Ming Lei Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research Southwest Medical University Biography Publications Institution JoVE Articles Ming Lei has not added a biography. If you are Ming Lei and would like to personalize this page please email our Author Liaison for assistance. Publications Mechanosensitive Channels TMEM63A and TMEM63B Mediate Lung Inflation-induced Surfactant Secretion The Journal of Clinical Investigation. Dec, 2023 | Pubmed ID: 38127458 Dbh Catecholaminergic Cardiomyocytes Contribute to the Structure and Function of the Cardiac Conduction System in Murine Heart Nature Communications. Nov, 2023 | Pubmed ID: 38016975 Single-cell RNA Sequencing of Murine Hearts for Studying the Development of the Cardiac Conduction System Scientific Data. Sep, 2023 | Pubmed ID: 37666871 The Novel Peptide Athycaltide-1 Attenuates Ang II-induced Pathological Myocardial Hypertrophy by Reducing ROS and Inhibiting the Activation of CaMKII and ERK1/2 European Journal of Pharmacology. Oct, 2023 | Pubmed ID: 37567457 Editorial: Cardiovascular Remodeling Frontiers in Pharmacology. 2023 | Pubmed ID: 37554980 Phenome-wide Association Study and Precision Medicine of Cardiovascular Diseases in the Post-COVID-19 Era Acta Pharmacologica Sinica. Dec, 2023 | Pubmed ID: 37532784 Generation of Cardiomyocytes from Human-induced Pluripotent Stem Cells Resembling Atrial Cells with Ability to Respond to Adrenoceptor Agonists Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Jun, 2023 | Pubmed ID: 37122218 Cardiac Deficiency of P21-activated Kinase 1 Promotes Atrial Arrhythmogenesis in Mice Following Adrenergic Challenge Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Jun, 2023 | Pubmed ID: 37122217 Various Fractions of Alcoholic Extracts from Functionalized Antioxidation and Antiaging in D-Galactose-Induced Aging Mice Frontiers in Bioscience (Landmark Edition). Nov, 2022 | Pubmed ID: 36472113 Exploration of Interaction Property Between Nonylphenol and G Protein-coupled Receptor 30 Based on Molecular Simulation and Biological Experiments Steroids. Dec, 2022 | Pubmed ID: 36154832 High-Resolution 3D Heart Models of Cardiomyocyte Subpopulations in Cleared Murine Heart Frontiers in Physiology. 2022 | Pubmed ID: 35665220 Neuropilin-1 is a Valuable Biomarker for Predicting Response of Advanced Non-small Cell Lung Cancer Patients to Hypofractionated Radiotherapy and PD-1 Blockade International Immunopharmacology. Aug, 2022 | Pubmed ID: 35468364 Ageing Increases Cardiac Electrical Remodelling in Rats and Mice Via NOX4/ROS/CaMKII-Mediated Calcium Signalling Oxidative Medicine and Cellular Longevity. 2022 | Pubmed ID: 35387264 Ventricular SK2 Upregulation Following Angiotensin II Challenge: Modulation by P21-activated Kinase-1 Journal of Molecular and Cellular Cardiology. Mar, 2022 | Pubmed ID: 34774547 A Dataset of Dual Calcium and Voltage Optical Mapping in Healthy and Hypertrophied Murine Hearts Scientific Data. Dec, 2021 | Pubmed ID: 34916511 A Comparative Study of Systolic and Diastolic Mechanical Synchrony in Canine, Primate, and Healthy and Failing Human Hearts Frontiers in Cardiovascular Medicine. 2021 | Pubmed ID: 34778406 Electrophysiological and Proarrhythmic Effects of Hydroxychloroquine Challenge in Guinea-Pig Hearts ACS Pharmacology & Translational Science. Oct, 2021 | Pubmed ID: 34661080 Generation of Induced Pluripotent Stem Cells (iPSCs) from a Chinese Infant (XACHi015-A) with Type 2 Long QT Syndrome Carrying the Heterozygous Mutation C.1814C>T(p.P605L) in KCNH2 Stem Cell Research. Oct, 2021 | Pubmed ID: 34438161 Establishment of IPSC Line from a Chinese Infant (XACHi012-A) with Jervell and Lange-Nielsen Syndrome Carrying Combined KCNQ1 Frameshift C.431delC(p.I145Sfs*92) and Nonsense C.1175G > A (p.W392X) Variants and Two IPSC Lines from the Parents (XACHi013-A, XACHi014-A) Stem Cell Research. May, 2021 | Pubmed ID: 34088017 Novel Cardiac Cell Subpopulations: Pnmt-derived Cardiomyocytes Open Biology. Aug, 2020 | Pubmed ID: 32810421 Generation of Two Induced Pluripotent Stem Cell Lines (XACHi0010-A, XACHi0011-A) from a Chinese Family with Combined Oxidative Phosphorylation Deficiency Carrying Homozygous and Heterozygous C1QBP-L275F Mutation Stem Cell Research. Jul, 2020 | Pubmed ID: 32707487 Editorial: Optogenetics: An Emerging Approach in Cardiac Electrophysiology Frontiers in Physiology. 