Paul W. M. Fedak Section of Cardiac Surgery, Department of Cardiac Sciences, Libin Cardiovascular Institute Cumming School of Medicine Biography Publications Institution JoVE Articles Paul W. M. Fedak has not added a biography. If you are Paul W. M. Fedak and would like to personalize this page please email our Author Liaison for assistance. Publications Potential Role of Epicardial Adipose Tissue in Coronary Artery Endothelial Cell Dysfunction in Type 2 Diabetes FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2021 | Pubmed ID: 34469050 Post-Operative Adhesions: A Comprehensive Review of Mechanisms Biomedicines. Jul, 2021 | Pubmed ID: 34440071 Prevention of Post-Operative Adhesions: A Comprehensive Review of Present and Emerging Strategies Biomolecules. 07, 2021 | Pubmed ID: 34356652 Aorta-specific DNA Methylation Patterns in Cell-free DNA from Patients with Bicuspid Aortic Valve-associated Aortopathy Clinical Epigenetics. Jul, 2021 | Pubmed ID: 34321094 International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes The Journal of Thoracic and Cardiovascular Surgery. Sep, 2021 | Pubmed ID: 34304896 Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional, and Research Purposes The Journal of Thoracic and Cardiovascular Surgery. 09, 2021 | Pubmed ID: 34304894 Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes The Annals of Thoracic Surgery. Sep, 2021 | Pubmed ID: 34304861 International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes The Annals of Thoracic Surgery. Sep, 2021 | Pubmed ID: 34304860 International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Jul, 2021 | Pubmed ID: 34293102 Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Jul, 2021 | Pubmed ID: 34292332 Commentary: The 4AT Score-Reducing Confusion About Delirium Diagnosis After Cardiac Surgery The Journal of Thoracic and Cardiovascular Surgery. Jun, 2021 | Pubmed ID: 34217535 Commentary: How to Save and Improve the Lives of Families with Heritable Aortic Diseases The Journal of Thoracic and Cardiovascular Surgery. Mar, 2021 | Pubmed ID: 33781592 Mechanical and Structural Remodeling of Cardiac Muscle After Aerobic and Resistance Exercise Training in Rats Medicine and Science in Sports and Exercise. 08, 2021 | Pubmed ID: 33731663 Commentary: Past is Prologue - Leveraging Big Data to Optimize Future Operative Risk Prediction Seminars in Thoracic and Cardiovascular Surgery. Mar, 2021 | Pubmed ID: 33662550 Commentary: A Picture is Worth a Thousand Words: Improving Surgical Approaches Using Advanced Multimodal Cardiac Imaging The Journal of Thoracic and Cardiovascular Surgery. Feb, 2021 | Pubmed ID: 33642107 Commentary: The Promise of Precision Cardiovascular Surgery The Journal of Thoracic and Cardiovascular Surgery. 02, 2021 | Pubmed ID: 31818427 Commentary: Fluoroquinolone Antibiotics Are Antiaortic The Journal of Thoracic and Cardiovascular Surgery. Nov, 2020 | Pubmed ID: 33293062 Commentary: Transplanting the Powerhouse of the Cell to Enhance Cardiopulmonary Repair The Journal of Thoracic and Cardiovascular Surgery. Sep, 2020 | Pubmed ID: 32980149 Commentary: The Mutation Matters: Improving Precision for Surgical Management of Hereditary Aortic Syndromes The Journal of Thoracic and Cardiovascular Surgery. Aug, 2020 | Pubmed ID: 32951878 Commentary: The Return on Investment for Cardiothoracic Surgeon-scientists The Journal of Thoracic and Cardiovascular Surgery. Jul, 2020 | Pubmed ID: 32859412 Surgical Management of the Aorta in BAV Patients Progress in Cardiovascular Diseases. Jul - Aug, 2020 | Pubmed ID: 32640281 The Science of BAV Aortopathy Progress in Cardiovascular Diseases. Jul - Aug, 2020 | Pubmed ID: 32599028 Acellular Bioscaffolds Redirect Cardiac Fibroblasts and Promote Functional Tissue Repair in Rodents and Humans with Myocardial Injury Scientific Reports. 06, 2020 | Pubmed ID: 32528051 Fluoroquinolone-Associated Type A Aortic Dissection in Alpha-1 Anti-Trypsin Deficiency The Annals of Thoracic Surgery. 