Michael Weller Department of Neurology, Laboratory of Molecular Neuro Oncology University Hospital of Zurich Biography Publications Institution JoVE Articles Michael Weller has not added a biography. If you are Michael Weller and would like to personalize this page please email our Author Liaison for assistance. Publications Program Director and Chief Resident Perspectives on the Educational Environment of US Radiation Oncology Programs Practical Radiation Oncology. Jun, 2016 | Pubmed ID: 27523441 The Role of Molecular Diagnostics in the Management of Patients with Gliomas Current Treatment Options in Oncology. Oct, 2016 | Pubmed ID: 27501915 Long-term Analysis of the NOA-04 Randomized Phase III Trial of Sequential Radiochemotherapy of Anaplastic Glioma with PCV or Temozolomide Neuro-oncology. Jul, 2016 | Pubmed ID: 27370396 Interleukin-33 in Human Gliomas: Expression and Prognostic Significance Oncology Letters. Jul, 2016 | Pubmed ID: 27347163 Boswellic Acid Activity Against Glioblastoma Stem-like Cells Oncology Letters. Jun, 2016 | Pubmed ID: 27313764 Reply to F. Felix Et Al and M.F. Fay Et Al Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2016 | Pubmed ID: 27298403 Osteopontin in Cerebrospinal Fluid As Diagnostic Biomarker for Central Nervous System Lymphoma Journal of Neuro-oncology. Aug, 2016 | Pubmed ID: 27294357 Limited Role for Transforming Growth Factor-β Pathway Activation-mediated Escape from VEGF Inhibition in Murine Glioma Models Neuro-oncology. Jun, 2016 | Pubmed ID: 27286797 Direct Contact with Perivascular Tumor Cells Enhances Integrin αvβ3 Signaling and Migration of Endothelial Cells Oncotarget. May, 2016 | Pubmed ID: 27270311 Immunotherapy of Brain Cancer Oncology Research and Treatment. 2016 | Pubmed ID: 27260656 Current State of Immune-Based Therapies for Glioblastoma American Society of Clinical Oncology Educational Book / ASCO. American Society of Clinical Oncology. Meeting. 2016 | Pubmed ID: 27249715 Gene-Tailored Treatments for Brain Disorders: Challenges and Opportunities Public Health Genomics. 2016 | Pubmed ID: 27238144 Phase II Study of Radiotherapy and Temsirolimus Versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma Without MGMT Promoter Hypermethylation (EORTC 26082) Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2016 | Pubmed ID: 27143690 Chemotherapy for Intracranial Ependymoma in Adults BMC Cancer. 2016 | Pubmed ID: 27108407 Response Assessment in Neuro-Oncology Working Group and European Association for Neuro-Oncology Recommendations for the Clinical Use of PET Imaging in Gliomas Neuro-oncology. Apr, 2016 | Pubmed ID: 27106405 Somatostatin-receptor-targeted Radionuclide Therapy for Progressive Meningioma: Benefit Linked to 68Ga-DOTATATE/-TOC Uptake Neuro-oncology. Apr, 2016 | Pubmed ID: 27106404 Glioblastoma in the Canton of Zurich, Switzerland Revisited: 2005 to 2009 Cancer. Jul, 2016 | Pubmed ID: 27088883 Pharmacotherapies for the Treatment of Glioblastoma - Current Evidence and Perspectives Expert Opinion on Pharmacotherapy. Jun, 2016 | Pubmed ID: 27052640 Corticosteroids Compromise Survival in Glioblastoma Brain : a Journal of Neurology. May, 2016 | Pubmed ID: 27020328 Quality Issues of Research Antibodies Analytical Chemistry Insights. 2016 | Pubmed ID: 27013861 Autocrine VEGFR1 and VEGFR2 Signaling Promotes Survival in Human Glioblastoma Models in Vitro and in Vivo Neuro-oncology. Mar, 2016 | Pubmed ID: 27009237 Therapy for Secondary CNS Involvement in Malignant Lymphomas: No Standard Yet! Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. May, 2016 | Pubmed ID: 27001566 [Gliomas – What I Have to Know in Ten Questions] Praxis. Mar, 2016 | Pubmed ID: 26980684 Altered Intraoperative Cerebrovascular Reactivity in Brain Areas of High-grade Glioma Recurrence Magnetic Resonance Imaging. Jul, 2016 | Pubmed ID: 26968146 Glioblastoma Handbook of Clinical Neurology. 