Michal Toborek Department of Biochemistry and Molecular Biology, Miller School of Medicine University of Miami Biography Publications Institution JoVE Articles Michal Toborek has not added a biography. If you are Michal Toborek and would like to personalize this page please email our Author Liaison for assistance. Publications Role of Aging in Blood-Brain Barrier Dysfunction and Susceptibility to SARS-CoV-2 Infection: Impacts on Neurological Symptoms of COVID-19 Fluids and Barriers of the CNS. Aug, 2022 | Pubmed ID: 35982454 Circadian Disruption Alters Gut Barrier Integrity Via a ß-catenin-MMP-related Pathway Molecular and Cellular Biochemistry. Aug, 2022 | Pubmed ID: 35976519 Pitfalls of Antiretroviral Therapy: Current Status and Long-Term CNS Toxicity Biomolecules. 06, 2022 | Pubmed ID: 35883450 SARS-CoV-2 Infection of Human Brain Microvascular Endothelial Cells Leads to Inflammatory Activation Through NF-κB Non-canonical Pathway and Mitochondrial Remodeling Research Square. Jun, 2022 | Pubmed ID: 35734086 SARS-CoV-2 Infection of Human Brain Microvascular Endothelial Cells Leads to Inflammatory Activation Through NF-κB Non-canonical Pathway and Mitochondrial Remodeling BioRxiv : the Preprint Server for Biology. Jun, 2022 | Pubmed ID: 35734080 Opioid Antagonist Nanodrugs Successfully Attenuate the Severity of Ischemic Stroke Molecular Pharmaceutics. 07, 2022 | Pubmed ID: 35506882 Successful Correction of Hyperglycemia is Critical for Weight Loss and a Decrease in Cardiovascular Risk in Obese Patients The Journal of Nutritional Biochemistry. 08, 2022 | Pubmed ID: 35472434 Brain Barriers Virtual: an Interim Solution or Future Opportunity? Fluids and Barriers of the CNS. Mar, 2022 | Pubmed ID: 35232464 Loss of Skeletal Muscle Mass and Intracellular Water As Undesired Outcomes of Weight Reduction in Obese Hyperglycemic Women: A Short-Term Longitudinal Study International Journal of Environmental Research and Public Health. 01, 2022 | Pubmed ID: 35055821 In Vivo Targeting of the Neurovascular Unit: Challenges and Advancements Cellular and Molecular Neurobiology. Oct, 2022 | Pubmed ID: 34086179 Bicarbonate Supplementation Via Lactate Efflux Improves Anaerobic and Cognitive Performance in Elite Combat Sport Athletes Biology of Sport. Oct, 2021 | Pubmed ID: 34937963 Correction To: Methamphetamine Enhances HIV-Induced Aberrant Proliferation of Neural Progenitor Cells Via the FOXO3-Mediated Mechanism Molecular Neurobiology. Nov, 2021 | Pubmed ID: 34617256 Synergistic Impairment of the Neurovascular Unit by HIV-1 Infection and Methamphetamine Use: Implications for HIV-1-Associated Neurocognitive Disorders Viruses. 09, 2021 | Pubmed ID: 34578464 Brain-Accumulating Nanoparticles for Assisting Astrocytes to Reduce Human Immunodeficiency Virus and Drug Abuse-Induced Neuroinflammation and Oxidative Stress ACS Nano. 10, 2021 | Pubmed ID: 34355558 Expression of SARS-CoV-2-related Receptors in Cells of the Neurovascular Unit: Implications for HIV-1 Infection Journal of Neuroinflammation. Jul, 2021 | Pubmed ID: 34325716 Methamphetamine Enhances HIV-Induced Aberrant Proliferation of Neural Progenitor Cells Via the FOXO3-Mediated Mechanism Molecular Neurobiology. Nov, 2021 | Pubmed ID: 33983546 Extracellular Vesicles Regulate Gap Junction-mediated Intercellular Communication and HIV-1 Infection of Human Neural Progenitor Cells Neurobiology of Disease. 07, 2021 | Pubmed ID: 33962010 Expression of SARS-CoV-2-related Receptors in Cells of the Neurovascular Unit: Implications for HIV-1 Infection Research Square. Feb, 2021 | Pubmed ID: 33655239 Cerebral Vascular Toxicity of Antiretroviral Therapy Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. 03, 2021 | Pubmed ID: 31209776 Occludin, Caveolin-1, and Alix Form a Multi-protein Complex and Regulate HIV-1 Infection of Brain Pericytes FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 12, 2020 | Pubmed ID: 33058236 Substances of Abuse and the Blood Brain Barrier: Interactions with Physical Exercise Neuroscience and Biobehavioral Reviews. 