Peter ten Dijke Dept. Cell Chemical Biology Leiden University Medical Center Biography Publications Institution JoVE Articles Peter ten Dijke has not added a biography. If you are Peter ten Dijke and would like to personalize this page please email our Author Liaison for assistance. Publications A Comprehensive Enhancer Screen Identifies TRAM2 As a Key and Novel Mediator of YAP Oncogenesis Genome Biology. Jan, 2021 | Pubmed ID: 33514403 E3 Ubiquitin Ligases: Key Regulators of TGFβ Signaling in Cancer Progression International Journal of Molecular Sciences. Jan, 2021 | Pubmed ID: 33418880 Targeting TGFβ Signal Transduction for Cancer Therapy Signal Transduction and Targeted Therapy. Jan, 2021 | Pubmed ID: 33414388 Therapeutic Targeting of TGF-β in Cancer: Hacking a Master Switch of Immune Suppression Clinical Science (London, England : 1979). Jan, 2021 | Pubmed ID: 33399850 Uncovering the Deubiquitinase Activity Landscape of Breast Cancer Oncoscience. Nov, 2020 | Pubmed ID: 33457450 TGF-β Signaling in Liver Metastasis Clinical and Translational Medicine. Nov, 2020 | Pubmed ID: 33252863 Designed Nanomolar Small-molecule Inhibitors of Ena/VASP EVH1 Interaction Impair Invasion and Extravasation of Breast Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. 11, 2020 | Pubmed ID: 33184177 Current Perspectives on Inhibitory SMAD7 in Health and Disease Critical Reviews in Biochemistry and Molecular Biology. Oct, 2020 | Pubmed ID: 33081543 Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos Journal of the American Chemical Society. Sep, 2020 | Pubmed ID: 32886496 Mechanotransduction is a Context-dependent Activator of TGF-β Signaling in Mesenchymal Stem Cells Biomaterials. Nov, 2020 | Pubmed ID: 32836056 Cercosporamide Inhibits Bone Morphogenetic Protein Receptor Type I Kinase Activity in Zebrafish Disease Models & Mechanisms. Sep, 2020 | Pubmed ID: 32820031 Reactivation of BMP Signaling by Suboptimal Concentrations of MEK Inhibitor and FK506 Reduces Organ-specific Breast Cancer Metastasis Cancer Letters. Nov, 2020 | Pubmed ID: 32768522 On-Target Anti-TGF-β Therapies Are Not Succeeding in Clinical Cancer Treatments: What Are Remaining Challenges? Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 32733895 Role of Glycosylation in TGF-β Signaling and Epithelial-to-mesenchymal Transition in Cancer Protein & Cell. Jun, 2020 | Pubmed ID: 32583064 Differential - and Glycosphingolipid Glycosylation in Human Pancreatic Adenocarcinoma Cells With Opposite Morphology and Metastatic Behavior Frontiers in Oncology. 2020 | Pubmed ID: 32582529 MnTBAP Reverses Pulmonary Vascular Remodeling and Improves Cardiac Function in Experimentally Induced Pulmonary Arterial Hypertension International Journal of Molecular Sciences. Jun, 2020 | Pubmed ID: 32531895 Bone Morphogenetic Protein Receptors: Structure, Function and Targeting by Selective Small Molecule Kinase Inhibitors Bone. Sep, 2020 | Pubmed ID: 32522605 Secreted BMP Antagonists and Their Role in Cancer and Bone Metastases Bone. Aug, 2020 | Pubmed ID: 32473315 TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 32373613 TGFβ and EGF Signaling Orchestrates the AP-1- and P63 Transcriptional Regulation of Breast Cancer Invasiveness Oncogene. May, 2020 | Pubmed ID: 32350443 Development of a 96-well Plate Sample Preparation Method for Integrated N- and O-glycomics Using Porous Graphitized Carbon Liquid Chromatography-mass Spectrometry Molecular Omics. 08, 2020 | Pubmed ID: 32281997 Immunotherapeutic Potential of TGF-β Inhibition and Oncolytic Viruses Trends in Immunology. 05, 2020 | Pubmed ID: 32223932 A Signaling Crosstalk Between BMP9 and HGF/c-Met Regulates Mouse Adult Liver Progenitor Cell Survival Cells. 03, 2020 | Pubmed ID: 32204446 Controlling Smad4 Signaling with a Wip EMBO Reports. 05, 2020 | Pubmed ID: 32189449 Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas Cancer Cell. 03, 2020 | Pubmed ID: 32142668 THG-1 Suppresses SALL4 Degradation to Induce Stemness Genes and Tumorsphere Formation Through Antagonizing NRBP1 in Squamous Cell Carcinoma Cells Biochemical and Biophysical Research Communications. 03, 2020 | Pubmed ID: 31864704 TGFβ-induced Metabolic Reprogramming During Epithelial-to-mesenchymal Transition in Cancer Cellular and Molecular Life Sciences : CMLS. Jun, 2020 | Pubmed ID: 31822964 Tacrolimus-Induced BMP/SMAD Signaling Associates With Metabolic Stress-Activated FOXO1 to Trigger β-Cell Failure Diabetes. 02, 2020 | Pubmed ID: 31732500 VprBP Mitigates TGF-β and Activin Signaling by Promoting Smurf1-mediated Type I Receptor Degradation Journal of Molecular Cell Biology. 02, 2020 | Pubmed ID: 31291647 Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva-Derived Endothelial Cells JBMR Plus. Nov, 2019 | Pubmed ID: 31768489 JNK-Dependent CJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses Cells. 11, 2019 | Pubmed ID: 31766464 A Perspective on the Development of TGF-β Inhibitors for Cancer Treatment Biomolecules. 