Mark D. Zabel Prion Research Center Colorado State University Biography Publications Institution JoVE Articles Mark D. Zabel has not added a biography. If you are Mark D. Zabel and would like to personalize this page please email our Author Liaison for assistance. Publications Intranasally Delivered Mesenchymal Stromal Cells Decrease Glial Inflammation Early in Prion Disease Frontiers in Neuroscience. 2023 | Pubmed ID: 37250395 A Multiplexed, Paired-pooled Droplet Digital PCR Assay for Detection of SARS-CoV-2 in Saliva Scientific Reports. Feb, 2023 | Pubmed ID: 36813822 Adipose-derived Mesenchymal Stromal Cells Decrease Prion-induced Glial Inflammation in Vitro Scientific Reports. Dec, 2022 | Pubmed ID: 36581683 Tissue-specific Biochemical Differences Between Chronic Wasting Disease Prions Isolated from Free-ranging White-tailed Deer (Odocoileus Virginianus) The Journal of Biological Chemistry. Apr, 2022 | Pubmed ID: 35304100 SiRNA Therapeutics for Protein Misfolding Diseases of the Central Nervous System Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 33928585 Chronic Wasting Disease in Cervids: Implications for Prion Transmission to Humans and Other Animal Species MBio. Jul, 2019 | Pubmed ID: 31337719 Lipopeptide Delivery of SiRNA to the Central Nervous System Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30838631 Relative Impact of Complement Receptors CD21/35 (Cr2/1) on Scrapie Pathogenesis in Mice MSphere. 2017 | Pubmed ID: 29202042 Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis Journal of Immunology (Baltimore, Md. : 1950). Dec, 2017 | Pubmed ID: 29070671 Pathways of Prion Spread During Early Chronic Wasting Disease in Deer Journal of Virology. May, 2017 | Pubmed ID: 28250130 Endogenous Brain Lipids Inhibit Prion Amyloid Formation Journal of Virology. May, 2017 | Pubmed ID: 28202758 Generation of a Unique Cervid Prion Strain Using Protein Misfolding Cyclic Amplification MSphere. 2017 | Pubmed ID: 28144628 Clay Components in Soil Dictate Environmental Stability and Bioavailability of Cervid Prions in Mice Frontiers in Microbiology. 2016 | Pubmed ID: 27933048 Dietary Magnesium and Copper Affect Survival Time and Neuroinflammation in Chronic Wasting Disease Prion. May, 2016 | Pubmed ID: 27216881 Detection and Quantification of CWD Prions in Fixed Paraffin Embedded Tissues by Real-Time Quaking-Induced Conversion Scientific Reports. 2016 | Pubmed ID: 27157060 A Brief History of Prions Pathogens and Disease. Dec, 2015 | Pubmed ID: 26449713 Prions--not Your Immunologist's Pathogen PLoS Pathogens. Feb, 2015 | Pubmed ID: 25695738 Amyloid-β and Proinflammatory Cytokines Utilize a Prion Protein-dependent Pathway to Activate NADPH Oxidase and Induce Cofilin-actin Rods in Hippocampal Neurons PloS One. 2014 | Pubmed ID: 24760020 Complement Protein C3 Exacerbates Prion Disease in a Mouse Model of Chronic Wasting Disease International Immunology. Dec, 2013 | Pubmed ID: 24038599 Intranasal Inoculation of White-tailed Deer (Odocoileus Virginianus) with Lyophilized Chronic Wasting Disease Prion Particulate Complexed to Montmorillonite Clay PloS One. 2013 | Pubmed ID: 23671598 Estimating Prion Adsorption Capacity of Soil by BioAssay of Subtracted Infectivity from Complex Solutions (BASICS) PloS One. 2013 | Pubmed ID: 23484043 Lipopeptide Delivery of SiRNA to the Central Nervous System Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23070775 Genetic Depletion of Complement Receptors CD21/35 Prevents Terminal Prion Disease in a Mouse Model of Chronic Wasting Disease Journal of Immunology (Baltimore, Md. : 1950). Nov, 2012 | Pubmed ID: 23002439 Incunabular Immunological Events in Prion Trafficking Scientific Reports. 