12, 2020 | Pubmed ID: 33038347 The Paradox of HIV Blood-Brain Barrier Penetrance and Antiretroviral Drug Delivery Deficiencies Trends in Neurosciences. 09, 2020 | Pubmed ID: 32682564 Urinary Incontinence in Women: Biofeedback As an Innovative Treatment Method Therapeutic Advances in Urology. Jan-Dec, 2020 | Pubmed ID: 32647538 Reduced-Beclin1-Expressing Mice Infected with Zika-R103451 and Viral-Associated Pathology During Pregnancy Viruses. 06, 2020 | Pubmed ID: 32498399 HIV-1 and Amyloid Beta Remodel Proteome of Brain Endothelial Extracellular Vesicles International Journal of Molecular Sciences. Apr, 2020 | Pubmed ID: 32326569 Physical Activity Reduces Anxiety and Regulates Brain Fatty Acid Synthesis Molecular Brain. 04, 2020 | Pubmed ID: 32303271 The Effect of Neurofeedback Training on the Visual Processing Efficiency in Judo Athletes Journal of Human Kinetics. Jan, 2020 | Pubmed ID: 32148586 Extracellular Vesicle-mediated Amyloid Transfer to Neural Progenitor Cells: Implications for RAGE and HIV Infection Molecular Brain. 02, 2020 | Pubmed ID: 32066471 Viral Vector-Mediated Gene Transfer of Glutamic Acid Decarboxylase for Chronic Pain Treatment: A Literature Review Human Gene Therapy. 04, 2020 | Pubmed ID: 32041431 Toxicity of ZnO/TiO -conjugated Carbon-based Nanohybrids on the Coastal Marine Alga Thalassiosira Pseudonana Environmental Toxicology. Jan, 2020 | Pubmed ID: 31515868 Selective Disruption of the Blood-Brain Barrier by Zika Virus Frontiers in Microbiology. 2019 | Pubmed ID: 31620112 Opioid Antagonists As Potential Therapeutics for Ischemic Stroke Progress in Neurobiology. 11, 2019 | Pubmed ID: 31398359 Antibacterial Effects of Graphene- and Carbon-nanotube-based Nanohybrids on Escherichia Coli: Implications for Treating Multidrug-resistant Bacteria Journal of Environmental Management. Oct, 2019 | Pubmed ID: 31247368 Targeting the HIV-infected Brain to Improve Ischemic Stroke Outcome Nature Communications. 05, 2019 | Pubmed ID: 31043599 Treatment of Antibiotic-resistant Bacteria by Encapsulation of ZnO Nanoparticles in an Alginate Biopolymer: Insights into Treatment Mechanisms Journal of Hazardous Materials. 07, 2019 | Pubmed ID: 30909137 Methamphetamine-associated Cognitive Decline is Attenuated by Neutralizing IL-1 Signaling Brain, Behavior, and Immunity. 08, 2019 | Pubmed ID: 30885840 Blood-brain Barrier Pericytes As a Target for HIV-1 Infection Brain : a Journal of Neurology. 03, 2019 | Pubmed ID: 30668645 Targeted Mitochondrial COQ Delivery Attenuates Antiretroviral-Drug-Induced Senescence of Neural Progenitor Cells Molecular Pharmaceutics. 02, 2019 | Pubmed ID: 30592424 Chronic Ingestion of Sodium and Potassium Bicarbonate, with Potassium, Magnesium and Calcium Citrate Improves Anaerobic Performance in Elite Soccer Players Nutrients. Nov, 2018 | Pubmed ID: 30388775 Effects of Coating Materials on Antibacterial Properties of Industrial and Sunscreen-derived Titanium-dioxide Nanoparticles on Escherichia Coli Chemosphere. Oct, 2018 | Pubmed ID: 29870909 Circadian Disruption Changes Gut Microbiome Taxa and Functional Gene Composition Frontiers in Microbiology. 2018 | Pubmed ID: 29706947 Cigarette Smoke Initiates Oxidative Stress-Induced Cellular Phenotypic Modulation Leading to Cerebral Aneurysm Pathogenesis Arteriosclerosis, Thrombosis, and Vascular Biology. 03, 2018 | Pubmed ID: 29348119 Intestinal Exposure to PCB 153 Induces Inflammation Via the ATM/NEMO Pathway Toxicology and Applied Pharmacology. 01, 2018 | Pubmed ID: 29197519 Methamphetamine Increases HIV Infectivity in Neural Progenitor Cells The Journal of Biological Chemistry. 01, 2018 | Pubmed ID: 29158267 Occludin Regulates Glucose Uptake and ATP Production in Pericytes by Influencing AMP-activated Protein Kinase Activity Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 02, 2018 | Pubmed ID: 28718701 HIV Alters Gap Junction-Mediated Intercellular Communication in Human Brain Pericytes Frontiers in Molecular Neuroscience. 