Pepper Schedin Department of Cell, Developmental and Cancer Biology Oregon Health and Science University Biography Publications Institution JoVE Articles Pepper Schedin has not added a biography. If you are Pepper Schedin and would like to personalize this page please email our Author Liaison for assistance. Publications The Rodent Liver Undergoes Weaning-Induced Involution and Supports Breast Cancer Metastasis Cancer Discovery. Dec, 2016 | Pubmed ID: 27974414 Quantitative Extracellular Matrix Proteomics to Study Mammary and Liver Tissue Microenvironments The International Journal of Biochemistry & Cell Biology. Dec, 2016 | Pubmed ID: 27771439 Myoepithelial Cells in Lobular Carcinoma in Situ: Distribution and Immunophenotype Human Pathology. Sep, 2016 | Pubmed ID: 27195907 COX-2 Modulates Mammary Tumor Progression in Response to Collagen Density Breast Cancer Research : BCR. Mar, 2016 | Pubmed ID: 27000374 Breast Cancer Risk Factor Associations Differ for Pure Versus Invasive Carcinoma with an in Situ Component in Case-control and Case-case Analyses Cancer Causes & Control : CCC. Feb, 2016 | Pubmed ID: 26621543 Myoepithelial Cell Differentiation Markers in Ductal Carcinoma in Situ Progression The American Journal of Pathology. Nov, 2015 | Pubmed ID: 26343330 Important Role of Menarche in Development of Estrogen Receptor-Negative Breast Cancer in African American Women Journal of the National Cancer Institute. Sep, 2015 | Pubmed ID: 26085483 Molecular Phenotype of Breast Cancer According to Time Since Last Pregnancy in a Large Cohort of Young Women The Oncologist. Jul, 2015 | Pubmed ID: 26025931 A Case-control Analysis of Oral Contraceptive Use and Breast Cancer Subtypes in the African American Breast Cancer Epidemiology and Risk Consortium Breast Cancer Research : BCR. Feb, 2015 | Pubmed ID: 25849024 Tumor Mechanics and Metabolic Dysfunction Free Radical Biology & Medicine. Feb, 2015 | Pubmed ID: 25532934 Wound Healing-like Immune Program Facilitates Postpartum Mammary Gland Involution and Tumor Progression International Journal of Cancer. Apr, 2015 | Pubmed ID: 25187059 Parity, Lactation, and Breast Cancer Subtypes in African American Women: Results from the AMBER Consortium Journal of the National Cancer Institute. Oct, 2014 | Pubmed ID: 25224496 Cyclooxygenase-2-dependent Lymphangiogenesis Promotes Nodal Metastasis of Postpartum Breast Cancer The Journal of Clinical Investigation. Sep, 2014 | Pubmed ID: 25133426 Mammary Gland Involution As an Immunotherapeutic Target for Postpartum Breast Cancer Journal of Mammary Gland Biology and Neoplasia. Jul, 2014 | Pubmed ID: 24952477 Postpartum Breast Involution Reveals Regression of Secretory Lobules Mediated by Tissue-remodeling Breast Cancer Research : BCR. Mar, 2014 | Pubmed ID: 24678808 Physiological COX-2 Expression in Breast Epithelium Associates with COX-2 Levels in Ductal Carcinoma in Situ and Invasive Breast Cancer in Young Women The American Journal of Pathology. Apr, 2014 | Pubmed ID: 24518566 Mechanism and Preclinical Prevention of Increased Breast Cancer Risk Caused by Pregnancy ELife. Dec, 2013 | Pubmed ID: 24381245 Rab40b Regulates Trafficking of MMP2 and MMP9 During Invadopodia Formation and Invasion of Breast Cancer Cells Journal of Cell Science. Oct, 2013 | Pubmed ID: 23902685 Collagen Architecture in Pregnancy-induced Protection from Breast Cancer Journal of Cell Science. Sep, 2013 | Pubmed ID: 23843613 Developmental Windows of Breast Cancer Risk Provide Opportunities for Targeted Chemoprevention Experimental Cell Research. Jul, 2013 | Pubmed ID: 23664839 Genomic Signatures of Pregnancy-associated Breast