Ole S. Søgaard Department of Clinical Medicine Aarhus University Biography Publications Institution JoVE Articles Ole S. Søgaard has not added a biography. If you are Ole S. Søgaard and would like to personalize this page please email our Author Liaison for assistance. Publications Fimepinostat, a Novel Dual Inhibitor of HDAC and PI3K, Effectively Reverses HIV-1 Latency Without T Cell Activation Journal of Virus Eradication. Sep, 2019 | Pubmed ID: 31700656 Fimepinostat, a Novel Dual Inhibitor of HDAC and PI3K, Effectively Reverses HIV-1 Latency Without T Cell Activation Journal of Virus Eradication. Sep, 2019 | Pubmed ID: 31700655 Impacts of HIV Cure Interventions on Viral Reservoirs in Tissues Frontiers in Microbiology. 2019 | Pubmed ID: 31497010 TLR9 Agonist MGN1703 Enhances B Cell Differentiation and Function in Lymph Nodes EBioMedicine. Jul, 2019 | Pubmed ID: 31300344 DC-based Immunotherapy As Strategy to Purge the HIV Reservoir? EBioMedicine. May, 2019 | Pubmed ID: 30981650 Effects of 24-week Toll-like Receptor 9 Agonist Treatment in HIV Type 1+ Individuals AIDS (London, England). 07, 2019 | Pubmed ID: 30932955 Recommendations for Analytical Antiretroviral Treatment Interruptions in HIV Research Trials-report of a Consensus Meeting The Lancet. HIV. Apr, 2019 | Pubmed ID: 30885693 In-vivo Administration of Histone Deacetylase Inhibitors Does Not Impair Natural Killer Cell Function in HIV+ Individuals AIDS (London, England). 03, 2019 | Pubmed ID: 30830886 Characterization of Intact Proviruses in Blood and Lymph Node from HIV-Infected Individuals Undergoing Analytical Treatment Interruption Journal of Virology. 04, 2019 | Pubmed ID: 30700598 Characterization of the HIV-1 Transcription Profile After Romidepsin Administration in ART-suppressed Individuals AIDS (London, England). 03, 2019 | Pubmed ID: 30531314 Clinical Interventions in HIV Cure Research Advances in Experimental Medicine and Biology. 2018 | Pubmed ID: 30030798 Differences in Antiretroviral Regimens Do Not Impact Safety or Level of Latency Reversal in Persons Receiving Romidepsin AIDS (London, England). 07, 2018 | Pubmed ID: 30001247 Genetic Characterization of the HIV-1 Reservoir After Vacc-4x and Romidepsin Therapy in HIV-1-infected Individuals AIDS (London, England). 08, 2018 | Pubmed ID: 29762162 Cellular Immunogenicity of Human Papillomavirus Vaccines Cervarix and Gardasil in Adults with HIV Infection Human Vaccines & Immunotherapeutics. 04, 2018 | Pubmed ID: 29172992 Estimating Initial Viral Levels During Simian Immunodeficiency Virus/Human Immunodeficiency Virus Reactivation from Latency Journal of Virology. 01, 2018 | Pubmed ID: 29118123 The TLR9 Agonist MGN1703 Triggers a Potent Type I Interferon Response in the Sigmoid Colon Mucosal Immunology. Mar, 2018 | Pubmed ID: 28766555 HDAC Inhibition Induces HIV-1 Protein and Enables Immune-based Clearance Following Latency Reversal JCI Insight. Aug, 2017 | Pubmed ID: 28814661 Anti-HIV-1 ADCC Antibodies Following Latency Reversal and Treatment Interruption Journal of Virology. 08, 2017 | Pubmed ID: 28539449 Beyond Antiretroviral Therapy: Early Interventions to Control HIV-1 Infection AIDS (London, England). 07, 2017 | Pubmed ID: 28463884 Short-Course Toll-Like Receptor 9 Agonist Treatment Impacts Innate Immunity and Plasma Viremia in Individuals With Human Immunodeficiency Virus Infection Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Jun, 2017 | Pubmed ID: 28329286 Romidepsin-induced HIV-1 Viremia During Effective Antiretroviral Therapy Contains Identical Viral Sequences with Few Deleterious Mutations AIDS (London, England). 03, 2017 | Pubmed ID: 28272134 Modeling of Experimental Data Supports HIV Reactivation from Latency After Treatment Interruption on Average Once Every 5-8 Days PLoS Pathogens. 