2012 | Pubmed ID: 22679554 Detection of Prion Protein in the Cerebrospinal Fluid of Elk (Cervus Canadensis Nelsoni) with Chronic Wasting Disease Using Protein Misfolding Cyclic Amplification Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. Jul, 2012 | Pubmed ID: 22621952 Detection of PrPCWD in Feces from Naturally Exposed Rocky Mountain Elk (Cervus Elaphus Nelsoni) Using Protein Misfolding Cyclic Amplification Journal of Wildlife Diseases. Apr, 2012 | Pubmed ID: 22493117 Sensitivity of Protein Misfolding Cyclic Amplification Versus Immunohistochemistry in Ante-mortem Detection of Chronic Wasting Disease The Journal of General Virology. May, 2012 | Pubmed ID: 22278825 Liposome-siRNA-peptide Complexes Cross the Blood-brain Barrier and Significantly Decrease PrP on Neuronal Cells and PrP in Infected Cell Cultures PloS One. 2010 | Pubmed ID: 20559428 Detection of Sub-clinical CWD Infection in Conventional Test-negative Deer Long After Oral Exposure to Urine and Feces from CWD+ Deer PloS One. 2009 | Pubmed ID: 19956732 Detection of Protease-resistant Cervid Prion Protein in Water from a CWD-endemic Area Prion. Jul-Sep, 2009 | Pubmed ID: 19823039 CCR2+Ly-6Chi Monocytes Are Crucial for the Effector Phase of Autoimmunity in the Central Nervous System Brain : a Journal of Neurology. Sep, 2009 | Pubmed ID: 19531531 Detection of CWD Prions in Urine and Saliva of Deer by Transgenic Mouse Bioassay PloS One. 2009 | Pubmed ID: 19293928 Trans-species Amplification of PrP(CWD) and Correlation with Rigid Loop 170N Virology. Apr, 2009 | Pubmed ID: 19269662 In Vitro Strain Adaptation of CWD Prions by Serial Protein Misfolding Cyclic Amplification Virology. Dec, 2008 | Pubmed ID: 18952250 Stromal Complement Receptor CD21/35 Facilitates Lymphoid Prion Colonization and Pathogenesis Journal of Immunology (Baltimore, Md. : 1950). Nov, 2007 | Pubmed ID: 17947689 Efficient in Vitro Amplification of Chronic Wasting Disease PrPRES Journal of Virology. Sep, 2007 | Pubmed ID: 17553879 Complement Receptors CD21/35 Link Innate and Protective Immunity During Streptococcus Pneumoniae Infection by Regulating IgG3 Antibody Responses Immunity. Dec, 2002 | Pubmed ID: 12479818 Yin Yang 1, Oct1, and NFAT-4 Form Repeating, Cyclosporin-sensitive Regulatory Modules Within the Murine CD21 Intronic Control Region Journal of Immunology (Baltimore, Md. : 1950). Apr, 2002 | Pubmed ID: 11907091 Depletion of Lyn Kinase from the BCR Complex and Inhibition of B Cell Activation by Excess CD21 Ligation International Immunology. Feb, 2002 | Pubmed ID: 11809733 Author Spotlight: Insight Into Advances in Prion Diseases Research Arielle J. D. Hay1,2, Katriana A. Popichak1,2, Mark D. Zabel1,2, Julie A. Moreno1,3 1Prion Research Center, Colorado State University, 2Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 3Department of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University JoVE 65565 Neuroscienze Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes Heather R. Bender1, Sarah Kane1, Mark D. Zabel1 1Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University JoVE 54106 Bioingegneria Monitoring Immune Cells Trafficking Fluorescent Prion Rods Hours after Intraperitoneal Infection Theodore E. Johnson*1, Brady A. Michel*1, Crystal Meyerett1, Angela Duffy1, Anne Avery1, Steven Dow1, Mark D. Zabel1 1Department of Microbiology, Immunology and Pathology, Colorado State University JoVE 2349 Immunologia e infezioni
Author Spotlight: Insight Into Advances in Prion Diseases Research Arielle J. D. Hay1,2, Katriana A. Popichak1,2, Mark D. Zabel1,2, Julie A. Moreno1,3 1Prion Research Center, Colorado State University, 2Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 3Department of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University JoVE 65565 Neuroscienze
Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes Heather R. Bender1, Sarah Kane1, Mark D. Zabel1 1Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University JoVE 54106 Bioingegneria
Monitoring Immune Cells Trafficking Fluorescent Prion Rods Hours after Intraperitoneal Infection Theodore E. Johnson*1, Brady A. Michel*1, Crystal Meyerett1, Angela Duffy1, Anne Avery1, Steven Dow1, Mark D. Zabel1 1Department of Microbiology, Immunology and Pathology, Colorado State University JoVE 2349 Immunologia e infezioni