Roberto Weigert Biography Publications JoVE Articles Roberto Weigert has not added a biography. If you are Roberto Weigert and would like to personalize this page please email our Author Liaison for assistance. Publications The Butyrophilin 1a1 Knockout Mouse Revisited: Ablation of Leads to Concurrent Cell Death and Renewal in the Mammary Epithelium During Lactation FASEB BioAdvances. Dec, 2021 | Pubmed ID: 34938960 Method for Acute Intravital Imaging of the Large Intestine in Live Mice Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 34028723 Calcineurin Inhibitors Suppress Acute Graft-versus-host Disease Via NFAT-independent Inhibition of T Cell Receptor Signaling The Journal of Clinical Investigation. 06, 2021 | Pubmed ID: 33822776 Transduction of Salivary Gland Acinar Cells with a Novel AAV Vector 44.9 Molecular Therapy. Methods & Clinical Development. Dec, 2020 | Pubmed ID: 33294494 Collective Cancer Cell Invasion Requires RNA Accumulation at the Invasive Front Proceedings of the National Academy of Sciences of the United States of America. 11, 2020 | Pubmed ID: 33060293 The LTB4-BLT1 Axis Regulates Actomyosin and β2-integrin Dynamics During Neutrophil Extravasation The Journal of Cell Biology. 10, 2020 | Pubmed ID: 32854115 A Role for Keratins in Supporting Mitochondrial Organization and Function in Skin Keratinocytes Molecular Biology of the Cell. 05, 2020 | Pubmed ID: 32213122 Cdc42 Controls Secretory Granules Morphology in Rodent Salivary Glands in Vivo Communicative & Integrative Biology. 2020 | Pubmed ID: 32128025 Nanoarchitecture and Dynamics of the Mouse Enteric Glycocalyx Examined by Freeze-etching Electron Tomography and Intravital Microscopy Communications Biology. 01, 2020 | Pubmed ID: 31925335 Dynamic Polyhedral Actomyosin Lattices Remodel Micron-scale Curved Membranes During Exocytosis in Live Mice Nature Cell Biology. 08, 2019 | Pubmed ID: 31358965 Intravital Microscopy in Mammalian Multicellular Organisms Current Opinion in Cell Biology. 08, 2019 | Pubmed ID: 31125832 Pak1 Kinase Promotes Activated T Cell Trafficking by Regulating the Expression of L-Selectin and CCR7 Frontiers in Immunology. 2019 | Pubmed ID: 30891040 Mitochondrial Populations Exhibit Differential Dynamic Responses to Increased Energy Demand During Exocytosis In Vivo IScience. Jan, 2019 | Pubmed ID: 30661001 Cdc42 Negatively Regulates Endocytosis During Apical Membrane Maintenance in Live Animals Molecular Biology of the Cell. 02, 2019 | Pubmed ID: 30540520 Symposium Review: Intravital Imaging of the Lactating Mammary Gland in Live Mice Reveals Novel Aspects of Milk-lipid Secretion Journal of Dairy Science. Mar, 2019 | Pubmed ID: 30471915 The Actomyosin Cytoskeleton Drives Micron-Scale Membrane Remodeling In Vivo Via the Generation of Mechanical Forces to Balance Membrane Tension Gradients BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. 09, 2018 | Pubmed ID: 30080263 ONC201 Kills Breast Cancer Cells by Targeting Mitochondria Oncotarget. Apr, 2018 | Pubmed ID: 29719618 Parallel Assembly of Actin and Tropomyosin, but Not Myosin II, During Actin Filament Formation in Live Mice Journal of Cell Science. 03, 2018 | Pubmed ID: 29487177 Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen Through Cellular Uptake Cell Reports. 12, 2017 | Pubmed ID: 29281816 Isoform-specific Roles of NMII Drive Membrane Remodeling in Vivo Cell Cycle (Georgetown, Tex.). 