Melody A. Swartz Institute of Bioengineering and Swiss Institute of Experimental Cancer Research (ISREC) École Polytechnique Fédérale de Lausanne Biography Publications Institution JoVE Articles Melody A. Swartz has not added a biography. If you are Melody A. Swartz and would like to personalize this page please email our Author Liaison for assistance. Publications Introduction to the Special Issue on Lymphangiogenesis in Inflammation Angiogenesis. Apr, 2014 | Pubmed ID: 24671660 Emerging Roles of Lymphatic Endothelium in Regulating Adaptive Immunity The Journal of Clinical Investigation. Mar, 2014 | Pubmed ID: 24590280 Growth Factors Engineered for Super-affinity to the Extracellular Matrix Enhance Tissue Healing Science (New York, N.Y.). Feb, 2014 | Pubmed ID: 24558160 Targeting the Tumor-draining Lymph Node with Adjuvanted Nanoparticles Reshapes the Anti-tumor Immune Response Biomaterials. Jan, 2014 | Pubmed ID: 24144906 Optimization and Regeneration Kinetics of Lymphatic-specific Photodynamic Therapy in the Mouse Dermis Angiogenesis. Apr, 2014 | Pubmed ID: 23892627 Nanoparticle Conjugation of CpG Enhances Adjuvancy for Cellular Immunity and Memory Recall at Low Dose Proceedings of the National Academy of Sciences of the United States of America. Dec, 2013 | Pubmed ID: 24248387 Engineering Synthetic Vaccines Using Cues from Natural Immunity Nature Materials. Nov, 2013 | Pubmed ID: 24150416 VEGFR-3 Neutralization Inhibits Ovarian Lymphangiogenesis, Follicle Maturation, and Murine Pregnancy The American Journal of Pathology. Nov, 2013 | Pubmed ID: 24036251 Cooperative Roles of SDF-1α and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model PloS One. 2013 | Pubmed ID: 23869217 The Promotion of Endothelial Cell Attachment and Spreading Using FNIII10 Fused to VEGF-A165 Biomaterials. Aug, 2013 | Pubmed ID: 23683723 Peripherally Administered Nanoparticles Target Monocytic Myeloid Cells, Secondary Lymphoid Organs and Tumors in Mice PloS One. 2013 | Pubmed ID: 23626707 Normal Dendritic Cell Mobilization to Lymph Nodes Under Conditions of Severe Lymphatic Hypoplasia Journal of Immunology (Baltimore, Md. : 1950). May, 2013 | Pubmed ID: 23530147 Lymphatic Vasculature Mediates Macrophage Reverse Cholesterol Transport in Mice The Journal of Clinical Investigation. Apr, 2013 | Pubmed ID: 23524964 Tunable T Cell Immunity Towards a Protein Antigen Using Polymersomes Vs. Solid-core Nanoparticles Biomaterials. Jun, 2013 | Pubmed ID: 23478034 Intravital Immunofluorescence for Visualizing the Microcirculatory and Immune Microenvironments in the Mouse Ear Dermis PloS One. 2013 | Pubmed ID: 23451163 Interstitial Flow in a 3D Microenvironment Increases Glioma Invasion by a CXCR4-dependent Mechanism Cancer Research. Mar, 2013 | Pubmed ID: 23271726 ADAM17 Silencing in Mouse Colon Carcinoma Cells: the Effect on Tumoricidal Cytokines and Angiogenesis PloS One. 2012 | Pubmed ID: 23251384 Nanoparticle Size Influences the Magnitude and Quality of Mucosal Immune Responses After Intranasal Immunization Vaccine. Dec, 2012 | Pubmed ID: 23103199 Engineering Approaches to Immunotherapy Science Translational Medicine. Aug, 2012 | Pubmed ID: 22914624 Impaired Humoral Immunity and Tolerance in K14-VEGFR-3-Ig Mice That Lack Dermal Lymphatic Drainage Journal of Immunology (Baltimore, Md. : 1950). Sep, 2012 | Pubmed ID: 22844119 VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-presentation of Tumor Antigen by Lymph Node Lymphatics Cell Reports. Mar, 2012 | Pubmed ID: 22832193 Interstitial Fluid and Lymph Formation and Transport: Physiological Regulation and Roles in Inflammation and Cancer Physiological Reviews. Jul, 2012 | Pubmed ID: 22811424 Polymer Micelles with Pyridyl Disulfide-coupled Antigen Travel Through Lymphatics and Show Enhanced Cellular Responses Following Immunization Acta Biomaterialia. Sep, 2012 | Pubmed ID: 22698945 Dendritic Cell Activation and T Cell Priming with Adjuvant- and Antigen-loaded Oxidation-sensitive Polymersomes Biomaterials. Sep, 2012 | Pubmed ID: 22658634 肿瘤微环境复杂性: 新出现的在癌症治疗中的作用。 