11, 2019 | Pubmed ID: 31744193 Author Correction: C-Met Activation Leads to the Establishment of a TGFβ-receptor Regulatory Network in Bladder Cancer Progression Nature Communications. Nov, 2019 | Pubmed ID: 31704935 GREM1 is Associated with Metastasis and Predicts Poor Prognosis in ER-negative Breast Cancer Patients Cell Communication and Signaling : CCS. 11, 2019 | Pubmed ID: 31694641 C-Met Activation Leads to the Establishment of a TGFβ-receptor Regulatory Network in Bladder Cancer Progression Nature Communications. 09, 2019 | Pubmed ID: 31554791 Cancer-associated Fibroblast-derived Gremlin 1 Promotes Breast Cancer Progression Breast Cancer Research : BCR. 09, 2019 | Pubmed ID: 31533776 In Vivo Imaging of TGFβ Signalling Components Using Positron Emission Tomography Drug Discovery Today. 12, 2019 | Pubmed ID: 31494189 Role of Soluble Endoglin in BMP9 Signaling Proceedings of the National Academy of Sciences of the United States of America. 09, 2019 | Pubmed ID: 31431534 Prevention of Progression of Pulmonary Hypertension by the Nur77 Agonist 6-mercaptopurine: Role of BMP Signalling The European Respiratory Journal. 09, 2019 | Pubmed ID: 31273046 Autophagy Contributes to BMP Type 2 Receptor Degradation And development of Pulmonary Arterial Hypertension The Journal of Pathology. 11, 2019 | Pubmed ID: 31257577 Generation of Non-standard Macrocyclic Peptides Specifically Binding TSC-22 Homologous Gene-1 Biochemical and Biophysical Research Communications. 08, 2019 | Pubmed ID: 31227214 TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis International Journal of Molecular Sciences. Jun, 2019 | Pubmed ID: 31195692 Epigenetic Reprogramming of TGF-β Signaling in Breast Cancer Cancers. May, 2019 | Pubmed ID: 31137748 Combined Inhibition of TGF-β Signaling and the PD-L1 Immune Checkpoint Is Differentially Effective in Tumor Models Cells. 04, 2019 | Pubmed ID: 30959852 TGF-β Family Signaling Pathways in Cellular Dormancy Trends in Cancer. 01, 2019 | Pubmed ID: 30616757 Inflammation Induces Endothelial-to-mesenchymal Transition and Promotes Vascular Calcification Through Downregulation of BMPR2 The Journal of Pathology. 03, 2019 | Pubmed ID: 30430573 Bone Morphogenetic Protein Receptor Signal Transduction in Human Disease The Journal of Pathology. 01, 2019 | Pubmed ID: 30246251 The Therapeutic Potential of Targeting the Endothelial-to-mesenchymal Transition Angiogenesis. 02, 2019 | Pubmed ID: 30076548 Epithelial-mesenchymal-transition-inducing Transcription Factors: New Targets for Tackling Chemoresistance in Cancer? Oncogene. 11, 2018 | Pubmed ID: 30002444 Endoglin Expression on Cancer-Associated Fibroblasts Regulates Invasion and Stimulates Colorectal Cancer Metastasis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 12, 2018 | Pubmed ID: 29945992 Bone Morphogenetic Protein 9 As a Key Regulator of Liver Progenitor Cells in DDC-induced Cholestatic Liver Injury Liver International : Official Journal of the International Association for the Study of the Liver. 09, 2018 | Pubmed ID: 29751359 TGF-β Family Co-receptor Function and Signaling Acta Biochimica Et Biophysica Sinica. Jan, 2018 | Pubmed ID: 29293886 JUNB Governs a Feed-forward Network of TGFβ Signaling That Aggravates Breast Cancer Invasion Nucleic Acids Research. 02, 2018 | Pubmed ID: 29186616 Endothelial-to-mesenchymal Transition in Cardiovascular Diseases: Developmental Signaling Pathways Gone Awry Developmental Dynamics : an Official Publication of the American Association of Anatomists. 03, 2018 | Pubmed ID: 28891150 Breast Cancer Metastasis Suppressor OTUD1 Deubiquitinates SMAD7 Nature Communications. 12, 2017 | Pubmed ID: 29235476 TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases International Journal of Molecular Sciences. Oct, 2017 | Pubmed ID: 29039786 Disparate Phospho-Smad2 Levels in Advanced Type 2 Diabetes Patients with Diabetic Nephropathy and Early Experimental Db/db Mouse Model Renal Failure. Nov, 2017 | Pubmed ID: 28805484 Bone Morphogenetic Protein 9 Protects Against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation Frontiers in Physiology. 2017 | Pubmed ID: 28751863 Targeting TGF-β Signaling in Cancer Trends in Cancer. 01, 2017 | Pubmed ID: 28718426 SUMO-triggered Ubiquitination of NR4A1 Controls Macrophage Cell Death Cell Death and Differentiation. 09, 2017 | Pubmed ID: 28622293 TGFβ1-induced SMAD2/3 and SMAD1/5 Phosphorylation Are Both ALK5-kinase-dependent in Primary Chondrocytes and Mediated by TAK1 Kinase Activity Arthritis Research & Therapy. May, 2017 | Pubmed ID: 28569204 Erratum To: BMP Type II Receptor As a Therapeutic Target in Pulmonary Arterial Hypertension Cellular and Molecular Life Sciences : CMLS. 08, 2017 | Pubmed ID: 28536788 USP4 Inhibits SMAD4 Monoubiquitination and Promotes Activin and BMP Signaling The EMBO Journal. 06, 2017 | Pubmed ID: 28468752 BMP Type II Receptor As a Therapeutic Target in Pulmonary Arterial Hypertension Cellular and Molecular Life Sciences : CMLS. 08, 2017 | Pubmed ID: 28447104 FAF1 Phosphorylation by AKT Accumulates TGF-β Type II Receptor and Drives Breast Cancer Metastasis Nature Communications. 