Maria-Grazia De Simoni Department of Neuroscience IRCCS - Istituto di Ricerche Farmacologiche Mario Negri Biography Publications Institution JoVE Articles Maria-Grazia De Simoni has not added a biography. If you are Maria-Grazia De Simoni and would like to personalize this page please email our Author Liaison for assistance. Publications Changes of the GPR17 Receptor, a New Target for Neurorepair, in Neurons and Glial Cells in Patients with Traumatic Brain Injury Purinergic Signalling. Sep, 2013 | Pubmed ID: 23801362 Six-month Ischemic Mice Show Sensorimotor and Cognitive Deficits Associated with Brain Atrophy and Axonal Disorganization CNS Neuroscience & Therapeutics. Sep, 2013 | Pubmed ID: 23742688 Tumor Necrosis Factor in Traumatic Brain Injury: Effects of Genetic Deletion of P55 or P75 Receptor Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2013 | Pubmed ID: 23611870 CX3CR1 Deficiency Induces an Early Protective Inflammatory Environment in Ischemic Mice Glia. Jun, 2013 | Pubmed ID: 23440897 Targeting Mannose-binding Lectin Confers Long-lasting Protection with a Surprisingly Wide Therapeutic Window in Cerebral Ischemia Circulation. Sep, 2012 | Pubmed ID: 22879370 Proteomic Analysis of Mouse Brain Cortex Identifies Metabolic Down-regulation As a General Feature of Ischemic Pre-conditioning Journal of Neurochemistry. Sep, 2012 | Pubmed ID: 22804628 Temporal Pattern of Expression and Colocalization of Microglia/macrophage Phenotype Markers Following Brain Ischemic Injury in Mice Journal of Neuroinflammation. 2011 | Pubmed ID: 22152337 CX3CL1 is Neuroprotective in Permanent Focal Cerebral Ischemia in Rodents The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2011 | Pubmed ID: 22072684 Cytokines and Innate Inflammation in the Pathogenesis of Human Traumatic Brain Injury Progress in Neurobiology. Nov, 2011 | Pubmed ID: 21939729 Human Umbilical Cord Blood Mesenchymal Stem Cells Protect Mice Brain After Trauma Critical Care Medicine. Nov, 2011 | Pubmed ID: 21725237 Glial Cells Drive Preconditioning-induced Blood-brain Barrier Protection Stroke; a Journal of Cerebral Circulation. May, 2011 | Pubmed ID: 21474800 Long-lasting Protection in Brain Trauma by Endotoxin Preconditioning Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Sep, 2011 | Pubmed ID: 21468087 In Vivo Real-time Multiphoton Imaging of T Lymphocytes in the Mouse Brain After Experimental Stroke Stroke; a Journal of Cerebral Circulation. May, 2011 | Pubmed ID: 21441145 Glycogen Synthase Kinase-3 Inhibition Reduces Ischemic Cerebral Damage, Restores Impaired Mitochondrial Biogenesis and Prevents ROS Production Journal of Neurochemistry. Mar, 2011 | Pubmed ID: 21210815 Cerebrospinal Fluid Pentraxin 3 Early After Subarachnoid Hemorrhage is Associated with Vasospasm Intensive Care Medicine. Feb, 2011 | Pubmed ID: 21072498 Recombinant C1 Inhibitor in Brain Ischemic Injury Annals of Neurology. Sep, 2009 | Pubmed ID: 19798727 Alzheimer's Disease: Another Target for Heparin Therapy TheScientificWorldJournal. 