Robert J. Levy The Children's Hospital of Philadelphia Biography Publications Institution JoVE Articles Robert J. Levy has not added a biography. If you are Robert J. Levy and would like to personalize this page please email our Author Liaison for assistance. Publications Experimental Single-Platform Approach to Enhance the Functionalization of Magnetically Targetable Cells ACS Applied Bio Materials. Jun, 2020 | Pubmed ID: 33251488 Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves JACC. Basic to Translational Science. Aug, 2020 | Pubmed ID: 32875167 Circulating and Tissue Matricellular RNA and Protein Expression in Calcific Aortic Valve Disease Physiological Genomics. 04, 2020 | Pubmed ID: 32089075 Comparative Pathology of Human and Canine Myxomatous Mitral Valve Degeneration: 5HT and TGF-β Mechanisms Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. May - Jun, 2020 | Pubmed ID: 32006823 Stability and Bioactivity of PepCD47 Attachment on Stainless Steel Surfaces Acta Biomaterialia. 03, 2020 | Pubmed ID: 31935523 Cardiovascular Delivery of Drugs and Biotherapeutics Drug Delivery and Translational Research. Aug, 2018 | Pubmed ID: 29359245 Serotonin Receptor 2B Signaling with Interstitial Cell Activation and Leaflet Remodeling in Degenerative Mitral Regurgitation Journal of Molecular and Cellular Cardiology. 02, 2018 | Pubmed ID: 29291394 Optimizing Endothelial Cell Functionalization for Cell Therapy of Vascular Proliferative Disease Using a Direct Contact Co-culture System Drug Delivery and Translational Research. 08, 2018 | Pubmed ID: 28755158 Serotonin and Catecholamines in the Development and Progression of Heart Valve Diseases Cardiovascular Research. Jul, 2017 | Pubmed ID: 28863437 Calcification and Oxidative Modifications Are Associated With Progressive Bioprosthetic Heart Valve Dysfunction Journal of the American Heart Association. May, 2017 | Pubmed ID: 28483776 Paraffin Processing of Stented Arteries Using a Postfixation Dissolution of Metallic and Polymeric Stents Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Nov - Dec, 2016 | Pubmed ID: 27616613 The Use of CD47-modified Biomaterials to Mitigate the Immune Response Experimental Biology and Medicine (Maywood, N.J.). 05, 2016 | Pubmed ID: 27190273 Enhanced Biocompatibility of CD47-functionalized Vascular Stents Biomaterials. May, 2016 | Pubmed ID: 26914699 Magnetically Enhanced Cell Delivery for Accelerating Recovery of the Endothelium in Injured Arteries Journal of Controlled Release : Official Journal of the Controlled Release Society. Jan, 2016 | Pubmed ID: 26704936 Nanoparticle-mediated Delivery of a Rapidly Activatable Prodrug of SN-38 for Neuroblastoma Therapy Biomaterials. May, 2015 | Pubmed ID: 25770994 Nanoparticle Delivery of an SN38 Conjugate is More Effective Than Irinotecan in a Mouse Model of Neuroblastoma Cancer Letters. May, 2015 | Pubmed ID: 25684664 The Effects of the Covalent Attachment of 3-(4-hydroxy-3,5-di-tert-butylphenyl) Propyl Amine to Glutaraldehyde Pretreated Bovine Pericardium on Structural Degeneration, Oxidative Modification, and Calcification of Rat Subdermal Implants Journal of Biomedical Materials Research. Part A. Jul, 2015 | Pubmed ID: 25546235 Real-time Analysis of Composite Magnetic Nanoparticle Disassembly in Vascular Cells and Biomimetic Media Proceedings of the National Academy of Sciences of the United States of America. Mar, 2014 | Pubmed ID: 24591603 Endothelial Targeting of Nanocarriers Loaded with Antioxidant Enzymes for Protection Against Vascular Oxidative Stress and Inflammation Biomaterials. Apr, 2014 | Pubmed ID: 24480537 The Susceptibility of Bioprosthetic Heart Valve Leaflets to Oxidation Biomaterials. Feb, 2014 | Pubmed ID: 24360721 Endovascular Gene Delivery from a Stent Platform: Gene- Eluting Stents Angiology: Open Access. 