2017 | Pubmed ID: 29311803 Development of Magneto-plasmonic Nanoparticles for Multimodal Image-guided Therapy to the Brain Nanoscale. Jan, 2017 | Pubmed ID: 27976764 Extracellular Vesicles of the Blood-brain Barrier: Role in the HIV-1 Associated Amyloid Beta Pathology Molecular and Cellular Neurosciences. Dec, 2016 | Pubmed ID: 28040512 Antiretroviral Treatment with Efavirenz Disrupts the Blood-Brain Barrier Integrity and Increases Stroke Severity Scientific Reports. Dec, 2016 | Pubmed ID: 28008980 Exercise Protects Against Methamphetamine-induced Aberrant Neurogenesis Scientific Reports. Sep, 2016 | Pubmed ID: 27677455 Solving the Blood-Brain Barrier Challenge for the Effective Treatment of HIV Replication in the Central Nervous System Current Pharmaceutical Design. 2016 | Pubmed ID: 27464720 Extracellular Vesicles of the Blood-brain Barrier Tissue Barriers. Jan-Mar, 2016 | Pubmed ID: 27141419 Blood-brain Barrier Remodeling During Brain Metastasis Formation Molecular Medicine (Cambridge, Mass.). Jan, 2016 | Pubmed ID: 26837070 Biological Activity of Selenium: Revisited IUBMB Life. Feb, 2016 | Pubmed ID: 26714931 Dietary Selenium Supplementation Modulates Growth of Brain Metastatic Tumors and Changes the Expression of Adhesion Molecules in Brain Microvessels Biological Trace Element Research. Aug, 2016 | Pubmed ID: 26706037 Occludin Controls HIV Transcription in Brain Pericytes Via Regulation of SIRT-1 Activation FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2016 | Pubmed ID: 26601824 Environmental PCBs in Guánica Bay, Puerto Rico: Implications for Community Health Environmental Science and Pollution Research International. Feb, 2016 | Pubmed ID: 26122576 Lipid Rafts Regulate PCB153-induced Disruption of Occludin and Brain Endothelial Barrier Function Through Protein Phosphatase 2A and Matrix Metalloproteinase-2 Toxicology and Applied Pharmacology. Sep, 2015 | Pubmed ID: 26080028 Exercise Maintains Blood-brain Barrier Integrity During Early Stages of Brain Metastasis Formation Biochemical and Biophysical Research Communications. Aug, 2015 | Pubmed ID: 26056010 Dysregulation of Endoplasmic Reticulum Stress and Autophagic Responses by the Antiretroviral Drug Efavirenz Molecular Pharmacology. Aug, 2015 | Pubmed ID: 25987489 Selenoglycoproteins Attenuate Adhesion of Tumor Cells to the Brain Microvascular Endothelium Via a Process Involving NF-κB Activation The Journal of Nutritional Biochemistry. Feb, 2015 | Pubmed ID: 25465156 Transcriptional Profile of HIV-induced Nuclear Translocation of Amyloid β in Brain Endothelial Cells Archives of Medical Research. Nov, 2014 | Pubmed ID: 25446617 Extraction of Diffuse Correlation Spectroscopy Flow Index by Integration of Nth-order Linear Model with Monte Carlo Simulation Applied Physics Letters. May, 2014 | Pubmed ID: 24926099 Exercise Modulates Redox-sensitive Small GTPase Activity in the Brain Microvasculature in a Model of Brain Metastasis Formation PloS One. 2014 | Pubmed ID: 24804765 Disruption of Epithelial Barrier by Quorum-sensing N-3-(oxododecanoyl)-homoserine Lactone is Mediated by Matrix Metalloproteinases American Journal of Physiology. Gastrointestinal and Liver Physiology. Jun, 2014 | Pubmed ID: 24742991 Interactions of PCBs with Human Serum Albumin: in Vitro Spectroscopic Study Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy. Apr, 2014 | Pubmed ID: 24513710 HIV-1 Stimulates Nuclear Entry of Amyloid Beta Via Dynamin Dependent EEA1 and TGF-β/Smad Signaling Experimental Cell Research. Apr, 2014 | Pubmed ID: 24491918 PPAR Agonist-mediated Protection Against HIV Tat-induced Cerebrovascular Toxicity is Enhanced in MMP-9-deficient Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Apr, 2014 | Pubmed ID: 24424383 Methamphetamine-induced Occludin Endocytosis is Mediated by the Arp2/3 Complex-regulated Actin Rearrangement The Journal of Biological Chemistry. Nov, 2013 | Pubmed ID: 24081143 Endovascular Embolization of Varicoceles Using N-butyl Cyanoacrylate (NBCA) Glue Polish Journal of Radiology. Apr, 2013 | Pubmed ID: 23807881 Voluntary Exercise Protects Against Methamphetamine-induced Oxidative Stress in Brain Microvasculature and Disruption of the Blood-brain Barrier Molecular Neurodegeneration. Jun, 2013 | Pubmed ID: 23799892 Targeting the Therapeutic Effects of Exercise on Redox-sensitive Mechanisms in the Vascular Endothelium During Tumor Progression IUBMB Life. Jul, 2013 | Pubmed ID: 23757193 TLR4 Signaling is Involved in Brain Vascular Toxicity of PCB153 Bound to Nanoparticles PloS One. 2013 | Pubmed ID: 23690990 Supplementation with Selenium-enriched Yeast Attenuates Brain Metastatic Growth Nutrition and Cancer. 