Rosalind A. Segal Department of Cancer Biology Dana-Farber Cancer Institute Biography Publications Institution JoVE Articles Rosalind A. Segal has not added a biography. If you are Rosalind A. Segal and would like to personalize this page please email our Author Liaison for assistance. Publications Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons Cell Reports. Oct, 2015 | Pubmed ID: 26489457 A Polyamine Twist on Hedgehog Signaling Developmental Cell. Oct, 2015 | Pubmed ID: 26460938 How Neuronal Activity Regulates Glioma Cell Proliferation Neuro-oncology. Sep, 2015 | Pubmed ID: 26359210 RAS/MAPK Activation Drives Resistance to Smo Inhibition, Metastasis, and Tumor Evolution in Shh Pathway-Dependent Tumors Cancer Research. Sep, 2015 | Pubmed ID: 26130651 The Eya1 Phosphatase Promotes Shh Signaling During Hindbrain Development and Oncogenesis Developmental Cell. Apr, 2015 | Pubmed ID: 25816987 Preserve and Protect: Maintaining Axons Within Functional Circuits Trends in Neurosciences. Oct, 2014 | Pubmed ID: 25167775 Shh-proteoglycan Interactions Regulate Maturation of Olfactory Glomerular Circuitry Developmental Neurobiology. Dec, 2014 | Pubmed ID: 24913191 Pediatric Low-grade Gliomas: How Modern Biology Reshapes the Clinical Field Biochimica Et Biophysica Acta. Apr, 2014 | Pubmed ID: 24589977 Neuronal Signaling Through Endocytosis Cold Spring Harbor Perspectives in Biology. Feb, 2014 | Pubmed ID: 24492712 New Progenitors NESTIN(g) in the EGL Nature Neuroscience. Dec, 2013 | Pubmed ID: 24270268 Coordinate Activation of Shh and PI3K Signaling in PTEN-deficient Glioblastoma: New Therapeutic Opportunities Nature Medicine. Nov, 2013 | Pubmed ID: 24076665 Heparan Sulfate Proteoglycans Containing a Glypican 5 Core and 2-O-sulfo-iduronic Acid Function As Sonic Hedgehog Co-receptors to Promote Proliferation The Journal of Biological Chemistry. Sep, 2013 | Pubmed ID: 23867465 Target-derived Neurotrophins Coordinate Transcription and Transport of Bclw to Prevent Axonal Degeneration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2013 | Pubmed ID: 23516285 From Synapse to Nucleus and Back Again--communication over Distance Within Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2011 | Pubmed ID: 22072654 Numb Links Extracellular Cues to Intracellular Polarity Machinery to Promote Chemotaxis Developmental Cell. May, 2011 | Pubmed ID: 21571219 Neuromuscular Junction Defects in Mice with Mutation of Dynein Heavy Chain 1 PloS One. 2011 | Pubmed ID: 21346813 Sensory Neuropathy Attributable to Loss of Bcl-w The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2011 | Pubmed ID: 21289171 The Longer U(T)R, the Further You Go Nature Neuroscience. Mar, 2010 | Pubmed ID: 20177416 Live or Let Die: CCM2 Provides the Link Neuron. Sep, 2009 | Pubmed ID: 19755097 Anterograde Transport of TrkB in Axons is Mediated by Direct Interaction with Slp1 and Rab27 Developmental Cell. May, 2009 | Pubmed ID: 19460344 A Retrograde Neuronal Survival Response: Target-derived Neurotrophins Regulate MEF2D and Bcl-w The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2009 | Pubmed ID: 19458239 Proteoglycan Interactions with Sonic Hedgehog Specify Mitogenic Responses Nature Neuroscience. Apr, 2009 | Pubmed ID: 19287388 Action in the Axon: Generation and Transport of Signaling Endosomes Current Opinion in Neurobiology. Jun, 2008 | Pubmed ID: 18778772 A Neuron-specific Cytoplasmic Dynein Isoform Preferentially Transports TrkB Signaling Endosomes The Journal of Cell Biology. Jun, 2008 | Pubmed ID: 18559670 Polarized Signaling Endosomes Coordinate BDNF-induced Chemotaxis of Cerebellar Precursors Neuron. Jul, 2007 | Pubmed ID: 17610817 CXCR4 Inhibition Synergizes with Cytotoxic