Mark A. Frye Department of Physiological Science University of California, Los Angeles Biography Publications Institution JoVE Articles Mark A. Frye has not added a biography. If you are Mark A. Frye and would like to personalize this page please email our Author Liaison for assistance. Publications Valproate-induced Hyperammonemic Encephalopathy: an Update on Risk Factors, Clinical Correlates and Management General Hospital Psychiatry. Feb, 2012 | Pubmed ID: 22305367 Review of Pharmacological Treatment in Mood Disorders and Future Directions for Drug Development Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jan, 2012 | Pubmed ID: 21900884 Pharmacogenomics of Antidepressant Induced Mania: a Review and Meta-analysis of the Serotonin Transporter Gene (5HTTLPR) Association Journal of Affective Disorders. Jan, 2012 | Pubmed ID: 21680025 International Consensus Group on Depression Prevention in Bipolar Disorder The Journal of Clinical Psychiatry. Oct, 2011 | Pubmed ID: 22075097 An Olfactory Circuit Increases the Fidelity of Visual Behavior The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2011 | Pubmed ID: 22016537 Trazodone and Alcohol Relapse: a Retrospective Study Following Residential Treatment The American Journal on Addictions / American Academy of Psychiatrists in Alcoholism and Addictions. Nov-Dec, 2011 | Pubmed ID: 21999497 Differences in Demographic Composition and in Work, Social, and Functional Limitations Among the Populations with Unipolar Depression and Bipolar Disorder: Results from a Nationally Representative Sample Health and Quality of Life Outcomes. 2011 | Pubmed ID: 21995725 Direct Costs of Bipolar Disorder Versus Other Chronic Conditions: an Employer-based Health Plan Analysis Psychiatric Services (Washington, D.C.). Sep, 2011 | Pubmed ID: 21885587 Odor Identity Influences Tracking of Temporally Patterned Plumes in Drosophila BMC Neuroscience. 2011 | Pubmed ID: 21708035 Voltage-dependent Mania After Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: a Case Report Biological Psychiatry. Jul, 2011 | Pubmed ID: 21414603 Clinical Practice. Bipolar Disorder--a Focus on Depression The New England Journal of Medicine. Jan, 2011 | Pubmed ID: 21208108 Differential Clinical Characteristics, Medication Usage, and Treatment Response of Bipolar Disorder in the US Versus The Netherlands and Germany International Clinical Psychopharmacology. Mar, 2011 | Pubmed ID: 21178634 Utilization of Residential Alcoholism Treatment in Bipolar Disorder The American Journal on Addictions / American Academy of Psychiatrists in Alcoholism and Addictions. Jan-Feb, 2011 | Pubmed ID: 21175919 Prevalence and Correlates of Eating Disorders in 875 Patients with Bipolar Disorder Journal of Affective Disorders. Feb, 2011 | Pubmed ID: 20674033 Complexity of Pharmacologic Treatment Required for Sustained Improvement in Outpatients with Bipolar Disorder The Journal of Clinical Psychiatry. Sep, 2010 | Pubmed ID: 20923622 Theta Motion Processing in Fruit Flies Frontiers in Behavioral Neuroscience. 