Stuart C. Sealfon Center for Translational Systems Biology and Department of Neurology Mount Sinai School of Medicine Biography Publications Institution JoVE Articles Stuart C. Sealfon has not added a biography. If you are Stuart C. Sealfon and would like to personalize this page please email our Author Liaison for assistance. Publications Optimized Amplification and Single-cell Analysis Identify GnRH-mediated Activation of Rap1b in Primary Rat Gonadotropes Molecular and Cellular Endocrinology. Mar, 2012 | Pubmed ID: 22127306 Multi-scale Stochastic Simulation of Diffusion-coupled Agents and Its Application to Cell Culture Simulation PloS One. 2011 | Pubmed ID: 22216238 Decoding the Signaling of a GPCR Heteromeric Complex Reveals a Unifying Mechanism of Action of Antipsychotic Drugs Cell. Nov, 2011 | Pubmed ID: 22118459 Authors Response to Correspondence About an Improved Compensation Method Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Dec, 2011 | Pubmed ID: 22065546 Functional Crosstalk and Heteromerization of Serotonin 5-HT2A and Dopamine D2 Receptors Neuropharmacology. Sep, 2011 | Pubmed ID: 21645528 Improved Compensation in Flow Cytometry by Multivariable Optimization Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2011 | Pubmed ID: 21485003 Characterization of a MAPK Scaffolding Protein Logic Gate in Gonadotropes Molecular Endocrinology (Baltimore, Md.). Jun, 2011 | Pubmed ID: 21436256 Differential Gene Expression in Patients with Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. Jul, 2011 | Pubmed ID: 21375368 Role of Cell-to-cell Variability in Activating a Positive Feedback Antiviral Response in Human Dendritic Cells PloS One. 2011 | Pubmed ID: 21347441 Metabotropic Glutamate MGlu2 Receptor is Necessary for the Pharmacological and Behavioral Effects Induced by Hallucinogenic 5-HT2A Receptor Agonists Neuroscience Letters. Apr, 2011 | Pubmed ID: 21276828 RNA and DNA Microarrays Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 20967621 Misty Mountain Clustering: Application to Fast Unsupervised Flow Cytometry Gating BMC Bioinformatics. 2010 | Pubmed ID: 20932336 Signaling Network of Dendritic Cells in Response to Pathogens: a Community-input Supported Knowledgebase BMC Systems Biology. 2010 | Pubmed ID: 20929569 Validation of Efficient High-throughput Plasmid and SiRNA Transfection of Human Monocyte-derived Dendritic Cells Without Cell Maturation Journal of Immunological Methods. Dec, 2010 | Pubmed ID: 20875421 Novel Nipah Virus Immune-antagonism Strategy Revealed by Experimental and Computational Study Journal of Virology. Nov, 2010 | Pubmed ID: 20739535 Heteromerization of G Protein-coupled Receptors: Relevance to Neurological Disorders and Neurotherapeutics CNS & Neurological Disorders Drug Targets. Nov, 2010 | Pubmed ID: 20632964 Research Resource: Gonadotropin-releasing Hormone Receptor-mediated Signaling Network in LbetaT2 Cells: a Pathway-based Web-accessible Knowledgebase Molecular Endocrinology (Baltimore, Md.). Sep, 2010 | Pubmed ID: 20592162 Plato's Cave Algorithm: Inferring Functional Signaling Networks from Early Gene Expression Shadows PLoS Computational Biology. Jun, 2010 | Pubmed ID: 20585619 Coregulation Mapping Based on Individual Phenotypic Variation in Response to Virus Infection Immunome Research. 