Chemotherapy in Gliomas Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2006 | Pubmed ID: 17121897 Migration from a Mitogenic Niche Promotes Cell-cycle Exit The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2005 | Pubmed ID: 16280582 Subtracting the Math: Prominin-positive Cerebellar Stem Cells in White Matter Nature Neuroscience. Jun, 2005 | Pubmed ID: 15917830 Dynein Motors Transport Activated Trks to Promote Survival of Target-dependent Neurons Nature Neuroscience. Jun, 2004 | Pubmed ID: 15122257 A Small-molecule Antagonist of CXCR4 Inhibits Intracranial Growth of Primary Brain Tumors Proceedings of the National Academy of Sciences of the United States of America. Nov, 2003 | Pubmed ID: 14595012 Medulloblastoma Tumorigenesis Diverges from Cerebellar Granule Cell Differentiation in Patched Heterozygous Mice Developmental Biology. Nov, 2003 | Pubmed ID: 14568546 Growth, Survival and Migration: the Trk to Cancer Cancer Treatment and Research. 2003 | Pubmed ID: 12613191 Selectivity in Neurotrophin Signaling: Theme and Variations Annual Review of Neuroscience. 2003 | Pubmed ID: 12598680 Regional Expression of P75NTR Contributes to Neurotrophin Regulation of Cerebellar Patterning Molecular and Cellular Neurosciences. Jan, 2003 | Pubmed ID: 12595234 High-resolution Imaging Demonstrates Dynein-based Vesicular Transport of Activated Trk Receptors Journal of Neurobiology. Jun, 2002 | Pubmed ID: 12150505 Medulloblastomas and Primitive Neuroectodermal Tumors Rarely Contain Polyomavirus DNA Sequences Neuro-oncology. Jul, 2002 | Pubmed ID: 12084346 Retrograde Neurotrophin Signaling: Trk-ing Along the Axon Current Opinion in Neurobiology. Jun, 2002 | Pubmed ID: 12049932 Development (Cambridge, England). May, 2002 | Pubmed ID: 11959830 BDNF Stimulates Migration of Cerebellar Granule Cells Development (Cambridge, England). Mar, 2002 | Pubmed ID: 11880352 Location, Location, Location: a Spatial View of Neurotrophin Signal Transduction Trends in Neurosciences. Mar, 2002 | Pubmed ID: 11852149 Brain-derived Neurotrophic Factor Modulates Cerebellar Plasticity and Synaptic Ultrastructure The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2002 | Pubmed ID: 11850459 İlaç Tedavileri tümörün mikro incelenmesi ve Hedeflenen A Beyin Tümörü / Organotipik Dilim Co-kültür Sistemi Emily J. Chadwick1, David P. Yang1, Mariella G. Filbin2, Emanuele Mazzola3, Yu Sun1, Oded Behar1,4, Maria F. Pazyra-Murphy1, Liliana Goumnerova5, Keith L. Ligon6, Charles D. Stiles1, Rosalind A. Segal1 1Department of Cancer Biology, Dana-Farber Cancer Institute, 2Department of Pediatrics, Children's Hospital, 3Department of Biostatistics & Computational Biology, Dana-Farber Cancer Institute, 4Department of Developmental Biology and Cancer Research, Hebrew University of Jerusalem, 5Department of Neurosurgery, Children's Hospital, 6Center for Molecular Oncologic Pathology, Department of Medical Oncology, Dana-Farber Cancer Institute Medicina
İlaç Tedavileri tümörün mikro incelenmesi ve Hedeflenen A Beyin Tümörü / Organotipik Dilim Co-kültür Sistemi Emily J. Chadwick1, David P. Yang1, Mariella G. Filbin2, Emanuele Mazzola3, Yu Sun1, Oded Behar1,4, Maria F. Pazyra-Murphy1, Liliana Goumnerova5, Keith L. Ligon6, Charles D. Stiles1, Rosalind A. Segal1 1Department of Cancer Biology, Dana-Farber Cancer Institute, 2Department of Pediatrics, Children's Hospital, 3Department of Biostatistics & Computational Biology, Dana-Farber Cancer Institute, 4Department of Developmental Biology and Cancer Research, Hebrew University of Jerusalem, 5Department of Neurosurgery, Children's Hospital, 6Center for Molecular Oncologic Pathology, Department of Medical Oncology, Dana-Farber Cancer Institute Medicina