2016 | Pubmed ID: 26948367 Cilengitide in Newly Diagnosed Glioblastoma: Biomarker Expression and Outcome Oncotarget. Mar, 2016 | Pubmed ID: 26918452 MicroRNA-138 Promotes Acquired Alkylator Resistance in Glioblastoma by Targeting the Bcl-2-interacting Mediator BIM Oncotarget. Mar, 2016 | Pubmed ID: 26887050 68Gallium-DOTATATE PET in Meningioma: A Reliable Predictor of Tumor Growth Rate? Neuro-oncology. Jul, 2016 | Pubmed ID: 26865086 Therapeutic Options in Recurrent Glioblastoma--An Update Critical Reviews in Oncology/hematology. Mar, 2016 | Pubmed ID: 26830009 Complete Resection of Contrast-enhancing Tumor Volume is Associated with Improved Survival in Recurrent Glioblastoma-results from the DIRECTOR Trial Neuro-oncology. Apr, 2016 | Pubmed ID: 26823503 Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2016 | Pubmed ID: 26786929 Prolonged-release Fampridine in Multiple Sclerosis: Improved Ambulation Effected by Changes in Walking Pattern Multiple Sclerosis (Houndmills, Basingstoke, England). Jan, 2016 | Pubmed ID: 26762672 Erratum To: Gliomatosis Cerebri: No Evidence for a Separate Brain Tumor Entity Acta Neuropathologica. Feb, 2016 | Pubmed ID: 26744347 Control of Glioma Cell Migration and Invasiveness by GDF-15 Oncotarget. Feb, 2016 | Pubmed ID: 26741507 Predicting Outcome of Epilepsy After Meningioma Resection Neuro-oncology. Jul, 2016 | Pubmed ID: 26683139 Amino Acid Positron Emission Tomography to Monitor Chemotherapy Response and Predict Seizure Control and Progression-free Survival in WHO Grade II Gliomas Neuro-oncology. May, 2016 | Pubmed ID: 26578622 Gliomatosis Cerebri: No Evidence for a Separate Brain Tumor Entity Acta Neuropathologica. Feb, 2016 | Pubmed ID: 26493382 Development of Highly Sensitive and Selective Antibodies for the Detection of the Explosive Pentaerythritol Tetranitrate (PETN) by Bioisosteric Replacement Journal of Molecular Recognition : JMR. Feb, 2016 | Pubmed ID: 26463875 Kinetics of Tumor Size and Peritumoral Brain Edema Before, During, and After Systemic Therapy in Recurrent WHO Grade II or III Meningioma Neuro-oncology. Mar, 2016 | Pubmed ID: 26354929 Glioma Nature Reviews. Disease Primers. 2015 | Pubmed ID: 27188790 New Insights into Acquired Temozolomide Resistance in Glioblastoma? Brain : a Journal of Neurology. Dec, 2015 | Pubmed ID: 26598490 Immunotherapy Response Assessment in Neuro-oncology: a Report of the RANO Working Group The Lancet. Oncology. Nov, 2015 | Pubmed ID: 26545842 Immunosuppressive Mechanisms in Glioblastoma Neuro-oncology. Nov, 2015 | Pubmed ID: 26516226 Dedication: Andrew T. Parsa Neuro-oncology. Nov, 2015 | Pubmed ID: 26516222 Introduction Neuro-oncology. Nov, 2015 | Pubmed ID: 26516220 Neurology--the Next 10 Years Nature Reviews. Neurology. Nov, 2015 | Pubmed ID: 26503922 Clinical Neuropathology Mini-review 6-2015: PD-L1: Emerging Biomarker in Glioblastoma? Clinical Neuropathology. Nov-Dec, 2015 | Pubmed ID: 26501438 Computer-assisted Quantification of Motile and Invasive Capabilities of Cancer Cells Scientific Reports. 2015 | Pubmed ID: 26486848 Interferon-β Modulates the Innate Immune Response Against Glioblastoma Initiating Cells PloS One. 2015 | Pubmed ID: 26441059 Immunotherapy for Glioblastoma: Concepts and Challenges Current Opinion in Neurology. Dec, 2015 | Pubmed ID: 26402401 Management of Diffusely Infiltrating Glioma in the Elderly Current Opinion in Oncology. Nov, 2015 | Pubmed ID: 26397765 Consensus Recommendations for a Standardized Brain Tumor Imaging Protocol in Clinical Trials Neuro-oncology. Sep, 2015 | Pubmed ID: 26250565 Diagnosis and Treatment of Primary CNS Lymphoma in Immunocompetent Patients: Guidelines from the European Association for Neuro-Oncology The Lancet. Oncology. Jul, 2015 | Pubmed ID: 26149884 Management of Neoplastic Meningitis Chinese Clinical Oncology. Jun, 2015 | Pubmed ID: 26112812 Brain Metastasis Research: a Late Awakening Chinese Clinical Oncology. Jun, 2015 | Pubmed ID: 26112803 Modulation of Cerebral Endothelial Cell Function by TGF-β in Glioblastoma: VEGF-dependent Angiogenesis Versus