2010 | Pubmed ID: 20700393 Adjunctive Armodafinil for Major Depressive Episodes Associated with Bipolar I Disorder: a Randomized, Multicenter, Double-blind, Placebo-controlled, Proof-of-concept Study The Journal of Clinical Psychiatry. Oct, 2010 | Pubmed ID: 20673554 Early-onset Bipolar Disorder and Treatment Delay Are Risk Factors for Poor Outcome in Adulthood The Journal of Clinical Psychiatry. Jul, 2010 | Pubmed ID: 20667291 Gender Differences in the Relationship Between Depressive Symptoms and Cravings in Alcoholism The American Journal on Addictions / American Academy of Psychiatrists in Alcoholism and Addictions. Jul-Aug, 2010 | Pubmed ID: 20653643 Multisensory Integration for Odor Tracking by Flying Drosophila: Behavior, Circuits and Speculation Communicative & Integrative Biology. Jan, 2010 | Pubmed ID: 20539786 Improving the Design of Maintenance Studies for Bipolar Disorder Current Medical Research and Opinion. Aug, 2010 | Pubmed ID: 20515320 Mutation of the Drosophila Vesicular GABA Transporter Disrupts Visual Figure Detection The Journal of Experimental Biology. May, 2010 | Pubmed ID: 20435823 Mechanisms of Odor-tracking: Multiple Sensors for Enhanced Perception and Behavior Frontiers in Cellular Neuroscience. 2010 | Pubmed ID: 20407585 Dynamics of Optomotor Responses in Drosophila to Perturbations in Optic Flow The Journal of Experimental Biology. Apr, 2010 | Pubmed ID: 20348349 Gender and Depressive Symptoms in 711 Patients with Bipolar Disorder Evaluated Prospectively in the Stanley Foundation Bipolar Treatment Outcome Network The American Journal of Psychiatry. Jun, 2010 | Pubmed ID: 20231325 Multisensory Systems Integration for High-performance Motor Control in Flies Current Opinion in Neurobiology. Jun, 2010 | Pubmed ID: 20202821 Modafinil for Bipolar Depression with Comorbid Methamphetamine Abuse The American Journal on Addictions / American Academy of Psychiatrists in Alcoholism and Addictions. Mar-Apr, 2010 | Pubmed ID: 20163392 Visual Stabilization Dynamics Are Enhanced by Standing Flight Velocity Biology Letters. Jun, 2010 | Pubmed ID: 19955168 Neurobiology: Fly Gyro-vision Current Biology : CB. Dec, 2009 | Pubmed ID: 20064422 Olanzapine/fluoxetine Combination for the Treatment of Mixed Depression in Bipolar I Disorder: a Post Hoc Analysis The Journal of Clinical Psychiatry. Oct, 2009 | Pubmed ID: 19906346 Mood Stabilization and Destabilization During Acute and Continuation Phase Treatment for Bipolar I Disorder with Lamotrigine or Placebo The Journal of Clinical Psychiatry. Sep, 2009 | Pubmed ID: 19689918 Flies Require Bilateral Sensory Input to Track Odor Gradients in Flight Current Biology : CB. Aug, 2009 | Pubmed ID: 19576769 Disrupting Disordered Neurocircuitry: Treating Refractory Psychiatric Illness with Neuromodulation Mayo Clinic Proceedings. Mayo Clinic. Jun, 2009 | Pubmed ID: 19483169 Impact of Antidepressant Continuation After Acute Positive or Partial Treatment Response for Bipolar Depression: a Blinded, Randomized Study The Journal of Clinical Psychiatry. Apr, 2009 | Pubmed ID: 19358785 Peripheral Visual Circuits Functionally Segregate Motion and Phototaxis Behaviors in the Fly Current Biology : CB. Apr, 2009 | Pubmed ID: 19303299 Invertebrate Solutions for Sensing Gravity Current Biology : CB. Mar, 2009 | Pubmed ID: 19278626 The Neuro-ecology of Resource Localization in Drosophila: Behavioral Components of Perception and Search Fly. Jan-Mar, 2009 | Pubmed ID: 19218831 The Psychometric Validation of the Sheehan Disability Scale (SDS) in Patients with Bipolar Disorder Psychiatry Research. Jan, 2009 | Pubmed ID: 19042030 Correlates of Treatment-emergent Mania Associated with Antidepressant Treatment in Bipolar Depression The American Journal of Psychiatry. Feb, 2009 | Pubmed ID: 19015231 Diagnostic Dilemmas and Clinical Correlates of Mixed States in Bipolar Disorder The Journal of Clinical Psychiatry. May, 2008 | Pubmed ID: 18681758 Context-dependent Olfactory Enhancement of Optomotor Flight Control in Drosophila The Journal of Experimental