Matthias Heinemann Molecular Systems Biology, Groningen Biomolecular Sciences and Biotechnology Institute University of Groningen Biography Publications Institution JoVE Articles Matthias Heinemann has not added a biography. If you are Matthias Heinemann and would like to personalize this page please email our Author Liaison for assistance. Publications Mass Spectrometry-based Metabolomics of Single Yeast Cells Proceedings of the National Academy of Sciences of the United States of America. May, 2013 | Pubmed ID: 23671112 Construction and Use of a Microfluidic Dissection Platform for Long-term Imaging of Cellular Processes in Budding Yeast Nature Protocols. Jun, 2013 | Pubmed ID: 23640166 Dissecting Specific and Global Transcriptional Regulation of Bacterial Gene Expression Molecular Systems Biology. 2013 | Pubmed ID: 23591774 Temporal System-level Organization of the Switch from Glycolytic to Gluconeogenic Operation in Yeast Molecular Systems Biology. 2013 | Pubmed ID: 23549479 Functioning of a Metabolic Flux Sensor in Escherichia Coli Proceedings of the National Academy of Sciences of the United States of America. Jan, 2013 | Pubmed ID: 23277571 Prediction of Microbial Growth Rate Versus Biomass Yield by a Metabolic Network with Kinetic Parameters PLoS Computational Biology. 2012 | Pubmed ID: 22792053 Multidimensional Optimality of Microbial Metabolism Science (New York, N.Y.). May, 2012 | Pubmed ID: 22556256 Whole Lifespan Microscopic Observation of Budding Yeast Aging Through a Microfluidic Dissection Platform Proceedings of the National Academy of Sciences of the United States of America. Mar, 2012 | Pubmed ID: 22421136 System-level Insights into Yeast Metabolism by Thermodynamic Analysis of Elementary Flux Modes PLoS Computational Biology. 2012 | Pubmed ID: 22416224 A Flux-sensing Mechanism Could Regulate the Switch Between Respiration and Fermentation FEMS Yeast Research. Mar, 2012 | Pubmed ID: 22129078 Carbon-13 Labelling Strategy for Studying the ATP Metabolism in Individual Yeast Cells by Micro-arrays for Mass Spectrometry Molecular BioSystems. Oct, 2011 | Pubmed ID: 21850345 Condition-dependent Cell Volume and Concentration of Escherichia Coli to Facilitate Data Conversion for Systems Biology Modeling PloS One. 2011 | Pubmed ID: 21829590 The Cost of Virulence: Retarded Growth of Salmonella Typhimurium Cells Expressing Type III Secretion System 1 PLoS Pathogens. Jul, 2011 | Pubmed ID: 21829349 Optimization of a Blueprint for in Vitro Glycolysis by Metabolic Real-time Analysis Nature Chemical Biology. May, 2011 | Pubmed ID: 21423171 Comprehensive Quantitative Analysis of Central Carbon and Amino-acid Metabolism in Saccharomyces Cerevisiae Under Multiple Conditions by Targeted Proteomics Molecular Systems Biology. Feb, 2011 | Pubmed ID: 21283140 From Good Old Biochemical Analyses to High-throughput Omics Measurements and Back Current Opinion in Biotechnology. Feb, 2011 | Pubmed ID: 21190838 Single Cell Metabolomics Current Opinion in Biotechnology. Feb, 2011 | Pubmed ID: 20934866 Thermodynamic Calculations for Biochemical Transport and Reaction Processes in Metabolic Networks Biophysical Journal. Nov, 2010 | Pubmed ID: 21081060 Systems Biology of Microbial Metabolism Current Opinion in Microbiology. Jun, 2010 | Pubmed ID: 20219420 Bacterial Adaptation Through Distributed Sensing of Metabolic Fluxes Molecular Systems Biology. 2010 | Pubmed ID: 20212527 Differential Glucose Repression in Common Yeast Strains in Response to HXK2 Deletion FEMS Yeast Research. May, 2010 | Pubmed ID: 20199578 Exploiting Cell-free Systems: Implementation and Debugging of a System of Biotransformations Biotechnology and Bioengineering. Jun, 2010 | Pubmed ID: 20091765 Nutritional Systems Biology Modeling: from Molecular Mechanisms to Physiology PLoS Computational Biology. Nov, 2009 | Pubmed ID: 19956660 Physiology of Mycobacteria Advances in Microbial Physiology. 