04, 2017 | Pubmed ID: 28443643 Bone Morphogenetic Proteins in Vascular Homeostasis and Disease Cold Spring Harbor Perspectives in Biology. Mar, 2017 | Pubmed ID: 28348038 TGF-β Signaling in Control of Cardiovascular Function Cold Spring Harbor Perspectives in Biology. Mar, 2017 | Pubmed ID: 28348036 BMP-9 Interferes with Liver Regeneration and Promotes Liver Fibrosis Gut. May, 2017 | Pubmed ID: 28336518 Fluid Shear Stress-induced TGF-β/ALK5 Signaling in Renal Epithelial Cells is Modulated by MEK1/2 Cellular and Molecular Life Sciences : CMLS. Feb, 2017 | Pubmed ID: 28168444 TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation The Journal of Biological Chemistry. Mar, 2017 | Pubmed ID: 28115518 Smad2 Phosphorylation in Diabetic Kidney Tubule Epithelial Cells Is Associated with Modulation of Several Transforming Growth Factor-β Family Members Nephron. 2017 | Pubmed ID: 28064277 New Function of the Myostatin/activin Type I Receptor (ALK4) As a Mediator of Muscle Atrophy and Muscle Regeneration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2017 | Pubmed ID: 27733450 Fish Tales: The Use of Zebrafish Xenograft Human Cancer Cell Models Histology and Histopathology. Dec, 2016 | Pubmed ID: 27933602 Immunoregulation by Members of the TGFβ Superfamily Nature Reviews. Immunology. 11, 2016 | Pubmed ID: 27885276 Towards a Cure for Fibrodysplasia Ossificans Progressiva Annals of Translational Medicine. Oct, 2016 | Pubmed ID: 27867996 Mutational Activation of BRAF Confers Sensitivity to Transforming Growth Factor Beta Inhibitors in Human Cancer Cells Oncotarget. Dec, 2016 | Pubmed ID: 27835901 Targeting Tumour Vasculature by Inhibiting Activin Receptor-like Kinase (ALK)1 Function Biochemical Society Transactions. Aug, 2016 | Pubmed ID: 27528762 A Current Perspective on Applications of Macrocyclic-peptide-based High-affinity Ligands Biopolymers. Nov, 2016 | Pubmed ID: 27352774 C-Myb Enhances Breast Cancer Invasion and Metastasis Through the Wnt/β-Catenin/Axin2 Pathway Cancer Research. Jun, 2016 | Pubmed ID: 27197202 Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression The American Journal of Pathology. Jul, 2016 | Pubmed ID: 27171900 Regulation of the TGF-β Pathway by Deubiquitinases in Cancer The International Journal of Biochemistry & Cell Biology. Jul, 2016 | Pubmed ID: 27155333 Smad6 Determines BMP-regulated Invasive Behaviour of Breast Cancer Cells in a Zebrafish Xenograft Model Scientific Reports. Apr, 2016 | Pubmed ID: 27113436 Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease Journal of the American Society of Nephrology : JASN. Dec, 2016 | Pubmed ID: 27020852 Emerging Regulators of BMP Bioavailability Bone. Dec, 2016 | Pubmed ID: 26825814 The Rationale for Targeting TGF-β in Chronic Liver Diseases European Journal of Clinical Investigation. Apr, 2016 | Pubmed ID: 26823073 TGF-β Signalling and Liver Disease The FEBS Journal. Jun, 2016 | Pubmed ID: 26807763 Interrogating TGF-β Function and Regulation in Endothelial Cells Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26520125 Determining TGF-β Receptor Levels in the Cell Membrane Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26520116 In Brief: Endothelial-to-mesenchymal Transition The Journal of Pathology. Feb, 2016 | Pubmed ID: 26446982 Regulatory RNAs Controlling Vascular (dys)function by Affecting TGF-ß Family Signalling EXCLI Journal. 2015 | Pubmed ID: 26862319 Signal Transduction: Gain of Activin Turns Muscle into Bone Current Biology : CB. Dec, 2015 | Pubmed ID: 26654374 Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva Stem Cell Reports. Dec, 2015 | Pubmed ID: 26626181 Targeting BMP Signalling in Cardiovascular Disease and Anaemia Nature Reviews. Cardiology. Oct, 2015 | Pubmed ID: 26461965 Bone Morphogenetic Protein 6 and Oxidized Low-density Lipoprotein Synergistically Recruit Osteogenic Differentiation in Endothelial Cells Cardiovascular Research. Nov, 2015 | Pubmed ID: 26410368 Heterozygous Disruption of Activin Receptor-like Kinase 1 is Associated with Increased Arterial Pressure in Mice Disease Models & Mechanisms. Nov, 2015 | Pubmed ID: 26398936 Activin Receptor-like Kinase 1 Ligand Trap Reduces Microvascular Density and Improves Chemotherapy Efficiency to Various Solid Tumors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2015 | Pubmed ID: 26373572 Bone Morphogenetic Protein Signaling in Bone Homeostasis Bone. Nov, 2015 | Pubmed ID: 26051467 A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins Journal of Virology. Aug, 2015 | Pubmed ID: 26041291 Genetic Depletion and Pharmacological Targeting of αv Integrin in Breast Cancer Cells Impairs Metastasis in Zebrafish and Mouse Xenograft Models Breast Cancer Research : BCR. Feb, 2015 | Pubmed ID: 25849225 Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2 Gastroenterology. Jun, 2015 | Pubmed ID: 25736321 14-3-3ζ Turns TGF-β to the Dark Side Cancer Cell. Feb, 2015 | Pubmed ID: 25670073 SLUG is Expressed in Endothelial Cells