Scott A. Weed Department of Neurobiology and Anatomy West Virginia University Biography Publications Institution JoVE Articles Scott A. Weed has not added a biography. If you are Scott A. Weed and would like to personalize this page please email our Author Liaison for assistance. Publications Tumor and Stromal-based Contributions to Head and Neck Squamous Cell Carcinoma Invasion Cancers. 2015 | Pubmed ID: 25734659 Use of High Frequency Ultrasound to Monitor Cervical Lymph Node Alterations in Mice PloS One. 2014 | Pubmed ID: 24955984 NEDD9 Regulates Actin Dynamics Through Cortactin Deacetylation in an AURKA/HDAC6-dependent Manner Molecular Cancer Research : MCR. May, 2014 | Pubmed ID: 24574519 NEDD9 Depletion Leads to MMP14 Inactivation by TIMP2 and Prevents Invasion and Metastasis Molecular Cancer Research : MCR. Jan, 2014 | Pubmed ID: 24202705 Metastatic MTLn3 and Non-metastatic MTC Adenocarcinoma Cells Can Be Differentiated by Pseudomonas Aeruginosa Biology Open. 2013 | Pubmed ID: 24143275 Phosphorylation of the Alternative MRNA Splicing Factor 45 (SPF45) by Clk1 Regulates Its Splice Site Utilization, Cell Migration and Invasion Nucleic Acids Research. May, 2013 | Pubmed ID: 23519612 Src Binds Cortactin Through an SH2 Domain Cystine-mediated Linkage Journal of Cell Science. Dec, 2012 | Pubmed ID: 23097045 Effects of Tobacco Smoking and Nicotine on Cancer Treatment Pharmacotherapy. Oct, 2012 | Pubmed ID: 23033231 Cortactin is a Substrate of Activated Cdc42-associated Kinase 1 (ACK1) During Ligand-induced Epidermal Growth Factor Receptor Downregulation PloS One. 2012 | Pubmed ID: 22952966 Effects of Tobacco Smoking and Nicotine on Cancer Treatment Pharmacotherapy. Aug, 2012 | Pubmed ID: 22887142 Recently Identified Biomarkers That Promote Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma Cancers. 2011 | Pubmed ID: 24212639 Further Insights into Cortactin Conformational Regulation Bioarchitecture. 1, 2011 | Pubmed ID: 21866257 Revisiting the ERK/Src Cortactin Switch Communicative & Integrative Biology. Mar, 2011 | Pubmed ID: 21655441 Cortactin Phosphorylated by ERK1/2 Localizes to Sites of Dynamic Actin Regulation and is Required for Carcinoma Lamellipodia Persistence PloS One. 2010 | Pubmed ID: 21079800 Oncogenic Src Requires a Wild-type Counterpart to Regulate Invadopodia Maturation Journal of Cell Science. Nov, 2010 | Pubmed ID: 20980387 Saracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia Function Journal of Cancer Science & Therapy. Nov, 2009 | Pubmed ID: 20505783 Cortactin is a Functional Target of E-cadherin-activated Src Family Kinases in MCF7 Epithelial Monolayers The Journal of Biological Chemistry. Jul, 2009 | Pubmed ID: 19457864 Cortactin Branches Out: Roles in Regulating Protrusive Actin Dynamics Cell Motility and the Cytoskeleton. Sep, 2008 | Pubmed ID: 18615630 Phosphorylation of AFAP-110 Affects Podosome Lifespan in A7r5 Cells Journal of Cell Science. Jul, 2008 | Pubmed ID: 18577577 Actin Cytoskeletal Mediators of Motility and Invasion Amplified and Overexpressed in Head and Neck Cancer Clinical & Experimental Metastasis. 2008 | Pubmed ID: 18324357 PI3K Activation is Required for PMA-directed Activation of CSrc by AFAP-110 American Journal of Physiology. Cell Physiology. Jul, 2007 | Pubmed ID: 17360811 Overexpression of Cyclin D1 and Cortactin is Primarily Independent of Gene Amplification in Salivary Gland Adenoid Cystic Carcinoma Oral Oncology. Sep, 2007 | Pubmed ID: 17113340 Cortactin Overexpression Regulates Actin-related Protein 2/3 Complex Activity, Motility, and Invasion in Carcinomas with Chromosome 11q13 Amplification Cancer Research. Aug, 2006 | Pubmed ID: 16912177 Protein Kinase Calpha Activates C-Src and Induces Podosome Formation Via AFAP-110 Molecular and Cellular Biology. Sep, 2004 | Pubmed ID: 15314167 