2020 | Pubmed ID: 32411019 Generation of Three IPSC Lines (XACHi007-A, XACHi008-A, XACHi009-A) from a Chinese Family with Long QT Syndrome Type 5 with Heterozygous C.226G>A (p.D76N) Mutation in KCNE1gene Stem Cell Research. May, 2020 | Pubmed ID: 32344329 Distinct Roles of Calmodulin and Ca/calmodulin-dependent Protein Kinase II in Isopreterenol-induced Cardiac Hypertrophy Biochemical and Biophysical Research Communications. Jun, 2020 | Pubmed ID: 32303334 A Potent Antiarrhythmic Drug N-methyl Berbamine Extends the Action Potential Through Inhibiting Both Calcium and Potassium Currents Journal of Pharmacological Sciences. Apr, 2020 | Pubmed ID: 31992491 Update on Antiarrhythmic Drug Pharmacology Journal of Cardiovascular Electrophysiology. Feb, 2020 | Pubmed ID: 31930579 Cardiac Arrhythmogenesis: a Tale of Two Clocks? Cardiovascular Research. Dec, 2020 | Pubmed ID: 31800017 A Protocol for Dual Calcium-Voltage Optical Mapping in Murine Sinoatrial Preparation With Optogenetic Pacing Frontiers in Physiology. 2019 | Pubmed ID: 31456689 Pnmt-Derived Cardiomyocytes: Anatomical Localization, Function and Future Perspectives Frontiers in Physiology. 2019 | Pubmed ID: 31354504 Response by Lei Et Al to Letter Regarding Article, "Modernized Classification of Cardiac Antiarrhythmic Drugs" Circulation. Mar, 2019 | Pubmed ID: 30908105 Biochemical Studies of Membrane Fusion at the Single-particle Level Progress in Lipid Research. Jan, 2019 | Pubmed ID: 30611882 Modernized Classification of Cardiac Antiarrhythmic Drugs Circulation. Oct, 2018 | Pubmed ID: 30354657 Late Sodium Current Associated Cardiac Electrophysiological and Mechanical Dysfunction Pflugers Archiv : European Journal of Physiology. Mar, 2018 | Pubmed ID: 29127493 Three-dimensional Image Reconstruction of Distribution of Pnmt Cell-derived Cells in Murine Heart Scientific Data. Sep, 2017 | Pubmed ID: 28949324 Effect of Sphingosine-1-phosphate on L-type Calcium Current and Ca(2+) Transient in Rat Ventricular Myocytes Molecular and Cellular Biochemistry. Aug, 2016 | Pubmed ID: 27372350 Pak1 is Required to Maintain Ventricular Ca²⁺ Homeostasis and Electrophysiological Stability Through SERCA2a Regulation in Mice Circulation. Arrhythmia and Electrophysiology. Oct, 2014 | Pubmed ID: 25217043 儿茶酚胺能多形性室性心动过速的 RyR2R2474S 敲入小鼠心脏的双染料光学映射 Yangpeng Li*1,2, Jun Yang*1, Rui Zhang1, Tangting Chen1, Shiyu Zhang1, Yuqing Zheng1, Qiang Wen3, Tao Li1, Xiaoqiu Tan1,2, Ming Lei1,4, Xianhong Ou1 1Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research, Southwest Medical University, 2Department of Cardiology, the Affiliated Hospital of Southwest Medical University, 3Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 4Department of Pharmacology, University of Oxford JoVE 65082 Biologia
儿茶酚胺能多形性室性心动过速的 RyR2R2474S 敲入小鼠心脏的双染料光学映射 Yangpeng Li*1,2, Jun Yang*1, Rui Zhang1, Tangting Chen1, Shiyu Zhang1, Yuqing Zheng1, Qiang Wen3, Tao Li1, Xiaoqiu Tan1,2, Ming Lei1,4, Xianhong Ou1 1Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research, Southwest Medical University, 2Department of Cardiology, the Affiliated Hospital of Southwest Medical University, 3Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 4Department of Pharmacology, University of Oxford JoVE 65082 Biologia