Biology. Aug, 2008 | Pubmed ID: 18626082 Flies See Second-order Motion Current Biology : CB. Jun, 2008 | Pubmed ID: 18522814 Aripiprazole Efficacy in Irritability and Disruptive-aggressive Symptoms: Young Mania Rating Scale Line Analysis from Two, Randomized, Double-blind, Placebo-controlled Trials Journal of Clinical Psychopharmacology. Apr, 2008 | Pubmed ID: 18344741 Are Bipolar Mood Symptoms Affected by the Phase of the Menstrual Cycle? Journal of Women's Health (2002). Apr, 2008 | Pubmed ID: 18328012 Animal Behavior: Flying Back to Front Current Biology : CB. Feb, 2008 | Pubmed ID: 18302921 Crossmodal Visual Input for Odor Tracking During Fly Flight Current Biology : CB. Feb, 2008 | Pubmed ID: 18280156 Incidence of Childhood-onset Bipolar Illness in the USA and Europe The British Journal of Psychiatry : the Journal of Mental Science. Feb, 2008 | Pubmed ID: 18245035 Modal Subcomponents of Metabolic Syndrome in Patients with Bipolar Disorder Journal of Affective Disorders. Feb, 2008 | Pubmed ID: 17628693 Six-month Prospective Life Charting of Mood Symptoms with Lamotrigine Monotherapy Versus Placebo in Rapid Cycling Bipolar Disorder Biological Psychiatry. Jan, 2008 | Pubmed ID: 17543894 Increased Suicidality in Mania Complicated by Alcoholism Psychiatry (Edgmont (Pa. : Township)). Apr, 2007 | Pubmed ID: 20711326 Visual Edge Orientation Shapes Free-flight Behavior in Drosophila Fly. May-Jun, 2007 | Pubmed ID: 18820449 Defining the Clinical Course of Bipolar Disorder: Response, Remission, Relapse, Recurrence, and Roughening Psychopharmacology Bulletin. 2007 | Pubmed ID: 18007564 Bipolar Depression: Best Practices for the Hospitalized Patient CNS Spectrums. Nov, 2007 | Pubmed ID: 17984859 Quetiapine for the Continuation Treatment of Bipolar Depression: Naturalistic Prospective Case Series from the Stanley Bipolar Treatment Network International Clinical Psychopharmacology. Nov, 2007 | Pubmed ID: 17917557 The Spatial, Temporal and Contrast Properties of Expansion and Rotation Flight Optomotor Responses in Drosophila The Journal of Experimental Biology. Sep, 2007 | Pubmed ID: 17766299 Comorbid Substance Use Disorder in Women with Bipolar Disorder Associated with Criminal Arrest Bipolar Disorders. Aug, 2007 | Pubmed ID: 17680926 Three Times More Days Depressed Than Manic or Hypomanic in Both Bipolar I and Bipolar II Disorder Bipolar Disorders. Aug, 2007 | Pubmed ID: 17680925 A Placebo-controlled Evaluation of Adjunctive Modafinil in the Treatment of Bipolar Depression The American Journal of Psychiatry. Aug, 2007 | Pubmed ID: 17671288 Lack of Mania Prophylaxis Associated with Lamotrigine Monotherapy in Manic-predominant Bipolar I Disorder The Journal of Clinical Psychiatry. Jun, 2007 | Pubmed ID: 17592931 A 24-week, Randomized, Controlled Trial of Adjunctive Sibutramine Versus Topiramate in the Treatment of Weight Gain in Overweight or Obese Patients with Bipolar Disorders Bipolar Disorders. Jun, 2007 | Pubmed ID: 17547588 The Poor Prognosis of Childhood-onset Bipolar Disorder The Journal of Pediatrics. May, 2007 | Pubmed ID: 17452221 Increased Anterior Cingulate/medial Prefrontal Cortical Glutamate and Creatine in Bipolar Depression Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Dec, 2007 | Pubmed ID: 17429412 Free-flight Odor Tracking in Drosophila is Consistent with an Optimal Intermittent Scale-free Search PloS One. 2007 | Pubmed ID: 17406678 Reduced Concentrations of N-acetylaspartate (NAA) and the NAA-creatine Ratio in the Basal Ganglia in Bipolar Disorder: a Study Using 3-Tesla Proton