10, 2017 | Pubmed ID: 28937881 ER/Golgi Trafficking is Facilitated by Unbranched Actin Filaments Containing Tpm4.2 Cytoskeleton (Hoboken, N.J.). Oct, 2017 | Pubmed ID: 28834398 Non-invasive Intravital Imaging of Head and Neck Squamous Cell Carcinomas in Live Mice Methods (San Diego, Calif.). 09, 2017 | Pubmed ID: 28780320 Concerted Actions of Distinct Nonmuscle Myosin II Isoforms Drive Intracellular Membrane Remodeling in Live Animals The Journal of Cell Biology. 07, 2017 | Pubmed ID: 28600434 A Predictive 3D Multi-Scale Model of Biliary Fluid Dynamics in the Liver Lobule Cell Systems. 03, 2017 | Pubmed ID: 28330614 Kinetics of Milk Lipid Droplet Transport, Growth, and Secretion Revealed by Intravital Imaging: Lipid Droplet Release is Intermittently Stimulated by Oxytocin Molecular Biology of the Cell. Apr, 2017 | Pubmed ID: 28179456 Toward In vivo Two-photon Analysis of Mouse Aqueous Outflow Structure and Function Experimental Eye Research. 05, 2017 | Pubmed ID: 27179411 Sinusoidal Ephrin Receptor EPHB4 Controls Hematopoietic Progenitor Cell Mobilization from Bone Marrow The Journal of Clinical Investigation. 12, 2016 | Pubmed ID: 27820703 Direct Regulation of Alternative Splicing by SMAD3 Through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β Molecular Cell. Nov, 2016 | Pubmed ID: 27746021 Liver Kinase B1 Regulates Hepatocellular Tight Junction Distribution and Function in Vivo Hepatology (Baltimore, Md.). 10, 2016 | Pubmed ID: 27396550 A CCR2 Macrophage Endocytic Pathway Mediates Extravascular Fibrin Clearance in Vivo Blood. Mar, 2016 | Pubmed ID: 26647393 Arp2/3-mediated F-actin Formation Controls Regulated Exocytosis in Vivo Nature Communications. Dec, 2015 | Pubmed ID: 26639106 Imaging Membrane Remodeling During Regulated Exocytosis in Live Mice Experimental Cell Research. Oct, 2015 | Pubmed ID: 26160452 RhoA and ROCK Mediate Histamine-induced Vascular Leakage and Anaphylactic Shock Nature Communications. Apr, 2015 | Pubmed ID: 25857352 SDF-1/CXCL12 Induces Directional Cell Migration and Spontaneous Metastasis Via a CXCR4/Gαi/mTORC1 Axis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2015 | Pubmed ID: 25466898 Polyethylenimine-mediated Expression of Transgenes in the Acinar Cells of Rats Salivary Glands in Vivo Frontiers in Cell and Developmental Biology. 2014 | Pubmed ID: 25621283 In Vivo Tissue-wide Synchronization of Mitochondrial Metabolic Oscillations Cell Reports. Oct, 2014 | Pubmed ID: 25373899 Altered Endosome Biogenesis in Prostate Cancer Has Biomarker Potential Molecular Cancer Research : MCR. Dec, 2014 | Pubmed ID: 25080433 Probing the Role of the Actin Cytoskeleton During Regulated Exocytosis by Intravital Microscopy Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24947398 Two-photon Excitation Improves Multifocal Structured Illumination Microscopy in Thick Scattering Tissue Proceedings of the National Academy of Sciences of the United States of America. Apr, 2014 | Pubmed ID: 24706872 Imaging the Dynamics of Endocytosis in Live Mammalian Tissues Cold Spring Harbor Perspectives in Biology. Apr, 2014 | Pubmed ID: 24691962 Neutral Lipid Stores and Lipase PNPLA5 Contribute to Autophagosome Biogenesis Current Biology : CB. Mar, 2014 | Pubmed ID: 24613307 Endosomes Derived from Clathrin-independent Endocytosis Serve As Precursors for Endothelial Lumen Formation PloS One. 2013 | Pubmed ID: 24282620 CX3CR1-dependent Renal Macrophage Survival Promotes Candida Control and Host Survival The Journal of Clinical Investigation. Dec, 2013 | Pubmed ID: 24177428 Autophagy Regulates Endothelial Cell Processing, Maturation and Secretion of Von Willebrand Factor