Paul Timpson The Beatson Institute for Cancer Research University of Glasgow Biography Publications Institution JoVE Articles Paul Timpson has not added a biography. If you are Paul Timpson and would like to personalize this page please email our Author Liaison for assistance. Publications Rab25 and CLIC3 Collaborate to Promote Integrin Recycling from Late Endosomes/Lysosomes and Drive Cancer Progression Developmental Cell. Jan, 2012 | Pubmed ID: 22197222 FLIM-FRET Imaging in Vivo Reveals 3D-environment Spatially Regulates RhoGTPase Activity During Cancer Cell Invasion Small GTPases. 7, 2011 | Pubmed ID: 22145098 P-Rex1 is Required for Efficient Melanoblast Migration and Melanoma Metastasis Nature Communications. 2011 | Pubmed ID: 22109529 Imaging Molecular Dynamics in Vivo--from Cell Biology to Animal Models Journal of Cell Science. Sep, 2011 | Pubmed ID: 21878495 Actomyosin-mediated Cellular Tension Drives Increased Tissue Stiffness and β-catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth Cancer Cell. Jun, 2011 | Pubmed ID: 21665151 Spatial Regulation of RhoA Activity During Pancreatic Cancer Cell Invasion Driven by Mutant P53 Cancer Research. Feb, 2011 | Pubmed ID: 21266354 Quantitative in Vivo Imaging of the Effects of Inhibiting Integrin Signaling Via Src and FAK on Cancer Cell Movement: Effects on E-cadherin Dynamics Cancer Research. Nov, 2010 | Pubmed ID: 21045155 Dasatinib Inhibits the Development of Metastases in a Mouse Model of Pancreatic Ductal Adenocarcinoma Gastroenterology. Jul, 2010 | Pubmed ID: 20303350 Mutant P53 Drives Metastasis and Overcomes Growth Arrest/senescence in Pancreatic Cancer Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 20018721 Quantitative Real-time Imaging of Molecular Dynamics During Cancer Cell Invasion and Metastasis in Vivo Cell Adhesion & Migration. Oct-Dec, 2009 | Pubmed ID: 19690469 Real-time Study of E-cadherin and Membrane Dynamics in Living Animals: Implications for Disease Modeling and Drug Development Cancer Research. Apr, 2009 | Pubmed ID: 19318551 Phosphorylation-dependent Binding of 14-3-3 Terminates Signalling by the Gab2 Docking Protein The EMBO Journal. Sep, 2008 | Pubmed ID: 19172738 Protein Kinase Cdelta and Calmodulin Regulate Epidermal Growth Factor Receptor Recycling from Early Endosomes Through Arp2/3 Complex and Cortactin Molecular Biology of the Cell. Jan, 2008 | Pubmed ID: 17959830 Aberrant Expression of Cortactin in Head and Neck Squamous Cell Carcinoma Cells is Associated with Enhanced Cell Proliferation and Resistance to the Epidermal Growth Factor Receptor Inhibitor Gefitinib Cancer Research. Oct, 2007 | Pubmed ID: 17909038 Src-dependent Phosphorylation of Scar1 Promotes Its Association with the Arp2/3 Complex Cell Motility and the Cytoskeleton. Jan, 2006 | Pubmed ID: 16317717 Cortactin Overexpression Inhibits Ligand-induced Down-regulation of the Epidermal Growth Factor Receptor Cancer Research. Apr, 2005 | Pubmed ID: 15833860 Distinction at the Leading Edge of the Cell BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Apr, 2005 | Pubmed ID: 15770683 A Role for the Actin Cytoskeleton in Cell Death and Aging in Yeast The Journal of Cell Biology. Mar, 2004 | Pubmed ID: 15024029 Organotypic Collagen I Assay: A Malleable Platform to Assess Cell Behaviour in a 3-Dimensional Context Paul Timpson1, Ewan J. Mcghee1, Zahra Erami1, Max Nobis1, Jean A. Quinn2, Mike Edward2, Kurt I. Anderson1 1The Beatson Institute for Cancer Research, University of Glasgow, 2Section of Dermatology, School of Medicine, University of Glasgow JoVE 3089 Bioingegneria
Organotypic Collagen I Assay: A Malleable Platform to Assess Cell Behaviour in a 3-Dimensional Context Paul Timpson1, Ewan J. Mcghee1, Zahra Erami1, Max Nobis1, Jean A. Quinn2, Mike Edward2, Kurt I. Anderson1 1The Beatson Institute for Cancer Research, University of Glasgow, 2Section of Dermatology, School of Medicine, University of Glasgow JoVE 3089 Bioingegneria