Endothelial Mesenchymal Transition Oncotarget. Sep, 2015 | Pubmed ID: 26090865 Adult IDH Wild Type Astrocytomas Biologically and Clinically Resolve into Other Tumor Entities Acta Neuropathologica. Sep, 2015 | Pubmed ID: 26087904 Corticosteroid Use in Neuro-oncology: an Update Neuro-oncology Practice. Mar, 2015 | Pubmed ID: 26034636 Malignant Optic Glioma - the Spectrum of Disease in a Case Series Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Jul, 2015 | Pubmed ID: 26004076 [Neuro-oncology] Der Nervenarzt. Jun, 2015 | Pubmed ID: 25986916 Transforming Growth Factor-β Pathway Activity in Glioblastoma Oncotarget. Mar, 2015 | Pubmed ID: 25849941 Prognostic Impact of B-cell Lymphoma 6 in Primary CNS Lymphoma Neuro-oncology. Jul, 2015 | Pubmed ID: 25817328 Efficacy of Surgery and Further Treatment of Progressive Glioblastoma World Neurosurgery. Aug, 2015 | Pubmed ID: 25797075 Molecular Classification of Diffuse Cerebral WHO Grade II/III Gliomas Using Genome- and Transcriptome-wide Profiling Improves Stratification of Prognostically Distinct Patient Groups Acta Neuropathologica. May, 2015 | Pubmed ID: 25783747 Randomized Phase III Study of Whole-brain Radiotherapy for Primary CNS Lymphoma Neurology. Mar, 2015 | Pubmed ID: 25716362 Phase 1 Dose-escalation Study of the Antiplacental Growth Factor Monoclonal Antibody RO5323441 Combined with Bevacizumab in Patients with Recurrent Glioblastoma Neuro-oncology. Jul, 2015 | Pubmed ID: 25665807 Adjuvant Versus Neoadjuvant Androgen Deprivation with Radiotherapy for Prostate Cancer: Does Sequencing Matter? Clinical Genitourinary Cancer. Jun, 2015 | Pubmed ID: 25660127 MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2015 | Pubmed ID: 25655102 Chromosome 7 Gain and DNA Hypermethylation at the HOXA10 Locus Are Associated with Expression of a Stem Cell Related HOX-signature in Glioblastoma Genome Biology. 2015 | Pubmed ID: 25622821 Biological Tumor Volume in 18FET-PET Before Radiochemotherapy Correlates with Survival in GBM Neurology. Feb, 2015 | Pubmed ID: 25609769 Differentially Regulated MiRNAs As Prognostic Biomarkers in the Blood of Primary CNS Lymphoma Patients European Journal of Cancer (Oxford, England : 1990). Feb, 2015 | Pubmed ID: 25534293 ATRX and IDH1-R132H Immunohistochemistry with Subsequent Copy Number Analysis and IDH Sequencing As a Basis for an "integrated" Diagnostic Approach for Adult Astrocytoma, Oligodendroglioma and Glioblastoma Acta Neuropathologica. Jan, 2015 | Pubmed ID: 25427834 Clinically Isolated Neurosarcoidosis: a Recommended Diagnostic Path European Neurology. 2015 | Pubmed ID: 25401278 Programmed Death Ligand 1 Expression and Tumor-infiltrating Lymphocytes in Glioblastoma Neuro-oncology. Aug, 2015 | Pubmed ID: 25355681 Dynamic 18F-FET PET in Suspected WHO Grade II Gliomas Defines Distinct Biological Subgroups with Different Clinical Courses International Journal of Cancer. May, 2015 | Pubmed ID: 25311315 Prognostic Impact of Intraocular Involvement in Primary CNS Lymphoma: Experience from the G-PCNSL-SG1 Trial Annals of Hematology. Mar, 2015 | Pubmed ID: 25217230 Differential Regulation of TGF-β-induced, ALK-5-mediated VEGF Release by SMAD2/3 Versus SMAD1/5/8 Signaling in Glioblastoma Neuro-oncology. Feb, 2015 | Pubmed ID: 25165192 Carboplatin and Etoposide in Heavily Pretreated Patients with Progressive High-Grade Glioma Chemotherapy. 2014 | Pubmed ID: 26496463 The Management of Lomustine Overdose in Malignant Glioma Patients Neuro-oncology Practice. Dec, 2014 | Pubmed ID: 26034630 Does Cilengitide Deserve Another Chance?-Authors' Reply The Lancet. Oncology. Dec, 2014 | Pubmed ID: 25456377 Antiangiogenic Therapy for Glioblastoma: Current Status and Future Prospects Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2014 | Pubmed ID: 25398844 Challenges to Targeting Epidermal Growth Factor Receptor in Glioblastoma: Escape Mechanisms and Combinatorial Treatment Strategies Neuro-oncology. Oct, 2014 | Pubmed ID: 25342600 How Stemlike Are Sphere Cultures from Long-term Cancer Cell Lines? Lessons from Mouse Glioma Models Journal of Neuropathology and Experimental Neurology. Nov, 2014 | Pubmed ID: 25289892 MicroRNA-mediated Down-regulation of NKG2D Ligands Contributes to Glioma Immune Escape Oncotarget. Sep, 2014 | Pubmed ID: 25277195 Reciprocal Modulation of Aβ42 Aggregation by Copper and Homocysteine Frontiers in Aging Neuroscience. 