Magnetic Resonance Spectroscopy Psychiatry Research. Apr, 2007 | Pubmed ID: 17346949 Behavioral Neurobiology: a Vibrating Gyroscope Controls Fly Steering Maneuvers Current Biology : CB. Feb, 2007 | Pubmed ID: 17307048 Alcoholism and Anxiety in Bipolar Illness: Differential Lifetime Anxiety Comorbidity in Bipolar I Women with and Without Alcoholism Journal of Affective Disorders. Aug, 2007 | Pubmed ID: 17254638 Open-label Aripiprazole in the Treatment of Acute Bipolar Depression: a Prospective Pilot Trial Journal of Affective Disorders. Aug, 2007 | Pubmed ID: 17229469 Free T4 Index and Clinical Outcome in Patients with Depression Journal of Affective Disorders. Jun, 2007 | Pubmed ID: 17123630 Low Cerebrospinal Fluid Glutamate and Glycine in Refractory Affective Disorder Biological Psychiatry. Jan, 2007 | Pubmed ID: 16735030 Predictors of Bipolar Disorder Risk Among Patients Currently Treated for Major Depression MedGenMed : Medscape General Medicine. 2006 | Pubmed ID: 17406171 Incidence and Time Course of Subsyndromal Symptoms in Patients with Bipolar I Disorder: an Evaluation of 2 Placebo-controlled Maintenance Trials The Journal of Clinical Psychiatry. Nov, 2006 | Pubmed ID: 17196051 New Findings from the Bipolar Collaborative Network: Clinical Implications for Therapeutics Current Psychiatry Reports. Dec, 2006 | Pubmed ID: 17162830 Bipolar Disorder and Comorbid Alcoholism: Prevalence Rate and Treatment Considerations Bipolar Disorders. Dec, 2006 | Pubmed ID: 17156154 Subsyndromal Depressive Symptoms Are Associated with Functional Impairment in Patients with Bipolar Disorder: Results of a Large, Multisite Study The Journal of Clinical Psychiatry. Oct, 2006 | Pubmed ID: 17107246 Healthcare Resource Utilization in Bipolar Depression Compared with Unipolar Depression: Results of a United States Population-based Study CNS Spectrums. Sep, 2006 | Pubmed ID: 16946695 Discharge Against Medical Advice from Inpatient Psychiatric Treatment: a Literature Review Psychiatric Services (Washington, D.C.). Aug, 2006 | Pubmed ID: 16870972 Double-blind, Randomized, Placebo-controlled Trials of Ethyl-eicosapentanoate in the Treatment of Bipolar Depression and Rapid Cycling Bipolar Disorder Biological Psychiatry. Nov, 2006 | Pubmed ID: 16814257 Lower Switch Rate in Depressed Patients with Bipolar II Than Bipolar I Disorder Treated Adjunctively with Second-generation Antidepressants The American Journal of Psychiatry. Feb, 2006 | Pubmed ID: 16449487 Risk of Switch in Mood Polarity to Hypomania or Mania in Patients with Bipolar Depression During Acute and Continuation Trials of Venlafaxine, Sertraline, and Bupropion As Adjuncts to Mood Stabilizers The American Journal of Psychiatry. Feb, 2006 | Pubmed ID: 16449476 Use of Health Care Services Among Persons Who Screen Positive for Bipolar Disorder Psychiatric Services (Washington, D.C.). Dec, 2005 | Pubmed ID: 16339614 Clinical and Legal Characteristics of Inmates with Bipolar Disorder Current Psychiatry Reports. Dec, 2005 | Pubmed ID: 16318827 Mixed Hypomania in 908 Patients with Bipolar Disorder Evaluated Prospectively in the Stanley Foundation Bipolar Treatment Network: a Sex-specific Phenomenon Archives of General Psychiatry. Oct, 2005 | Pubmed ID: 16203954 Longitudinal Evaluation of Reproductive Function in Women Treated for Bipolar Disorder Journal of Affective Disorders. Dec, 2005 | Pubmed ID: 16171873 Patterns of Alcohol Consumption in Bipolar Patients Comorbid for Alcohol Abuse or Dependence Bipolar Disorders. Aug, 2005 | Pubmed ID: 16026491 