Michael McManus Diabetes Center University of California, San Francisco - UCSF Biography Publications Institution JoVE Articles Michael McManus has not added a biography. If you are Michael McManus and would like to personalize this page please email our Author Liaison for assistance. Publications Widespread RNA 3'-end Oligouridylation in Mammals RNA (New York, N.Y.). Mar, 2012 | Pubmed ID: 22291204 An SiRNA Screen in Pancreatic Beta Cells Reveals a Role for Gpr27 in Insulin Production PLoS Genetics. Jan, 2012 | Pubmed ID: 22253604 Effect of Alveolar Epithelial Cell Plasticity on the Regulation of GM-CSF Expression American Journal of Physiology. Lung Cellular and Molecular Physiology. Jan, 2012 | Pubmed ID: 22227205 GM-CSF Provides Autocrine Protection for Murine Alveolar Epithelial Cells from Oxidant-induced Mitochondrial Injury American Journal of Physiology. Lung Cellular and Molecular Physiology. Feb, 2012 | Pubmed ID: 22140071 Polymerase II Promoter Strength Determines Efficacy of MicroRNA Adapted ShRNAs PloS One. 2011 | Pubmed ID: 22031824 Changes in 1-aminocyclopropane-1-carboxlate (ACC) Oxidase Expression and Enzyme Activity in Response to Excess Manganese in White Clover (Trifolium Repens L.) Plant Physiology and Biochemistry : PPB / Société Française De Physiologie Végétale. Sep, 2011 | Pubmed ID: 21530288 Genotypic Variation in the Sulfur Assimilation and Metabolism of Onion (Allium Cepa L.) I. Plant Composition and Transcript Accumulation Phytochemistry. Apr, 2011 | Pubmed ID: 21470645 Genotypic Variation in Sulphur Assimilation and Metabolism of Onion (Allium Cepa L.). II: Characterisation of ATP Sulphurylase Activity Phytochemistry. Apr, 2011 | Pubmed ID: 21459393 ACC Oxidase (ACO) Genes in Trifolium Occidentale (L.) and Their Relationship to ACO Genes in White Clover (T. Repens L.) and T. Pallescens (L.) Plant Physiology and Biochemistry : PPB / Société Française De Physiologie Végétale. Apr, 2011 | Pubmed ID: 21320784 The MicroRNA-processing Enzyme Dicer is Dispensable for Somite Segmentation but Essential for Limb Bud Positioning Developmental Biology. Mar, 2011 | Pubmed ID: 21256124 Posttranscriptional Silencing of Effector Cytokine MRNA Underlies the Anergic Phenotype of Self-reactive T Cells Immunity. Jan, 2011 | Pubmed ID: 21236706 Analysis of MicroRNA Knockouts in Mice Human Molecular Genetics. Oct, 2010 | Pubmed ID: 20805106 Host Specificity of Microsporidia Pathogenic to the Gypsy Moth, Lymantria Dispar (L.): Field Studies in Slovakia Journal of Invertebrate Pathology. Sep, 2010 | Pubmed ID: 20435042 Absidia Corymbifera Endocarditis: Survival After Treatment of Disseminated Mucormycosis with Radical Resection of Tricuspid Valve and Right Ventricular Free Wall The Journal of Thoracic and Cardiovascular Surgery. Apr, 2010 | Pubmed ID: 20304127 Dicer1 and MiR-219 Are Required for Normal Oligodendrocyte Differentiation and Myelination Neuron. Mar, 2010 | Pubmed ID: 20223197 Neuropathology of a Fatal Case of Posterior Reversible Encephalopathy Syndrome Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. Sep-Oct, 2010 | Pubmed ID: 20158377 Mechanisms of Suppression of Alveolar Epithelial Cell GM-CSF Expression in the Setting of Hyperoxic Stress American Journal of Physiology. Lung Cellular and Molecular Physiology. Mar, 2010 | Pubmed ID: 20034963 Dicer Ablation in Oligodendrocytes Provokes Neuronal Impairment in Mice Annals of Neurology. Dec, 2009 | Pubmed ID: 20035504 Expanded RNA-binding Activities of Mammalian Argonaute 2 Nucleic Acids Research. Dec, 2009 | Pubmed ID: 19808937 Dicer is Required for Proper Liver Zonation The Journal of Pathology. Nov, 2009 | Pubmed ID: 19718708 Chd1 Regulates Open Chromatin and Pluripotency of Embryonic Stem Cells Nature. Aug, 2009 | Pubmed ID: 19587682 Rapid Creation and Quantitative Monitoring of High Coverage ShRNA Libraries Nature Methods. Jun, 2009 | Pubmed ID: 19448642 LPS Induces KH-type Splicing Regulatory Protein-dependent Processing of MicroRNA-155 