Natalia A. Trayanova Institute for Computational Medicine and the Department of Biomedical Engineering Johns Hopkins University Biography Publications Institution JoVE Articles Natalia A. Trayanova has not added a biography. If you are Natalia A. Trayanova and would like to personalize this page please email our Author Liaison for assistance. Publications Computational Cardiology: the Heart of the Matter ISRN Cardiology. 2012 | Pubmed ID: 23213566 Mechanisms Underlying Isovolumic Contraction and Ejection Peaks in Seismocardiogram Morphology Journal of Medical and Biological Engineering. 2012 | Pubmed ID: 23105942 Computational Cardiology: How Computer Simulations Could Be Used to Develop New Therapies and Advance Existing Ones Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. Nov, 2012 | Pubmed ID: 23104919 Mechanisms of Human Atrial Fibrillation Initiation: Clinical and Computational Studies of Repolarization Restitution and Activation Latency Circulation. Arrhythmia and Electrophysiology. Dec, 2012 | Pubmed ID: 23027797 Methodology for Patient-specific Modeling of Atrial Fibrosis As a Substrate for Atrial Fibrillation Journal of Electrocardiology. Nov-Dec, 2012 | Pubmed ID: 22999492 Progress in Biophysics and Molecular Biology. Oct-Nov, 2012 | Pubmed ID: 22884712 Three-dimensional Mechanisms of Increased Vulnerability to Electric Shocks in Myocardial Infarction: Altered Virtual Electrode Polarizations and Conduction Delay in the Peri-infarct Zone The Journal of Physiology. Sep, 2012 | Pubmed ID: 22586222 The Role of Fibroblasts in Complex Fractionated Electrograms During Persistent/permanent Atrial Fibrillation: Implications for Electrogram-based Catheter Ablation Circulation Research. Jan, 2012 | Pubmed ID: 22179057 Comparison of the Effects of Continuous and Pulsatile Left Ventricular-assist Devices on Ventricular Unloading Using a Cardiac Electromechanics Model The Journal of Physiological Sciences : JPS. Jan, 2012 | Pubmed ID: 22076841 A Novel Methodology for Assessing the Bounded-input Bounded-output Instability in QT Interval Dynamics: Application to Clinical ECG with Ventricular Tachycardia IEEE Transactions on Bio-medical Engineering. Aug, 2012 | Pubmed ID: 21984490 Reversible Cardiac Conduction Block and Defibrillation with High-frequency Electric Field Science Translational Medicine. Sep, 2011 | Pubmed ID: 21957174 Susceptibility to Arrhythmia in the Infarcted Heart Depends on Myofibroblast Density Biophysical Journal. Sep, 2011 | Pubmed ID: 21943411 Cardiac Electromechanical Models: from Cell to Organ Frontiers in Physiology. 2011 | Pubmed ID: 21886622 A Computational Model to Predict the Effects of Class I Anti-arrhythmic Drugs on Ventricular Rhythms Science Translational Medicine. Aug, 2011 | Pubmed ID: 21885405 Unstable QT Interval Dynamics Precedes Ventricular Tachycardia Onset in Patients with Acute Myocardial Infarction: a Novel Approach to Detect Instability in QT Interval Dynamics from Clinical ECG Circulation. Arrhythmia and Electrophysiology. Dec, 2011 | Pubmed ID: 21841208 Electromechanical Models of the Ventricles American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2011 | Pubmed ID: 21572017 IEEE Transactions on Bio-medical Engineering. Jun, 2011 | Pubmed ID: 21335301 Whole-heart Modeling: Applications to Cardiac Electrophysiology and Electromechanics Circulation Research. Jan, 2011 | Pubmed ID: 21212393 Models of Cardiac Electromechanics Based on Individual Hearts Imaging Data: Image-based Electromechanical Models of the Heart Biomechanics and Modeling in Mechanobiology. Jun, 2011 | Pubmed ID: 20589408 Sudden Cardiac Death Prediction and Prevention: Report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop Circulation. Nov, 2010 | Pubmed ID: 21147730 Models of Stretch-activated Ventricular Arrhythmias Journal of Electrocardiology. Nov-Dec, 2010 | Pubmed ID: 20638670 Rate-dependent Action Potential Alternans in Human Heart Failure Implicates Abnormal Intracellular Calcium Handling Heart Rhythm : the Official Journal of the Heart Rhythm Society. Aug, 2010 | Pubmed ID: 20382266 Tunnel Propagation Following Defibrillation with ICD Shocks: Hidden Postshock Activations in the Left Ventricular Wall Underlie Isoelectric Window Heart Rhythm : the Official Journal of the Heart Rhythm Society. Jul, 2010 | Pubmed ID: 20348028 Mechanisms for Initiation of Reentry in Acute Regional Ischemia Phase 1B Heart Rhythm : the Official Journal of the Heart Rhythm Society. Mar, 2010 | Pubmed ID: 20097623 Integrative Computational Models of Cardiac Arrhythmias -- Simulating the Structurally Realistic Heart Drug Discovery Today. Disease Models. 