Relationship Between Criminal Arrest and Community Treatment History Among Patients with Bipolar Disorder Psychiatric Services (Washington, D.C.). Jul, 2005 | Pubmed ID: 16020818 Comparison of Rapid-cycling and Non-rapid-cycling Bipolar Disorder Based on Prospective Mood Ratings in 539 Outpatients The American Journal of Psychiatry. Jul, 2005 | Pubmed ID: 15994709 Reproductive Function and Risk for PCOS in Women Treated for Bipolar Disorder Bipolar Disorders. Jun, 2005 | Pubmed ID: 15898962 Open-label Adjunctive Zonisamide in the Treatment of Bipolar Disorders: a Prospective Trial The Journal of Clinical Psychiatry. May, 2005 | Pubmed ID: 15889949 Preliminary Observations on the Effectiveness of Levetiracetam in the Open Adjunctive Treatment of Refractory Bipolar Disorder The Journal of Clinical Psychiatry. Mar, 2005 | Pubmed ID: 15766304 Closing the Loop Between Neurobiology and Flight Behavior in Drosophila Current Opinion in Neurobiology. Dec, 2004 | Pubmed ID: 15582376 Impact of Depressive Symptoms Compared with Manic Symptoms in Bipolar Disorder: Results of a U.S. Community-based Sample The Journal of Clinical Psychiatry. Nov, 2004 | Pubmed ID: 15554762 Peripheral Thyroid Hormones and Response to Selective Serotonin Reuptake Inhibitors Journal of Psychiatry & Neuroscience : JPN. Sep, 2004 | Pubmed ID: 15486607 Chart Review of the Impact of Attention-deficit/hyperactivity Disorder Comorbidity on Response to Lithium or Divalproex Sodium in Adolescent Mania The Journal of Clinical Psychiatry. Aug, 2004 | Pubmed ID: 15323589 Correlates of 1-year Prospective Outcome in Bipolar Disorder: Results from the Stanley Foundation Bipolar Network The American Journal of Psychiatry. Aug, 2004 | Pubmed ID: 15285972 Unmet Needs in Bipolar Depression Depression and Anxiety. 2004 | Pubmed ID: 15274168 Clinical and Legal Correlates of Inmates with Bipolar Disorder at Time of Criminal Arrest The Journal of Clinical Psychiatry. Feb, 2004 | Pubmed ID: 15003073 Motor Output Reflects the Linear Superposition of Visual and Olfactory Inputs in Drosophila The Journal of Experimental Biology. Jan, 2004 | Pubmed ID: 14638839 Spatial Organization of Visuomotor Reflexes in Drosophila The Journal of Experimental Biology. Jan, 2004 | Pubmed ID: 14638838 A Re-evaluation of the Role of Antidepressants in the Treatment of Bipolar Depression: Data from the Stanley Foundation Bipolar Network Bipolar Disorders. Dec, 2003 | Pubmed ID: 14636363 An Overview of Recent Findings of the Stanley Foundation Bipolar Network (Part I) Bipolar Disorders. Oct, 2003 | Pubmed ID: 14525551 Psychosis in Bipolar Disorder: Phenomenology and Impact on Morbidity and Course of Illness Comprehensive Psychiatry. Jul-Aug, 2003 | Pubmed ID: 12923703 Impact of Antidepressant Discontinuation After Acute Bipolar Depression Remission on Rates of Depressive Relapse at 1-year Follow-up The American Journal of Psychiatry. Jul, 2003 | Pubmed ID: 12832239 Morbidity in 258 Bipolar Outpatients Followed for 1 Year with Daily Prospective Ratings on the NIMH Life Chart Method The Journal of Clinical Psychiatry. Jun, 2003 | Pubmed ID: 12823083 A Signature of Salience in the Drosophila Brain Nature Neuroscience. Jun, 2003 | Pubmed ID: 12771957 Factors Associated with Suicide Attempts in 648 Patients with Bipolar Disorder in the Stanley Foundation Bipolar Network The Journal of Clinical Psychiatry. May, 2003 | Pubmed ID: 12755652 Gender Differences in Prevalence, Risk, and Clinical Correlates of Alcoholism Comorbidity in Bipolar Disorder The American Journal of