Owen J.T. McCarty Department of Biomedical Engineering Oregon Health & Science University, School of Medicine Biography Publications Institution JoVE Articles Owen J.T. McCarty has not added a biography. If you are Owen J.T. McCarty and would like to personalize this page please email our Author Liaison for assistance. Publications Measurement Science in the Circulatory System Cellular and Molecular Bioengineering. Mar, 2014 | Pubmed ID: 24563678 Network Signatures of Nuclear and Cytoplasmic Density Alterations in a Model of Pre and Postmetastatic Colorectal Cancer Journal of Biomedical Optics. Jan, 2014 | Pubmed ID: 24441943 Factor XII Inhibition Reduces Thrombus Formation in a Primate Thrombosis Model Blood. Mar, 2014 | Pubmed ID: 24408325 Physical Biology in Cancer. 2. The Physical Biology of Circulating Tumor Cells American Journal of Physiology. Cell Physiology. Jan, 2014 | Pubmed ID: 24133063 A Theme Series on Physical Biology in Cancer in AJP-Cell American Journal of Physiology. Cell Physiology. Jan, 2014 | Pubmed ID: 24067917 Rac and Cdc42 Team Up for Platelets Blood. Oct, 2013 | Pubmed ID: 24178962 Phosphatidylserine Index As a Marker of the Procoagulant Phenotype of Acute Myelogenous Leukemia Cells Physical Biology. Oct, 2013 | Pubmed ID: 24104188 Histone Deacetylase 6-mediated Deacetylation of α-tubulin Coordinates Cytoskeletal and Signaling Events During Platelet Activation American Journal of Physiology. Cell Physiology. Dec, 2013 | Pubmed ID: 24025866 P21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils PloS One. 2013 | Pubmed ID: 24019894 Role of Coagulation in the Recruitment of Colon Adenocarcinoma Cells to Thrombus Under Shear American Journal of Physiology. Cell Physiology. Nov, 2013 | Pubmed ID: 23903698 The PAK System Links Rho GTPase Signaling to Thrombin-mediated Platelet Activation American Journal of Physiology. Cell Physiology. Sep, 2013 | Pubmed ID: 23784547 Pivotal Role for the MTOR Pathway in the Formation of Neutrophil Extracellular Traps Via Regulation of Autophagy American Journal of Physiology. Cell Physiology. Aug, 2013 | Pubmed ID: 23720022 Microfluidics and Coagulation Biology Annual Review of Biomedical Engineering. 2013 | Pubmed ID: 23642241 P21 Activated Kinase Signaling Coordinates Glycoprotein Receptor VI-mediated Platelet Aggregation, Lamellipodia Formation, and Aggregate Stability Under Shear Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2013 | Pubmed ID: 23640496 A Physical Sciences Network Characterization of Non-tumorigenic and Metastatic Cells Scientific Reports. 2013 | Pubmed ID: 23618955 Physiological Levels of Blood Coagulation Factors IX and X Control Coagulation Kinetics in an in Vitro Model of Circulating Tissue Factor Physical Biology. Jun, 2013 | Pubmed ID: 23585459 Quantification of Volume, Mass, and Density of Thrombus Formation Using Brightfield and Differential Interference Contrast Microscopy Journal of Biomedical Optics. Jan, 2013 | Pubmed ID: 23348747 Hyaluronan Oligosaccharides Perturb Lymphocyte Slow Rolling on Brain Vascular Endothelial Cells: Implications for Inflammatory Demyelinating Disease Matrix Biology : Journal of the International Society for Matrix Biology. Apr, 2013 | Pubmed ID: 23333375 Gammaherpesvirus Latency Induces Antibody-associated Thrombocytopenia in Mice Journal of Autoimmunity. May, 2013 | Pubmed ID: 23245703 Molecular Imaging of Inflammation and Platelet Adhesion in Advanced Atherosclerosis Effects of Antioxidant Therapy with NADPH Oxidase Inhibition Circulation. Cardiovascular Imaging. Jan, 2013 | Pubmed ID: 23239832 Exogenous Modification of Platelet Membranes with the Omega-3 Fatty Acids EPA and DHA Reduces Platelet Procoagulant Activity and Thrombus Formation American Journal of Physiology. Cell Physiology. Feb, 2013 | Pubmed ID: 23174566 Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice Translational Stroke Research. Sep, 2012 | Pubmed ID: 23634198 Development of a Label-free Imaging Technique for the Quantification of Thrombus Formation Cellular and Molecular Bioengineering. Dec, 2012 | Pubmed ID: 23585817 Modeling and Simulation of Procoagulant Circulating Tumor Cells in Flow Frontiers in Oncology. 