Nature Medicine. Oct, 2013 | Pubmed ID: 24056772 M2-like Macrophages Are Responsible for Collagen Degradation Through a Mannose Receptor-mediated Pathway The Journal of Cell Biology. Sep, 2013 | Pubmed ID: 24019537 Imaging Cell Biology in Live Animals: Ready for Prime Time The Journal of Cell Biology. Jun, 2013 | Pubmed ID: 23798727 Rab25 Regulates Invasion and Metastasis in Head and Neck Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2013 | Pubmed ID: 23340300 Intravital Microscopy to Image Membrane Trafficking in Live Rats Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23027003 Multiple Roles for the Actin Cytoskeleton During Regulated Exocytosis Cellular and Molecular Life Sciences : CMLS. Jun, 2013 | Pubmed ID: 22986507 Intravital Microscopy Reveals Differences in the Kinetics of Endocytic Pathways Between Cell Cultures and Live Animals Cells. Nov, 2012 | Pubmed ID: 24710546 Intravital Microscopy: A Practical Guide on Imaging Intracellular Structures in Live Animals Bioarchitecture. Sep, 2012 | Pubmed ID: 22992750 Melanoregulin Regulates a Shedding Mechanism That Drives Melanosome Transfer from Melanocytes to Keratinocytes Proceedings of the National Academy of Sciences of the United States of America. Jul, 2012 | Pubmed ID: 22753477 Plasmid DNA is Internalized from the Apical Plasma Membrane of the Salivary Gland Epithelium in Live Animals Histochemistry and Cell Biology. Aug, 2012 | Pubmed ID: 22544351 Linking Differences in Membrane Tension with the Requirement for a Contractile Actomyosin Scaffold During Exocytosis in Salivary Glands Communicative & Integrative Biology. Jan, 2012 | Pubmed ID: 22482019 Regulated Exocytosis: Novel Insights from Intravital Microscopy Traffic (Copenhagen, Denmark). May, 2012 | Pubmed ID: 22243493 The Cyclooxygenase-2 Pathway Via the PGEâ‚‚ EP2 Receptor Contributes to Oligodendrocytes Apoptosis in Cuprizone-induced Demyelination Journal of Neurochemistry. May, 2012 | Pubmed ID: 21699540 Homeostasis of the Apical Plasma Membrane During Regulated Exocytosis in the Salivary Glands of Live Rodents Bioarchitecture. Sep, 2011 | Pubmed ID: 22754613 Decreased Lymphangiogenesis and Lymph Node Metastasis by MTOR Inhibition in Head and Neck Cancer Cancer Research. Nov, 2011 | Pubmed ID: 21975930 A Synthetic Biology Approach Reveals a CXCR4-G13-Rho Signaling Axis Driving Transendothelial Migration of Metastatic Breast Cancer Cells Science Signaling. Sep, 2011 | Pubmed ID: 21934106 Role for the Actomyosin Complex in Regulated Exocytosis Revealed by Intravital Microscopy Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21808006 Cyclooxygenase-1 is Involved in the Inhibition of Hippocampal Neurogenesis After Lipopolysaccharide-induced Neuroinflammation Cell Cycle (Georgetown, Tex.). Aug, 2011 | Pubmed ID: 21694498 Intravital Microscopy As a Tool to Study Drug Delivery in Preclinical Studies Advanced Drug Delivery Reviews. Jan-Feb, 2011 | Pubmed ID: 20933026 Matriptase Initiates Activation of Epidermal Pro-kallikrein and Disease Onset in a Mouse Model of Netherton Syndrome Nature Genetics. Aug, 2010 | Pubmed ID: 20657595 Semaphorin 3E Initiates Antiangiogenic Signaling Through Plexin D1 by Regulating Arf6 and R-Ras Molecular and Cellular Biology. Jun, 2010 | Pubmed ID: 20385769 Intravital Microscopy: a Novel Tool to Study Cell Biology in Living Animals Histochemistry and Cell Biology. May, 2010 | Pubmed ID: 20372919 Expression of Plasmid DNA in the Salivary Gland Epithelium: Novel Approaches to Study Dynamic Cellular Processes in