2013 | Pubmed ID: 23659448 Exercise Attenuates PCB-induced Changes in the Mouse Gut Microbiome Environmental Health Perspectives. Jun, 2013 | Pubmed ID: 23632211 Amyloid Beta Accumulation in HIV-1-infected Brain: The Role of the Blood Brain Barrier IUBMB Life. Jan, 2013 | Pubmed ID: 23225609 Autophagy is Involved in Nanoalumina-induced Cerebrovascular Toxicity Nanomedicine : Nanotechnology, Biology, and Medicine. Feb, 2013 | Pubmed ID: 22687898 Cerebrovascular Toxicity of PCB153 is Enhanced by Binding to Silica Nanoparticles Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Dec, 2012 | Pubmed ID: 23081707 Infection of Human Pericytes by HIV-1 Disrupts the Integrity of the Blood-brain Barrier Journal of Cellular and Molecular Medicine. Dec, 2012 | Pubmed ID: 22947176 Lipopolysaccharide Potentiates Polychlorinated Biphenyl-induced Disruption of the Blood-brain Barrier Via TLR4/IRF-3 Signaling Toxicology. Dec, 2012 | Pubmed ID: 22906770 EGCG Protects Endothelial Cells Against PCB 126-induced Inflammation Through Inhibition of AhR and Induction of Nrf2-regulated Genes Toxicology and Applied Pharmacology. Jun, 2012 | Pubmed ID: 22521609 Lipid Rafts and Functional Caveolae Regulate HIV-induced Amyloid Beta Accumulation in Brain Endothelial Cells Biochemical and Biophysical Research Communications. May, 2012 | Pubmed ID: 22490665 Proinflammatory Adhesion Molecules Facilitate Polychlorinated Biphenyl-mediated Enhancement of Brain Metastasis Formation Toxicological Sciences : an Official Journal of the Society of Toxicology. Apr, 2012 | Pubmed ID: 22240979 HIV-1 Tat Triggers Nuclear Localization of ZO-1 Via Rho Signaling and CAMP Response Element-binding Protein Activation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2012 | Pubmed ID: 22219277 HIV-1 Tat-induced Cerebrovascular Toxicity is Enhanced in Mice with Amyloid Deposits Neurobiology of Aging. Aug, 2012 | Pubmed ID: 21764480 EMMPRIN Regulates Cytoskeleton Reorganization and Cell Adhesion in Prostate Cancer The Prostate. Jan, 2012 | Pubmed ID: 21563192 Epigallocatechin-gallate Stimulates NF-E2-related Factor and Heme Oxygenase-1 Via Caveolin-1 Displacement The Journal of Nutritional Biochemistry. Feb, 2012 | Pubmed ID: 21447442 Methamphetamine Alters Occludin Expression Via NADPH Oxidase-induced Oxidative Insult and Intact Caveolae Journal of Cellular and Molecular Medicine. Feb, 2012 | Pubmed ID: 21435178 Diffuse Optical Monitoring of Repeated Cerebral Ischemia in Mice Optics Express. Oct, 2011 | Pubmed ID: 21997041 PPARα and PPARγ Protect Against HIV-1-induced MMP-9 Overexpression Via Caveolae-associated ERK and Akt Signaling FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2011 | Pubmed ID: 21840940 HIV-1-induced Alterations of Claudin-5 Expression at the Blood-brain Barrier Level Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21717370 Caveolae: a Regulatory Platform for Nutritional Modulation of Inflammatory Diseases The Journal of Nutritional Biochemistry. Sep, 2011 | Pubmed ID: 21292468 Omega-3 Fatty Acid Oxidation Products Prevent Vascular Endothelial Cell Activation by Coplanar Polychlorinated Biphenyls Toxicology and Applied Pharmacology. Feb, 2011 | Pubmed ID: 21130106 Epigallocatechin Gallate-mediated Protection Against Tumor Necrosis Factor-α-induced Monocyte Chemoattractant Protein-1 Expression is Heme Oxygenase-1 Dependent Metabolism: Clinical and Experimental. Oct, 2010 | Pubmed ID: 20580034 Deficiency of Telomerase Activity Aggravates the Blood-brain Barrier Disruption and Neuroinflammatory Responses in a Model of Experimental Stroke