12, 2020 | Pubmed ID: 32492444 Applications of a Specialty Bicuspid Aortic Valve Program: Clinical Continuity and Translational Collaboration Journal of Clinical Medicine. May, 2020 | Pubmed ID: 32380775 Promoting Cardiac Regeneration and Repair Using Acellular Biomaterials Frontiers in Bioengineering and Biotechnology. 2020 | Pubmed ID: 32363184 Direct Effects of Empagliflozin on Extracellular Matrix Remodelling in Human Cardiac Myofibroblasts: Novel Translational Clues to Explain EMPA-REG OUTCOME Results The Canadian Journal of Cardiology. 04, 2020 | Pubmed ID: 31837891 SKA-31, an Activator of Ca-activated K Channels, Improves Cardiovascular Function in Aging Pharmacological Research. 01, 2020 | Pubmed ID: 31707036 Commentary: Cause or Consequence? The Influence of Mitral Regurgitation on Post-myocardial Infarction Structural Remodeling is Better Defined Using a New Rodent Model The Journal of Thoracic and Cardiovascular Surgery. Sep, 2019 | Pubmed ID: 31610958 Application of Bioengineered Materials in the Surgical Management of Heart Failure Frontiers in Cardiovascular Medicine. 2019 | Pubmed ID: 31482096 On the 'cusp' of Clinical Feasibility: Aortic Wall Shear Stress Derived Non-invasively with 4D Flow MRI Journal of Thoracic Disease. Jul, 2019 | Pubmed ID: 31463155 Gata6 Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis Immunity. 07, 2019 | Pubmed ID: 31315031 Acellular Extracellular Matrix Bioscaffolds for Cardiac Repair and Regeneration Frontiers in Cell and Developmental Biology. 2019 | Pubmed ID: 31080800 Minimally Invasive Cardiac Surgery Presents Challenges for Design of Randomized Clinical Trials The Journal of Thoracic and Cardiovascular Surgery. 04, 2019 | Pubmed ID: 30901801 Evolving Surgical Approaches to Bicuspid Aortic Valve Associated Aortopathy Frontiers in Cardiovascular Medicine. 2019 | Pubmed ID: 30886849 Minimally Invasive Cardiac Surgery and the Importance of Qualitative Patient-centered Metrics to Guide Innovations The Journal of Thoracic and Cardiovascular Surgery. 06, 2019 | Pubmed ID: 30871840 Commentary: Using Ex vivo Modeling to Validate Technical Innovations in Cardiac Surgery The Journal of Thoracic and Cardiovascular Surgery. 08, 2019 | Pubmed ID: 30857816 Utilizing Wall Shear Stress As a Clinical Biomarker for Bicuspid Valve-associated Aortopathy Current Opinion in Cardiology. 03, 2019 | Pubmed ID: 30633073 Induction of Human Aortic Myofibroblast-mediated Extracellular Matrix Dysregulation: A Potential Mechanism of Fluoroquinolone-associated Aortopathy The Journal of Thoracic and Cardiovascular Surgery. 01, 2019 | Pubmed ID: 30528439 Commentary: Structural Valve Degeneration in the Era of Precision Medicine The Journal of Thoracic and Cardiovascular Surgery. 04, 2019 | Pubmed ID: 30389129 Precision and Targeted Therapy in Cardiac Surgery Journal of Thoracic Disease. Nov, 2018 | Pubmed ID: 30631535 Targeting Selected Extracellular Matrix Components to Attenuate Cardiac Fibrosis Annals of Translational Medicine. Nov, 2018 | Pubmed ID: 30613624 Validating Innovations to Improve Recovery After Heart Surgery Annals of Translational Medicine. Nov, 2018 | Pubmed ID: 30613588 Coronary Bypass Surgery for Diabetes and Multivessel Disease: Forget the SYNTAX Journal of the American College of Cardiology. 12, 2018 | Pubmed ID: 30522647 Make Sternotomy Great Again The Journal of Thoracic and Cardiovascular Surgery. 12, 2018 | Pubmed ID: 30107920 Modify, Simplify, Apply: Do We Need Preclinical Models for Surgical Innovation? The Journal of Thoracic and Cardiovascular Surgery. 11, 2018 | Pubmed ID: 30098807 Aortic Valve-mediated Wall Shear Stress is Heterogeneous and Predicts Regional Aortic Elastic Fiber Thinning in Bicuspid Aortic Valve-associated Aortopathy The Journal of Thoracic and Cardiovascular Surgery. 