Cortactin and Crk Cooperate to Trigger Actin Polymerization During Shigella Invasion of Epithelial Cells The Journal of Cell Biology. Jul, 2004 | Pubmed ID: 15263018 Actin Depolymerization-induced Tyrosine Phosphorylation of Cortactin: the Role of Fer Kinase The Biochemical Journal. Jun, 2004 | Pubmed ID: 15030313 Cortactin is Necessary for E-cadherin-mediated Contact Formation and Actin Reorganization The Journal of Cell Biology. Mar, 2004 | Pubmed ID: 15024035 Characterization of an Ankyrin Repeat-containing Shank2 Isoform (Shank2E) in Liver Epithelial Cells The Biochemical Journal. May, 2004 | Pubmed ID: 14977424 Rac2D57N, a Dominant Inhibitory Rac2 Mutant That Inhibits P38 Kinase Signaling and Prevents Surface Ruffling in Bone-marrow-derived Macrophages Journal of Cell Science. Jan, 2004 | Pubmed ID: 14676277 Cortactin Tyrosine Phosphorylation Requires Rac1 Activity and Association with the Cortical Actin Cytoskeleton Molecular Biology of the Cell. Aug, 2003 | Pubmed ID: 12925758 MEKK1 Regulates Calpain-dependent Proteolysis of Focal Adhesion Proteins for Rear-end Detachment of Migrating Fibroblasts The EMBO Journal. Jul, 2003 | Pubmed ID: 12839996 Cortactin Interacts with WIP in Regulating Arp2/3 Activation and Membrane Protrusion Current Biology : CB. Mar, 2003 | Pubmed ID: 12620186 Dynamin2 and Cortactin Regulate Actin Assembly and Filament Organization Current Biology : CB. Oct, 2002 | Pubmed ID: 12419186 High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes Elyse L. Walk*1,3, Sarah L. McLaughlin*2,3, Scott A. Weed1,3 1Department of Neurobiology and Anatomy, West Virginia University, 2Animal Models and Imaging Facility, West Virginia University, 3Mary Babb Randolph Cancer Center, West Virginia University JoVE 52718 Medicina Quantitative Measurement of Invadopodia-mediated Extracellular Matrix Proteolysis in Single and Multicellular Contexts Karen H. Martin1, Karen E. Hayes1, Elyse L. Walk1, Amanda Gatesman Ammer1, Steven M. Markwell1, Scott A. Weed1 1Department of Neurobiology and Anatomy, Program in Cancer Cell Biology, Mary Babb Randolph Cancer Center, West Virginia University JoVE 4119 Biologia Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma Amanda Gatesman Ammer1, Karen E. Hayes1, Karen H. Martin1, Lingqing Zhang2, George A. Spirou3, Scott A. Weed1 1Department of Neurobiology and Anatomy, Program in Cancer Cell Biology, Mary Babb Randolph Cancer Center, West Virginia University, 2Sensory Neuroscience Research Center, West Virginia University, 3Departments of Otolaryngology and Physiology, Center for Neuroscience, West Virginia University JoVE 2941 Medicina
High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes Elyse L. Walk*1,3, Sarah L. McLaughlin*2,3, Scott A. Weed1,3 1Department of Neurobiology and Anatomy, West Virginia University, 2Animal Models and Imaging Facility, West Virginia University, 3Mary Babb Randolph Cancer Center, West Virginia University JoVE 52718 Medicina
Quantitative Measurement of Invadopodia-mediated Extracellular Matrix Proteolysis in Single and Multicellular Contexts Karen H. Martin1, Karen E. Hayes1, Elyse L. Walk1, Amanda Gatesman Ammer1, Steven M. Markwell1, Scott A. Weed1 1Department of Neurobiology and Anatomy, Program in Cancer Cell Biology, Mary Babb Randolph Cancer Center, West Virginia University JoVE 4119 Biologia
Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma Amanda Gatesman Ammer1, Karen E. Hayes1, Karen H. Martin1, Lingqing Zhang2, George A. Spirou3, Scott A. Weed1 1Department of Neurobiology and Anatomy, Program in Cancer Cell Biology, Mary Babb Randolph Cancer Center, West Virginia University, 2Sensory Neuroscience Research Center, West Virginia University, 3Departments of Otolaryngology and Physiology, Center for Neuroscience, West Virginia University JoVE 2941 Medicina