Paola Melotti Centro Fibrosi Cistica Azienda Ospedaliera Universitaria Integrata Biography Publications Institution JoVE Articles Paola Melotti has not added a biography. If you are Paola Melotti and would like to personalize this page please email our Author Liaison for assistance. Publications When and How Ruling out Cystic Fibrosis in Adult Patients with Bronchiectasis Multidisciplinary Respiratory Medicine. 2018 | Pubmed ID: 30151190 Inhibition of Pseudomonas Aeruginosa Secreted Virulence Factors Reduces Lung Inflammation in CF Mice Virulence. 2018 | Pubmed ID: 29938577 Ratiometric Sweat Secretion Optical Test in Cystic Fibrosis, Carriers and Healthy Subjects Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. Mar, 2018 | Pubmed ID: 29292091 Azithromycin Attenuates Pseudomonas-Induced Lung Inflammation by Targeting Bacterial Proteins Secreted in the Cultured Medium Frontiers in Immunology. 2016 | Pubmed ID: 27895643 Whole-gene CFTR Sequencing Combined with Digital RT-PCR Improves Genetic Diagnosis of Cystic Fibrosis Journal of Human Genetics. Dec, 2016 | Pubmed ID: 27488443 In Vivo Monitoring of Lung Inflammation in CFTR-deficient Mice Journal of Translational Medicine. Jul, 2016 | Pubmed ID: 27468800 Nasal Potential Difference Outcomes Support Diagnostic Decisions in Cystic Fibrosis Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. Sep, 2016 | Pubmed ID: 27423539 Genotypic and Phenotypic Relatedness of Pseudomonas Aeruginosa Isolates Among the Major Cystic Fibrosis Patient Cohort in Italy BMC Microbiology. Jul, 2016 | Pubmed ID: 27400750 Biogenic Selenium Nanoparticles: Characterization, Antimicrobial Activity and Effects on Human Dendritic Cells and Fibroblasts Microbial Biotechnology. Nov, 2016 | Pubmed ID: 27319803 HLA-G Expression and Regulation During Pseudomonas Aeruginosa Infection in Cystic Fibrosis Patients Future Microbiology. 2016 | Pubmed ID: 26934639 Mutations of Cystic Fibrosis Transmembrane Conductance Regulator Gene Cause a Monocyte-Selective Adhesion Deficiency American Journal of Respiratory and Critical Care Medicine. May, 2016 | Pubmed ID: 26694899 In Vivo Imaging of the Lung Inflammatory Response to Pseudomonas Aeruginosa and Its Modulation by Azithromycin Journal of Translational Medicine. Aug, 2015 | Pubmed ID: 26239109 Impact of MIF Gene Promoter Polymorphism on F508del Cystic Fibrosis Patients PloS One. 2014 | Pubmed ID: 25503271 Electrophysiological Evaluation of Cystic Fibrosis Conductance Transmembrane Regulator (CFTR) Expression in Human Monocytes Biochimica Et Biophysica Acta. Oct, 2014 | Pubmed ID: 25046381 Ataluren for the Treatment of Nonsense-mutation Cystic Fibrosis: a Randomised, Double-blind, Placebo-controlled Phase 3 Trial The Lancet. Respiratory Medicine. Jul, 2014 | Pubmed ID: 24836205 Detection of CFTR Protein in Human Leukocytes by Flow Cytometry Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Jul, 2014 | Pubmed ID: 24623386 Challenging the Diagnosis of Cystic Fibrosis in a Patient Carrying the 186-8T/C Allelic Variant in the CF Transmembrane Conductance Regulator Gene BMC Pulmonary Medicine. Mar, 2014 | Pubmed ID: 24621136 Glutathione Inhalation Treatments in Cystic Fibrosis: the Interference of Airway γ-glutamyltransferase American Journal of Respiratory and Critical Care Medicine. Jan, 2014 | Pubmed ID: 24428657 Nasal Potential Difference Measurements in Diagnosis of Cystic Fibrosis: an International Survey Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. Jan, 2014 | Pubmed