2014 | Pubmed ID: 25249976 Cilengitide Combined with Standard Treatment for Patients with Newly Diagnosed Glioblastoma with Methylated MGMT Promoter (CENTRIC EORTC 26071-22072 Study): a Multicentre, Randomised, Open-label, Phase 3 Trial The Lancet. Oncology. Sep, 2014 | Pubmed ID: 25163906 Letter to the Editor: "The Role of Imaging in the Management of Progressive Glioblastoma. A Systematic Review and Evidence-based Clinical Practice Guideline" [J Neurooncol 2014; 118:435-460] Journal of Neuro-oncology. Dec, 2014 | Pubmed ID: 25151508 αvβ3, αvβ5 and αvβ6 Integrins in Brain Metastases of Lung Cancer Clinical & Experimental Metastasis. Oct, 2014 | Pubmed ID: 25150423 Primary Central Nervous System Lymphoma in the Elderly Oncology Research and Treatment. 2014 | Pubmed ID: 25138296 EANO Guideline for the Diagnosis and Treatment of Anaplastic Gliomas and Glioblastoma The Lancet. Oncology. Aug, 2014 | Pubmed ID: 25079102 Assessing CpG Island Methylator Phenotype, 1p/19q Codeletion, and MGMT Promoter Methylation from Epigenome-wide Data in the Biomarker Cohort of the NOA-04 Trial Neuro-oncology. Dec, 2014 | Pubmed ID: 25028501 Integrated DNA Methylation and Copy-number Profiling Identify Three Clinically and Biologically Relevant Groups of Anaplastic Glioma Acta Neuropathologica. Oct, 2014 | Pubmed ID: 25008768 Primary Glioblastoma Cultures: Can Profiling of Stem Cell Markers Predict Radiotherapy Sensitivity? Journal of Neurochemistry. Oct, 2014 | Pubmed ID: 24976529 The Vanishing Role of Whole Brain Radiotherapy for Primary Central Nervous System Lymphoma Neuro-oncology. Aug, 2014 | Pubmed ID: 24958097 3-Nitropropionic Acid-induced Ischemia Tolerance in the Rat Brain is Mediated by Reduced Metabolic Activity and Cerebral Blood Flow Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Sep, 2014 | Pubmed ID: 24938399 MGMT Testing--the Challenges for Biomarker-based Glioma Treatment Nature Reviews. Neurology. Jul, 2014 | Pubmed ID: 24912512 Addition of Lomustine for Bevacizumab-refractory Recurrent Glioblastoma Acta Oncologica (Stockholm, Sweden). Oct, 2014 | Pubmed ID: 24862539 Questions Regarding the Optimal Use of Bevacizumab in Glioblastoma: a Moving Target Neuro-oncology. Jun, 2014 | Pubmed ID: 24826844 Hypoxia Enhances the Antiglioma Cytotoxicity of B10, a Glycosylated Derivative of Betulinic Acid PloS One. 2014 | Pubmed ID: 24743710 Clinical Management and Outcome of Histologically Verified Adult Brainstem Gliomas in Switzerland: a Retrospective Analysis of 21 Patients Journal of Neuro-oncology. Jun, 2014 | Pubmed ID: 24736829 Neuropathological Characteristics of Progression After Prolonged Response to Bevacizumab in Multifocal Hemangioblastoma Oncology Research and Treatment. 2014 | Pubmed ID: 24732646 ERGO: a Pilot Study of Ketogenic Diet in Recurrent Glioblastoma International Journal of Oncology. Jun, 2014 | Pubmed ID: 24728273 Genomic Profiling Reveals Distinctive Molecular Relapse Patterns in IDH1/2 Wild-type Glioblastoma Genes, Chromosomes & Cancer. Jul, 2014 | Pubmed ID: 24706357 Molecular Characterization of Long-term Survivors of Glioblastoma Using Genome- and Transcriptome-wide Profiling International Journal of Cancer. Oct, 2014 | Pubmed ID: 24615357 Assessment and Prognostic Significance of the Epidermal Growth Factor Receptor VIII Mutation in Glioblastoma Patients Treated with Concurrent and Adjuvant Temozolomide Radiochemotherapy International Journal of Cancer. May, 2014 | Pubmed ID: 24614983 Etoposide/carboplatin Chemotherapy for the Treatment of Metastatic Myxomatous Cerebral Aneurysms Journal