2013 | Pubmed ID: 26225356 Modulation of NO and ROS Production by AdiNOS Transduced Vascular Cells Through Supplementation with L-Arg and BH4: Implications for Gene Therapy of Restenosis Atherosclerosis. Sep, 2013 | Pubmed ID: 23958248 Intracellular Signaling Mechanisms Associated with CD47 Modified Surfaces Biomaterials. Nov, 2013 | Pubmed ID: 23948164 Adenoviral Vector Tethering to Metal Surfaces Via Hydrolyzable Cross-linkers for the Modulation of Vector Release and Transduction Biomaterials. Sep, 2013 | Pubmed ID: 23777912 Site-specific Gene Delivery to Stented Arteries Using Magnetically Guided Zinc Oleate-based Nanoparticles Loaded with Adenoviral Vectors FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2013 | Pubmed ID: 23407712 Antioxidant Enzymes Reduce DNA Damage and Early Activation of Valvular Interstitial Cells in Aortic Valve Sclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2013 | Pubmed ID: 23241403 Blood Flow Reprograms Lymphatic Vessels to Blood Vessels The Journal of Clinical Investigation. Jun, 2012 | Pubmed ID: 22622036 Diminished Adhesion and Activation of Platelets and Neutrophils with CD47 Functionalized Blood Contacting Surfaces Biomaterials. Aug, 2012 | Pubmed ID: 22613135 Formulation and in Vitro Characterization of Composite Biodegradable Magnetic Nanoparticles for Magnetically Guided Cell Delivery Pharmaceutical Research. May, 2012 | Pubmed ID: 22274555 Triglycidyl Amine Crosslinking Combined with Ethanol Inhibits Bioprosthetic Heart Valve Calcification The Annals of Thoracic Surgery. Sep, 2011 | Pubmed ID: 21871270 Aortic Valve Cyclic Stretch Causes Increased Remodeling Activity and Enhanced Serotonin Receptor Responsiveness The Annals of Thoracic Surgery. Jul, 2011 | Pubmed ID: 21718840 The Effect of CD47 Modified Polymer Surfaces on Inflammatory Cell Attachment and Activation Biomaterials. Jul, 2011 | Pubmed ID: 21429575 CD47-dependent Molecular Mechanisms of Blood Outgrowth Endothelial Cell Attachment on Cholesterol-modified Polyurethane Biomaterials. Sep, 2010 | Pubmed ID: 20538335 Endothelial Delivery of Antioxidant Enzymes Loaded into Non-polymeric Magnetic Nanoparticles Journal of Controlled Release : Official Journal of the Controlled Release Society. Aug, 2010 | Pubmed ID: 20483366 Targeting Stents with Local Delivery of Paclitaxel-loaded Magnetic Nanoparticles Using Uniform Fields Proceedings of the National Academy of Sciences of the United States of America. May, 2010 | Pubmed ID: 20404175 Prevention of Polyurethane Oxidative Degradation with Phenolic Antioxidants Covalently Attached to the Hard Segments: Structure-function Relationships Journal of Biomedical Materials Research. Part A. Sep, 2010 | Pubmed ID: 20306526 Site-specific Gene Therapy for Cardiovascular Disease Current Opinion in Drug Discovery & Development. Mar, 2010 | Pubmed ID: 20205054 Fenfluramine Disrupts the Mitral Valve Interstitial Cell Response to Serotonin The American Journal of Pathology. Sep, 2009 | Pubmed ID: 19679875 Magnetically Responsive Biodegradable Nanoparticles Enhance Adenoviral Gene Transfer in Cultured Smooth Muscle and Endothelial Cells Molecular Pharmaceutics. Sep-Oct, 2009 | Pubmed ID: 19496618 Site-specific Analgesia with Sustained Release Liposomes Proceedings of the National Academy of Sciences of the United States