Psychiatry. May, 2003 | Pubmed ID: 12727691 Impact of Bipolar Disorder on a U.S. Community Sample The Journal of Clinical Psychiatry. Apr, 2003 | Pubmed ID: 12716245 Acceleration and Augmentation Strategies for Treating Bipolar Depression Biological Psychiatry. Apr, 2003 | Pubmed ID: 12706955 Treating Acute Mania The Journal of Family Practice. Mar, 2003 | Pubmed ID: 12676078 Screening for Bipolar Disorder in the Community The Journal of Clinical Psychiatry. Jan, 2003 | Pubmed ID: 12590624 Odor Localization Requires Visual Feedback During Free Flight in Drosophila Melanogaster The Journal of Experimental Biology. Mar, 2003 | Pubmed ID: 12547939 Low CSF Somatostatin Associated with Response to Nimodipine in Patents with Affective Illness Biological Psychiatry. Jan, 2003 | Pubmed ID: 12547475 Validity of the Mood Disorder Questionnaire: a General Population Study The American Journal of Psychiatry. Jan, 2003 | Pubmed ID: 12505821 Acute Antimanic Efficacy and Safety of Oxcarbazepine in an Open Trial with an On-off-on Design Bipolar Disorders. Dec, 2002 | Pubmed ID: 12519102 Tiagabine in Treatment Refractory Bipolar Disorder: a Clinical Case Series Bipolar Disorders. Oct, 2002 | Pubmed ID: 12479659 Rash in Multicenter Trials of Lamotrigine in Mood Disorders: Clinical Relevance and Management The Journal of Clinical Psychiatry. Nov, 2002 | Pubmed ID: 12444815 Subsyndromal Depression is Associated with Functional Impairment in Patients with Bipolar Disorder The Journal of Clinical Psychiatry. Sep, 2002 | Pubmed ID: 12363122 Synaptic, Intracellular, and Neuroprotective Mechanisms of Anticonvulsants: Are They Relevant for the Treatment and Course of Bipolar Disorders? Journal of Affective Disorders. May, 2002 | Pubmed ID: 12103447 Mania and Attention Deficit Hyperactivity Disorder in a Prepubertal Child: Diagnostic and Treatment Challenges The American Journal of Psychiatry. Jun, 2002 | Pubmed ID: 12042177 High Rate of Autoimmune Thyroiditis in Bipolar Disorder: Lack of Association with Lithium Exposure Biological Psychiatry. Feb, 2002 | Pubmed ID: 11958781 Early Physical and Sexual Abuse Associated with an Adverse Course of Bipolar Illness Biological Psychiatry. Feb, 2002 | Pubmed ID: 11958779 Correlates of Overweight and Obesity in 644 Patients with Bipolar Disorder The Journal of Clinical Psychiatry. Mar, 2002 | Pubmed ID: 11926719 Principal Components of the Beck Depression Inventory and Regional Cerebral Metabolism in Unipolar and Bipolar Depression Biological Psychiatry. Mar, 2002 | Pubmed ID: 11904133 Clinical Predictors of Response to Lamotrigine and Gabapentin Monotherapy in Refractory Affective Disorders Biological Psychiatry. Feb, 2002 | Pubmed ID: 11839368 Visually Mediated Odor Tracking During Flight in Drosophila Mark A. Frye1, Brian J. Duistermars1 1Department of Physiological Science, University of California, Los Angeles JoVE 1110 Biologia A Magnetic Tether System to Investigate Visual and Olfactory Mediated Flight Control in Drosophila Brian J. Duistermars1, Mark A. Frye1 1Department of Physiological Science, University of California, Los Angeles JoVE 1063 Biologia
Visually Mediated Odor Tracking During Flight in Drosophila Mark A. Frye1, Brian J. Duistermars1 1Department of Physiological Science, University of California, Los Angeles JoVE 1110 Biologia
A Magnetic Tether System to Investigate Visual and Olfactory Mediated Flight Control in Drosophila Brian J. Duistermars1, Mark A. Frye1 1Department of Physiological Science, University of California, Los Angeles JoVE 1063 Biologia