2009 | Pubmed ID: 19573696 A Divide-and-conquer Approach to Analyze Underdetermined Biochemical Models Bioinformatics (Oxford, England). Feb, 2009 | Pubmed ID: 19126574 A Consensus Yeast Metabolic Network Reconstruction Obtained from a Community Approach to Systems Biology Nature Biotechnology. Oct, 2008 | Pubmed ID: 18846089 Mass Spectrometric Method for Analyzing Metabolites in Yeast with Single Cell Sensitivity Angewandte Chemie (International Ed. in English). 2008 | Pubmed ID: 18543269 AnNET: a Tool for Network-embedded Thermodynamic Analysis of Quantitative Metabolome Data BMC Bioinformatics. 2008 | Pubmed ID: 18416814 Living with an Imperfect Cell Wall: Compensation of FemAB Inactivation in Staphylococcus Aureus BMC Genomics. 2007 | Pubmed ID: 17784943 Genetics. Getting Closer to the Whole Picture Science (New York, N.Y.). Apr, 2007 | Pubmed ID: 17463274 Characterization of the AlkS/P(alkB)-expression System As an Efficient Tool for the Production of Recombinant Proteins in Escherichia Coli Fed-batch Fermentations Biotechnology and Bioengineering. Feb, 2007 | Pubmed ID: 16865736 Systematic Assignment of Thermodynamic Constraints in Metabolic Network Models BMC Bioinformatics. 2006 | Pubmed ID: 17123434 Reporter Metabolite Analysis of Transcriptional Profiles of a Staphylococcus Aureus Strain with Normal Phenotype and Its Isogenic HemB Mutant Displaying the Small-colony-variant Phenotype Journal of Bacteriology. Nov, 2006 | Pubmed ID: 16980462 Synthetic Biology--putting Engineering into Biology Bioinformatics (Oxford, England). Nov, 2006 | Pubmed ID: 16954140 Putative Regulatory Sites Unraveled by Network-embedded Thermodynamic Analysis of Metabolome Data Molecular Systems Biology. 2006 | Pubmed ID: 16788595 Integrated Operation of Continuous Chromatography and Biotransformations for the Generic High Yield Production of Fine Chemicals Journal of Biotechnology. Jun, 2006 | Pubmed ID: 16516996 Suitability of Teicoplanin-aglycone Bonded Stationary Phase for Simulated Moving Bed Enantioseparation of Racemic Amino Acids Employing Composition-constrained Eluents Journal of Chromatography. A. Apr, 2006 | Pubmed ID: 16500665 Optimization of Adsorptive Immobilization of Alcohol Dehydrogenases Journal of Bioscience and Bioengineering. Apr, 2005 | Pubmed ID: 16233799 In Silico Genome-scale Reconstruction and Validation of the Staphylococcus Aureus Metabolic Network Biotechnology and Bioengineering. Dec, 2005 | Pubmed ID: 16155945 Method for Quantitative Determination of Spatial Polymer Distribution in Alginate Beads Using Raman Spectroscopy Applied Spectroscopy. Mar, 2005 | Pubmed ID: 15901307 Optimization of Enzymatic Gas-phase Reactions by Increasing the Long-term Stability of the Catalyst Biotechnology Progress. May-Jun, 2004 | Pubmed ID: 15176907 New Insights in the Spatially Resolved Dynamic PH Measurement in Macroscopic Large Absorbent Particles by Confocal Laser Scanning Microscopy Journal of Chromatography. A. Jan, 2004 | Pubmed ID: 14753705 Contínua observação microscópica de alta resolução de replicativa envelhecimento em leveduras de brotamento Daphne H. E. W. Huberts1, Georges E. Janssens2, Sung Sik Lee3, Ima Avalos Vizcarra4, Matthias Heinemann1,5 1Molecular Systems Biology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 2Department for the Biology of Ageing, European Research Institute for the Biology of Ageing, University Medical Centre Groningen, University of Groningen, 3Institute of Biochemistry, ETH Zurich, 4Department of Health Sciences and Technology, ETH Zurich, 5Institute of Molecular Systems Biology, ETH Zurich JoVE 50143 Bioingegneria
Contínua observação microscópica de alta resolução de replicativa envelhecimento em leveduras de brotamento Daphne H. E. W. Huberts1, Georges E. Janssens2, Sung Sik Lee3, Ima Avalos Vizcarra4, Matthias Heinemann1,5 1Molecular Systems Biology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 2Department for the Biology of Ageing, European Research Institute for the Biology of Ageing, University Medical Centre Groningen, University of Groningen, 3Institute of Biochemistry, ETH Zurich, 4Department of Health Sciences and Technology, ETH Zurich, 5Institute of Molecular Systems Biology, ETH Zurich JoVE 50143 Bioingegneria