of Neurology. Apr, 2014 | Pubmed ID: 24603973 Clinical Reasoning: a 30-year-old Woman with Recurrent Seizures and a Cerebral Lesion Progressing over 2 Decades Neurology. Feb, 2014 | Pubmed ID: 24536067 Interferon-β Induces Loss of Spherogenicity and Overcomes Therapy Resistance of Glioblastoma Stem Cells Molecular Cancer Therapeutics. Apr, 2014 | Pubmed ID: 24526161 Amyotrophic Lateral Sclerosis After Embolization of Cerebral Arterioveneous Malformations Journal of Neurology. Apr, 2014 | Pubmed ID: 24509642 Cilengitide Treatment of Newly Diagnosed Glioblastoma Patients Does Not Alter Patterns of Progression Journal of Neuro-oncology. Jan, 2014 | Pubmed ID: 24442484 Neuro-oncology in 2013: Improving Outcome in Newly Diagnosed Malignant Glioma Nature Reviews. Neurology. Feb, 2014 | Pubmed ID: 24419684 Genetic Variants of Homocysteine Metabolism and Multiple Sclerosis: a Case-control Study Neuroscience Letters. Mar, 2014 | Pubmed ID: 24412677 MTOR Target NDRG1 Confers MGMT-dependent Resistance to Alkylating Chemotherapy Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24367102 Thymosin β 4 Gene Silencing Decreases Stemness and Invasiveness in Glioblastoma Brain : a Journal of Neurology. Feb, 2014 | Pubmed ID: 24355709 Treatment of Primary CNS Lymphoma Current Treatment Options in Neurology. Jan, 2014 | Pubmed ID: 24343307 A Disintegrin and Metalloproteinases 10 and 17 Modulate the Immunogenicity of Glioblastoma-initiating Cells Neuro-oncology. Mar, 2014 | Pubmed ID: 24327582 Levetiracetam and Pregabalin for Antiepileptic Monotherapy in Patients with Primary Brain Tumors. A Phase II Randomized Study Neuro-oncology. Apr, 2014 | Pubmed ID: 24311644 The Legend of Cytomegalovirus and Glioblastoma Lives On Neuro-oncology. Jan, 2014 | Pubmed ID: 24311642 Single-institution Retrospective Series of Gamma Knife Radiosurgery in the Treatment of Multiple Sclerosis-related Trigeminal Neuralgia: Factors That Predict Efficacy Stereotactic and Functional Neurosurgery. 2014 | Pubmed ID: 24217153 Immunological Challenges for Peptide-based Immunotherapy in Glioblastoma Cancer Treatment Reviews. Mar, 2014 | Pubmed ID: 24064197 Intratumoral IL-12 Combined with CTLA-4 Blockade Elicits T Cell-mediated Glioma Rejection The Journal of Experimental Medicine. Dec, 2013 | Pubmed ID: 24277150 Immunoassays and Biosensors for the Detection of Cyanobacterial Toxins in Water Sensors (Basel, Switzerland). 2013 | Pubmed ID: 24196435 Distribution of TERT Promoter Mutations in Pediatric and Adult Tumors of the Nervous System Acta Neuropathologica. Dec, 2013 | Pubmed ID: 24154961 Malignant Astrocytoma in Elderly Patients: Where Do We Stand? Current Opinion in Neurology. Dec, 2013 | Pubmed ID: 24152817 Tumor-associated Edema in Brain Cancer Patients: Pathogenesis and Management Expert Review of Anticancer Therapy. Nov, 2013 | Pubmed ID: 24152171 EGFR Phosphorylates Tumor-derived EGFRvIII Driving STAT3/5 and Progression in Glioblastoma Cancer Cell. Oct, 2013 | Pubmed ID: 24135280 Invasion Patterns in Brain Metastases of Solid Cancers Neuro-oncology. Dec, 2013 | Pubmed ID: 24084410 Prognostic or Predictive Value of MGMT Promoter Methylation in Gliomas Depends on IDH1 Mutation Neurology. Oct, 2013 | Pubmed ID: 24068788 Differential Expression of the Tumor Suppressor A-kinase Anchor Protein 12 in Human Diffuse and Pilocytic Astrocytomas is Regulated by Promoter Methylation Journal of Neuropathology and Experimental Neurology. Oct, 2013 | Pubmed ID: 24042196 APO010, a Synthetic Hexameric CD95 Ligand, Induces Death of Human Glioblastoma Stem-like Cells Anticancer Research. Sep, 2013 | Pubmed ID: 24023281 Long-term Survival in Primary Glioblastoma with Versus Without Isocitrate Dehydrogenase Mutations Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2013 | Pubmed ID: 23918605 Anaplastic Oligodendroglioma: a New Treatment Paradigm and Current Controversies Current Treatment Options in Oncology. Dec, 2013 | Pubmed ID: 23907441 ATRX Loss Refines the