2009 | Pubmed ID: 20628585 Electrotonic Coupling Between Human Atrial Myocytes and Fibroblasts Alters Myocyte Excitability and Repolarization Biophysical Journal. Oct, 2009 | Pubmed ID: 19843450 K+ Current Changes Account for the Rate Dependence of the Action Potential in the Human Atrial Myocyte American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2009 | Pubmed ID: 19633207 Automatically Generated, Anatomically Accurate Meshes for Cardiac Electrophysiology Problems IEEE Transactions on Bio-medical Engineering. May, 2009 | Pubmed ID: 19203877 Mathematical Simulations of Ligand-gated and Cell-type Specific Effects on the Action Potential of Human Atrium Progress in Biophysics and Molecular Biology. Oct-Nov, 2008 | Pubmed ID: 19186188 Action Potential Dynamics Explain Arrhythmic Vulnerability in Human Heart Failure: a Clinical and Modeling Study Implicating Abnormal Calcium Handling Journal of the American College of Cardiology. Nov, 2008 | Pubmed ID: 19022157 Systems Approach to Understanding Electromechanical Activity in the Human Heart: a National Heart, Lung, and Blood Institute Workshop Summary Circulation. Sep, 2008 | Pubmed ID: 18779456 From Mitochondrial Ion Channels to Arrhythmias in the Heart: Computational Techniques to Bridge the Spatio-temporal Scales Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences. Sep, 2008 | Pubmed ID: 18603526 The Long and the Short of Long and Short Duration Ventricular Fibrillation Circulation Research. May, 2008 | Pubmed ID: 18497314 The Role of Mechanoelectric Feedback in Vulnerability to Electric Shock Progress in Biophysics and Molecular Biology. Jun-Jul, 2008 | Pubmed ID: 18374394 Tunnel Propagation of Postshock Activations As a Hypothesis for Fibrillation Induction and Isoelectric Window Circulation Research. Mar, 2008 | Pubmed ID: 18218982 Photon Scattering Effects in Optical Mapping of Propagation and Arrhythmogenesis in the Heart Journal of Electrocardiology. Nov-Dec, 2007 | Pubmed ID: 17993334 The Role of Photon Scattering in Optical Signal Distortion During Arrhythmia and Defibrillation Biophysical Journal. Nov, 2007 | Pubmed ID: 17978166 Somato-dendritic Mechanisms Underlying the Electrophysiological Properties of Hypothalamic Magnocellular Neuroendocrine Cells: a Multicompartmental Model Study Journal of Computational Neuroscience. Oct, 2007 | Pubmed ID: 17484044 Maintenance of Ventricular Fibrillation in Heterogeneous Ventricle Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2006 | Pubmed ID: 17947061 Cardiac Defibrillation and the Role of Mechanoelectric Feedback in Postshock Arrhythmogenesis Annals of the New York Academy of Sciences. Oct, 2006 | Pubmed ID: 17132792 Action Potential Morphology Heterogeneity in the Atrium and Its Effect on Atrial Reentry: a Two-dimensional and Quasi-three-dimensional Study Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences. Jun, 2006 | Pubmed ID: 16766349 Mechanistic Enquiry into the Effect of Increased Pacing Rate on the Upper Limit of Vulnerability Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences. Jun, 2006 | Pubmed ID: 16766348 Characterization of the Relationship Between Preshock State and Virtual Electrode Polarization-induced Propagated Graded Responses Resulting in Arrhythmia Induction Heart Rhythm : the Official Journal of the Heart Rhythm Society. May, 2006 | Pubmed ID: 16648066 Cell and Tissue Responses to Electric Shocks Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. Sep, 2005 | Pubmed ID: 16102513 Differences Between Left and Right Ventricular Chamber Geometry Affect Cardiac Vulnerability to Electric Shocks Circulation Research. Jul, 2005 | Pubmed ID: 15976315 Asymmetry in Membrane Responses to Electric Shocks: Insights from Bidomain Simulations Biophysical Journal. Oct, 2004 | Pubmed ID: 15454429 Mechanistic Inquiry into Decrease in Probability of Defibrillation Success with Increase in Complexity of Preshock Reentrant Activity American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2004 | Pubmed ID: 14604852 Postshock Arrhythmogenesis in a Slice of the Canine Heart Journal of Cardiovascular Electrophysiology. Oct, 2003 | Pubmed ID: 14760930 Virtual Electrode-induced Positive and Negative Graded Responses: New Insights into Fibrillation Induction and Defibrillation Journal of Cardiovascular Electrophysiology. Jul, 2003 | Pubmed ID: 12930258 Termination of Reentry by a Long-lasting AC Shock in a Slice of Canine Heart: a Computational Study Journal of Cardiovascular Electrophysiology. Dec, 2002 | Pubmed ID: 12521342 Are We Closer to Understanding Defibrillation in the Whole Heart? Journal of Cardiovascular Electrophysiology. Nov, 2002 | Pubmed ID: 12475104 Computational Techniques for Solving the Bidomain Equations in Three Dimensions IEEE Transactions on Bio-medical Engineering. Nov, 2002 | Pubmed ID: 12450356 Patiënt-specifieke modellering van het Hart: Schatting van ventriculaire vezeloriëntaties Fijoy Vadakkumpadan1, Hermenegild Arevalo1, Natalia A. Trayanova1 1Institute for Computational Medicine and the Department of Biomedical Engineering, Johns Hopkins University JoVE 50125 Bioingegneria
Patiënt-specifieke modellering van het Hart: Schatting van ventriculaire vezeloriëntaties Fijoy Vadakkumpadan1, Hermenegild Arevalo1, Natalia A. Trayanova1 1Institute for Computational Medicine and the Department of Biomedical Engineering, Johns Hopkins University JoVE 50125 Bioingegneria