Robert J. Levy The Children's Hospital of Philadelphia Biography Publications Institution JoVE Articles Robert J. Levy has not added a biography. If you are Robert J. Levy and would like to personalize this page please email our Author Liaison for assistance. Publications Experimental Single-Platform Approach to Enhance the Functionalization of Magnetically Targetable Cells ACS Applied Bio Materials. Jun, 2020 | Pubmed ID: 33251488 Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves JACC. Basic to Translational Science. Aug, 2020 | Pubmed ID: 32875167 Circulating and Tissue Matricellular RNA and Protein Expression in Calcific Aortic Valve Disease Physiological Genomics. 04, 2020 | Pubmed ID: 32089075 Comparative Pathology of Human and Canine Myxomatous Mitral Valve Degeneration: 5HT and TGF-β Mechanisms Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. May - Jun, 2020 | Pubmed ID: 32006823 Stability and Bioactivity of PepCD47 Attachment on Stainless Steel Surfaces Acta Biomaterialia. 03, 2020 | Pubmed ID: 31935523 Cardiovascular Delivery of Drugs and Biotherapeutics Drug Delivery and Translational Research. Aug, 2018 | Pubmed ID: 29359245 Serotonin Receptor 2B Signaling with Interstitial Cell Activation and Leaflet Remodeling in Degenerative Mitral Regurgitation Journal of Molecular and Cellular Cardiology. 02, 2018 | Pubmed ID: 29291394 Optimizing Endothelial Cell Functionalization for Cell Therapy of Vascular Proliferative Disease Using a Direct Contact Co-culture System Drug Delivery and Translational Research. 08, 2018 | Pubmed ID: 28755158 Serotonin and Catecholamines in the Development and Progression of Heart Valve Diseases Cardiovascular Research. Jul, 2017 | Pubmed ID: 28863437 Calcification and Oxidative Modifications Are Associated With Progressive Bioprosthetic Heart Valve Dysfunction Journal of the American Heart Association. May, 2017 | Pubmed ID: 28483776 Paraffin Processing of Stented Arteries Using a Postfixation Dissolution of Metallic and Polymeric Stents Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Nov - Dec, 2016 | Pubmed ID: 27616613 The Use of CD47-modified Biomaterials to Mitigate the Immune Response Experimental Biology and Medicine (Maywood, N.J.). 05, 2016 | Pubmed ID: 27190273 Enhanced Biocompatibility of CD47-functionalized Vascular Stents Biomaterials. May, 2016 | Pubmed ID: 26914699 Magnetically Enhanced Cell Delivery for Accelerating Recovery of the Endothelium in Injured Arteries Journal of Controlled Release : Official Journal of the Controlled Release Society. Jan, 2016 | Pubmed ID: 26704936 Nanoparticle-mediated Delivery of a Rapidly Activatable Prodrug of SN-38 for Neuroblastoma Therapy Biomaterials. May, 2015 | Pubmed ID: 25770994 Nanoparticle Delivery of an SN38 Conjugate is More Effective Than Irinotecan in a Mouse Model of Neuroblastoma Cancer Letters. May, 2015 | Pubmed ID: 25684664 The Effects of the Covalent Attachment of 3-(4-hydroxy-3,5-di-tert-butylphenyl) Propyl Amine to Glutaraldehyde Pretreated Bovine Pericardium on Structural Degeneration, Oxidative Modification, and Calcification of Rat Subdermal Implants Journal of Biomedical Materials Research. Part A. Jul, 2015 | Pubmed ID: 25546235 Real-time Analysis of Composite Magnetic Nanoparticle Disassembly in Vascular Cells and Biomimetic Media Proceedings of the National Academy of Sciences of the United States of America. Mar, 2014 | Pubmed ID: 24591603 Endothelial Targeting of Nanocarriers Loaded with Antioxidant Enzymes for Protection Against Vascular Oxidative Stress and Inflammation Biomaterials. Apr, 2014 | Pubmed ID: 24480537 The Susceptibility of Bioprosthetic Heart Valve Leaflets to Oxidation Biomaterials. Feb, 2014 | Pubmed ID: 24360721 Endovascular Gene Delivery from a Stent Platform: Gene- Eluting Stents Angiology: Open Access. 