Classification of Anaplastic Gliomas and Identifies a Subgroup of IDH Mutant Astrocytic Tumors with Better Prognosis Acta Neuropathologica. Sep, 2013 | Pubmed ID: 23904111 Molecular Neuro-oncology in Clinical Practice: a New Horizon The Lancet. Oncology. Aug, 2013 | Pubmed ID: 23896276 JC Virus Granule Cell Neuronopathy and GCN-IRIS Under Natalizumab Treatment Annals of Neurology. Oct, 2013 | Pubmed ID: 23868420 Angiogenesis Inhibition for Glioblastoma at the Edge: Beyond AVAGlio and RTOG 0825 Neuro-oncology. Aug, 2013 | Pubmed ID: 23864129 End-of-life Caregivers' Perception of Medical and Psychological Support During the Final Weeks of Glioma Patients: a Questionnaire-based Survey Neuro-oncology. Sep, 2013 | Pubmed ID: 23814266 The Cascade Radical Cyclisation Approach to Prenylated Alkaloids: Synthesis of Stephacidin A and Notoamide B Organic & Biomolecular Chemistry. Aug, 2013 | Pubmed ID: 23797367 Are We Ready for a Randomized Trial of Valproic Acid in Newly Diagnosed Glioblastoma? Neuro-oncology. Jul, 2013 | Pubmed ID: 23788268 Acid Sphingomyelinase-ceramide System Mediates Effects of Antidepressant Drugs Nature Medicine. Jul, 2013 | Pubmed ID: 23770692 The Time of Maximum Post-ischemic Hyperperfusion Indicates Infarct Growth Following Transient Experimental Ischemia PloS One. 2013 | Pubmed ID: 23741488 Refined Brain Tumor Diagnostics and Stratified Therapies: the Requirement for a Multidisciplinary Approach Acta Neuropathologica. Jul, 2013 | Pubmed ID: 23689616 Glioma Cell Death Induced by Irradiation or Alkylating Agent Chemotherapy is Independent of the Intrinsic Ceramide Pathway PloS One. 2013 | Pubmed ID: 23667632 αv-Integrin Isoform Expression in Primary Human Tumors and Brain Metastases International Journal of Cancer. Nov, 2013 | Pubmed ID: 23661241 Malignant Astrocytomas of Elderly Patients Lack Favorable Molecular Markers: an Analysis of the NOA-08 Study Collective Neuro-oncology. Aug, 2013 | Pubmed ID: 23595628 High-dose Praziquantel Therapy for Cerebral Sparganosis Journal of Neurology. May, 2013 | Pubmed ID: 23546305 Selective, Sensitive, and Rapid Analysis with Lateral-flow Assays Based on Antibody-gated Dye-delivery Systems: the Example of Triacetone Triperoxide Chemistry (Weinheim an Der Bergstrasse, Germany). Mar, 2013 | Pubmed ID: 23447084 Assessing the MGMT Status in Glioblastoma: One Step Forward, Two Steps Back? Neuro-oncology. Mar, 2013 | Pubmed ID: 23430603 Integrin Control of the Transforming Growth Factor-β Pathway in Glioblastoma Brain : a Journal of Neurology. Feb, 2013 | Pubmed ID: 23378223 The Costs of Disorders of the Brain in Switzerland: an Update from the European Brain Council Study for 2010 Swiss Medical Weekly. 2013 | Pubmed ID: 23297120 Expression of Integrins αvβ3 and αvβ5 and Their Ligands in Primary and Secondary Central Nervous System Neoplasms Histology and Histopathology. Jun, 2013 | Pubmed ID: 23238957 Bevacizumab Alone or in Combination with Irinotecan in Recurrent WHO Grade II and Grade III Gliomas European Neurology. 2013 | Pubmed ID: 23182901 Standards of Care for Treatment of Recurrent Glioblastoma--are We There Yet? Neuro-oncology. Jan, 2013 | Pubmed ID: 23136223 Optimal Management of Elderly Patients with Glioblastoma Cancer Treatment Reviews. Jun, 2013 | Pubmed ID: 22722053 Shaping the Glioma Immune Microenvironment Through Tryptophan Metabolism CNS Oncology. Sep, 2012 | Pubmed ID: 25054303 Primary Central Nervous System Tumors: Pathogenesis and Therapy Archives of Neurology. Jul, 2012 | Pubmed ID: 23754022 Personalized Care in Neuro-oncology Coming of Age: Why We Need MGMT and 1p/19q Testing for Malignant Glioma Patients in Clinical Practice Neuro-oncology. Sep, 2012 | Pubmed ID: 23095825 Angiogenesis Inhibition: Quo Vadis? Neuro-oncology. Nov, 2012 | Pubmed ID: 23095501 Prime Time for Molecular Marker Diagnostics in Neuro-oncology Current Opinion in Neurology. Dec, 2012 | Pubmed ID: 23041956 A Unifying Review of Bioassay-guided Fractionation, Effect-directed Analysis and Related Techniques Sensors (Basel, Switzerland). 