Cancer Research. May, 2012 | Pubmed ID: 22414581 Lymphatic and Interstitial Flow in the Tumour Microenvironment: Linking Mechanobiology with Immunity Nature Reviews. Cancer. Mar, 2012 | Pubmed ID: 22362216 Migration Dynamics of Breast Cancer Cells in a Tunable 3D Interstitial Flow Chamber Integrative Biology : Quantitative Biosciences from Nano to Macro. Apr, 2012 | Pubmed ID: 22143066 Multiscale Modeling of Lymphatic Drainage from Tissues Using Homogenization Theory Journal of Biomechanics. Jan, 2012 | Pubmed ID: 22036032 Nanoparticle Conjugation of Antigen Enhances Cytotoxic T-cell Responses in Pulmonary Vaccination Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 21969597 PEG-b-PPS-b-PEI Micelles and PEG-b-PPS/PEG-b-PPS-b-PEI Mixed Micelles As Non-viral Vectors for Plasmid DNA: Tumor Immunotoxicity in B16F10 Melanoma Biomaterials. Dec, 2011 | Pubmed ID: 21924769 Nano-sized Drug-loaded Micelles Deliver Payload to Lymph Node Immune Cells and Prolong Allograft Survival Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2011 | Pubmed ID: 21864593 Nanoparticle Conjugation and Pulmonary Delivery Enhance the Protective Efficacy of Ag85B and CpG Against Tuberculosis Vaccine. Sep, 2011 | Pubmed ID: 21787826 在 3D 下定义趋化因子渐变的树突状细胞趋化揭示了配体 CCL21 和 CCL19 的鉴别响应。 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21422278 Regulation of Tumor Invasion by Interstitial Fluid Flow Physical Biology. Feb, 2011 | Pubmed ID: 21301060 Tumor Cell Invasion is Promoted by Interstitial Flow-induced Matrix Priming by Stromal Fibroblasts Cancer Research. Feb, 2011 | Pubmed ID: 21245098 关于疫苗纳米聚丙烯硫化工程补体激活。 Biomaterials. Mar, 2011 | Pubmed ID: 21183216 PPS Nanoparticles As Versatile Delivery System to Induce Systemic and Broad Mucosal Immunity After Intranasal Administration Vaccine. Jan, 2011 | Pubmed ID: 21094269 Antigen Delivery to Dendritic Cells by Poly(propylene Sulfide) Nanoparticles with Disulfide Conjugated Peptides: Cross-presentation and T Cell Activation Vaccine. Nov, 2010 | Pubmed ID: 20934457 Role of Lymphatic Vessels in Tumor Immunity: Passive Conduits or Active Participants? Journal of Mammary Gland Biology and Neoplasia. Sep, 2010 | Pubmed ID: 20835756 Induction of Lymphoidlike Stroma and Immune Escape by Tumors That Express the Chemokine CCL21 Science (New York, N.Y.). May, 2010 | Pubmed ID: 20339029 Transmural Flow Modulates Cell and Fluid Transport Functions of Lymphatic Endothelium Circulation Research. Mar, 2010 | Pubmed ID: 20133901 Dermal Collagen and Lipid Deposition Correlate with Tissue Swelling and Hydraulic Conductivity in Murine Primary Lymphedema The American Journal of Pathology. Mar, 2010 | Pubmed ID: 20110415 Cells in 3D Matrices Under Interstitial Flow: Effects of Extracellular Matrix Alignment on Cell Shear Stress and Drag Forces Journal of Biomechanics. Mar, 2010 | Pubmed ID: 20006339 A Multichamber Fluidic Device for 3D Cultures Under Interstitial Flow with Live Imaging: Development, Characterization, and Applications Biotechnology and Bioengineering. Apr, 2010 | Pubmed ID: 19953672 Materials Engineering for Immunomodulation Nature. Nov, 2009 | Pubmed ID: 19940915 Fluid Flow Regulates Stromal Cell Organization and CCL21 Expression in a Tissue-engineered Lymph Node Microenvironment Journal of Immunology (Baltimore, Md. : 1950). Oct, 2009 | Pubmed ID: 19734211 Hypercholesterolemic Mice Exhibit Lymphatic Vessel Dysfunction and Degeneration The American Journal of Pathology. Sep, 2009 | Pubmed ID: 19679879 A Tissue-engineered Model of the Intestinal Lacteal for Evaluating Lipid Transport by Lymphatics Biotechnology and Bioengineering. Aug, 2009 | Pubmed ID: 19396808 3D 的趋化性研究的梯度缓冲区与琼脂糖微流控平台。 