Lacking Primary Cilia to Promote Cellular Calcification Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2015 | Pubmed ID: 25633317 Clinical Utility Gene Card For: Fibrodysplasia Ossificans Progressiva European Journal of Human Genetics : EJHG. Oct, 2015 | Pubmed ID: 25604857 Inhibition of TGFβ Type I Receptor Activity Facilitates Liver Regeneration Upon Acute CCl4 Intoxication in Mice Archives of Toxicology. Jan, 2015 | Pubmed ID: 25566828 Ter94/VCP is a Novel Component Involved in BMP Signaling PloS One. 2014 | Pubmed ID: 25469707 Wild-type P53 Inhibits Pro-invasive Properties of TGF-β3 in Breast Cancer, in Part Through Regulation of EPHB2, a New TGF-β Target Gene Breast Cancer Research and Treatment. Nov, 2014 | Pubmed ID: 25257729 Assessment of Functional Competence of Endothelial Cells from Human Pluripotent Stem Cells in Zebrafish Embryos Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 25173378 Time-resolved Dissection of Early Phosphoproteome and Ensuing Proteome Changes in Response to TGF-β Science Signaling. Jul, 2014 | Pubmed ID: 25056879 Generation, Expansion and Functional Analysis of Endothelial Cells and Pericytes Derived from Human Pluripotent Stem Cells Nature Protocols. 2014 | Pubmed ID: 24874816 Loss of SMAD4 Alters BMP Signaling to Promote Colorectal Cancer Cell Metastasis Via Activation of Rho and ROCK Gastroenterology. Jul, 2014 | Pubmed ID: 24704720 Targeting TGF-β Signaling by Antisense Oligonucleotide-mediated Knockdown of TGF-β Type I Receptor Molecular Therapy. Nucleic Acids. Apr, 2014 | Pubmed ID: 24691207 Nuclear Receptor NR4A1 Promotes Breast Cancer Invasion and Metastasis by Activating TGF-β Signalling Nature Communications. 2014 | Pubmed ID: 24584437 ENDOGLIN is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-induced Angiogenesis PloS One. 2014 | Pubmed ID: 24489709 Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides Molecular Therapy. Nucleic Acids. 2014 | Pubmed ID: 24448195 Functionality of Endothelial Cells and Pericytes from Human Pluripotent Stem Cells Demonstrated in Cultured Vascular Plexus and Zebrafish Xenografts Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2014 | Pubmed ID: 24158517 Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-knot for Wnt-signaling Inhibition PloS One. 2013 | Pubmed ID: 24312339 Signaling Interplay Between Transforming Growth Factor-β Receptor and PI3K/AKT Pathways in Cancer Trends in Biochemical Sciences. Dec, 2013 | Pubmed ID: 24239264 Transforming Growth Factor-β Signalling Controls Human Breast Cancer Metastasis in a Zebrafish Xenograft Model Breast Cancer Research : BCR. Nov, 2013 | Pubmed ID: 24196484 Activin Receptor-like Kinase 1 As a Target for Anti-angiogenesis Therapy Expert Opinion on Investigational Drugs. Nov, 2013 | Pubmed ID: 24053899 Transforming Growth Factor-β (TGF-β)-mediated Connective Tissue Growth Factor (CTGF) Expression in Hepatic Stellate Cells Requires Stat3 Signaling Activation The Journal of Biological Chemistry. Oct, 2013 | Pubmed ID: 24005672 TRAF4 Promotes TGF-β Receptor Signaling and Drives Breast Cancer Metastasis Molecular Cell. Sep, 2013 | Pubmed ID: 23973329 FK506 Activates BMPR2, Rescues Endothelial Dysfunction, and Reverses Pulmonary Hypertension The Journal of Clinical Investigation. Aug, 2013 | Pubmed ID: 23867624 Antisense-oligonucleotide Mediated Exon Skipping in Activin-receptor-like Kinase 2: Inhibiting the Receptor That is Overactive in Fibrodysplasia Ossificans Progressiva PloS One. 2013 | Pubmed ID: 23861958 Three-dimensional Co-cultures of Human Endothelial Cells and Embryonic Stem Cell-derived Pericytes Inside a Microfluidic Device Lab on a Chip. Sep, 2013 | Pubmed ID: 23702711 Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-mediated Antagonism of Wnt/LRP6 Signaling PloS One. 2013 | Pubmed ID: 23638027 Snail and Slug, Key Regulators of TGF-β-induced EMT, Are Sufficient for the Induction of Single-cell Invasion Biochemical and Biophysical Research Communications. May, 2013 | Pubmed ID: 23618854 Preventive and Therapeutic Effects of Smad7 on Radiation-induced Oral Mucositis Nature Medicine. Apr, 2013 | Pubmed ID: 23475202 Fine-tuning BMP7 Signalling in Adipogenesis by UBE2O/E2-230K-mediated Monoubiquitination of SMAD6 The EMBO Journal. Apr, 2013 | Pubmed ID: 23455153 Deficiency for Endoglin in Tumor Vasculature Weakens the Endothelial Barrier to Metastatic Dissemination The Journal of Experimental Medicine. Mar, 2013 | Pubmed ID: 23401487 UBE2O Negatively Regulates TRAF6-mediated NF-κB Activation by Inhibiting TRAF6 Polyubiquitination Cell Research. Mar, 2013 | Pubmed ID: 23381138 Endoglin for Tumor Imaging and Targeted Cancer Therapy Expert Opinion on Therapeutic Targets. Apr, 2013 | Pubmed ID: 23327677 Overactive Bone Morphogenetic Protein Signaling in Heterotopic Ossification and Duchenne Muscular Dystrophy Cellular and Molecular Life Sciences : CMLS. Feb, 2013 | Pubmed ID: 22752156 Soluble Fms-like Tyrosine Kinase 1 and Soluble Endoglin Are Elevated Circulating Anti-angiogenic Factors in Pre-eclampsia Pregnancy Hypertension. Oct, 2012 | Pubmed ID: 26105603 MicroRNA-155 Functions As a Negative Regulator of RhoA Signaling in TGF-β-induced Endothelial to Mesenchymal Transition MicroRNA (Shariqah, United Arab Emirates). 