Journal of Neuroscience Research. Oct, 2010 | Pubmed ID: 20564349 Polychlorinated Biphenyl-induced VCAM-1 Expression is Attenuated in Aortic Endothelial Cells Isolated from Caveolin-1 Deficient Mice Toxicology and Applied Pharmacology. Jul, 2010 | Pubmed ID: 20406653 The Role of Caveolae in Endothelial Cell Dysfunction with a Focus on Nutrition and Environmental Toxicants Journal of Cellular and Molecular Medicine. Oct, 2010 | Pubmed ID: 20406324 Polychlorinated Biphenyls Disrupt Intestinal Integrity Via NADPH Oxidase-induced Alterations of Tight Junction Protein Expression Environmental Health Perspectives. Jul, 2010 | Pubmed ID: 20299304 Inhibition of Telomerase Activity Alters Tight Junction Protein Expression and Induces Transendothelial Migration of HIV-1-infected Cells American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2010 | Pubmed ID: 20139322 Polychlorinated Biphenyls Disrupt Blood-brain Barrier Integrity and Promote Brain Metastasis Formation Environmental Health Perspectives. Apr, 2010 | Pubmed ID: 20064788 HIV-1-induced Amyloid Beta Accumulation in Brain Endothelial Cells is Attenuated by Simvastatin Molecular and Cellular Neurosciences. Feb, 2010 | Pubmed ID: 19944163 Intact Lipid Rafts Regulate HIV-1 Tat Protein-induced Activation of the Rho Signaling and Upregulation of P-glycoprotein in Brain Endothelial Cells Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2010 | Pubmed ID: 19794400 Quercetin Blocks Caveolae-dependent Pro-inflammatory Responses Induced by Co-planar PCBs Environment International. Nov, 2010 | Pubmed ID: 19608276 NADPH Oxidase and Lipid Raft-associated Redox Signaling Are Required for PCB153-induced Upregulation of Cell Adhesion Molecules in Human Brain Endothelial Cells Toxicology and Applied Pharmacology. Oct, 2009 | Pubmed ID: 19632255 Induction of Gene Pattern Changes Associated with Dysfunctional Lipid Metabolism Induced by Dietary Fat and Exposure to a Persistent Organic Pollutant Toxicology Letters. Sep, 2009 | Pubmed ID: 19467301 Up-regulation of Endothelial Monocyte Chemoattractant Protein-1 by Coplanar PCB77 is Caveolin-1-dependent Toxicology and Applied Pharmacology. May, 2009 | Pubmed ID: 19265715 Flavonoids Protect Against Intercellular Adhesion Molecule-1 Induction by Benzo[a]pyrene Bulletin of Environmental Contamination and Toxicology. Jul, 2009 | Pubmed ID: 19214356 PPARalpha and PPARgamma Attenuate HIV-induced Dysregulation of Tight Junction Proteins by Modulations of Matrix Metalloproteinase and Proteasome Activities FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2009 | Pubmed ID: 19141539 Vessel Microport Technique for Applications in Cerebrovascular Research Journal of Neuroscience Research. May, 2009 | Pubmed ID: 19115415 Nicotine Attenuates INOS Expression and Contributes to Neuroprotection in a Compressive Model of Spinal Cord Injury Journal of Neuroscience Research. Mar, 2009 | Pubmed ID: 18855939 Role of Caveolin-1 in EGCG-mediated Protection Against Linoleic-acid-induced Endothelial Cell Activation The Journal of Nutritional Biochemistry. Mar, 2009 | Pubmed ID: 18656337 Impact of Nutrition on PCB Toxicity Environmental Toxicology and Pharmacology. Mar, 2008 | Pubmed ID: 21783859 Zinc Nutritional Status Modulates Expression of Ahr-responsive P450 Enzymes in Vascular Endothelial Cells Environmental Toxicology and Pharmacology. Mar, 2008 | Pubmed ID: 19255596 Zinc Deficiency Induces Vascular Pro-inflammatory Parameters Associated with NF-kappaB and PPAR Signaling Journal of the American College of Nutrition. Oct, 2008 | Pubmed ID: 18845708 Manufactured Aluminum Oxide Nanoparticles Decrease Expression of Tight Junction Proteins in Brain Vasculature Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Dec, 2008 | Pubmed ID: 18830698 The Role of Fatty Acids and Caveolin-1 in Tumor Necrosis Factor Alpha-induced Endothelial Cell Activation Metabolism: Clinical and Experimental. Oct, 2008 | Pubmed ID: 18803934 Coplanar Polychlorinated Biphenyl-induced CYP1A1 is Regulated Through Caveolae Signaling in Vascular Endothelial