Biomedical Microdevices. Aug, 2009 | Pubmed ID: 19343497 In Vitro Models of Inhalation Toxicity and Disease. The Report of a FRAME Workshop Alternatives to Laboratory Animals : ATLA. Feb, 2009 | Pubmed ID: 19292579 3D Collagen Cultures Under Well-defined Dynamic Strain: a Novel Strain Device with a Porous Elastomeric Support Biotechnology and Bioengineering. May, 2009 | Pubmed ID: 19148875 Vascular Endothelial Growth Factor-C and C-C Chemokine Receptor 7 in Tumor Cell-lymphatic Cross-talk Promote Invasive Phenotype Cancer Research. Jan, 2009 | Pubmed ID: 19118020 Lymphatic Drainage Function and Its Immunological Implications: from Dendritic Cell Homing to Vaccine Design Seminars in Immunology. Apr, 2008 | Pubmed ID: 18201895 Effects of Dynamic Compression on Lentiviral Transduction in an in Vitro Airway Wall Model American Journal of Physiology. Lung Cellular and Molecular Physiology. Jan, 2008 | Pubmed ID: 18024723 Exploiting Lymphatic Transport and Complement Activation in Nanoparticle Vaccines Nature Biotechnology. Oct, 2007 | Pubmed ID: 17873867 Autologous Chemotaxis As a Mechanism of Tumor Cell Homing to Lymphatics Via Interstitial Flow and Autocrine CCR7 Signaling Cancer Cell. Jun, 2007 | Pubmed ID: 17560334 An Ultra-thin PDMS Membrane As a Bio/micro-nano Interface: Fabrication and Characterization Biomedical Microdevices. Aug, 2007 | Pubmed ID: 17516172 Interstitial Flow and Its Effects in Soft Tissues Annual Review of Biomedical Engineering. 2007 | Pubmed ID: 17459001 Bond-detach Lithography: a Method for Micro/nanolithography by Precision PDMS Patterning Small (Weinheim an Der Bergstrasse, Germany). Jan, 2007 | Pubmed ID: 17294484 Cooperative and Redundant Roles of VEGFR-2 and VEGFR-3 Signaling in Adult Lymphangiogenesis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2007 | Pubmed ID: 17210781 Regulation of Lymphatic Capillary Regeneration by Interstitial Flow in Skin American Journal of Physiology. Heart and Circulatory Physiology. May, 2007 | Pubmed ID: 17189348 A Driving Force for Change: Interstitial Flow As a Morphoregulator Trends in Cell Biology. Jan, 2007 | Pubmed ID: 17141502 Engineered Blood and Lymphatic Capillaries in 3-D VEGF-fibrin-collagen Matrices with Interstitial Flow Biotechnology and Bioengineering. Jan, 2007 | Pubmed ID: 17133613 Effects of Extracellular Fiber Architecture on Cell Membrane Shear Stress in a 3D Fibrous Matrix Journal of Biomechanics. 2007 | Pubmed ID: 16987520 Physiological 3D Tissue Model of the Airway Wall and Mucosa Nature Protocols. 2006 | Pubmed ID: 17406256 Targeting Dendritic Cells with Biomaterials: Developing the Next Generation of Vaccines Trends in Immunology. Dec, 2006 | Pubmed ID: 17049307 Secondary Lymphedema in the Mouse Tail: Lymphatic Hyperplasia, VEGF-C Upregulation, and the Protective Role of MMP-9 Microvascular Research. Nov, 2006 | Pubmed ID: 16876204 A Sensitive in Vivo Model for Quantifying Interstitial Convective Transport of Injected Macromolecules and Nanoparticles Journal of Applied Physiology (Bethesda, Md. : 1985). Oct, 2006 | Pubmed ID: 16763103 Characterization of Lymphangiogenesis in a Model of Adult Skin Regeneration American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2006 | Pubmed ID: 16648194 Autologous Morphogen