2012 | Pubmed ID: 25048084 만성 간 질환의 동물 모델입니다 American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2012 | Pubmed ID: 23275613 MED12 Controls the Response to Multiple Cancer Drugs Through Regulation of TGF-β Receptor Signaling Cell. Nov, 2012 | Pubmed ID: 23178117 The Activities of Smad and Gli Mediated Signalling Pathways in High-grade Conventional Osteosarcoma European Journal of Cancer (Oxford, England : 1990). Dec, 2012 | Pubmed ID: 22868198 Fas-associated Factor 1 is a Scaffold Protein That Promotes β-transducin Repeat-containing Protein (β-TrCP)-mediated β-catenin Ubiquitination and Degradation The Journal of Biological Chemistry. Aug, 2012 | Pubmed ID: 22730322 TGF-β Signalling and Its Role in Cancer Progression and Metastasis Cancer Metastasis Reviews. Dec, 2012 | Pubmed ID: 22714591 BMP Signaling in Vascular Diseases FEBS Letters. Jul, 2012 | Pubmed ID: 22710160 USP4 is Regulated by AKT Phosphorylation and Directly Deubiquitylates TGF-β Type I Receptor Nature Cell Biology. Jun, 2012 | Pubmed ID: 22706160 TGFβ Signaling in Liver Regeneration Current Pharmaceutical Design. 2012 | Pubmed ID: 22630085 Deregulated Bone Morphogenetic Protein Receptor Signaling Underlies Fibrodysplasia Ossificans Progressiva Current Pharmaceutical Design. 2012 | Pubmed ID: 22630080 Role of Endoglin in Fibrosis and Scleroderma International Review of Cell and Molecular Biology. 2012 | Pubmed ID: 22608563 LRP8 Mediates Wnt/β-catenin Signaling and Controls Osteoblast Differentiation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2012 | Pubmed ID: 22589174 RNF12 Controls Embryonic Stem Cell Fate and Morphogenesis in Zebrafish Embryos by Targeting Smad7 for Degradation Molecular Cell. Jun, 2012 | Pubmed ID: 22560923 Anti-human Activin Receptor-like Kinase 1 (ALK1) Antibody Attenuates Bone Morphogenetic Protein 9 (BMP9)-induced ALK1 Signaling and Interferes with Endothelial Cell Sprouting The Journal of Biological Chemistry. May, 2012 | Pubmed ID: 22493445 Shear Induced Collateral Artery Growth Modulated by Endoglin but Not by ALK1 Journal of Cellular and Molecular Medicine. Oct, 2012 | Pubmed ID: 22436015 Vanilloid Receptor-1 Regulates Neurogenic Inflammation in Colon and Protects Mice from Colon Cancer Cancer Research. Apr, 2012 | Pubmed ID: 22396497 TGF-β Signaling in Endothelial-to-mesenchymal Transition: the Role of Shear Stress and Primary Cilia Science Signaling. Feb, 2012 | Pubmed ID: 22355187 유비퀴틴 단백질 수정 TGFβ 신호 전달에 중요 한 역할 Upsala Journal of Medical Sciences. Feb, 2012 | Pubmed ID: 22335355 Wnt/β-catenin 신호 Id3 식을 유도 하 여 C2C12 Myoblast 증식과 분화를 변경 합니다 Biochemical and Biophysical Research Communications. Feb, 2012 | Pubmed ID: 22326917 키 노드 유선 개발 및 암 신호: 상피 세포가 소성에서 Smad 신호 통합 Breast Cancer Research : BCR. Feb, 2012 | Pubmed ID: 22315972 炭 Dimerized 재조합 인간 뼈 전체적 단백질 15 변종 식별 뼈 전체적 단백질 수용 체 난소 Granulosa 셀에 주요 세포 표면 수용 체로 1b를 입력 합니다 Endocrinology. Jan, 2012 | Pubmed ID: 22294741 선 천 성 심장 혈관 기형 SMAD6 유전자에 있는 비 동의어 이체 Predispose Human Mutation. Jan, 2012 | Pubmed ID: 22275001 유비퀴틴 특정 단백질 4 수신자-처럼/interleukin 1 수용 체 신호를 완화 하 고 타고 난 면역 활성화를 조절 The Journal of Biological Chemistry. Jan, 2012 | Pubmed ID: 22262844 TGFβ 신호 및 심장 혈관 질병입니다 International Journal of Biological Sciences. 2012 | Pubmed ID: 22253564 TGF-β 간 질환의 진행에 Cell and Tissue Research. Jan, 2012 | Pubmed ID: 22006249 BMP-7 Integrin β(3) 식의 억제를 통해 유방암 세포의 TGF-β 유도 침략을 억제 한다 Cellular Oncology (Dordrecht). Feb, 2012 | Pubmed ID: 21935711 내 피 세포가 소성 TGF-β에 의해 규제 Cell and Tissue Research. Jan, 2012 | Pubmed ID: 21866313 골 관절염에서 TGF-β 신호 전달의 연령에 따라 변경 합니다 Cell and Tissue Research. Jan, 2012 | Pubmed ID: 21638205 TGF-β에 의해 내 피 장벽 기능의 규제 나 수용 체 ALK5 입력: 수축 메커니즘 및 열 충격 단백질 90의 잠재적인 역할 Journal of Cellular Physiology. Feb, 2012 | Pubmed ID: 21465483 셀 타입 Myostatin 시그널링의 특정 규정입니다 The FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2011 | Pubmed ID: 22202673 마우스 표 피에서 임시 Smad7 Transgene 유도 피부 상처 치유 촉진 The American Journal of Pathology. Oct, 2011 | Pubmed ID: 21944279 GSK3β 비활성화 C Myb의 기능을 억압 하 여 백혈병 세포의 Apoptosis를 유도 합니다 Molecular Biology of the Cell. Sep, 2011 | Pubmed ID: 21795403 두 개의 독특한 TGF-β에 의해 제어 신생 나 수용 체 신호 경로 입력 합니다 Histology and Histopathology. Sep, 2011 | Pubmed ID: 21751154 암 및 섬유 증 요법 안티-TGF-β를 탐험 Growth Factors (Chur, Switzerland). Aug, 2011 | Pubmed ID: 21718111 변형 성장 인자 높은 β와 물질 활성화 한 단백질 키 니 아 제 경로 중재 Dupuytren의 질병 게재 Fibrotic 특성 Fibrogenesis & Tissue Repair. 2011 | Pubmed ID: 21711521 TGF-β 수용 체 신호 경로에 신생; 안티-혈관 신생 치료에 대 한 새로운 목표입니다 Current Pharmaceutical Biotechnology. May, 2011 | Pubmed ID: 21619534 변형 성장 인자 β 뼈 전체적 단백질을 이용한 Osteoblast 차별화에의 영향을 나아졌다 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2011 | Pubmed ID: 21611961 Tgfβ/Alk5 신호 하는 것은 배아 내 피 세포에서 유도 된 전단 응력 Klf2 식에 대 한 필요 합니다 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jul, 2011 | Pubmed ID: 21604321 듀얼 Exon Myostatin Dystrophin Duchenne 근 위축 증에 대 한에 마 찮 가지 야 BMC Medical Genomics. 