2013 | Pubmed ID: 26225356 Modulation of NO and ROS Production by AdiNOS Transduced Vascular Cells Through Supplementation with L-Arg and BH4: Implications for Gene Therapy of Restenosis Atherosclerosis. Sep, 2013 | Pubmed ID: 23958248 Intracellular Signaling Mechanisms Associated with CD47 Modified Surfaces Biomaterials. Nov, 2013 | Pubmed ID: 23948164 Adenoviral Vector Tethering to Metal Surfaces Via Hydrolyzable Cross-linkers for the Modulation of Vector Release and Transduction Biomaterials. Sep, 2013 | Pubmed ID: 23777912 Site-specific Gene Delivery to Stented Arteries Using Magnetically Guided Zinc Oleate-based Nanoparticles Loaded with Adenoviral Vectors FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2013 | Pubmed ID: 23407712 Antioxidant Enzymes Reduce DNA Damage and Early Activation of Valvular Interstitial Cells in Aortic Valve Sclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2013 | Pubmed ID: 23241403 Blood Flow Reprograms Lymphatic Vessels to Blood Vessels The Journal of Clinical Investigation. Jun, 2012 | Pubmed ID: 22622036 Diminished Adhesion and Activation of Platelets and Neutrophils with CD47 Functionalized Blood Contacting Surfaces Biomaterials. Aug, 2012 | Pubmed ID: 22613135 Formulation and in Vitro Characterization of Composite Biodegradable Magnetic Nanoparticles for Magnetically Guided Cell Delivery Pharmaceutical Research. May, 2012 | Pubmed ID: 22274555 Triglycidyl Amine Crosslinking Combined with Ethanol Inhibits Bioprosthetic Heart Valve Calcification The Annals of Thoracic Surgery. Sep, 2011 | Pubmed ID: 21871270 Aortic Valve Cyclic Stretch Causes Increased Remodeling Activity and Enhanced Serotonin Receptor Responsiveness The Annals of Thoracic Surgery. Jul, 2011 | Pubmed ID: 21718840 The Effect of CD47 Modified Polymer Surfaces on Inflammatory Cell Attachment and Activation Biomaterials. Jul, 2011 | Pubmed ID: 21429575 CD47-dependent Molecular Mechanisms of Blood Outgrowth Endothelial Cell Attachment on Cholesterol-modified Polyurethane Biomaterials. Sep, 2010 | Pubmed ID: 20538335 Endothelial Delivery of Antioxidant Enzymes Loaded into Non-polymeric Magnetic Nanoparticles Journal of Controlled Release : Official Journal of the Controlled Release Society. Aug, 2010 | Pubmed ID: 20483366 Orientación De Los Stents Con Liberación Local De Paclitaxel Nanopartículas Magnéticas Cargadas De Uso De Los Campos Uniformes Proceedings of the National Academy of Sciences of the United States of America. May, 2010 | Pubmed ID: 20404175 Prevention of Polyurethane Oxidative Degradation with Phenolic Antioxidants Covalently Attached to the Hard Segments: Structure-function Relationships Journal of Biomedical Materials Research. Part A. Sep, 2010 | Pubmed ID: 20306526 Site-specific Gene Therapy for Cardiovascular Disease Current Opinion in Drug Discovery & Development. Mar, 2010 | Pubmed ID: 20205054 Fenfluramine Disrupts the Mitral Valve Interstitial Cell Response to Serotonin The American Journal of Pathology. Sep, 2009 | Pubmed ID: 19679875 Magnetically Responsive Biodegradable Nanoparticles Enhance Adenoviral Gene Transfer in Cultured Smooth Muscle and Endothelial Cells Molecular Pharmaceutics. Sep-Oct, 2009 | Pubmed ID: 19496618 Site-specific Analgesia with Sustained Release Liposomes Proceedings of the National Academy of Sciences of the United States of America. Apr, 2009 | Pubmed ID: 