08, 2016 | Pubmed ID: 27560972 Immune Checkpoints and the HIV-1 Reservoir: Proceed with Caution Journal of Virus Eradication. Jul, 2016 | Pubmed ID: 27482460 Using Animal Models to Overcome Temporal, Spatial and Combinatorial Challenges in HIV Persistence Research Journal of Translational Medicine. Feb, 2016 | Pubmed ID: 26861779 Administration of Panobinostat Is Associated with Increased IL-17A MRNA in the Intestinal Epithelium of HIV-1 Patients Mediators of Inflammation. 2015 | Pubmed ID: 26696749 The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo PLoS Pathogens. Sep, 2015 | Pubmed ID: 26379282 Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline During Latency-Reversing Treatment with Panobinostat Journal of Virology. Oct, 2015 | Pubmed ID: 26223643 Does Pneumococcal Vaccination Prevent Myocardial Infarction and Stroke in Elderly Adults? Open Heart. 2015 | Pubmed ID: 26217544 HIV Reactivation from Latency After Treatment Interruption Occurs on Average Every 5-8 Days--Implications for HIV Remission PLoS Pathogens. Jul, 2015 | Pubmed ID: 26133551 Activation of Latent Human Immunodeficiency Virus by the Histone Deacetylase Inhibitor Panobinostat: a Pilot Study to Assess Effects on the Central Nervous System Open Forum Infectious Diseases. Jan, 2015 | Pubmed ID: 26034779 Histone Deacetylase Inhibitor Romidepsin Inhibits De Novo HIV-1 Infections Antimicrobial Agents and Chemotherapy. Jul, 2015 | Pubmed ID: 25896701 Interleukin-37 Expression Is Increased in Chronic HIV-1-Infected Individuals and Is Associated with Inflammation and the Size of the Total Viral Reservoir Molecular Medicine (Cambridge, Mass.). Apr, 2015 | Pubmed ID: 25879630 Risk and Prognosis of Staphylococcus Aureus Bacteremia Among Individuals with and Without End-stage Renal Disease: a Danish, Population-based Cohort Study BMC Infectious Diseases. Jan, 2015 | Pubmed ID: 25566857 Panobinostat, a Histone Deacetylase Inhibitor, for Latent-virus Reactivation in HIV-infected Patients on Suppressive Antiretroviral Therapy: a Phase 1/2, Single Group, Clinical Trial The Lancet. HIV. Oct, 2014 | Pubmed ID: 26423811 Vaccination Against Oncogenic Human Papillomavirus Infection in HIV-infected Populations: Review of Current Status and Future Perspectives Sexual Health. Dec, 2014 | Pubmed ID: 25218800 Comparison of the Immunogenicity of Cervarix® and Gardasil® Human Papillomavirus Vaccines for Oncogenic Non-vaccine Serotypes HPV-31, HPV-33, and HPV-45 in HIV-infected Adults Human Vaccines & Immunotherapeutics. 2014 | Pubmed ID: 24553190 Comparison of the Immunogenicity and Reactogenicity of Cervarix and Gardasil Human Papillomavirus Vaccines in HIV-infected Adults: a Randomized, Double-blind Clinical Trial The Journal of Infectious Diseases. Apr, 2014 | Pubmed ID: 24273179 Administration of a Toll-like Receptor 9 Agonist Decreases the Proviral Reservoir in Virologically Suppressed HIV-infected Patients PloS One. 2013 | Pubmed ID: 23637967 Eliminating the Latent HIV Reservoir by Reactivation Strategies: Advancing to Clinical Trials Human Vaccines & Immunotherapeutics. Apr, 2013 | Pubmed ID: 23563519 Central Nervous System Infections Among Individuals with and Without End-stage Renal Disease The Journal of Infection. Jul, 2013 | Pubmed ID: 23549040 Use of Population Based Background Rates of Disease to Assess Vaccine Safety in Childhood and Mass Immunisation in Denmark: Nationwide Population Based Cohort Study BMJ (Clinical Research Ed.). Sep, 2012 | Pubmed ID: 22988304 Antiviral and Immunological Effects of Tenofovir Microbicide in Vaginal Herpes Simplex Virus 2 Infection AIDS Research and Human Retroviruses. Nov, 2012 | Pubmed ID: 22867119 The Impact of B-cell Perturbations on Pneumococcal Conjugate Vaccine Response in HIV-infected Adults PloS One. 2012 | Pubmed ID: 22860110 TLR9-adjuvanted Pneumococcal Conjugate Vaccine Induces Antibody-independent Memory Responses in HIV-infected Adults Human Vaccines & Immunotherapeutics. Aug, 2012 | Pubmed ID: 22854665 Risk and Prognosis of Hospitalization for Pneumonia Among Individuals with and Without Functioning Renal Transplants in Denmark: a Population-based Study Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Sep, 2012 | Pubmed ID: 22610926 Morbidity and Risk of Subsequent Diagnosis of HIV: a Population Based Case Control Study Identifying Indicator Diseases for HIV Infection PloS One. 2012 | Pubmed ID: 22403672 Risk Factors for Pneumococcal Nasopharyngeal Colonization Before and After Pneumococcal Conjugate Vaccination in Persons with HIV: Brief Report Current HIV Research. Apr, 2012 | Pubmed ID: 22384845 Timing of Toll-like Receptor 9 Agonist Administration in Pneumococcal Vaccination Impacts Both Humoral and Cellular Immune Responses As Well As Nasopharyngeal Colonization in Mice Infection and Immunity. May, 2012 | Pubmed ID: 22371375 Tenofovir Selectively Regulates Production of Inflammatory Cytokines and Shifts the IL-12/IL-10 Balance in Human Primary Cells Journal of Acquired Immune Deficiency Syndromes (1999). Aug, 2011 | Pubmed ID: 21471820 Intraabdominal and Retroperitoneal Soft-tissue Sarcomas--outcome of Surgical Treatment in Primary and Recurrent Tumors World Journal of Surgical Oncology. Sep, 2010 | Pubmed ID: 20831829 Pneumococcal Conjugate Vaccination in Persons with HIV: the Effect of Highly Active Antiretroviral Therapy AIDS (London, England). Jun, 2010 | Pubmed ID: 20559037 Improving the Immunogenicity of Pneumococcal Conjugate Vaccine in HIV-infected Adults with a Toll-like Receptor 9 Agonist Adjuvant: a Randomized, Controlled Trial Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Jul, 2010 | Pubmed ID: 20504165 Clinical Features and Predictors of Mortality in Admitted Patients with Community- and Hospital-acquired Legionellosis: a Danish Historical Cohort Study BMC Infectious Diseases. May, 2010 | Pubmed ID: 20492639 Transmission of HIV-1 Drug-resistant Variants: Prevalence and Effect on Treatment Outcome Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Feb, 2010 | Pubmed ID: 20085464 Mortality After Hospitalization for Pneumonia Among Individuals with HIV, 1995-2008: a Danish Cohort Study PloS One. Sep, 2009 | Pubmed ID: 19750011 Hospitalization for Pneumonia Among Individuals with and Without HIV Infection, 1995-2007: a Danish Population-based, Nationwide Cohort Study Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Nov, 2008 | Pubmed ID: 18834317 A Binational Cohort Study of Ventilator-associated Pneumonia in Denmark and Australia Scandinavian Journal of Infectious Diseases. 2006 | Pubmed ID: 16715595 Humaniserede NOG-mus til intravaginal hiv-eksponering og behandling af hiv-infektion Anna H. F. Andersen1,2, Stine S. F. Nielsen1,2, Rikke Olesen1,2, Katharina Mack1, Frederik Dagnæs-Hansen3, Niels Uldbjerg1,4, Lars Østergaard1,2, Ole S. Søgaard1,2, Paul W. Denton1,2,5, Martin Tolstrup1,2 1Department of Clinical Medicine, Aarhus University, 2Department of Infectious Diseases, Aarhus University Hospital, 3Department of Biomedicine, Aarhus University, 4Department of Gynecology and Obstetrics, Aarhus University Hospital, 5Department of Biology, University of Nebraska at Omaha JoVE 60723 Immunologia e infezioni
Humaniserede NOG-mus til intravaginal hiv-eksponering og behandling af hiv-infektion Anna H. F. Andersen1,2, Stine S. F. Nielsen1,2, Rikke Olesen1,2, Katharina Mack1, Frederik Dagnæs-Hansen3, Niels Uldbjerg1,4, Lars Østergaard1,2, Ole S. Søgaard1,2, Paul W. Denton1,2,5, Martin Tolstrup1,2 1Department of Clinical Medicine, Aarhus University, 2Department of Infectious Diseases, Aarhus University Hospital, 3Department of Biomedicine, Aarhus University, 4Department of Gynecology and Obstetrics, Aarhus University Hospital, 5Department of Biology, University of Nebraska at Omaha JoVE 60723 Immunologia e infezioni