Live Animals American Journal of Physiology. Cell Physiology. Dec, 2009 | Pubmed ID: 19794147 Myosin Vc is a Molecular Motor That Functions in Secretory Granule Trafficking Molecular Biology of the Cell. Nov, 2009 | Pubmed ID: 19741097 The Effect of Hypusine Modification on the Intracellular Localization of EIF5A Biochemical and Biophysical Research Communications. Jun, 2009 | Pubmed ID: 19379712 Discovery of New Cargo Proteins That Enter Cells Through Clathrin-independent Endocytosis Traffic (Copenhagen, Denmark). May, 2009 | Pubmed ID: 19302270 A Role for a CXCR2/phosphatidylinositol 3-kinase Gamma Signaling Axis in Acute and Chronic Vascular Permeability Molecular and Cellular Biology. May, 2009 | Pubmed ID: 19255141 Targeted Killing of Cancer Cells in Vivo and in Vitro with EGF-directed Carbon Nanotube-based Drug Delivery ACS Nano. Feb, 2009 | Pubmed ID: 19236065 Intravital Two-photon Microscopy for Studying the Uptake and Trafficking of Fluorescently Conjugated Molecules in Live Rodents Traffic (Copenhagen, Denmark). Sep, 2008 | Pubmed ID: 18647170 Fluorescent Microscopy-based Assays to Study the Role of Rab22a in Clathrin-independent Endocytosis Methods in Enzymology. 2005 | Pubmed ID: 16473591 Multiple Activities for Arf1 at the Golgi Complex Biochimica Et Biophysica Acta. Jul, 2005 | Pubmed ID: 15979507 Rab22a Regulates the Recycling of Membrane Proteins Internalized Independently of Clathrin Molecular Biology of the Cell. Aug, 2004 | Pubmed ID: 15181155 Characterization of a Nonclathrin Endocytic Pathway: Membrane Cargo and Lipid Requirements Molecular Biology of the Cell. Aug, 2004 | Pubmed ID: 15146059 A Role for Arf1 in Mitotic Golgi Disassembly, Chromosome Segregation, and Cytokinesis Proceedings of the National Academy of Sciences of the United States of America. Nov, 2003 | Pubmed ID: 14585930 Convergence of Non-clathrin- and Clathrin-derived Endosomes Involves Arf6 Inactivation and Changes in Phosphoinositides Molecular Biology of the Cell. Feb, 2003 | Pubmed ID: 12589044 Intravital Subcellular Microscopy of the Mammary Gland JoVE 63674 Biologia Imaging Neutrophil Migration in the Mouse Skin to Investigate Subcellular Membrane Remodeling Under Physiological Conditions JoVE 63581 Biologia फ्लोरोसेंट प्रोटीन व्यक्त करते रहते चूहों में इमेजिंग subcellular संरचनाओं के लिए intravital माइक्रोस्कोपी Andrius Masedunskas1,2, Natalie Porat-Shliom1, Muhibullah Tora1, Oleg Milberg1,3, Roberto Weigert1 1Intracellular Membrane Trafficking Unit, Oral and Pharyngeal Cancer Branch National Institute of Dental and Craniofacial Research, National Institutes of Health, 2Department of Biology, University of North Carolina at Chapel Hill, 3Department of Chemical & Biochemical Engineering and Department of Biomedical Engineering, Rutgers University JoVE 50558 Biologia
Imaging Neutrophil Migration in the Mouse Skin to Investigate Subcellular Membrane Remodeling Under Physiological Conditions JoVE 63581 Biologia
फ्लोरोसेंट प्रोटीन व्यक्त करते रहते चूहों में इमेजिंग subcellular संरचनाओं के लिए intravital माइक्रोस्कोपी Andrius Masedunskas1,2, Natalie Porat-Shliom1, Muhibullah Tora1, Oleg Milberg1,3, Roberto Weigert1 1Intracellular Membrane Trafficking Unit, Oral and Pharyngeal Cancer Branch National Institute of Dental and Craniofacial Research, National Institutes of Health, 2Department of Biology, University of North Carolina at Chapel Hill, 3Department of Chemical & Biochemical Engineering and Department of Biomedical Engineering, Rutgers University JoVE 50558 Biologia