Simon Alford Department of Anatomy and Cell Biology University of Illinois at Chicago College of Medicine Biography Publications Institution JoVE Articles Simon Alford has not added a biography. If you are Simon Alford and would like to personalize this page please email our Author Liaison for assistance. Publications Quantitation and Simulation of Single Action Potential-evoked Ca Signals in CA1 Pyramidal Neuron Presynaptic Terminals ENeuro. Sep, 2019 | Pubmed ID: 31551250 Physiological Roles for Neuromodulation Via G GPCRs Working Through Gβγ-SNARE Interaction Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Sep, 2019 | Pubmed ID: 31477818 Extracellular and Intracellular Sphingosine-1-phosphate Distinctly Regulates Exocytosis in Chromaffin Cells Journal of Neurochemistry. Jun, 2019 | Pubmed ID: 30963576 Disabling the Gβγ-SNARE Interaction Disrupts GPCR-mediated Presynaptic Inhibition, Leading to Physiological and Behavioral Phenotypes Science Signaling. Feb, 2019 | Pubmed ID: 30783011 Gβγ SNARE Interactions and Their Behavioral Effects Neurochemical Research. Mar, 2019 | Pubmed ID: 29752624 Gβγ Directly Modulates Vesicle Fusion by Competing with Synaptotagmin for Binding to Neuronal SNARE Proteins Embedded in Membranes The Journal of Biological Chemistry. 07, 2017 | Pubmed ID: 28515322 A Descending Dopamine Pathway Conserved from Basal Vertebrates to Mammals Proceedings of the National Academy of Sciences of the United States of America. Apr, 2016 | Pubmed ID: 27071118 Sensory Activation of Command Cells for Locomotion and Modulatory Mechanisms: Lessons from Lampreys Frontiers in Neural Circuits. 2016 | Pubmed ID: 27047342 A Synaptic Mechanism for Network Synchrony Frontiers in Cellular Neuroscience. 2014 | Pubmed ID: 25278839 The NHS Health Check Programme in England: a Qualitative Study Health Promotion International. Jul, 2014 | Pubmed ID: 25073761 Modulation of Neurotransmission by GPCRs is Dependent Upon the Microarchitecture of the Primed Vesicle Complex The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2014 | Pubmed ID: 24381287 Fluorescent Imaging Reports an Extracellular Alkalinization Induced by Glutamatergic Activation of Isolated Retinal Horizontal Cells Journal of Neurophysiology. Mar, 2014 | Pubmed ID: 24335210 Forebrain Dopamine Neurons Project Down to a Brainstem Region Controlling Locomotion Proceedings of the National Academy of Sciences of the United States of America. Aug, 2013 | Pubmed ID: 23918379 Synaptic NMDA Receptor-dependent Ca²⁺ Entry Drives Membrane Potential and Ca²⁺ Oscillations in Spinal Ventral Horn Neurons PloS One. 2013 | Pubmed ID: 23646190 Differential Regulation of Synaptic Transmission by Pre- and Postsynaptic SK Channels in the Spinal Locomotor Network Journal of Neurophysiology. Jun, 2013 | Pubmed ID: 23554432 Role of Presynaptic Metabotropic Glutamate Receptors in the Induction of Long-term Synaptic Plasticity of Vesicular Release Neuropharmacology. Mar, 2013 | Pubmed ID: 22626985 Gβγ Inhibits Exocytosis Via Interaction with Critical Residues on Soluble N-ethylmaleimide-sensitive Factor Attachment Protein-25 Molecular Pharmacology. Dec, 2012 | Pubmed ID: 22962332 Dual Pools of Actin at Presynaptic Terminals Journal of Neurophysiology. Jun, 2012 | Pubmed ID: 22457456 Extracellular PH Dynamics of Retinal Horizontal Cells Examined Using Electrochemical and Fluorometric Methods Journal of Neurophysiology. Feb, 2012 | Pubmed ID: 22090459 Spotlight on the Active Zone Cellular Logistics. 5, 2011 | Pubmed ID: 21922071 Phosphorylation-state-dependent Regulation of NMDA Receptor Short-term Plasticity Modifies Hippocampal Dendritic Ca2+ Transients Journal of Neurophysiology. Oct, 2010 | Pubmed ID: 20719921 New Perspectives on the Dialogue Between Brains and Machines Frontiers in Neuroscience. 2010 | Pubmed ID: 20589094 A Parallel Cholinergic Brainstem Pathway for Enhancing Locomotor Drive Nature Neuroscience. Jun, 2010 | Pubmed ID: 20473293 Presynaptic G-protein-coupled Receptors Dynamically Modify Vesicle Fusion, Synaptic Cleft Glutamate Concentrations, and Motor Behavior The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2009 | Pubmed ID: 19692597 Brain-machine Interactions for Assessing the Dynamics of Neural Systems Frontiers in Neurorobotics. 