Precursors in Macrophages FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2009 | Pubmed ID: 19423639 Up-regulation of MiR-21 by HER2/neu Signaling Promotes Cell Invasion The Journal of Biological Chemistry. Jul, 2009 | Pubmed ID: 19419954 Residual MicroRNA Expression Dictates the Extent of Inner Ear Development in Conditional Dicer Knockout Mice Developmental Biology. Apr, 2009 | Pubmed ID: 19389351 Disruption of Dicer1 Induces Dysregulated Fetal Gene Expression and Promotes Hepatocarcinogenesis Gastroenterology. Jun, 2009 | Pubmed ID: 19272382 Characterization of the 1-aminocyclopropane-1-carboxylic Acid (ACC) Oxidase Multigene Family of Malus Domestica Borkh Phytochemistry. Feb, 2009 | Pubmed ID: 19223050 Genetic Analyses Reveal a Requirement for Dicer1 in the Mouse Urogenital Tract Mammalian Genome : Official Journal of the International Mammalian Genome Society. Mar, 2009 | Pubmed ID: 19169742 Sertoli Cell Dicer is Essential for Spermatogenesis in Mice Developmental Biology. Feb, 2009 | Pubmed ID: 19071104 Podocyte-specific Deletion of Dicer Alters Cytoskeletal Dynamics and Causes Glomerular Disease Journal of the American Society of Nephrology : JASN. Nov, 2008 | Pubmed ID: 18776121 Selective MiRNA Disruption in T Reg Cells Leads to Uncontrolled Autoimmunity The Journal of Experimental Medicine. Sep, 2008 | Pubmed ID: 18725525 Dicer1 is Required for Differentiation of the Mouse Male Germline Biology of Reproduction. Oct, 2008 | Pubmed ID: 18633141 Mouse Let-7 MiRNA Populations Exhibit RNA Editing That is Constrained in the 5'-seed/ Cleavage/anchor Regions and Stabilize Predicted Mmu-let-7a:mRNA Duplexes Genome Research. Oct, 2008 | Pubmed ID: 18614752 Quantifying Horizontal Transmission of Nosema Lymantriae, a Microsporidian Pathogen of the Gypsy Moth, Lymantria Dispar (Lep., Lymantriidae) in Field Cage Studies Journal of Invertebrate Pathology. Oct, 2008 | Pubmed ID: 18601930 Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2008 | Pubmed ID: 18434510 Dicer Loss in Striatal Neurons Produces Behavioral and Neuroanatomical Phenotypes in the Absence of Neurodegeneration Proceedings of the National Academy of Sciences of the United States of America. Apr, 2008 | Pubmed ID: 18385371 Michael T. McManus: Interrupting Biology [interview by Hema Bashyam] The Journal of Experimental Medicine. Mar, 2008 | Pubmed ID: 18347104 Unintentional MiRNA Ablation is a Risk Factor in Gene Knockout Studies: a Short Report PLoS Genetics. Feb, 2008 | Pubmed ID: 18282110 Sulfotransferase 4A1 The International Journal of Biochemistry & Cell Biology. 2008 | Pubmed ID: 18248844 Behind the Scenes of a Small RNA Gene-silencing Pathway Human Gene Therapy. Jan, 2008 | Pubmed ID: 18211225 Further Examination of Abscission Zone Cells As Ethylene Target Cells in Higher Plants Annals of Botany. Jan, 2008 | Pubmed ID: 17965027 Electrospun Nanofibre Fibrinogen for Urinary Tract Tissue Reconstruction Biomedical Materials (Bristol, England). Dec, 2007 | Pubmed ID: 18458483 Lentiviral Strategies for RNAi Knockdown of Neuronal Genes Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [et Al.]. Apr, 2007 | Pubmed ID: 18428658 Essential Role for Dicer During Skeletal Muscle Development Developmental Biology. Nov, 2007 | Pubmed ID: 17936265 Design and Implementation of a Portable Physiologic Data Acquisition System Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. Nov, 2007 | Pubmed ID: 17914307 MicroRNA Expression is Required for Pancreatic Islet Cell Genesis in the Mouse Diabetes. Dec, 2007 | Pubmed ID: 17804764 Complex Formation Between Recombinant ATP Sulfurylase and APS Reductase of Allium Cepa (L.) FEBS Letters. Sep, 2007 | Pubmed ID: 17692849 Extracellular Sulfatases, Elements of the Wnt Signaling Pathway, Positively Regulate Growth and Tumorigenicity of Human Pancreatic Cancer Cells PloS One. 2007 | Pubmed ID: 17460759 Dysregulation of Cardiogenesis, Cardiac Conduction, and Cell Cycle in Mice Lacking MiRNA-1-2 Cell. Apr, 2007 | Pubmed ID: 17397913 Electrospun Fibrinogen: Feasibility As a Tissue Engineering Scaffold in a Rat Cell Culture Model Journal of Biomedical Materials Research. Part A. May, 2007 | Pubmed ID: 17120217 Human Cytosolic Sulfotransferase SULT1A1 The International Journal of Biochemistry & Cell Biology. 