Cancer Epithelia and Stroma and Their Regulation by Estrogens and Progesterone Hormones & Cancer. Jun, 2013 | Pubmed ID: 23479404 Postpartum Diagnosis Demonstrates a High Risk for Metastasis and Merits an Expanded Definition of Pregnancy-associated Breast Cancer Breast Cancer Research and Treatment. Apr, 2013 | Pubmed ID: 23430224 Postpartum Remodeling, Lactation, and Breast Cancer Risk: Summary of a National Cancer Institute-sponsored Workshop Journal of the National Cancer Institute. Feb, 2013 | Pubmed ID: 23264680 Hypothesized Role of Pregnancy Hormones on HER2+ Breast Tumor Development Breast Cancer Research and Treatment. Jan, 2013 | Pubmed ID: 23135573 Obesity and Overfeeding Affecting Both Tumor and Systemic Metabolism Activates the Progesterone Receptor to Contribute to Postmenopausal Breast Cancer Cancer Research. Dec, 2012 | Pubmed ID: 23222299 Rat Mammary Extracellular Matrix Composition and Response to Ibuprofen Treatment During Postpartum Involution by Differential GeLC-MS/MS Analysis Journal of Proteome Research. Oct, 2012 | Pubmed ID: 22897585 Alterations in Mast Cell Frequency and Relationship to Angiogenesis in the Rat Mammary Gland During Windows of Physiologic Tissue Remodeling Developmental Dynamics : an Official Publication of the American Association of Anatomists. May, 2012 | Pubmed ID: 22431477 Emerging Targets for the Prevention of Pregnancy-associated Breast Cancer Cell Cycle (Georgetown, Tex.). Feb, 2012 | Pubmed ID: 22374663 Macrophages Are Crucial for Epithelial Cell Death and Adipocyte Repopulation During Mammary Gland Involution Development (Cambridge, England). Jan, 2012 | Pubmed ID: 22129827 Pregnancy-associated Breast Cancer: an Entity Needing Refinement of the Definition Cancer. Jul, 2012 | Pubmed ID: 22086839 Non-steroidal Anti-inflammatory Drugs Target the Pro-tumorigenic Extracellular Matrix of the Postpartum Mammary Gland The International Journal of Developmental Biology. 2011 | Pubmed ID: 22161831 Postpartum Mammary Gland Involution Drives Progression of Ductal Carcinoma in Situ Through Collagen and COX-2 Nature Medicine. Sep, 2011 | Pubmed ID: 21822285 Clusterin Induces Matrix Metalloproteinase-9 Expression Via ERK1/2 and PI3K/Akt/NF-κB Pathways in Monocytes/macrophages Journal of Leukocyte Biology. Oct, 2011 | Pubmed ID: 21742938 Mammary Gland ECM Remodeling, Stiffness, and Mechanosignaling in Normal Development and Tumor Progression Cold Spring Harbor Perspectives in Biology. Jan, 2011 | Pubmed ID: 20980442 Effect of the Estrous Cycle and Surgical Ovariectomy on Energy Balance, Fuel Utilization, and Physical Activity in Lean and Obese Female Rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Dec, 2010 | Pubmed ID: 20926768 Editorial: The Mammary Stroma in Normal Development and Function Journal of Mammary Gland Biology and Neoplasia. Sep, 2010 | Pubmed ID: 20824491 Extracellular Matrix Composition Reveals Complex and Dynamic Stromal-epithelial Interactions in the Mammary Gland Journal of Mammary Gland Biology and Neoplasia. Sep, 2010 | Pubmed ID: 20811805 Isolation of Mammary-specific Extracellular Matrix to Assess Acute Cell-ECM Interactions in 3D Culture Journal of Mammary Gland Biology and Neoplasia. Sep, 2010 | Pubmed ID: 20680416 Benign Mammary Epithelial Cells Enhance the Transformed Phenotype of Human Breast Cancer Cells BMC Cancer. Jul, 2010 | Pubmed ID: 20637104 Alternatively Activated Macrophages and Collagen Remodeling Characterize the Postpartum Involuting Mammary Gland Across Species The American Journal of Pathology. Mar, 2010 | Pubmed ID: 20110414 Quantitative Analysis of Three-dimensional Human Mammary