2011 | Pubmed ID: 21507246 TGF-β 신호 유 방 암 세포 침입과 뼈 전이에 Journal of Mammary Gland Biology and Neoplasia. Jun, 2011 | Pubmed ID: 21494783 TGF-β1/ALK5-유도 Monocyte 마이그레이션 PI3K 및 P38 경로 포함 하 고 당뇨병 Mellitus에 의해 부정적인 영향을 받지 않습니다 Cardiovascular Research. Aug, 2011 | Pubmed ID: 21478266 Fas 관련 요인 1 β-catenin 저하를 촉진 하 여 Wnt 신호 반감 Molecular Biology of the Cell. May, 2011 | Pubmed ID: 21411632 기본 속눈썹의 부족-내 피-엽 전환 전단 유도 소수 Circulation Research. Apr, 2011 | Pubmed ID: 21393577 Endoglin Scleroderma 섬유 아 세포에서 TGF-β/Smad1 신호를 촉진 합니다 Journal of Cellular Physiology. Dec, 2011 | Pubmed ID: 21344387 다운 증후군 및 선 천 성 심장 환자의 ALK2 돌연변이 제거 European Journal of Human Genetics : EJHG. Apr, 2011 | Pubmed ID: 21248739 TGFbeta 물질과 스트레스 활성화 단백질 키 니 아 제-1 (MSK1) 세포 죽음 감쇠를 활성화 합니다 The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21106525 암에 TGF-β의 동적 역할 The Journal of Pathology. Jan, 2011 | Pubmed ID: 20957627 Activin A TGF-β는 달리 부드러운 근육 세포에 있는 비 Fibrotic 형을 유도합니다 Experimental Cell Research. Jan, 2011 | Pubmed ID: 20955695 BMP 길 항 제 Myogenic 차별화를 강화 하 고 개량 DMD 마우스 모델에서 Dystrophic 표현 형 Neurobiology of Disease. Feb, 2011 | Pubmed ID: 20940052 TGF-β/Smad 통로 팽창이 침공 모델 시스템에서 매트릭스 Metalloproteinase 2와 9의 업 레 귤 레이 션을 통해 유 방 암 세포 침공을 유도합니다 Breast Cancer Research and Treatment. Aug, 2011 | Pubmed ID: 20821046 나아졌다 변형 성장 인자-β 전체적 뼈에 단백질을 이용한 Osteoblast 차별화의 효과 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Dec, 2010 | Pubmed ID: 21162084 BMP의 제정 활동의 측정에는 수용 체 유형 I Methods in Enzymology. 2010 | Pubmed ID: 21036238 뼈 전체적 단백질과 Wnt 신호 경로에 Sclerostin에 의해 저해의 고유 모드 The Journal of Biological Chemistry. Dec, 2010 | Pubmed ID: 20952383 혈관 Morphogenesis와 질병에서 TGF-베타 가족의 구성원에 의해 신호입니다 Trends in Cell Biology. Sep, 2010 | Pubmed ID: 20656490 종양 세포 침 윤 성 앞에 Transcriptional 신호의 통합 Cell Cycle (Georgetown, Tex.). Jul, 2010 | Pubmed ID: 20647778 TGFbeta Smad 신호 실험 Pkd1 모델과 인간의 Polycystic 신장 질환 환자에서 높은 The Journal of Pathology. Sep, 2010 | Pubmed ID: 20549648 현장에서 근접 결 찰 탐지 AP 1 C 6 월 이합체의 적극적인 유 방 암 세포 선 생체 외 및 생체 조건에서 C-6 월/Fra1 단지의 증가 수준을 보여준다 Molecular & Cellular Proteomics : MCP. Sep, 2010 | Pubmed ID: 20511396 매트릭스 Metalloproteinase-14 (MT1 MMP)-종양 혈관 신생을 억제 중재 Endoglin 흘리기 Cancer Research. May, 2010 | Pubmed ID: 20424116 A1 Annexin TGF-베타 신호 조절 및 기저 같은 유방암 세포의 전이 형성을 촉진 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20308542 TMEPAI, 막 횡단 TGF-베타-유도할 수 있는 단백질 Sequesters Smad 단백질 TGF-베타 신호에 적극적으로 참여에서 Molecular Cell. Jan, 2010 | Pubmed ID: 20129061 종양의 성장 및 신생 손상 유전자 및 약리 Activin 수용 체와 같은 키 니 아 제 1의 대상 The Journal of Experimental Medicine. Jan, 2010 | Pubmed ID: 20065063 중재 뼈 전체적 단백질 (BMP)-6 키 잔류물의 탁월한 길 항 제 활동 설계 Bmps를 고려한 머리 저해에 대 한 저항 The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20048150 ALK2 R206H 돌연변이 Fibrodysplasia 염증 Progressiva 연결할 수 여 BMP 제정 활동 유형 I 수용 체 및 BMP 유도 Osteoblast 차별화와 뼈 형성에 중간 엽 세포를 Sensitizes Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2010 | Pubmed ID: 19929436 5-Aminosalicylic 산 TGF Beta1 Colorectal 암 세포에서 신호를 억제 한다 Cancer Letters. Jan, 2010 | Pubmed ID: 19541409 난소 암 세포 증식을 촉진 Activin 수용 체와 같은 니-2/Smad1/smad4를 통해 Autocrine 뼈 전체적 단백질-9 신호 Cancer Research. Dec, 2009 | Pubmed ID: 19996292 VEGF와 TGFbeta 억제제 입력-난 수용 체 니 Synergistically Alpha5 Integrin 식 유도-혈관 형성을 촉진 합니다 Journal of Cell Science. Sep, 2009 | Pubmed ID: 19706683 Smad3는 성장 인자 베타 Nme 마우스 유 방 상피 세포에서 신호 변환 키 비중복 중재자입니다 Molecular Cancer Research : MCR. Aug, 2009 | Pubmed ID: 19671686 Endoglin Haploinsufficiency 마우스 신장에서 방사선을 이용한 섬유 증 및 Telangiectasia 형성을 감소 시킨다 Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Sep, 2009 | Pubmed ID: 19576647 선 천 성 심장 결함 지배 음수가 ALK2 대립 유전자에 연결합니다 Circulation. Jun, 2009 | Pubmed ID: 19506109 성장 인자-베타 신호 및 종양 혈관 신생을 변형 Frontiers in Bioscience : a Journal and Virtual Library. 2009 | Pubmed ID: 19482591 노크에 쥐 L45 루프 돌연변이 Smad 활성화 기능에 결함이 있는 ALK5 표현에서 배아에서 불 쌍 한 혈관 형성 Laboratory Investigation; a Journal of Technical Methods and Pathology. Jul, 2009 | Pubmed ID: 19398960 전리 방사선 파이 1/ID 1 균형을 교대 하 고 노치 내 피 세포에 신호를 활성화 합니다 International Journal of Radiation Oncology, Biology, Physics. Feb, 2009 | Pubmed ID: 19147015 TGF-베타 혈관 생물학 및 부전 신호 Cell Research. Jan, 2009 | Pubmed ID: 19114994 스키 Co-repressor 단지 Hdac3와 Prmt5를 통해 SMAD7, TGF-베타 대상 유전자의 기저 억압 된 상태를 유지 합니다 Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Jan, 2009 | Pubmed ID: 19032343 변형 성장 인자 베타 유도 내 피 대 엽 전환: 심장 섬유 증에 스위치? Trends in Cardiovascular Medicine. Nov, 2008 | Pubmed ID: 19345316 Smad1 통로 조직의 경화 증 섬유 아 세포에서 활성화 되 고 Imatinib Mesylate 대상 이다 Arthritis and Rheumatism. Aug, 2008 | Pubmed ID: 18668566 뼈 전체적 단백질 통로 산발적 대 장 암의 대다수에서 비활성화 됩니다 Gastroenterology. May, 2008 | Pubmed ID: 18471510 VE Cadherin TGF-베타 신호 전달의 중요 한 내 피 레 귤 레이 터 이다 The EMBO Journal. Apr, 2008 | Pubmed ID: 18337748 ALK1 ALK5/Smad3 신호 및 인간의 Chondrocytes에서 세포 외 기질 컴포넌트의 표현에 반대 한다 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2008 | Pubmed ID: 18333754 L S Endoglin 차동 Tgfbeta1이 중재 Alk1와 ALK5 L6E9 Myoblasts에 신호 변조 Journal of Cell Science. Mar, 2008 | Pubmed ID: 18303046 골 형성을 억제 하는 Osteocyte에서 파생 된 Sclerostin: 뼈 전체적 단백질 및 Wnt 신호 전달에서 역할 The Journal of Bone and Joint Surgery. American Volume. Feb, 2008 | Pubmed ID: 18292354 신생과 혈관 질환에서 Endoglin입니다 Angiogenesis. 