and Function American Journal of Physiology. Renal Physiology. Oct, 2013 | Pubmed ID: 23884145 ENaC Regulation by Proteases and Shear Stress Current Molecular Pharmacology. Mar, 2013 | Pubmed ID: 23547932 Gating Transitions in the Palm Domain of ASIC1a The Journal of Biological Chemistry. Feb, 2013 | Pubmed ID: 23300086 Role of the Wrist Domain in the Response of the Epithelial Sodium Channel to External Stimuli The Journal of Biological Chemistry. Dec, 2012 | Pubmed ID: 23144453 Cation Transport Goes with the Flow American Journal of Physiology. Renal Physiology. Sep, 2012 | Pubmed ID: 22739535 Inhibitory Tract Traps the Epithelial Na+ Channel in a Low Activity Conformation The Journal of Biological Chemistry. Jun, 2012 | Pubmed ID: 22511777 Contribution of Residues in Second Transmembrane Domain of ASIC1a Protein to Ion Selectivity The Journal of Biological Chemistry. Apr, 2012 | Pubmed ID: 22371494 TMPRSS4-dependent Activation of the Epithelial Sodium Channel Requires Cleavage of the γ-subunit Distal to the Furin Cleavage Site American Journal of Physiology. Renal Physiology. Jan, 2012 | Pubmed ID: 21993886 Structural Mechanisms Underlying the Function of Epithelial Sodium Channel/acid-sensing Ion Channel Current Opinion in Nephrology and Hypertension. Sep, 2011 | Pubmed ID: 21709553 Insights into the Mechanism of Pore Opening of Acid-sensing Ion Channel 1a The Journal of Biological Chemistry. May, 2011 | Pubmed ID: 21388961 Base of the Thumb Domain Modulates Epithelial Sodium Channel Gating The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21367859 Second Transmembrane Domain Modulates Epithelial Sodium Channel Gating in Response to Shear Stress American Journal of Physiology. Renal Physiology. May, 2011 | Pubmed ID: 21307123 Clues to Renal Sodium Retention American Journal of Physiology. Renal Physiology. Mar, 2011 | Pubmed ID: 21228112 Defining an Inhibitory Domain in the Gamma Subunit of the Epithelial Sodium Channel American Journal of Physiology. Renal Physiology. Oct, 2010 | Pubmed ID: 20630937 Conformational Changes Associated with Proton-dependent Gating of ASIC1a The Journal of Biological Chemistry. Dec, 2009 | Pubmed ID: 19858190 ENaC at the Cutting Edge: Regulation of Epithelial Sodium Channels by Proteases The Journal of Biological Chemistry. Jul, 2009 | Pubmed ID: 19401469 Novel Determinants of Epithelial Sodium Channel Gating Within Extracellular Thumb Domains The Journal of Biological Chemistry. Mar, 2009 | Pubmed ID: 19158091 Proteolytic Processing of the Epithelial Sodium Channel Gamma Subunit Has a Dominant Role in Channel Activation The Journal of Biological Chemistry. Sep, 2008 | Pubmed ID: 18650438 Effect of Aldosterone on BK Channel Expression in Mammalian Cortical Collecting Duct American Journal of Physiology. Renal Physiology. Sep, 2008 | Pubmed ID: 18579708 Defining an Inhibitory Domain in the Alpha-subunit of the Epithelial Sodium Channel American Journal of Physiology. Renal Physiology. Jan, 2008 | Pubmed ID: 18032549 Role of Proteolysis in the Activation of Epithelial Sodium Channels Current Opinion in Nephrology and Hypertension. Sep, 2007 | Pubmed ID: 17693760 Lack of a Role of Membrane-protein Interactions in Flow-dependent Activation of ENaC American Journal of Physiology. Renal Physiology. Jul, 2007 | Pubmed ID: 17459954 Epithelial Na+ Channels Are Fully Activated by Furin- and Prostasin-dependent Release of an Inhibitory Peptide from the Gamma-subunit The Journal of Biological Chemistry. Mar, 2007 | Pubmed ID: 17199078 The Epithelial Na+ Channel is Inhibited by a Peptide Derived from Proteolytic Processing of Its Alpha Subunit The Journal of Biological Chemistry. Jul, 2006 | Pubmed ID: 16690613 Epithelial Sodium Channel Inhibition by AMP-activated Protein Kinase in Oocytes and Polarized Renal Epithelial Cells The Journal of Biological Chemistry. May, 2005 | Pubmed ID: 15753079 Mutations in the Pore Region Modify Epithelial Sodium Channel Gating by Shear Stress The Journal of Biological Chemistry. Feb, 2005 | Pubmed ID: 15569663 Epithelial Sodium Channels Are Activated by Furin-dependent Proteolysis The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 15007080 Epithelial Na+ Channels Are Activated by Laminar Shear Stress The Journal of Biological Chemistry. Feb, 2004 | Pubmed ID: 14625286 Maturation of the Epithelial Na+ Channel Involves Proteolytic Processing of the Alpha- and Gamma-subunits The Journal of Biological Chemistry. Sep, 2003 | Pubmed ID: 12871941 Arachidonic Acid Regulates Surface Expression of Epithelial Sodium Channels The Journal of Biological Chemistry. Sep, 2003 | Pubmed ID: 12837767 Syntaxin 1A Regulates ENaC Via Domain-specific Interactions The Journal of Biological Chemistry. Apr, 2003 | Pubmed ID: 12562778 Real-Time Void Spot Assay Marianela G. Dalghi1, Nicolas Montalbetti1, Travis B. Wheeler2, Gerard Apodaca1, Marcelo D. Carattino1,2 1Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, 2Department of Cell Biology, University of Pittsburgh JoVE 64621 Comportamento Ex Vivo Analysis of Mechanically Activated Ca2+ Transients in Urothelial Cells Marcelo D. Carattino1,2, Wily G. Ruiz1, Gerard Apodaca1,2 1Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, 2Department of Cell Biology, University of Pittsburgh JoVE 64532 Medicina
Real-Time Void Spot Assay Marianela G. Dalghi1, Nicolas Montalbetti1, Travis B. Wheeler2, Gerard Apodaca1, Marcelo D. Carattino1,2 1Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, 2Department of Cell Biology, University of Pittsburgh JoVE 64621 Comportamento
Ex Vivo Analysis of Mechanically Activated Ca2+ Transients in Urothelial Cells Marcelo D. Carattino1,2, Wily G. Ruiz1, Gerard Apodaca1,2 1Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, 2Department of Cell Biology, University of Pittsburgh JoVE 64532 Medicina