Epithelial Tissue Architecture Reveals a Role for Tenascin-C in Regulating C-met Function The American Journal of Pathology. Feb, 2010 | Pubmed ID: 20042668 A Surprising Link Between the Energetics of Ovariectomy-induced Weight Gain and Mammary Tumor Progression in Obese Rats Obesity (Silver Spring, Md.). Apr, 2010 | Pubmed ID: 19798068 The Complexity of the Relationships Between Age at First Birth and Breast Cancer Incidence Curves Implicate Pregnancy in Cancer Initiation As Well As Promotion of Existing Lesions. Preface Journal of Mammary Gland Biology and Neoplasia. Jun, 2009 | Pubmed ID: 19437108 Pregnancy and Breast Cancer: when They Collide Journal of Mammary Gland Biology and Neoplasia. Jun, 2009 | Pubmed ID: 19381788 An In-solution Ultrasonication-assisted Digestion Method for Improved Extracellular Matrix Proteome Coverage Molecular & Cellular Proteomics : MCP. Jul, 2009 | Pubmed ID: 19351662 Macrophages in Breast Cancer: Do Involution Macrophages Account for the Poor Prognosis of Pregnancy-associated Breast Cancer? Journal of Mammary Gland Biology and Neoplasia. Jun, 2009 | Pubmed ID: 19350209 Breaking Down Barriers: the Importance of the Stromal Microenvironment in Acquiring Invasiveness in Young Women's Breast Cancer Breast Cancer Research : BCR. 2009 | Pubmed ID: 19344495 Identifying Significant Temporal Variation in Time Course Microarray Data Without Replicates BMC Bioinformatics. Mar, 2009 | Pubmed ID: 19323838 Tamoxifen Induces Pleiotrophic Changes in Mammary Stroma Resulting in Extracellular Matrix That Suppresses Transformed Phenotypes Breast Cancer Research : BCR. 2009 | Pubmed ID: 19173736 Loss of Singleminded-2s in the Mouse Mammary Gland Induces an Epithelial-mesenchymal Transition Associated with Up-regulation of Slug and Matrix Metalloprotease 2 Molecular and Cellular Biology. Mar, 2008 | Pubmed ID: 18160708 Whole-food Sources of Vitamin A More Effectively Inhibit Female Rat Sexual Maturation, Mammary Gland Development, and Mammary Carcinogenesis Than Retinyl Palmitate The Journal of Nutrition. Jun, 2007 | Pubmed ID: 17513400 Microenvironment of the Involuting Mammary Gland Mediates Mammary Cancer Progression Journal of Mammary Gland Biology and Neoplasia. Mar, 2007 | Pubmed ID: 17318269 Inhibition of Breast Cancer Growth and Invasion by Single-minded 2s Carcinogenesis. Feb, 2007 | Pubmed ID: 16840439 Pregnancy-associated Breast Cancer and Metastasis Nature Reviews. Cancer. Apr, 2006 | Pubmed ID: 16557280 Remodeling of the Mammary Microenvironment After Lactation Promotes Breast Tumor Cell Metastasis The American Journal of Pathology. Feb, 2006 | Pubmed ID: 16436674 Mammary ECM Composition and Function Are Altered by Reproductive State Molecular Carcinogenesis. Dec, 2004 | Pubmed ID: 15468292 Multistep Tumorigenesis and the Microenvironment Breast Cancer Research : BCR. 2004 | Pubmed ID: 14979914 ESX Induces Transformation and Functional Epithelial to Mesenchymal Transition in MCF-12A Mammary Epithelial Cells Oncogene. Mar, 2004 | Pubmed ID: 14767472 Adolescent Vitamin A Intake Alters Susceptibility to Mammary Carcinogenesis in the Sprague-Dawley Rat Nutrition and Cancer. 2002 | Pubmed ID: 12235654 A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer Erica T. Goddard1, Jacob Fischer1, Pepper Schedin1 1Department of Cell, Developmental and Cancer Biology, Oregon Health and Science University JoVE 54903 Ricerca sul cancro
A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer Erica T. Goddard1, Jacob Fischer1, Pepper Schedin1 1Department of Cell, Developmental and Cancer Biology, Oregon Health and Science University JoVE 54903 Ricerca sul cancro