Cells Chemico-biological Interactions. Nov, 2008 | Pubmed ID: 18786521 PPARalpha and PPARgamma Effectively Protect Against HIV-induced Inflammatory Responses in Brain Endothelial Cells Journal of Neurochemistry. Oct, 2008 | Pubmed ID: 18710415 Benzo[a]pyrene Induces Intercellular Adhesion Molecule-1 Through a Caveolae and Aryl Hydrocarbon Receptor Mediated Pathway Toxicology and Applied Pharmacology. Oct, 2008 | Pubmed ID: 18671994 Caveolin-1 Regulates Human Immunodeficiency Virus-1 Tat-induced Alterations of Tight Junction Protein Expression Via Modulation of the Ras Signaling The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2008 | Pubmed ID: 18667611 Pcbs and Tight Junction Expression Environmental Toxicology and Pharmacology. Mar, 2008 | Pubmed ID: 18438464 ORAL ADMINISTRATION OF PCBs INDUCES PROINFLAMMATORY AND PROMETASTATIC RESPONSES Environmental Toxicology and Pharmacology. Mar, 2008 | Pubmed ID: 18438459 Simvastatin Protects Against Amyloid Beta and HIV-1 Tat-induced Promoter Activities of Inflammatory Genes in Brain Endothelial Cells Molecular Pharmacology. May, 2008 | Pubmed ID: 18276775 Changing Ratios of Omega-6 to Omega-3 Fatty Acids Can Differentially Modulate Polychlorinated Biphenyl Toxicity in Endothelial Cells Chemico-biological Interactions. Mar, 2008 | Pubmed ID: 18155686 Limited Role of COX-2 in HIV Tat-induced Alterations of Tight Junction Protein Expression and Disruption of the Blood-brain Barrier Brain Research. Dec, 2007 | Pubmed ID: 17976544 PPARalpha Ligands Reduce PCB-induced Endothelial Activation: Possible Interactions in Inflammation and Atherosclerosis Cardiovascular Toxicology. 2007 | Pubmed ID: 17955387 Zinc Deficiency Alters Lipid Metabolism in LDL Receptor Deficient Mice Treated with Rosiglitazone The Journal of Nutrition. Nov, 2007 | Pubmed ID: 17951467 The Role of Caveolin-1 in PCB77-induced ENOS Phosphorylation in Human-derived Endothelial Cells American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2007 | Pubmed ID: 17933968 Environmental Toxicity, Nutrition, and Gene Interactions in the Development of Atherosclerosis Nutrition, Metabolism, and Cardiovascular Diseases : NMCD. Feb, 2007 | Pubmed ID: 17306736 The NMDA and AMPA/KA Receptors Are Involved in Glutamate-induced Alterations of Occludin Expression and Phosphorylation in Brain Endothelial Cells Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2007 | Pubmed ID: 17245419 ERK 1/2 Signaling Pathway is Involved in Nicotine-mediated Neuroprotection in Spinal Cord Neurons Journal of Cellular Biochemistry. Feb, 2007 | Pubmed ID: 16888810 Interplay Between Epidermal Growth Factor Receptor and Janus Kinase 3 Regulates Polychlorinated Biphenyl-induced Matrix Metalloproteinase-3 Expression and Transendothelial Migration of Tumor Cells Molecular Cancer Research : MCR. Jun, 2006 | Pubmed ID: 16778083 Cyclooxygenase-2 is Involved in HIV-1 Tat-induced Inflammatory Responses in the Brain Neuromolecular Medicine. 2006 | Pubmed ID: 16775385 C-Src is the Primary Signaling Mediator of Polychlorinated Biphenyl-induced Interleukin-8 Expression in a Human Microvascular Endothelial Cell Line Toxicological Sciences : an Official Journal of the Society of Toxicology. Jul, 2006 | Pubmed ID: 16611624 Linoleic Acid Induces Proinflammatory Events in Vascular Endothelial Cells Via Activation of PI3K/Akt and ERK1/2 Signaling The Journal of Nutritional Biochemistry. Nov, 2006 | Pubmed ID: 16563718 HIV-TAT Protein Upregulates Expression of Multidrug Resistance Protein 1 in the Blood-brain Barrier Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2006 | Pubmed ID: 16395283 Zinc Deficiency Increases Plasma Lipids and Atherosclerotic Markers in LDL-receptor-deficient Mice The Journal of Nutrition. Sep, 2005 | Pubmed ID: 16140885 Modification of Environmental Toxicity by Nutrients: Implications in Atherosclerosis Cardiovascular Toxicology. 