of America. Apr, 2009 | Pubmed ID: 19416926 Local Delivery of Gene Vectors from Bare-metal Stents by Use of a Biodegradable Synthetic Complex Inhibits In-stent Restenosis in Rat Carotid Arteries Circulation. Apr, 2008 | Pubmed ID: 18413497 Magnetically Driven Plasmid DNA Delivery with Biodegradable Polymeric Nanoparticles FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2007 | Pubmed ID: 17403937 Biological Stability of Polyurethane Modified with Covalent Attachment of Di-tert-butyl-phenol Journal of Biomedical Materials Research. Part A. Sep, 2007 | Pubmed ID: 17370325 Transforming Growth Factor-beta1 Mechanisms in Aortic Valve Calcification: Increased Alkaline Phosphatase and Related Events The Annals of Thoracic Surgery. Mar, 2007 | Pubmed ID: 17307438 Adenoviral Gene Vector Tethering to Nanoparticle Surfaces Results in Receptor-independent Cell Entry and Increased Transgene Expression Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2006 | Pubmed ID: 16807119 Prevention of Oxidative Degradation of Polyurethane by Covalent Attachment of Di-tert-butylphenol Residues Journal of Biomedical Materials Research. Part A. Sep, 2006 | Pubmed ID: 16736485 Bisphosphonate-mediated Gene Vector Delivery from the Metal Surfaces of Stents Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16371477 Cholesterol-modified Polyurethane Valve Cusps Demonstrate Blood Outgrowth Endothelial Cell Adhesion Post-seeding in Vitro and in Vivo The Annals of Thoracic Surgery. Jan, 2006 | Pubmed ID: 16368333 Prevention of Calcification of Bioprosthetic Heart Valve Cusp and Aortic Wall with Ethanol and Aluminum Chloride The Annals of Thoracic Surgery. Mar, 2005 | Pubmed ID: 15734402 Triglycidylamine Crosslinking of Porcine Aortic Valve Cusps or Bovine Pericardium Results in Improved Biocompatibility, Biomechanics, and Calcification Resistance: Chemical and Biological Mechanisms The American Journal of Pathology. Jan, 2005 | Pubmed ID: 15631995 Cholesterol-derivatized Polyurethane: Characterization and Endothelial Cell Adhesion Journal of Biomedical Materials Research. Part A. Feb, 2005 | Pubmed ID: 15625684 Prevention of Polyurethane Valve Cusp Calcification with Covalently Attached Bisphosphonate Diethylamino Moieties Journal of Biomedical Materials Research. Part A. Aug, 2003 | Pubmed ID: 12889009 Thymosin Beta4 Regulation, Expression and Function in Aortic Valve Interstitial Cells The Journal of Heart Valve Disease. Sep, 2002 | Pubmed ID: 12358412 Elastin Calcification and Its Prevention with Aluminum Chloride Pretreatment The American Journal of Pathology. Sep, 1999 | Pubmed ID: 10487855 Arterial Uptake of Biodegradable Nanoparticles for Intravascular Local Drug Delivery: Results with an Acute Dog Model Journal of Controlled Release : Official Journal of the Controlled Release Society. Jul, 1998 | Pubmed ID: 9724907 Mitigatie van Blood Borne Cell Attachment to Metal Implants through CD47-Derived Peptide Immobilisatie Vaishali V. Inamdar1, Emmett G. Fitzpatrick1, Ivan S. Alferiev1,2, Robert J. Levy1,2, Stanley J. Stachelek*1,2, Ilia Fishbein*1,2 1The Children's Hospital of Philadelphia, 2Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania JoVE 61545 Bioingegneria
Mitigatie van Blood Borne Cell Attachment to Metal Implants through CD47-Derived Peptide Immobilisatie Vaishali V. Inamdar1, Emmett G. Fitzpatrick1, Ivan S. Alferiev1,2, Robert J. Levy1,2, Stanley J. Stachelek*1,2, Ilia Fishbein*1,2 1The Children's Hospital of Philadelphia, 2Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania JoVE 61545 Bioingegneria