2012 | Pubmed ID: 23012539 Deletion of the Ageing Gene P66Shc Reduces Early Stroke Size Following Ischaemia/reperfusion Brain Injury European Heart Journal. Sep, 2012 | Pubmed ID: 23008506 Epidermal Growth Factor Receptor: a Re-emerging Target in Glioblastoma Current Opinion in Neurology. Dec, 2012 | Pubmed ID: 23007009 Surgery for Primary CNS Lymphoma? Challenging a Paradigm Neuro-oncology. Dec, 2012 | Pubmed ID: 22984018 Epilepsy Meets Cancer: When, Why, and What to Do About It? The Lancet. Oncology. Sep, 2012 | Pubmed ID: 22935237 Outcome of Elderly Patients with Primary CNS Lymphoma in the G-PCNSL-SG-1 Trial Neurology. Aug, 2012 | Pubmed ID: 22895585 CT-only Planning for Gamma Knife Radiosurgery in the Treatment of Trigeminal Neuralgia: Methodology and Outcomes from a Single Institution Journal of Medical Imaging and Radiation Oncology. Aug, 2012 | Pubmed ID: 22883661 Microglia: a Novel Treatment Target in Gliomas Neuro-oncology. Aug, 2012 | Pubmed ID: 22851682 Antiangiogenic Treatment for Multiple CNS Hemangioblastomas Onkologie. 2012 | Pubmed ID: 22846977 MGMT Methylation Analysis of Glioblastoma on the Infinium Methylation BeadChip Identifies Two Distinct CpG Regions Associated with Gene Silencing and Outcome, Yielding a Prediction Model for Comparisons Across Datasets, Tumor Grades, and CIMP-status Acta Neuropathologica. Oct, 2012 | Pubmed ID: 22810491 Comparison of the Fragmentation Behavior of Differentially Metal-coded Affinity Tag (MeCAT)-labeled Peptides Journal of Mass Spectrometry : JMS. Jul, 2012 | Pubmed ID: 22791256 Drug-related Problems and Factors Influencing Acceptance of Clinical Pharmacologists` Alerts in a Large Cohort of Neurology Inpatients Swiss Medical Weekly. 2012 | Pubmed ID: 22777799 Progressive Dopamine and Hypocretin Deficiencies in Parkinson's Disease: is There an Impact on Sleep and Wakefulness? Journal of Sleep Research. Dec, 2012 | Pubmed ID: 22747735 HLA-E Contributes to an Immune-inhibitory Phenotype of Glioblastoma Stem-like Cells Journal of Neuroimmunology. Sep, 2012 | Pubmed ID: 22688424 Immunoassays As High-throughput Tools: Monitoring Spatial and Temporal Variations of Carbamazepine, Caffeine and Cetirizine in Surface and Wastewaters Chemosphere. Nov, 2012 | Pubmed ID: 22682895 Pathogenesis and Management of Primary CNS Lymphoma Expert Review of Anticancer Therapy. May, 2012 | Pubmed ID: 22594897 Temozolomide Chemotherapy Alone Versus Radiotherapy Alone for Malignant Astrocytoma in the Elderly: the NOA-08 Randomised, Phase 3 Trial The Lancet. Oncology. Jul, 2012 | Pubmed ID: 22578793 Distinct Molecular Mechanisms of Acquired Resistance to Temozolomide in Glioblastoma Cells Journal of Neurochemistry. Jul, 2012 | Pubmed ID: 22564186 Phase 2 Trial Design in Neuro-oncology Revisited: a Report from the RANO Group The Lancet Oncology. May, 2012 | Pubmed ID: 22554547 More on the Immune Privilege of Glioblastoma Neuro-oncology. May, 2012 | Pubmed ID: 22539528 Comparative Evaluation of the Drug Interaction Screening Programs MediQ and ID PHARMA CHECK in Neurological Inpatients Pharmacoepidemiology and Drug Safety. Aug, 2012 | Pubmed ID: 22517594 Antiepileptic Drugs and Vitamin B6 Plasma Levels in Adult Patients Epilepsy Research. Aug, 2012 | Pubmed ID: 22464176 Prognostic Value of Three Different Methods of MGMT Promoter Methylation Analysis in a Prospective Trial on Newly Diagnosed Glioblastoma PloS One. 2012 | Pubmed ID: 22428052 Clinical Implications of Molecular Neuropathology and Biomarkers for Malignant Glioma Current Neurology and Neuroscience Reports. Jun, 2012 | Pubmed ID: 22427102 Is There a World Beyond Bevacizumab in Targeting Angiogenesis in Glioblastoma? Expert Opinion on Investigational Drugs. May, 2012 | Pubmed ID: 22413865 Autoimmune Myasthenia Gravis After Sternal Fracture Case Reports in Neurology. Jan, 2012 | Pubmed ID: 22393321 Sustained Efficacy of Natalizumab in the Treatment