19416926 Local Delivery of Gene Vectors from Bare-metal Stents by Use of a Biodegradable Synthetic Complex Inhibits In-stent Restenosis in Rat Carotid Arteries Circulation. Apr, 2008 | Pubmed ID: 18413497 Magnetically Driven Plasmid DNA Delivery with Biodegradable Polymeric Nanoparticles FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2007 | Pubmed ID: 17403937 Biological Stability of Polyurethane Modified with Covalent Attachment of Di-tert-butyl-phenol Journal of Biomedical Materials Research. Part A. Sep, 2007 | Pubmed ID: 17370325 Transforming Growth Factor-beta1 Mechanisms in Aortic Valve Calcification: Increased Alkaline Phosphatase and Related Events The Annals of Thoracic Surgery. Mar, 2007 | Pubmed ID: 17307438 Adenoviral Gene Vector Tethering to Nanoparticle Surfaces Results in Receptor-independent Cell Entry and Increased Transgene Expression Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2006 | Pubmed ID: 16807119 Prevention of Oxidative Degradation of Polyurethane by Covalent Attachment of Di-tert-butylphenol Residues Journal of Biomedical Materials Research. Part A. Sep, 2006 | Pubmed ID: 16736485 Bisphosphonate-mediated Gene Vector Delivery from the Metal Surfaces of Stents Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16371477 Cholesterol-modified Polyurethane Valve Cusps Demonstrate Blood Outgrowth Endothelial Cell Adhesion Post-seeding in Vitro and in Vivo The Annals of Thoracic Surgery. Jan, 2006 | Pubmed ID: 16368333 Prevention of Calcification of Bioprosthetic Heart Valve Cusp and Aortic Wall with Ethanol and Aluminum Chloride The Annals of Thoracic Surgery. Mar, 2005 | Pubmed ID: 15734402 Triglycidylamine Crosslinking of Porcine Aortic Valve Cusps or Bovine Pericardium Results in Improved Biocompatibility, Biomechanics, and Calcification Resistance: Chemical and Biological Mechanisms The American Journal of Pathology. Jan, 2005 | Pubmed ID: 15631995 Cholesterol-derivatized Polyurethane: Characterization and Endothelial Cell Adhesion Journal of Biomedical Materials Research. Part A. Feb, 2005 | Pubmed ID: 15625684 Prevention of Polyurethane Valve Cusp Calcification with Covalently Attached Bisphosphonate Diethylamino Moieties Journal of Biomedical Materials Research. Part A. Aug, 2003 | Pubmed ID: 12889009 Thymosin Beta4 Regulation, Expression and Function in Aortic Valve Interstitial Cells The Journal of Heart Valve Disease. Sep, 2002 | Pubmed ID: 12358412 Elastin Calcification and Its Prevention with Aluminum Chloride Pretreatment The American Journal of Pathology. Sep, 1999 | Pubmed ID: 10487855 Arterial Uptake of Biodegradable Nanoparticles for Intravascular Local Drug Delivery: Results with an Acute Dog Model Journal of Controlled Release : Official Journal of the Controlled Release Society. Jul, 1998 | Pubmed ID: 9724907 Mitigación de la fijación de células de flujo sanguíneo a implantes metálicos a través de la inmovilización de péptidos derivados de CD47 Vaishali V. Inamdar1, Emmett G. Fitzpatrick1, Ivan S. Alferiev1,2, Robert J. Levy1,2, Stanley J. Stachelek*1,2, Ilia Fishbein*1,2 1The Children's Hospital of Philadelphia, 2Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania JoVE 61545 Bioingegneria
Mitigación de la fijación de células de flujo sanguíneo a implantes metálicos a través de la inmovilización de péptidos derivados de CD47 Vaishali V. Inamdar1, Emmett G. Fitzpatrick1, Ivan S. Alferiev1,2, Robert J. Levy1,2, Stanley J. Stachelek*1,2, Ilia Fishbein*1,2 1The Children's Hospital of Philadelphia, 2Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania JoVE 61545 Bioingegneria