2009 | Pubmed ID: 19734963 C-Jun N-terminal Kinase Pathway Activation in Human and Experimental Cerebral Contusion Journal of Neuropathology and Experimental Neurology. Sep, 2009 | Pubmed ID: 19680147 C1-inhibitor Attenuates Neurobehavioral Deficits and Reduces Contusion Volume After Controlled Cortical Impact Brain Injury in Mice Critical Care Medicine. Feb, 2009 | Pubmed ID: 19114897 Leptin is Induced in the Ischemic Cerebral Cortex and Exerts Neuroprotection Through NF-kappaB/c-Rel-dependent Transcription Stroke; a Journal of Cerebral Circulation. Feb, 2009 | Pubmed ID: 19023096 Arterially Perfused Neurosphere-derived Cells Distribute Outside the Ischemic Core in a Model of Transient Focal Ischemia and Reperfusion in Vitro PloS One. 2008 | Pubmed ID: 18648648 Neurosphere-derived Cells Exert a Neuroprotective Action by Changing the Ischemic Microenvironment PloS One. 2007 | Pubmed ID: 17440609 2-Aminotetraline Derivative Protects from Ischemia/reperfusion Brain Injury with a Broad Therapeutic Window Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jun, 2007 | Pubmed ID: 17119539 Selective Inhibition of Plasma Kallikrein Protects Brain from Reperfusion Injury The Journal of Pharmacology and Experimental Therapeutics. Aug, 2006 | Pubmed ID: 16705080 Simvastatin Reduces Caspase-3 Activation and Inflammatory Markers Induced by Hypoxia-ischemia in the Newborn Rat Neurobiology of Disease. Jan, 2006 | Pubmed ID: 16054375 Tumor Necrosis Factor-alpha Inhibits Seizures in Mice Via P75 Receptors Annals of Neurology. Jun, 2005 | Pubmed ID: 15852477 C1-inhibitor Protects Against Brain Ischemia-reperfusion Injury Via Inhibition of Cell Recruitment and Inflammation Neurobiology of Disease. Jun-Jul, 2005 | Pubmed ID: 15837556 The Rai (Shc C) Adaptor Protein Regulates the Neuronal Stress Response and Protects Against Cerebral Ischemia Proceedings of the National Academy of Sciences of the United States of America. Oct, 2004 | Pubmed ID: 15494442 Peripheral Treatment with Enoxaparin, a Low Molecular Weight Heparin, Reduces Plaques and Beta-amyloid Accumulation in a Mouse Model of Alzheimer's Disease The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2004 | Pubmed ID: 15115813 The Powerful Neuroprotective Action of C1-inhibitor on Brain Ischemia-reperfusion Injury Does Not Require C1q The American Journal of Pathology. May, 2004 | Pubmed ID: 15111332 Prophylactic but Not Delayed Administration of Simvastatin Protects Against Long-lasting Cognitive and Morphological Consequences of Neonatal Hypoxic-ischemic Brain Injury, Reduces Interleukin-1beta and Tumor Necrosis Factor-alpha MRNA Induction, and Does Not Affect Endothelial Nitric Oxide Synthase Expression Stroke; a Journal of Cerebral Circulation. Aug, 2003 | Pubmed ID: 12829860 Intracerebroventricular Injection of the Terminal Complement Complex Causes Inflammatory Reaction in the Rat Brain European Journal of Immunology. May, 2003 | Pubmed ID: 12731051 The Inflammatory Response in Cerebral Ischemia: Focus on Cytokines in Stroke Patients Clinical and Experimental Hypertension (New York, N.Y. : 1993). Oct-Nov, 2002 | Pubmed ID: 12450229 Heparin Attenuates Cytotoxic and Inflammatory Activity of Alzheimer Amyloid-beta in Vitro Neurobiology of Aging. Jul-Aug, 2002 | Pubmed ID: 12009502 ניתוח Confocal תלת ממדי של מרקרי Microglia / מקרופאג של קיטוב בניסויי פגיעה מוחית Carlo Perego*1, Stefano Fumagalli*1, Maria-Grazia De Simoni1 1Department of Neuroscience, IRCCS - Istituto di Ricerche Farmacologiche Mario Negri JoVE 50605 Neuroscienze
ניתוח Confocal תלת ממדי של מרקרי Microglia / מקרופאג של קיטוב בניסויי פגיעה מוחית Carlo Perego*1, Stefano Fumagalli*1, Maria-Grazia De Simoni1 1Department of Neuroscience, IRCCS - Istituto di Ricerche Farmacologiche Mario Negri JoVE 50605 Neuroscienze