Saba Parvez Department of Pharmacology and Toxicology, College of Pharmacy University of Utah Biography Publications Institution JoVE Articles Saba Parvez has not added a biography. If you are Saba Parvez and would like to personalize this page please email our Author Liaison for assistance. Publications Large-scale F0 CRISPR Screens in Vivo Using MIC-Drop Nature Protocols. Apr, 2023 | Pubmed ID: 37069311 Z-REX: Shepherding Reactive Electrophiles to Specific Proteins Expressed Tissue Specifically or Ubiquitously, and Recording the Resultant Functional Electrophile-induced Redox Responses in Larval Fish Nature Protocols. May, 2023 | Pubmed ID: 37020146 Z-REX Uncovers a Bifurcation in Function of Keap1 Paralogs ELife. Oct, 2022 | Pubmed ID: 36300632 Wdr1 and Cofilin Are Necessary Mediators of Immune-cell-specific Apoptosis Triggered by Tecfidera Nature Communications. Sep, 2021 | Pubmed ID: 34593792 MIC-Drop: A Platform for Large-scale in Vivo CRISPR Screens Science (New York, N.Y.). Sep, 2021 | Pubmed ID: 34413171 Isonitrile-responsive and Bioorthogonally Removable Tetrazine Protecting Groups Chemical Science. Jan, 2020 | Pubmed ID: 32110368 Stable, Reactive, and Orthogonal Tetrazines: Dispersion Forces Promote the Cycloaddition with Isonitriles Angewandte Chemie (International Ed. in English). Jul, 2019 | Pubmed ID: 31062496 Redox Signaling by Reactive Electrophiles and Oxidants Chemical Reviews. Sep, 2018 | Pubmed ID: 30148624 Bioorthogonal Removal of 3-Isocyanopropyl Groups Enables the Controlled Release of Fluorophores and Drugs in Vivo Journal of the American Chemical Society. Jul, 2018 | Pubmed ID: 29927585 Monitoring On-Target Signaling Responses in Larval Zebrafish - Z-REX Unmasks Precise Mechanisms of Electrophilic Drugs and Metabolites Kuan-Ting Huang1, Phillippe Ly1, Jesse R. Poganik2, Saba Parvez3, Marcus J. C. Long4, Yimon Aye1 1Swiss Federal Institute of Technology Lausanne (EPFL), 2Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, 3Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, 4University of Lausanne (UNIL) JoVE 64846 Biologia
Monitoring On-Target Signaling Responses in Larval Zebrafish - Z-REX Unmasks Precise Mechanisms of Electrophilic Drugs and Metabolites Kuan-Ting Huang1, Phillippe Ly1, Jesse R. Poganik2, Saba Parvez3, Marcus J. C. Long4, Yimon Aye1 1Swiss Federal Institute of Technology Lausanne (EPFL), 2Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, 3Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, 4University of Lausanne (UNIL) JoVE 64846 Biologia