Gradients by Subtle Interstitial Flow and Matrix Interactions Biophysical Journal. Jul, 2006 | Pubmed ID: 16603487 Extracellular Matrix Remodeling by Dynamic Strain in a Three-dimensional Tissue-engineered Human Airway Wall Model American Journal of Respiratory Cell and Molecular Biology. Sep, 2006 | Pubmed ID: 16601241 In Vivo Targeting of Dendritic Cells in Lymph Nodes with Poly(propylene Sulfide) Nanoparticles Journal of Controlled Release : Official Journal of the Controlled Release Society. May, 2006 | Pubmed ID: 16529839 Capturing Complex 3D Tissue Physiology in Vitro Nature Reviews. Molecular Cell Biology. Mar, 2006 | Pubmed ID: 16496023 Mechanisms of Interstitial Flow-induced Remodeling of Fibroblast-collagen Cultures Annals of Biomedical Engineering. Mar, 2006 | Pubmed ID: 16482410 Microarray Analysis of VEGF-C Responsive Genes in Human Lymphatic Endothelial Cells Lymphatic Research and Biology. 2005 | Pubmed ID: 16379588 Mechanobiology in the Third Dimension Annals of Biomedical Engineering. Nov, 2005 | Pubmed ID: 16341917 Synergy Between Interstitial Flow and VEGF Directs Capillary Morphogenesis in Vitro Through a Gradient Amplification Mechanism Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16249343 Interstitial Fluid Flow Induces Myofibroblast Differentiation and Collagen Alignment in Vitro Journal of Cell Science. Oct, 2005 | Pubmed ID: 16188933 Dendritic-cell Trafficking to Lymph Nodes Through Lymphatic Vessels Nature Reviews. Immunology. Aug, 2005 | Pubmed ID: 16056255 Overexpression of VEGF-C Causes Transient Lymphatic Hyperplasia but Not Increased Lymphangiogenesis in Regenerating Skin Circulation Research. Jun, 2005 | Pubmed ID: 15890974 Complete and Specific Inhibition of Adult Lymphatic Regeneration by a Novel VEGFR-3 Neutralizing Antibody Journal of the National Cancer Institute. Jan, 2005 | Pubmed ID: 15632376 Interstitial Flow Differentially Stimulates Blood and Lymphatic Endothelial Cell Morphogenesis in Vitro Microvascular Research. Nov, 2004 | Pubmed ID: 15501245 Signaling in Morphogenesis: Transport Cues in Morphogenesis Current Opinion in Biotechnology. Oct, 2003 | Pubmed ID: 14580587 An in Vitro Airway Wall Model of Remodeling American Journal of Physiology. Lung Cellular and Molecular Physiology. Aug, 2003 | Pubmed ID: 12851213 Interstitial Flow As a Guide for Lymphangiogenesis Circulation Research. Apr, 2003 | Pubmed ID: 12623882 Fibroblast Alignment Under Interstitial Fluid Flow Using a Novel 3-D Tissue Culture Model American Journal of Physiology. Heart and Circulatory Physiology. May, 2003 | Pubmed ID: 12531726 The Role of Interstitial Stress in Lymphatic Function and Lymphangiogenesis Annals of the New York Academy of Sciences. Dec, 2002 | Pubmed ID: 12543729 支气管上皮压缩规范地图激酶信号转导和 HB-表皮生长因子样生长因子的表达。 American Journal of Physiology. Lung Cellular and Molecular Physiology. May, 2002 | Pubmed ID: 11943653 与落射荧光组织基质成分和双光子显微镜的长期活体免疫荧光成像 Esra Güç*1, Manuel Fankhauser*1, Amanda W. Lund1,2, Melody A. Swartz1, Witold W. Kilarski1 1Institute of Bioengineering and Swiss Institute of Experimental Cancer Research (ISREC), École Polytechnique Fédérale de Lausanne, 2Department of Cell and Developmental Biology and Knight Cancer Institute, Oregon Health & Science University JoVE 51388 Bioingegneria
与落射荧光组织基质成分和双光子显微镜的长期活体免疫荧光成像 Esra Güç*1, Manuel Fankhauser*1, Amanda W. Lund1,2, Melody A. Swartz1, Witold W. Kilarski1 1Institute of Bioengineering and Swiss Institute of Experimental Cancer Research (ISREC), École Polytechnique Fédérale de Lausanne, 2Department of Cell and Developmental Biology and Knight Cancer Institute, Oregon Health & Science University JoVE 51388 Bioingegneria