2005 | Pubmed ID: 16046791 Mechanisms of the Blood-brain Barrier Disruption in HIV-1 Infection Cellular and Molecular Neurobiology. Feb, 2005 | Pubmed ID: 15962513 HIV-Tat Protein Induces P-glycoprotein Expression in Brain Microvascular Endothelial Cells Journal of Neurochemistry. Jun, 2005 | Pubmed ID: 15934943 HIV-1 Tat Protein-induced Alterations of ZO-1 Expression Are Mediated by Redox-regulated ERK 1/2 Activation Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Oct, 2005 | Pubmed ID: 15829913 Signaling Mechanisms of HIV-1 Tat-induced Alterations of Claudin-5 Expression in Brain Endothelial Cells Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Sep, 2005 | Pubmed ID: 15815581 Nicotine Attenuates Morphological Deficits in a Contusion Model of Spinal Cord Injury Journal of Neurotrauma. Feb, 2005 | Pubmed ID: 15716630 Dietary Fat Interacts with PCBs to Induce Changes in Lipid Metabolism in Mice Deficient in Low-density Lipoprotein Receptor Environmental Health Perspectives. Jan, 2005 | Pubmed ID: 15626652 Proinflammatory Synergism of Ethanol and HIV-1 Tat Protein in Brain Tissue Experimental Neurology. Jan, 2005 | Pubmed ID: 15589507 Gene Expression Profile in Interleukin-4-stimulated Human Vascular Endothelial Cells Molecular Medicine (Cambridge, Mass.). Jan-Jun, 2004 | Pubmed ID: 15502879 Arachidonic Acid Increases Choline Acetyltransferase Activity in Spinal Cord Neurons Through a Protein Kinase C-mediated Mechanism Journal of Neurochemistry. Aug, 2004 | Pubmed ID: 15255940 Peroxisome Proliferator Activated Receptors Alpha and Gamma Require Zinc for Their Anti-inflammatory Properties in Porcine Vascular Endothelial Cells The Journal of Nutrition. Jul, 2004 | Pubmed ID: 15226458 Estrogen-mediated Protection Against HIV Tat Protein-induced Inflammatory Pathways in Human Vascular Endothelial Cells Cardiovascular Research. Jul, 2004 | Pubmed ID: 15194470 VEGF Regulates PCB 104-mediated Stimulation of Permeability and Transmigration of Breast Cancer Cells in Human Microvascular Endothelial Cells Experimental Cell Research. Jun, 2004 | Pubmed ID: 15149853 Nicotine Attenuates Oxidative Stress, Activation of Redox-regulated Transcription Factors and Induction of Proinflammatory Genes in Compressive Spinal Cord Trauma Brain Research. Molecular Brain Research. May, 2004 | Pubmed ID: 15135227 Emerging Issues: Nutritional Awareness in Environmental Toxicology The Journal of Nutritional Biochemistry. Apr, 2004 | Pubmed ID: 15068811 Quercetin Protects Against Linoleic Acid-induced Porcine Endothelial Cell Dysfunction The Journal of Nutrition. Apr, 2004 | Pubmed ID: 15051824 Linoleic Acid-induced Endothelial Activation: Role of Calcium and Peroxynitrite Signaling Journal of Lipid Research. May, 2004 | Pubmed ID: 14993245 Involvement of CYP 2C9 in Mediating the Proinflammatory Effects of Linoleic Acid in Vascular Endothelial Cells Journal of the American College of Nutrition. Dec, 2003 | Pubmed ID: 14684755 Apoptosis of Spinal Cord Neurons by Preventing Depletion Nicotine Attenuates Arachidonic Acid-induced of Neurotrophic Factors Journal of Neurotrauma. Nov, 2003 | Pubmed ID: 14651807 Nicotine Upregulates Nerve Growth Factor Expression and Prevents Apoptosis of Cultured Spinal Cord Neurons Neuroscience Research. Nov, 2003 | Pubmed ID: 14568117 HIV-1 Tat Protein Upregulates Inflammatory Mediators and Induces Monocyte Invasion into the Brain Molecular and Cellular Neurosciences. Sep, 2003 | Pubmed ID: 14550782 Zinc Modulates PPARgamma Signaling and Activation of Porcine Endothelial Cells The Journal of Nutrition. Oct, 2003 | Pubmed ID: 14519784 HIV-1 Tat Protein Alters Tight Junction Protein Expression and Distribution in Cultured Brain Endothelial Cells Journal of Neuroscience Research. Oct, 2003 | Pubmed ID: 14515355 Dietary Flavonoids Modulate PCB-induced Oxidative Stress, CYP1A1 Induction, and AhR-DNA Binding Activity in Vascular Endothelial Cells Toxicological Sciences : an Official Journal of the Society of Toxicology. Nov, 2003 | Pubmed ID: 12970578 PCB 104-induced Proinflammatory Reactions in Human Vascular Endothelial Cells: Relationship to Cancer Metastasis and Atherogenesis Toxicological Sciences : an Official Journal of the Society of Toxicology. Sep, 2003 | Pubmed ID: 12805654 2,2',4,6,6'-pentachlorobiphenyl (PCB 104) Induces Apoptosis of Human Microvascular Endothelial Cells Through the Caspase-dependent Activation of CREB Toxicology and Applied Pharmacology. May, 2003 | Pubmed ID: 12758055 Cholesterol Attenuates Linoleic Acid-induced Endothelial Cell Activation Metabolism: Clinical and Experimental. Apr, 2003 | Pubmed ID: 12701065 Methamphetamine Potentiates HIV-1 Tat Protein-mediated Activation of Redox-sensitive Pathways in Discrete Regions of the Brain Experimental Neurology. Jan, 2003 | Pubmed ID: 12504868 HIV-Tat Protein Induces Oxidative and Inflammatory Pathways in Brain Endothelium Journal of Neurochemistry. Jan, 2003 | Pubmed ID: 12485413 Redox-regulated Mechanisms of IL-4-induced MCP-1 Expression in Human Vascular Endothelial Cells American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2003 | Pubmed ID: 12388243 Methamphetamine Activates DNA Binding of Specific Redox-responsive Transcription Factors in Mouse Brain Journal of Neuroscience Research. Oct, 2002 | Pubmed ID: 12237866 Methamphetamine-induced TNF-alpha Gene Expression and Activation of AP-1 in Discrete Regions of Mouse Brain: Potential Role of Reactive Oxygen Intermediates and Lipid Peroxidation Neuromolecular Medicine. 2002 | Pubmed ID: 12230306 Measurement of Inflammatory Properties of Fatty Acids in Human Endothelial Cells Methods in Enzymology. 2002 | Pubmed ID: 12125348 Proinflammatory Properties of Coplanar PCBs: in Vitro and in Vivo Evidence Toxicology and Applied Pharmacology. Jun, 2002 | Pubmed ID: 12079426 PCB-induced Oxidative Stress in Endothelial Cells: Modulation by Nutrients International Journal of Hygiene and Environmental Health. Mar, 2002 | Pubmed ID: 12018021 Unsaturated Fatty Acids Selectively Induce an Inflammatory Environment in Human Endothelial Cells The American Journal of Clinical Nutrition. Jan, 2002 | Pubmed ID: 11756069 Linoleic Acid Induces MCP-1 Gene Expression in Human Microvascular Endothelial Cells Through an Oxidative Mechanism The Journal of Nutritional Biochemistry. Nov, 2001 | Pubmed ID: 12031258 En trippel primær cellekulturmodell av den menneskelige blod-hjernebarrieren for å studere iskemisk hjerneslag in vitro Nikolai Fattakhov1, Silvia Torices1, Sarah Becker1, Timea Teglas1, Oandy Naranjo1, Michal Toborek1,2 1Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, 2Institute of Physiotherapy and Health Sciences, The Jerzy Kukuczka Academy of Physical Education JoVE 64469 Biochimica Induksjon av hjerneinfarkt og iskemi-reperfusjon i Mus Bruke Midt arterieokklusjon Teknikk og visualisering av Infarkt området Luc Bertrand1,2, Levi Dygert2, Michal Toborek1,3 1Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, 2Miller School of Medicine, University of Miami, 3Jerzy Kukuczka Academy of Physical Education Medicina Mus Microsurgery Infusion Teknikk for målrettet Stoff Levering inn i CNS Ana R. Leda1, Levy Dygert1, Luc Bertrand1, Michal Toborek1,2 1Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, 2The Jerzy Kukuczka Academy of Physical Education Neuroscienze
En trippel primær cellekulturmodell av den menneskelige blod-hjernebarrieren for å studere iskemisk hjerneslag in vitro Nikolai Fattakhov1, Silvia Torices1, Sarah Becker1, Timea Teglas1, Oandy Naranjo1, Michal Toborek1,2 1Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, 2Institute of Physiotherapy and Health Sciences, The Jerzy Kukuczka Academy of Physical Education JoVE 64469 Biochimica
Induksjon av hjerneinfarkt og iskemi-reperfusjon i Mus Bruke Midt arterieokklusjon Teknikk og visualisering av Infarkt området Luc Bertrand1,2, Levi Dygert2, Michal Toborek1,3 1Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, 2Miller School of Medicine, University of Miami, 3Jerzy Kukuczka Academy of Physical Education Medicina
Mus Microsurgery Infusion Teknikk for målrettet Stoff Levering inn i CNS Ana R. Leda1, Levy Dygert1, Luc Bertrand1, Michal Toborek1,2 1Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, 2The Jerzy Kukuczka Academy of Physical Education Neuroscienze