ID: 24022019 γ-Glutamyltransferase Catabolism of S-nitrosoglutathione Modulates IL-8 Expression in Cystic Fibrosis Bronchial Epithelial Cells Free Radical Biology & Medicine. Dec, 2013 | Pubmed ID: 23820266 Impaired CFTR Function in Mild Cystic Fibrosis Associated with the S977F/T5TG12complex Allele in Trans with F508del Mutation Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. Dec, 2013 | Pubmed ID: 23361109 Influence of Perfusate Temperature on Nasal Potential Difference The European Respiratory Journal. Aug, 2013 | Pubmed ID: 23100510 Contribution by Polymorphonucleate Granulocytes to Elevated Gamma-glutamyltransferase in Cystic Fibrosis Sputum PloS One. 2012 | Pubmed ID: 22496859 MudPIT Analysis of Released Proteins in Pseudomonas Aeruginosa Laboratory and Clinical Strains in Relation to Pro-inflammatory Effects Integrative Biology : Quantitative Biosciences from Nano to Macro. Mar, 2012 | Pubmed ID: 22298109 Defective CFTR Expression and Function Are Detectable in Blood Monocytes: Development of a New Blood Test for Cystic Fibrosis PloS One. 2011 | Pubmed ID: 21811577 Impact of Polymorphism of Multidrug Resistance-associated Protein 1 (ABCC1) Gene on the Severity of Cystic Fibrosis Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. Jul, 2011 | Pubmed ID: 21435954 An Interactive Computer Program Can Effectively Educate Potential Users of Cystic Fibrosis Carrier Tests American Journal of Medical Genetics. Part A. Apr, 2011 | Pubmed ID: 21416590 Whole Blood Fatty Acid Analysis with Micromethod in Cystic Fibrosis and Pulmonary Disease Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. May, 2010 | Pubmed ID: 20338832 Editorial: The Role of Macrophages and Their Scavenger Receptors in Cystic Fibrosis Journal of Leukocyte Biology. Sep, 2009 | Pubmed ID: 19720614 CFTR Mutation in an Arab Patient: Clinical and Functional Features of 875+1G-->A/875+1G-->A Genotype Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. Jul, 2009 | Pubmed ID: 19481507 Effects of Azithromycin on Glutathione S-transferases in Cystic Fibrosis Airway Cells American Journal of Respiratory Cell and Molecular Biology. Aug, 2009 | Pubmed ID: 19097986 Protein Tyrosine Phosphatase Gamma (PTPgamma) is a Novel Leukocyte Marker Highly Expressed by CD34 Precursors Biomarker Insights. May, 2007 | Pubmed ID: 19662205 TG15 T5 Allele in Clinically Discordant Monozygotic Twins with Cystic Fibrosis American Journal of Medical Genetics. Part A. Aug, 2007 | Pubmed ID: 17632788 Azithromycin Selectively Reduces Tumor Necrosis Factor Alpha Levels in Cystic Fibrosis Airway Epithelial Cells Antimicrobial Agents and Chemotherapy. Mar, 2007 | Pubmed ID: 17210769 Anti-inflammatory Effects of Azithromycin in Cystic Fibrosis Airway Epithelial Cells Biochemical and Biophysical Research Communications. Dec, 2006 | Pubmed ID: 17045242 Interaction of Adenovirus Type 5 Fiber with the Coxsackievirus and Adenovirus Receptor Activates Inflammatory Response in Human Respiratory Cells Journal of Virology. Nov, 2006 | Pubmed ID: 16956941 The GCC Repeat Length in the 5'UTR of MRP1 Gene is Polymorphic: a Functional Characterization of Its Relevance for Cystic Fibrosis BMC Medical Genetics. Feb, 2006 | Pubmed ID: 16464259 MAP Kinases and NF-kappaB Collaborate to Induce ICAM-1 Gene Expression in the Early Phase of Adenovirus Infection Virology. Mar, 2003 | Pubmed ID: 12667793 Standardized Measurement of Nasal Membrane Transepithelial Potential Difference (NPD) George M. Solomon1, Inez