of Relapsing-remitting Multiple Sclerosis Independent of Disease Activity and Disability at Baseline: Real-life Data from a Swiss Cohort Clinical Neuropharmacology. Mar-Apr, 2012 | Pubmed ID: 22318192 Monitoring the Glioma Tropism of Bone Marrow-derived Progenitor Cells by 2-photon Laser Scanning Microscopy and Positron Emission Tomography Neuro-oncology. Apr, 2012 | Pubmed ID: 22298526 Extremely Sensitive and Selective Antibodies Against the Explosive 2,4,6-trinitrotoluene by Rational Design of a Structurally Optimized Hapten Journal of Molecular Recognition : JMR. Feb, 2012 | Pubmed ID: 22290770 Individualized Targeted Therapy for Glioblastoma: Fact or Fiction? Cancer Journal (Sudbury, Mass.). Jan-Feb, 2012 | Pubmed ID: 22290256 Presence of an Oligodendroglioma-like Component in Newly Diagnosed Glioblastoma Identifies a Pathogenetically Heterogeneous Subgroup and Lacks Prognostic Value: Central Pathology Review of the EORTC_26981/NCIC_CE.3 Trial Acta Neuropathologica. Jun, 2012 | Pubmed ID: 22249618 Immunology of Brain Tumors Handbook of Clinical Neurology. 2012 | Pubmed ID: 22230434 Non-invasive Monitoring of Immunization Progress in Mice Via IgG from Feces In Vivo (Athens, Greece). Jan-Feb, 2012 | Pubmed ID: 22210717 Predictive Impact of MGMT Promoter Methylation in Glioblastoma of the Elderly International Journal of Cancer. Sep, 2012 | Pubmed ID: 22139906 Costimulatory Protein 4IgB7H3 Drives the Malignant Phenotype of Glioblastoma by Mediating Immune Escape and Invasiveness Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2012 | Pubmed ID: 22080438 2-Hydroxyglutarate Concentration in Serum from Patients with Gliomas Does Not Correlate with IDH1/2 Mutation Status or Tumor Size International Journal of Cancer. Aug, 2012 | Pubmed ID: 21913188 Intravenous and Oral Levetiracetam in Patients with a Suspected Primary Brain Tumor and Symptomatic Seizures Undergoing Neurosurgery: the HELLO Trial Acta Neurochirurgica. Feb, 2012 | Pubmed ID: 21909835 Clinical Trials in Neuro-oncology: One Step Forward, Two Steps Back? Current Opinion in Neurology. Dec, 2011 | Pubmed ID: 21986679 An Endogenous Tumour-promoting Ligand of the Human Aryl Hydrocarbon Receptor Nature. Oct, 2011 | Pubmed ID: 21976023 Geriatric Neuro-oncology: from Mythology to Biology Current Opinion in Neurology. Dec, 2011 | Pubmed ID: 21968549 CAMTA1 is a Novel Tumour Suppressor Regulated by MiR-9/9* in Glioblastoma Stem Cells The EMBO Journal. Oct, 2011 | Pubmed ID: 21857646 An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery Martin H. M. Sailer1, Durga Sarvepalli2, Catherine Brégère3, Urs Fisch3, Marin Guentchev4, Michael Weller6, Raphael Guzman3, Bernhard Bettler1, Arkasubhra Ghosh*2, Gregor Hutter*5 1Dept. of Biomedicine, Pharmacenter, University of Basel, 2Molecular Signalling and Gene Therapy, Narayana Nethralaya Foundation, Narayana Health City, 3Brain Ischemia and Regeneration, Department of Biomedicine, University Hospital Basel, 4Department of Neurosurgery, Klinikum Idar-Oberstein, 5Department of Neurosurgery and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, 6Department of Neurology, Laboratory of Molecular Neuro Oncology, University Hospital of Zurich JoVE 54018 Biologia dello sviluppo
An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery Martin H. M. Sailer1, Durga Sarvepalli2, Catherine Brégère3, Urs Fisch3, Marin Guentchev4, Michael Weller6, Raphael Guzman3, Bernhard Bettler1, Arkasubhra Ghosh*2, Gregor Hutter*5 1Dept. of Biomedicine, Pharmacenter, University of Basel, 2Molecular Signalling and Gene Therapy, Narayana Nethralaya Foundation, Narayana Health City, 3Brain Ischemia and Regeneration, Department of Biomedicine, University Hospital Basel, 4Department of Neurosurgery, Klinikum Idar-Oberstein, 5Department of Neurosurgery and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, 6Department of Neurology, Laboratory of Molecular Neuro Oncology, University Hospital of Zurich JoVE 54018 Biologia dello sviluppo