2008 | Pubmed ID: 18283546 두 소설 유형 II 수용 체 BMP 신호 중재와 Zebrafish의 좌우 비대칭을 확립 하는 데 필요한 Developmental Biology. Mar, 2008 | Pubmed ID: 18222420 변형 성장 인자 베타 및 상처 치유 인간의 Cholesteatoma The Laryngoscope. Jan, 2008 | Pubmed ID: 17989584 쥐에서 TGFbeta 수용 체의 삭제로 노 른 자 Sac 혈관에서 유도 된 보상 신호 Journal of Cell Science. Dec, 2007 | Pubmed ID: 18029401 종양의 진행과 뼈 전이에 TGF-베타와 BMP7 상호 작용 Clinical & Experimental Metastasis. 2007 | Pubmed ID: 18008174 세포 외 제어 TGFbeta 혈관 개발 및 질병에 있는 신호 Nature Reviews. Molecular Cell Biology. Nov, 2007 | Pubmed ID: 17895899 신속 하 고 민감한 Bioassay 뼈 전체적 단백질 활동을 측정 합니다 BMC Cell Biology. 2007 | Pubmed ID: 17880711 Morphogenetic 단백질 7 개발부터 유방암 뼈 전이의 치료에서 뼈 Cancer Research. Sep, 2007 | Pubmed ID: 17875715 BMP7, 인간의 전립선 상피 항상성의 상 레 귤 레이 터 전립선 암 뼈 전이 Vivo에서의 강력한 억제제 이다 The American Journal of Pathology. Sep, 2007 | Pubmed ID: 17724140 성장 인자-베타를 변형 하 여 소닉 헤 지 호 그 중재자의 유도: 생체 외 및 생체 조건 Gli2 및 Gli1 식의 Smad3 종속 활성화 Cancer Research. Jul, 2007 | Pubmed ID: 17638910 내 피 세포에서 TGF-베타 유도 외 1 식 중재 ALK5 여 신호: 마이그레이션 및 확산에 대 한 역할 Journal of Cell Science. Apr, 2007 | Pubmed ID: 17376964 변형 성장 인자-베타 수용 체 타입-종속 Fibrogenic 유전자 프로그램 Smad1 및 ERK1/2 통로의 활성화를 통해 중재 됩니다 The Journal of Biological Chemistry. Apr, 2007 | Pubmed ID: 17317656 TGF-베타 수용 체/Smad 신호 전달의 부정적인 레 귤 레이 션 Current Opinion in Cell Biology. Apr, 2007 | Pubmed ID: 17317136 Aberrant Bmp Signaling and Notochord Delamination in the Pathogenesis of Esophageal Atresia Developmental Dynamics : an Official Publication of the American Association of Anatomists. Mar, 2007 | Pubmed ID: 17260385 SOST 식 배아 및 신생아 심장 혈관 개발 하는 동안 큰 동맥으로 제한 됩니다 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Feb, 2007 | Pubmed ID: 17195180 KLF2 TGF-베타 Smad7의 유도 및 AP-1의 억제를 통해 Endothelium에 신호를 표시 하지 않습니다 Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2007 | Pubmed ID: 17194892 Wnt 하지만 하지 BMP BMP 자극 뼈 형성에는 Sclerostin의 금지 조치에 관여 하는 신호 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jan, 2007 | Pubmed ID: 17032150 메 틸의 Smad6 단백질 아르기닌 N-methyltransferase 1 FEBS Letters. Dec, 2006 | Pubmed ID: 17118358 Endoglin 피 셀 중재 혈관 복구에 중요 한 역할을 하고있다 Circulation. Nov, 2006 | Pubmed ID: 17088457 속도 방정식 접근의 속도 론 및 TGF-베타 통로의 견고 하 Biophysical Journal. Dec, 2006 | Pubmed ID: 17012329 Smad7을 이용한 베타-catenin 저하 상피 돌출부 개발을 변경합니다 Developmental Cell. Sep, 2006 | Pubmed ID: 16950122 Id1 쥐 간장 주문과 세포의 TGF-베타 유도 Transdifferentiation에서 중요 한 중재자 이다 Hepatology (Baltimore, Md.). May, 2006 | Pubmed ID: 16628634 Smad7 및 단백질 인산 가수분해 효소 1alpha 내 피 세포에서 TGF-베타/ALK1 신호 기간에 중요 한 결정 요인입니다 BMC Cell Biology. 2006 | Pubmed ID: 16571110 종양 억제기 Smad4가 변형 성장 인자 베타 유도 하 엽 상피 전환 및 유방암 세포의 뼈 전이 필요 합니다 Cancer Research. Feb, 2006 | Pubmed ID: 16489022 신생과 혈관 장애에 변형 성장 인자-베타 신호 변환 Chest. Dec, 2005 | Pubmed ID: 16373850 Deubiquitinating 효소 UCH37 Smads 상호 작용 하는 TGF-베타 신호 규제 하 고 있습니다 Oncogene. Dec, 2005 | Pubmed ID: 16027725 Smad2/3 종속 TGF-베타 신호 살아있는 생쥐에서의 글로벌 분석 부상 눈에 띄는 조직 특정 응답을 보여준다 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2005 | Pubmed ID: 15972691 뼈 변형 성장 인자 Beta1입니다 Endocrine Reviews. Oct, 2005 | Pubmed ID: 15901668 SOST/sclerostin, 뼈 형성의 Osteocyte에서 파생 된 부정적인 조정기를 Cytokine & Growth Factor Reviews. Jun, 2005 | Pubmed ID: 15869900 피부 타고 난 면제의 새로운 메커니즘: ASK1 중재 Keratinocyte 분화 조절 베타 Defensins, LL37, 및 TLR2 표현 European Journal of Immunology. Jun, 2005 | Pubmed ID: 15864780 TGF-베타 수용 체 기능 Endothelium에서 Cardiovascular Research. Feb, 2005 | Pubmed ID: 15664386 Endoglin 돌연변이 생쥐의 노 른 자 Sac 혈관에 Tgfbeta에 의해 신호 결함이 Paracrine: 유전 Haemorrhagic Telangiectasia 패러다임 Development (Cambridge, England). Dec, 2004 | Pubmed ID: 15548578 Endoglin 내 피 세포 증식 및 TGF-베타/ALK1 신호 전달 촉진합니다 The EMBO Journal. Oct, 2004 | Pubmed ID: 15385967 결합 조직 성장 인자 표현과 Smad 신호 마우스 중 개발 및 심근 경색 심장 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Nov, 2004 | Pubmed ID: 15376321 Smad1 및 생체 조건 Smad5 Spatio 시간적 활성화: Smad 단백질의 Transcriptional 활동을 모니터링 합니다 Journal of Cell Science. Sep, 2004 | Pubmed ID: 15331632 RLP, 소설 같은 Ras 단백질은 성장 인자-베타 (TGF-베타) 즉시 초기 변형 대상 유전자 부정적인 TGF-베타에 의해 유도 된 Transcriptional 활동을 규제 The Biochemical Journal. Oct, 2004 | Pubmed ID: 15239668 TGF-베타-Smad 신호에 대 한 새로운 통찰력 Trends in Biochemical Sciences. May, 2004 | Pubmed ID: 15130563 Sclerostin 뼈 형성 하지만 클래식 BMP 적의 Osteocyte 표현 부정적인 조정기는 이다 The Journal of Experimental Medicine. Mar, 2004 | Pubmed ID: 15024046 신경 성장 인자 중재 PC12 세포에서 Smad 통로의 활성화 European Journal of Biochemistry / FEBS. Mar, 2004 | Pubmed ID: 15009204 뼈 전체적 단백질 수용 체에 의해 세포 운명을 제어 합니다 Molecular and Cellular Endocrinology. Dec, 2003 | Pubmed ID: 14656483 Activin 수용 체와 같은 키 니 아 제 (ALK) 1 측면 TGFbeta/ALK5 시그널링의 대립 중재자 이다 Molecular Cell. Oct, 2003 | Pubmed ID: 14580334 중간 엽 줄기 세포 분화 TGFBeta 가족 구성원에 의해 제어 Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association. 