12, 2018 | Pubmed ID: 30060930 The American Association for Thoracic Surgery Consensus Guidelines on Bicuspid Aortic Valve-related Aortopathy: Full Online-only Version The Journal of Thoracic and Cardiovascular Surgery. 08, 2018 | Pubmed ID: 30011777 The American Association for Thoracic Surgery Consensus Guidelines on Bicuspid Aortic Valve-related Aortopathy: Executive Summary The Journal of Thoracic and Cardiovascular Surgery. 08, 2018 | Pubmed ID: 30011756 Human Pericardial Proteoglycan 4 (lubricin): Implications for Postcardiotomy Intrathoracic Adhesion Formation The Journal of Thoracic and Cardiovascular Surgery. 10, 2018 | Pubmed ID: 29859675 Using Acellular Bioactive Extracellular Matrix Scaffolds to Enhance Endogenous Cardiac Repair Frontiers in Cardiovascular Medicine. 2018 | Pubmed ID: 29696148 Aortic Valve Replacement in an Era of Rapid Innovation: Better the Devil You Know Journal of the American College of Cardiology. 04, 2018 | Pubmed ID: 29598860 Aortic Diameter: The Beginning of the End of an Era The Journal of Thoracic and Cardiovascular Surgery. 08, 2018 | Pubmed ID: 29510930 Bridging to Heart Transplant with Extracorporeal Membrane Oxygenation: Good or VAD? The Journal of Thoracic and Cardiovascular Surgery. 04, 2018 | Pubmed ID: 29310932 Seeing a Tree Through the Forest: Precision Medicine Tools Can Enhance Donor Allocation in Heart Transplantation The Journal of Thoracic and Cardiovascular Surgery. 04, 2018 | Pubmed ID: 29310930 Perioperative Evaluation of Regional Aortic Wall Shear Stress Patterns in Patients Undergoing Aortic Valve And/or Proximal Thoracic Aortic Replacement The Journal of Thoracic and Cardiovascular Surgery. 06, 2018 | Pubmed ID: 29248286 Bicuspid Aortic Valve-associated Aortopathy: Update on Biomarkers Current Opinion in Cardiology. 03, 2018 | Pubmed ID: 29095713 Heparin Augmentation Enhances Bioactive Properties of Acellular Extracellular Matrix Scaffold Tissue Engineering. Part A. 01, 2018 | Pubmed ID: 28457186 Bioactive Extracellular Matrix Scaffold Promotes Adaptive Cardiac Remodeling and Repair JACC. Basic to Translational Science. Aug, 2017 | Pubmed ID: 30062163 Empagliflozin Prevents Worsening of Cardiac Function in an Experimental Model of Pressure Overload-Induced Heart Failure JACC. Basic to Translational Science. Aug, 2017 | Pubmed ID: 30062155 Mind the Gap: Current Challenges and Future State of Heart Failure Care The Canadian Journal of Cardiology. 11, 2017 | Pubmed ID: 29111107 Evolution of Precision Medicine and Surgical Strategies for Bicuspid Aortic Valve-Associated Aortopathy Frontiers in Physiology. 2017 | Pubmed ID: 28740468 The Cost of Frailty in Cardiac Surgery The Canadian Journal of Cardiology. 08, 2017 | Pubmed ID: 28666616 Adhesive-Enhanced Sternal Closure: Feasibility and Safety of Late Sternal Reentry Case Reports in Surgery. 2017 | Pubmed ID: 28634566 Bicuspid Aortic Valve Aortopathy: Mechanistic and Clinical Insights from Recent Studies Current Opinion in Cardiology. Mar, 2017 | Pubmed ID: 28182589 Reply: Final Common Pathway of Aortic Dilation?: Heterogeneity of Aortic Wall Property Causes The Aneurysmal Change Journal of the American College of Cardiology. Feb, 2016 | Pubmed ID: 26868701 Un modelo de roedor isquémico de pericardio intacto Ali Fatehi Hassanabad1, Darrell D. Belke1, Jeannine Turnbull1, Jameson A. Dundas1, Vishnu Vasanthan1, Guoqi Teng1, Paul W. M. Fedak1, Justin F. Deniset1,2 1Section of Cardiac Surgery, Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, 2Department of Pharmacology and Physiology, University of Calgary JoVE 62720 Medicina
Un modelo de roedor isquémico de pericardio intacto Ali Fatehi Hassanabad1, Darrell D. Belke1, Jeannine Turnbull1, Jameson A. Dundas1, Vishnu Vasanthan1, Guoqi Teng1, Paul W. M. Fedak1, Justin F. Deniset1,2 1Section of Cardiac Surgery, Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, 2Department of Pharmacology and Physiology, University of Calgary JoVE 62720 Medicina