Bronsveld2, Kathryn Hayes3, Michael Wilschanski4, Paola Melotti5, Steven M. Rowe1, Isabelle Sermet-Gaudelus6,7 1Department of Medicine and the Gregory Fleming James Cystic Fibrosis Center, University of Alabama at Birmingham, 2Department of Pulmonology and Tuberculosis, University Medical Center Utrecht, 3Center for Experimental Medicine, Queens University, Northern Ireland, 4Hadassah Hebrew University Medical Center, Jerusalem, 5Centro Fibrosi Cistica, Azienda Ospedaliera Universitaria Integrata, 6Service de Pneumologie et Allergologie Pédiatriques and Center de Ressources et de Compétence de la Mucoviscidose, Hôpital Necker Enfants Malades, 7INSERM U 1151, Institut Necker Enfants Malades JoVE 57006 Medicina An IL-8 Transiently Transgenized Mouse Model for the In Vivo Long-term Monitoring of Inflammatory Responses Gabriella Bergamini*1, Fabio Stellari*2, Angela Sandri*3, Maria M. Lleo3, Gaetano Donofrio4, Francesca Ruscitti5,2, Federico Boschi6, Andrea Sbarbati7, Gino Villetti2, Paola Melotti8, Claudio Sorio1 1Department of Medicine, General Pathology Division, Cystic Fibrosis Translational Research Laboratory "D. Lissandrini", University of Verona, 2Corporate Preclinical R&D, Chiesi Farmaceutici S.p.A., 3Department of Diagnostic and Public Health, Microbiology Division, University of Verona, 4Dipartimento di Scienze Medico-Veterinarie, University of Parma, 5Department of Biomedical Biotechnological and Translational Sciences, University of Parma, 6Department of Computer Science, University of Verona, 7Department of Neurological, Biomedical and Movement Sciences, University of Verona, 8Cystic Fibrosis Regional Center (CFC), AOUI Verona JoVE 55499 Immunologia e infezioni
Standardized Measurement of Nasal Membrane Transepithelial Potential Difference (NPD) George M. Solomon1, Inez Bronsveld2, Kathryn Hayes3, Michael Wilschanski4, Paola Melotti5, Steven M. Rowe1, Isabelle Sermet-Gaudelus6,7 1Department of Medicine and the Gregory Fleming James Cystic Fibrosis Center, University of Alabama at Birmingham, 2Department of Pulmonology and Tuberculosis, University Medical Center Utrecht, 3Center for Experimental Medicine, Queens University, Northern Ireland, 4Hadassah Hebrew University Medical Center, Jerusalem, 5Centro Fibrosi Cistica, Azienda Ospedaliera Universitaria Integrata, 6Service de Pneumologie et Allergologie Pédiatriques and Center de Ressources et de Compétence de la Mucoviscidose, Hôpital Necker Enfants Malades, 7INSERM U 1151, Institut Necker Enfants Malades JoVE 57006 Medicina
An IL-8 Transiently Transgenized Mouse Model for the In Vivo Long-term Monitoring of Inflammatory Responses Gabriella Bergamini*1, Fabio Stellari*2, Angela Sandri*3, Maria M. Lleo3, Gaetano Donofrio4, Francesca Ruscitti5,2, Federico Boschi6, Andrea Sbarbati7, Gino Villetti2, Paola Melotti8, Claudio Sorio1 1Department of Medicine, General Pathology Division, Cystic Fibrosis Translational Research Laboratory "D. Lissandrini", University of Verona, 2Corporate Preclinical R&D, Chiesi Farmaceutici S.p.A., 3Department of Diagnostic and Public Health, Microbiology Division, University of Verona, 4Dipartimento di Scienze Medico-Veterinarie, University of Parma, 5Department of Biomedical Biotechnological and Translational Sciences, University of Parma, 6Department of Computer Science, University of Verona, 7Department of Neurological, Biomedical and Movement Sciences, University of Verona, 8Cystic Fibrosis Regional Center (CFC), AOUI Verona JoVE 55499 Immunologia e infezioni