2012 | Pubmed ID: 23050240 Measurement of Single Cell Refractive Index, Dry Mass, Volume, and Density Using a Transillumination Microscope Physical Review Letters. Sep, 2012 | Pubmed ID: 23005682 Do Circulating Tumor Cells Play a Role in Coagulation and Thrombosis? Frontiers in Oncology. 2012 | Pubmed ID: 22973557 Development of Coagulation Factor Probes for the Identification of Procoagulant Circulating Tumor Cells Frontiers in Oncology. 2012 | Pubmed ID: 22973554 Quantification of Cellular Volume and Sub-cellular Density Fluctuations: Comparison of Normal Peripheral Blood Cells and Circulating Tumor Cells Identified in a Breast Cancer Patient Frontiers in Oncology. 2012 | Pubmed ID: 22934287 Hyaluronan Anchored to Activated CD44 on Central Nervous System Vascular Endothelial Cells Promotes Lymphocyte Extravasation in Experimental Autoimmune Encephalomyelitis The Journal of Biological Chemistry. Sep, 2012 | Pubmed ID: 22865853 Optical Quantification of Cellular Mass, Volume, and Density of Circulating Tumor Cells Identified in an Ovarian Cancer Patient Frontiers in Oncology. 2012 | Pubmed ID: 22826822 Regulation of the MTOR-Rac1 Axis in Platelet Function Small GTPases. Jan-Mar, 2012 | Pubmed ID: 22714420 Inhibition of Factor XI Activation Attenuates Inflammation and Coagulopathy While Improving the Survival of Mouse Polymicrobial Sepsis Blood. May, 2012 | Pubmed ID: 22442348 Optical Detection of Indocyanine Green Encapsulated Biocompatible Poly (lactic-co-glycolic) Acid Nanoparticles with Photothermal Optical Coherence Tomography Optics Letters. Mar, 2012 | Pubmed ID: 22378459 Platelet Shape Change and Spreading Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22130702 Activated Factor XI Inhibits Chemotaxis of Polymorphonuclear Leukocytes Journal of Leukocyte Biology. Nov, 2011 | Pubmed ID: 21807745 S6K1 and MTOR Regulate Rac1-driven Platelet Activation and Aggregation Blood. Sep, 2011 | Pubmed ID: 21757621 Thrombin Mutant W215A/E217A Treatment Improves Neurological Outcome and Reduces Cerebral Infarct Size in a Mouse Model of Ischemic Stroke Stroke; a Journal of Cerebral Circulation. Jun, 2011 | Pubmed ID: 21512172 Breakup Feared After Filamin Leaves GPIb Blood. Mar, 2011 | Pubmed ID: 21372161 Molecular Imaging of Activated Von Willebrand Factor to Detect High-risk Atherosclerotic Phenotype JACC. Cardiovascular Imaging. Sep, 2010 | Pubmed ID: 20846630 A Role for Factor XIIa-mediated Factor XI Activation in Thrombus Formation in Vivo Blood. Nov, 2010 | Pubmed ID: 20634381 Safety and Antithrombotic Efficacy of Moderate Platelet Count Reduction by Thrombopoietin Inhibition in Primates Science Translational Medicine. Jun, 2010 | Pubmed ID: 20574069 Binding of Recombinant T Cell Receptor Ligands (RTL) to Antigen Presenting Cells Prevents Upregulation of CD11b and Inhibits T Cell Activation and Transfer of Experimental Autoimmune Encephalomyelitis Journal of Neuroimmunology. Aug, 2010 | Pubmed ID: 20546940 Spatial Distribution of Factor Xa, Thrombin, and Fibrin(ogen) on Thrombi at Venous Shear PloS One. 2010 | Pubmed ID: 20454680 Cytoskeletal Structure Regulates Endothelial Cell Immunogenicity Independent of Fluid Shear Stress American Journal of Physiology. Cell Physiology. Feb, 2010 | Pubmed ID: 19923423 Effect of Sex Difference on Platelet Adhesion, Spreading and Aggregate Formation Under Flow Thrombosis and Haemostasis. Nov, 2009 | Pubmed ID: 19888535 Identification of Coagulation Factor XI As a Ligand for Platelet Apolipoprotein E Receptor 2 (ApoER2) Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2009 | Pubmed ID: 19661487 Single Particle Quantum Dot Imaging Achieves Ultrasensitive Detection Capabilities for Western Immunoblot Analysis ACS Nano. Jun, 2009 | Pubmed ID: 19453141 Small-molecule Inhibitors of Integrin Alpha2beta1 That Prevent Pathological Thrombus Formation Via an Allosteric Mechanism Proceedings of the National Academy of Sciences of the United States of America. Jan, 2009 | Pubmed ID: 19141632 Activated Protein C Ligation of ApoER2 (LRP8) Causes Dab1-dependent Signaling in U937 Cells Proceedings of the National Academy of Sciences of the United States of America. Jan, 2009 | Pubmed ID: 19116273 Distinct Extracellular Matrix Microenvironments of Progenitor and Carotid Endothelial Cells Journal of Biomedical Materials Research. Part A. Nov, 2009 | Pubmed ID: 18985765 Prevention of Vascular Graft Occlusion and Thrombus-associated Thrombin Generation by Inhibition of Factor XI Blood. Jan, 2009 | Pubmed ID: 18945968 Capture of Flowing Endothelial Cells Using Surface-immobilized Anti-kinase Insert Domain Receptor Antibody Tissue Engineering. Part C, Methods. Jun, 2008 | Pubmed ID: 18544026 Thrombin Mutant W215A/E217A Acts As a Platelet GPIb Antagonist Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2008 | Pubmed ID: 17962622 La Saratina Producto Leech Es Un Potente Inhibidor De La Integrina Plaquetaria Alpha2beta1 Y Von Willebrand Factor De Unión De Colágeno The FEBS Journal. Mar, 2007 | Pubmed ID: 17489103 Minimal Regulation of Platelet Activity by PECAM-1 Platelets. Feb, 2007 | Pubmed ID: 17365855 Relative Antithrombotic and Antihemostatic Effects of Protein C Activator Versus Low-molecular-weight Heparin in Primates Blood. May, 2007 | Pubmed ID: 17227834 GPVI Potentiation of Platelet Activation by Thrombin and Adhesion Molecules Independent of Src Kinases and Syk Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2007 | Pubmed ID: 17110603 Vav Family Proteins Are Required for Optimal Regulation of PLCgamma2 by Integrin AlphaIIbbeta3 The Biochemical Journal. Feb, 2007 | Pubmed ID: 17054426 Distinct but Critical Roles for Integrin AlphaIIbbeta3 in Platelet Lamellipodia Formation on Fibrinogen, Collagen-related Peptide and Thrombin The FEBS Journal. Nov, 2006 | Pubmed ID: 17032352 Laminin Stimulates Spreading of Platelets Through Integrin Alpha6beta1-dependent Activation of GPVI Blood. Feb, 2006 | Pubmed ID: 16219796 Rac1 is Essential for Platelet Lamellipodia Formation and Aggregate Stability Under Flow The Journal of Biological Chemistry. Nov, 2005 | Pubmed ID: 16195235 Preferential Binding of Platelets to Monocytes over Neutrophils Under Flow Biochemical and Biophysical Research Communications. Apr, 2005 | Pubmed ID: 15721313 Evaluation of Platelet Antagonists in in Vitro Flow Models of Thrombosis Methods in Molecular Medicine. 2004 | Pubmed ID: 14733325 Exogenous Eosinophil Activation Converts PSGL-1-dependent Binding to CD18-dependent Stable Adhesion to Platelets in Shear Flow American Journal of Physiology. Cell Physiology. May, 2003 | Pubmed ID: 12529243 Fluid Shear Regulates the Kinetics and Molecular Mechanisms of Activation-dependent Platelet Binding to Colon Carcinoma Cells Biophysical Journal. Aug, 2002 | Pubmed ID: 12124268 Comparative Efficacy Between the Glycoprotein IIb/IIIa Antagonists Roxifiban and Orbofiban in Inhibiting Platelet Responses in Flow Models of Thrombosis Journal of Cardiovascular Pharmacology. Apr, 2002 | Pubmed ID: 11904529 Microscopía óptica cuantitativa: Medición de Biofísica Celular Características con un microscopio óptico estándar Kevin G. Phillips1,2, Sandra M. Baker-Groberg1, Owen J.T. McCarty1,3 1Department of Biomedical Engineering, Oregon Health & Science University, School of Medicine, 2Department of Dermatology, Oregon Health & Science University, School of Medicine, 3Department of Cell & Developmental Biology, Division of Hematology & Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, School of Medicine Bioingegneria
Microscopía óptica cuantitativa: Medición de Biofísica Celular Características con un microscopio óptico estándar Kevin G. Phillips1,2, Sandra M. Baker-Groberg1, Owen J.T. McCarty1,3 1Department of Biomedical Engineering, Oregon Health & Science University, School of Medicine, 2Department of Dermatology, Oregon Health & Science University, School of Medicine, 3Department of Cell & Developmental Biology, Division of Hematology & Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, School of Medicine Bioingegneria