2003 | Pubmed ID: 14557946 Osteoblast 분화에 뼈 전체적 단백질의 신호 전달 The Journal of Bone and Joint Surgery. American Volume. 2003 | Pubmed ID: 12925607 뼈 전체적 단백질의 유전자 배열을 분석 나 수용 체 유도 Osteoblast 차별화를 입력 합니다 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jul, 2003 | Pubmed ID: 12854827 Smad7 간장 주문과 셀과 쥐에서 간 섬유 증의 활성화가 되지 않습니다 Gastroenterology. Jul, 2003 | Pubmed ID: 12851882 핵 요소 YY1 변형 성장 인자 베타 및 뼈 전체적 단백질을 이용한 세포 분화를 억제 한다 Molecular and Cellular Biology. Jul, 2003 | Pubmed ID: 12808092 Phosphorylated Smad2의 마우스 개발에 TGF Beta Ligands의 대상 조직을 식별합니다 Gene Expression Patterns : GEP. Jun, 2003 | Pubmed ID: 12799085 Dsmurf는 선택적으로 매드 Decapentaplegic 활성 저하와 자사의 Overexpression Imaginal 디스크 개발을 방해 The Journal of Biological Chemistry. Jul, 2003 | Pubmed ID: 12754252 Smad 단백질과 TGF-베타 신호에 혈관 부드러운 근육 세포 International Journal of Molecular Medicine. May, 2003 | Pubmed ID: 12684705 합성 Triterpenoids 변형 성장 인자 베타/Smad 신호 강화 Cancer Research. Mar, 2003 | Pubmed ID: 12649201 변형 성장 인자-beta1 (TGF-베타)-전립선 암 세포의 유발된 Apoptosis P38의 Smad7 종속 활성화 TGF-베타 활성 키 니 아 제 1과 물질 활성화 한 단백질 키 니 아 제 키 니 아 제 3 포함 합니다 Molecular Biology of the Cell. Feb, 2003 | Pubmed ID: 12589052 성장 차별화 요소-9 Smad2 활성화 및 Inhibin B 교양된 인간 Granulosa Luteal 셀 생산을 유도합니다 The Journal of Clinical Endocrinology and Metabolism. Feb, 2003 | Pubmed ID: 12574210 변형 성장 인자-베타 1 변이 Camurati 엥 겔만 질병 이어질 활성화 또는 돌연변이 단백질의 분 비를 변경 하 여 신호 증가 The Journal of Biological Chemistry. Feb, 2003 | Pubmed ID: 12493741 변형 성장 인자-베타 Smad 요구의 나 수용 체 유도 응답을 입력 합니다 The Journal of Biological Chemistry. Feb, 2003 | Pubmed ID: 12446693 BMP 경로 Otic 캡슐 형성에 관여 하 고 상피-엽 개발 치킨 내가 있는 신호 Developmental Biology. Nov, 2002 | Pubmed ID: 12435365 뼈 전체적 단백질에 의해 Id1 식의 자극은 충분 한 내 피 세포의 뼈 전체적 단백질을 이용한 활성화에 필요한 Circulation. Oct, 2002 | Pubmed ID: 12390958 (OP-1) Osteogenetic 단백질과 토끼 관절 연골에는 수용 체의 Immunohistochemical 지역화 The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Oct, 2002 | Pubmed ID: 12364567 Activin 및 뼈 전체적 단백질 신호 통로 Smad 단백질 Inhibin B 생산 난소 Granulosa 세포에서의 유도에 참여 Molecular and Cellular Endocrinology. Sep, 2002 | Pubmed ID: 12354674 뼈 전체적 단백질/Smad 기도 염증을 하는 동안 기관지 상피 세포에서 신호를 활성화 합니다 American Journal of Respiratory Cell and Molecular Biology. Aug, 2002 | Pubmed ID: 12151307 Overexpression Smad7의 심한 병 적인 변경 여러 상피 조직에서에서 발생합니다 The EMBO Journal. Jun, 2002 | Pubmed ID: 12032071 변형 성장 인자 베타 신호 변환입니다 Journal of Leukocyte Biology. May, 2002 | Pubmed ID: 11994497 TGF-베타 수용 체 타입 두 가지를 통해 피 내 막의 활성화 상태를 균형 조정 The EMBO Journal. Apr, 2002 | Pubmed ID: 11927558 Smad 단백질에 의해 세포 증식의 규제입니다 Journal of Cellular Physiology. Apr, 2002 | Pubmed ID: 11920677 결핍 Smad7 식: Scleroderma 상 분자 결함 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002 | Pubmed ID: 11904440 작업 범위 BMP의 N 단자 기본 아미노산 핵심으로 정의 됩니다 Current Biology : CB. Feb, 2002 | Pubmed ID: 11839272 GATA 3와 Smad3는 신체적, 기능적 상호작용 GATA 대상 유전자의 TGF-베타 규제를 수 있습니다 Current Biology : CB. Jan, 2002 | Pubmed ID: 11790301 Autocrine TGF-베타 시그널링의 일시적인 중단으로 향상 된 생존 및 단일 원시 인간 Hemopoietic 조상 세포에서 잠재적인 확산 이어집니다 Journal of Immunology (Baltimore, Md. : 1950). Jan, 2002 | Pubmed ID: 11777969 신분증과 Id1 발기인에 뚜렷한 비판적으로 중요 한 뼈 전체적 단백질 관련 응답 요소의 기능적 특성 The Journal of Biological Chemistry. Feb, 2002 | Pubmed ID: 11729207 Deubiquitinase Activity Profiling Identifies UCHL1 As a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. | Pubmed ID: 31857432 TGF-β 매개 내피- 중간엽 전환(EndMT)과 CRISPR/Cas9 유전자 편집을 사용하여 EndMT 이펙터의 기능평가 Jin Ma1,2, Gerard van der Zon1,2, Gonzalo Sanchez-Duffhues1, Peter ten Dijke1,2 1Dept. Cell Chemical Biology, Leiden University Medical Center, 2Oncode Institute, Leiden University Medical Center JoVE 62198 Biologia 유방암과 정상 세포에서 TGF β 신호 및 TGF β 유도 된 상피 - 중간 엽 전환 연구 Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 Ricerca sul cancro 배아 Zebrafish의 인간 유방암 세포의 침략 행동 Jiang Ren*1, Sijia Liu*1, Chao Cui1, Peter ten Dijke1 1Department of Molecular Cell Biology, Cancer Genomics Centre Netherlands, Leiden University Medical Center JoVE 55459 Ricerca sul cancro TGF - β - 유발 침략을 측정하는 회전 타원체 분석 Hildegonda P.H. Naber1, Eliza Wiercinska1, Peter ten Dijke1, Theo van Laar1 1Department of Molecular Cell Biology and Centre for Biomedial Genetics, Leiden University Medical Centre JoVE 3337 Medicina
TGF-β 매개 내피- 중간엽 전환(EndMT)과 CRISPR/Cas9 유전자 편집을 사용하여 EndMT 이펙터의 기능평가 Jin Ma1,2, Gerard van der Zon1,2, Gonzalo Sanchez-Duffhues1, Peter ten Dijke1,2 1Dept. Cell Chemical Biology, Leiden University Medical Center, 2Oncode Institute, Leiden University Medical Center JoVE 62198 Biologia
유방암과 정상 세포에서 TGF β 신호 및 TGF β 유도 된 상피 - 중간 엽 전환 연구 Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 Ricerca sul cancro
배아 Zebrafish의 인간 유방암 세포의 침략 행동 Jiang Ren*1, Sijia Liu*1, Chao Cui1, Peter ten Dijke1 1Department of Molecular Cell Biology, Cancer Genomics Centre Netherlands, Leiden University Medical Center JoVE 55459 Ricerca sul cancro
TGF - β - 유발 침략을 측정하는 회전 타원체 분석 Hildegonda P.H. Naber1, Eliza Wiercinska1, Peter ten Dijke1, Theo van Laar1 1Department of Molecular Cell Biology and Centre for Biomedial Genetics, Leiden University Medical Centre JoVE 3337 Medicina