2009 | Pubmed ID: 19430593 Gbetagamma Interferes with Ca2+-dependent Binding of Synaptotagmin to the Soluble N-ethylmaleimide-sensitive Factor Attachment Protein Receptor (SNARE) Complex Molecular Pharmacology. Nov, 2007 | Pubmed ID: 17715396 Presynaptic G-protein-coupled Receptors Regulate Synaptic Cleft Glutamate Via Transient Vesicle Fusion The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2007 | Pubmed ID: 17537956 G Protein Betagamma-subunits Activated by Serotonin Mediate Presynaptic Inhibition by Regulating Vesicle Fusion Properties Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006 | Pubmed ID: 16537522 Location and Function of Vesicle Clusters, Active Zones and Ca2+ Channels in the Lamprey Presynaptic Terminal The Journal of Physiology. Nov, 2005 | Pubmed ID: 16141275 Computational Analysis in Vitro: Dynamics and Plasticity of a Neuro-robotic System Journal of Neural Engineering. Sep, 2005 | Pubmed ID: 16135888 Gbetagamma Acts at the C Terminus of SNAP-25 to Mediate Presynaptic Inhibition Nature Neuroscience. May, 2005 | Pubmed ID: 15834421 G Protein Betagamma Directly Regulates SNARE Protein Fusion Machinery for Secretory Granule Exocytosis Nature Neuroscience. Apr, 2005 | Pubmed ID: 15778713 5-HT Prolongs Ventral Root Bursting Via Presynaptic Inhibition of Synaptic Activity During Fictive Locomotion in Lamprey Journal of Neurophysiology. Feb, 2005 | Pubmed ID: 15456802 Quantitative Investigation of Calcium Signals for Locomotor Pattern Generation in the Lamprey Spinal Cord Journal of Neurophysiology. Sep, 2004 | Pubmed ID: 15140901 The Pharmacology of Vertebrate Spinal Central Pattern Generators The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. Jun, 2003 | Pubmed ID: 15065817 Dynamical Dimension of a Hybrid Neurorobotic System IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society. Jun, 2003 | Pubmed ID: 12899261 The Requirement of Presynaptic Metabotropic Glutamate Receptors for the Maintenance of Locomotion The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2002 | Pubmed ID: 11978845 Calcium Influx-independent Depression of Transmitter Release by 5-HT at Lamprey Spinal Cord Synapses The Journal of Physiology. Apr, 2001 | Pubmed ID: 11306653 Presynaptic GABAA and GABAB Receptor-mediated Phasic Modulation in Axons of Spinal Motor Interneurons The European Journal of Neuroscience. 1991 | Pubmed ID: 12106209 Laminectomy and Spinal Cord Window Implantation in the Mouse Elizabeth A. Pietruczyk1, Terilyn K.L. Stephen2, Simon Alford1, Sarah E. Lutz1 1Department of Anatomy and Cell Biology, University of Illinois at Chicago College of Medicine, 2Medical Scientist Training Program, University of Illinois at Chicago College of Medicine JoVE 58330 Neuroscienze In Vivo Calcium Imaging in C. elegans Body Wall Muscles Ashley A. Martin1,2, Simon Alford3, Janet E. Richmond1 1Department of Biological Sciences, University of Illinois at Chicago, 2Department of Integrative Biology and Physiology, University of Minnesota, 3Department of Anatomy and Cell Biology, University of Illinois at Chicago JoVE 59175 Biochimica Acute Dissociation of Lamprey Reticulospinal Axons to Enable Recording from the Release Face Membrane of Individual Functional Presynaptic Terminals Shankar Ramachandran1, Simon Alford1 1Biological Sciences, University of Illinois at Chicago JoVE 51925 Neuroscienze
Laminectomy and Spinal Cord Window Implantation in the Mouse Elizabeth A. Pietruczyk1, Terilyn K.L. Stephen2, Simon Alford1, Sarah E. Lutz1 1Department of Anatomy and Cell Biology, University of Illinois at Chicago College of Medicine, 2Medical Scientist Training Program, University of Illinois at Chicago College of Medicine JoVE 58330 Neuroscienze
In Vivo Calcium Imaging in C. elegans Body Wall Muscles Ashley A. Martin1,2, Simon Alford3, Janet E. Richmond1 1Department of Biological Sciences, University of Illinois at Chicago, 2Department of Integrative Biology and Physiology, University of Minnesota, 3Department of Anatomy and Cell Biology, University of Illinois at Chicago JoVE 59175 Biochimica
Acute Dissociation of Lamprey Reticulospinal Axons to Enable Recording from the Release Face Membrane of Individual Functional Presynaptic Terminals Shankar Ramachandran1, Simon Alford1 1Biological Sciences, University of Illinois at Chicago JoVE 51925 Neuroscienze