2007 | Pubmed ID: 17110154 Duox2 Exhibits Potent Heme Peroxidase Activity in Human Respiratory Tract Epithelium FEBS Letters. Oct, 2006 | Pubmed ID: 16970942 Total Phenytoin Concentrations Do Not Accurately Predict Free Phenytoin Concentrations in Critically Ill Children Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. Sep, 2006 | Pubmed ID: 16885794 Vairimorpha Disparis N. Comb. (Microsporidia: Burenellidae): a Redescription and Taxonomic Revision of Thelohania Disparis Timofejeva 1956, a Microsporidian Parasite of the Gypsy Moth Lymantria Dispar (L.) (Lepidoptera: Lymantriidae) The Journal of Eukaryotic Microbiology. Jul-Aug, 2006 | Pubmed ID: 16872297 Mechanical Properties of Electrospun Fibrinogen Structures Acta Biomaterialia. Jan, 2006 | Pubmed ID: 16701855 Effect of Entomopathogenic Nematodes on Plectrodera Scalator (Fabricius) (Coleoptera: Cerambycidae) Journal of Invertebrate Pathology. May, 2006 | Pubmed ID: 16530219 Expression of 1-aminocyclopropane-1-carboxylate (ACC) Oxidase Genes During the Development of Vegetative Tissues in White Clover (Trifolium Repens L.) is Regulated by Ontological Cues Plant Molecular Biology. Feb, 2006 | Pubmed ID: 16514566 Dicer Function is Essential for Lung Epithelium Morphogenesis Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16452165 Nosema Chrysorrhoeae N. Sp. (Microsporidia), Isolated from Browntail Moth (Euproctis Chrysorrhoea L.) (Lepidoptera, Lymantriidae) in Bulgaria: Characterization and Phylogenetic Relationships Journal of Invertebrate Pathology. Feb, 2006 | Pubmed ID: 16410011 Human Sulfotransferases and Their Role in Chemical Metabolism Toxicological Sciences : an Official Journal of the Society of Toxicology. Mar, 2006 | Pubmed ID: 16322073 Hippocampal Atrophy in the Healthy is Initially Linear and Independent of Age Neurobiology of Aging. Oct, 2006 | Pubmed ID: 16168525 MicroRNAs and Endocrine Biology The Journal of Endocrinology. Dec, 2005 | Pubmed ID: 16423811 Human SULT1A Genes: Cloning and Activity Assays of the SULT1A Promoters Methods in Enzymology. 2005 | Pubmed ID: 16399348 The MicroRNA MiR-196 Acts Upstream of Hoxb8 and Shh in Limb Development Nature. Dec, 2005 | Pubmed ID: 16319892 The Structure of Human SULT1A1 Crystallized with Estradiol. An Insight into Active Site Plasticity and Substrate Inhibition with Multi-ring Substrates The Journal of Biological Chemistry. Dec, 2005 | Pubmed ID: 16221673 Removal of the N-linked Glycan Structure from the Peanut Peroxidase PrxPNC2: Influence on Protein Stability and Activity Phytochemistry. Aug, 2005 | Pubmed ID: 16112153 Slowing Down the Ras Lane: MiRNAs As Tumor Suppressors? Science's STKE : Signal Transduction Knowledge Environment. Aug, 2005 | Pubmed ID: 16107327 TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation Science (New York, N.Y.). Aug, 2005 | Pubmed ID: 16099986 The RNaseIII Enzyme Dicer is Required for Morphogenesis but Not Patterning of the Vertebrate Limb Proceedings of the National Academy of Sciences of the United States of America. Aug, 2005 | Pubmed ID: 16040801 Managing Unnecessary Variability in Patient Demand to Reduce Nursing Stress and Improve Patient Safety Joint Commission Journal on Quality and Patient Safety / Joint Commission Resources. Jun, 2005 | Pubmed ID: 15999963 Basilar Meningitis Associated with Ethmoid and Sphenoid Cephaloceles Pediatric Neurology. Jul, 2005 | Pubmed ID: 15993322 Molecular and Biochemical Characterisation of a Serine Acetyltransferase of Onion, Allium Cepa (L.) Phytochemistry. Jun, 2005 | Pubmed ID: 15949827 Hydrops Fetalis Caused by Homozygous Alpha-thalassemia and Rh Antigen Alloimmunization: Report of a Survivor and Literature Review Clinical Medicine & Research. Nov, 2004 | Pubmed ID: 15931362 Small RNAs and Immunity Immunity. Dec, 2004 | Pubmed ID: 15589164 The Human Sulfotransferase SULT1A1 Gene is Regulated in a Synergistic Manner by Sp1 and GA Binding Protein Molecular Pharmacology. Dec, 2004 | Pubmed ID: 15383623 MicroRNA-responsive 'sensor' Transgenes Uncover Hox-like and Other Developmentally Regulated Patterns of Vertebrate MicroRNA Expression Nature Genetics. Oct, 2004 | Pubmed ID: 15361871 Laparoscopic Varicocele Ligation: Are There Advantages Compared with the Microscopic Subinguinal Approach? Urology. Aug, 2004 | Pubmed ID: 15302494 Cre-lox-regulated Conditional RNA Interference from Transgenes Proceedings of the National Academy of Sciences of the United States of America. Jul, 2004 | Pubmed ID: 15240889 Perioperative Management of Diabetes Insipidus in Children Journal of Neurosurgical Anesthesiology. Jul, 2004 | Pubmed ID: 15211159 Queuing Theory Accurately Models the Need for Critical Care Resources Anesthesiology. May, 2004 | Pubmed ID: 15114227 Occurrence of Spruce Bark Beetles in Forest Stands at Different Levels of Air Pollution Stress Environmental Pollution (Barking, Essex : 1987). Jul, 2004 | Pubmed ID: 15046842 Active Site Mutations and Substrate Inhibition in Human Sulfotransferase 1A1 and 1A3 The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 14871892 Perioperative Management of Diabetes Insipidus in Children [corrected] Journal of Neurosurgical Anesthesiology. Jan, 2004 | Pubmed ID: 14676564 Localization of a Brain Sulfotransferase, SULT4A1, in the Human and Rat Brain: an Immunohistochemical Study The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Dec, 2003 | Pubmed ID: 14623933 MicroRNAs and Cancer Seminars in Cancer Biology. Aug, 2003 | Pubmed ID: 14563119 Identification and Characterisation of Proteinase Inhibitors and Their Genes from Seeds of Apple (Malus Domestica) Journal of Biochemistry. Jul, 2003 | Pubmed ID: 12944368 Variability in Surgical Caseload and Access to Intensive Care Services Anesthesiology. Jun, 2003 | Pubmed ID: 12766663 New International Long-term Ecological Research on Air Pollution Effects on the Carpathian Mountain Forests, Central Europe Environment International. Jun, 2003 | Pubmed ID: 12676229 RNA Interference of Influenza Virus Production by Directly Targeting MRNA for Degradation and Indirectly Inhibiting All Viral RNA Transcription Proceedings of the National Academy of Sciences of the United States of America. Mar, 2003 | Pubmed ID: 12594334 A Lentivirus-based System to Functionally Silence Genes in Primary Mammalian Cells, Stem Cells and Transgenic Mice by RNA Interference Nature Genetics. Mar, 2003 | Pubmed ID: 12590264 Structure of a Human Carcinogen-converting Enzyme, SULT1A1. Structural and Kinetic Implications of Substrate Inhibition The Journal of Biological Chemistry. Feb, 2003 | Pubmed ID: 12471039 Small Interfering RNA-mediated Gene Silencing in T Lymphocytes Journal of Immunology (Baltimore, Md. : 1950). Nov, 2002 | Pubmed ID: 12421955 Proteomics. Sep, 2002 | Pubmed ID: 12362330 CP110, a Cell Cycle-dependent CDK Substrate, Regulates Centrosome Duplication in Human Cells Developmental Cell. Sep, 2002 | Pubmed ID: 12361598 Gene Silencing in Mammals by Small Interfering RNAs Nature Reviews. Genetics. Oct, 2002 | Pubmed ID: 12360232 Association of the SULT1A1 R213H Polymorphism with Colorectal Cancer Clinical and Experimental Pharmacology & Physiology. Sep, 2002 | Pubmed ID: 12165038 Gene Silencing Using Micro-RNA Designed Hairpins RNA (New York, N.Y.). Jun, 2002 | Pubmed ID: 12088155 Combined Endoscopic Resection and Brachytherapy for Recurrent Intrapelvic Wilms Tumor The Journal of Urology. Jun, 2002 | Pubmed ID: 11992083 Lentivirus उत्पादन Xiaoyin Wang1, Michael McManus1 1Diabetes Center, University of California, San Francisco - UCSF JoVE 1499 Biologia
Lentivirus उत्पादन Xiaoyin Wang1, Michael McManus1 1Diabetes Center, University of California, San Francisco - UCSF JoVE 1499 Biologia