2010 | Pubmed ID: 20298589 Antiviral Response Dictated by Choreographed Cascade of Transcription Factors Journal of Immunology (Baltimore, Md. : 1950). Mar, 2010 | Pubmed ID: 20164420 Immune Response Modeling of Interferon Beta-pretreated Influenza Virus-infected Human Dendritic Cells Biophysical Journal. Feb, 2010 | Pubmed ID: 20159146 Multiple Testing and Its Applications to Microarrays Statistical Methods in Medical Research. Dec, 2009 | Pubmed ID: 20048384 Group II Metabotropic Glutamate Receptors and Schizophrenia Cellular and Molecular Life Sciences : CMLS. Dec, 2009 | Pubmed ID: 19707855 Model of Autocrine/paracrine Signaling in Epithelial Layer: Geometrical Regulation of Intercellular Communication The Journal of Physical Chemistry. B. Aug, 2009 | Pubmed ID: 19601596 Microtranscriptome Regulation by Gonadotropin-releasing Hormone Molecular and Cellular Endocrinology. Apr, 2009 | Pubmed ID: 19356622 Agonist-trafficking and Hallucinogens Current Medicinal Chemistry. 2009 | Pubmed ID: 19275609 Psychedelics and Schizophrenia Trends in Neurosciences. Apr, 2009 | Pubmed ID: 19269047 SOME STEP-DOWN PROCEDURES CONTROLLING THE FALSE DISCOVERY RATE UNDER DEPENDENCE Statistica Sinica. 2008 | Pubmed ID: 19018297 Antiviral-activated Dendritic Cells: a Paracrine-induced Response State Journal of Immunology (Baltimore, Md. : 1950). Nov, 2008 | Pubmed ID: 18981106 Interferon-beta Pretreatment of Conventional and Plasmacytoid Human Dendritic Cells Enhances Their Activation by Influenza Virus PLoS Pathogens. Oct, 2008 | Pubmed ID: 18974865 A Comprehensive Evaluation of Human Plasmacytoid Dendritic Cells Using Small Volumes of Human Blood Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Aug, 2008 | Pubmed ID: 18729740 Receptor Pair for Schizophrenia Pediatric Research. Jul, 2008 | Pubmed ID: 18574404 Cell-to-cell Communication: Time and Length Scales of Ligand Internalization in Cultures of Suspended Cells The Journal of Chemical Physics. Jun, 2008 | Pubmed ID: 18554059 Getting Started in Biological Pathway Construction and Analysis PLoS Computational Biology. Feb, 2008 | Pubmed ID: 18463709 Identification of a Serotonin/glutamate Receptor Complex Implicated in Psychosis Nature. Mar, 2008 | Pubmed ID: 18297054 Time and Length Scales of Autocrine Signals in Three Dimensions Biophysical Journal. Sep, 2007 | Pubmed ID: 17720734 Noise Propagation and Scaling in Regulation of Gonadotrope Biosynthesis Biophysical Journal. Dec, 2007 | Pubmed ID: 17720728 Chromosome-specific and Noisy IFNB1 Transcription in Individual Virus-infected Human Primary Dendritic Cells Nucleic Acids Research. 2007 | Pubmed ID: 17675303 BioPP: a Tool for Web-publication of Biological Networks BMC Bioinformatics. 2007 | Pubmed ID: 17519033 Bone Morphogenetic Protein 2 and Activin A Synergistically Stimulate Follicle-stimulating Hormone Beta Subunit Transcription Journal of Molecular Endocrinology. Feb, 2007 | Pubmed ID: 17293449 Biphasic Effects of Postnatal Exposure to Diethylhexylphthalate on the Timing of Puberty in Male Rats Journal of Andrology. Jul-Aug, 2007 | Pubmed ID: 17287459 Hallucinogens Recruit Specific Cortical 5-HT(2A) Receptor-mediated Signaling Pathways to Affect Behavior Neuron. Feb, 2007 | Pubmed ID: 17270739 P53 Mediates Nontranscriptional Cell Death in Dopaminergic Cells in Response to Proteasome Inhibition The Journal of Biological Chemistry. Dec, 2006 | Pubmed ID: 17060322 Mixed Analog/digital Gonadotrope Biosynthetic Response to Gonadotropin-releasing Hormone The Journal of Biological Chemistry. Oct, 2006 | Pubmed ID: 16916798 Cortical 5-HT2A Receptor Signaling Modulates Anxiety-like Behaviors in Mice Science (New York, N.Y.). Jul, 2006 | Pubmed ID: 16873667 Influenza Virus Evades Innate and Adaptive Immunity Via the NS1 Protein Journal of Virology. Jul, 2006 | Pubmed ID: 16775317 The Human Herpesvirus 8 Chemokine Receptor VGPCR Triggers Autonomous Proliferation of Endothelial Cells The Journal of Clinical Investigation. May, 2006 | Pubmed ID: 16604194 Chronic Exposure to TNF-alpha Increases Airway Mucus Gene Expression in Vivo The Journal of Allergy and Clinical Immunology. Dec, 2005 | Pubmed ID: 16337454 Method for Multiplex Cellular Detection of MRNAs Using Quantum Dot Fluorescent in Situ Hybridization Nucleic Acids Research. 2005 | Pubmed ID: 16224100 Transcript Profiling of Immediate Early Genes Reveals a Unique Role for Activating Transcription Factor 3 in Mediating Activation of the Glycoprotein Hormone Alpha-subunit Promoter by Gonadotropin-releasing Hormone Molecular Endocrinology (Baltimore, Md.). Oct, 2005 | Pubmed ID: 15961508 Local Protein Synthesis Mediates a Rapid Increase in Dendritic Elongation Factor 1A After Induction of Late Long-term Potentiation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2005 | Pubmed ID: 15958750 Teaching Resources. G-protein-coupled Receptors Science's STKE : Signal Transduction Knowledge Environment. Apr, 2005 | Pubmed ID: 15827322 Acute Induction of Gene Expression in Brain and Liver by Insulin-induced Hypoglycemia Diabetes. Apr, 2005 | Pubmed ID: 15793232 CXC Chemokine Receptors on Human Oligodendrocytes: Implications for Multiple Sclerosis Brain : a Journal of Neurology. May, 2005 | Pubmed ID: 15774504 Epsilon-sarcoglycan Immunoreactivity and MRNA Expression in Mouse Brain The Journal of Comparative Neurology. Jan, 2005 | Pubmed ID: 15612018 Mutational Analysis of the Serotonin Receptor 5HT2c in Severe Early-onset Human Obesity Canadian Journal of Physiology and Pharmacology. Jun, 2004 | Pubmed ID: 15381968 Genomics View of Gonadotrope Signaling Circuits Trends in Endocrinology and Metabolism: TEM. Sep, 2004 | Pubmed ID: 15350605 Mining Microarrays for Metabolic Meaning: Nutritional Regulation of Hypothalamic Gene Expression Neurochemical Research. Jun, 2004 | Pubmed ID: 15176466 Early Single Cell Bifurcation of Pro- and Antiapoptotic States During Oxidative Stress The Journal of Biological Chemistry. Jun, 2004 | Pubmed ID: 15078887 Focused Microarray Analysis Methods (San Diego, Calif.). Dec, 2003 | Pubmed ID: 14597315 Structure of the GnRH Receptor-stimulated Signaling Network: Insights from Genomics Frontiers in Neuroendocrinology. Jul, 2003 | Pubmed ID: 14596811 Transcriptome Fingerprints Distinguish Hallucinogenic and Nonhallucinogenic 5-hydroxytryptamine 2A Receptor Agonist Effects in Mouse Somatosensory Cortex The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2003 | Pubmed ID: 14523084 Agonist-specific Transactivation of Phosphoinositide 3-kinase Signaling Pathway Mediated by the Dopamine D2 Receptor The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 12970364 Activation of Phosphoinositide 3-kinase by D2 Receptor Prevents Apoptosis in Dopaminergic Cell Lines The Biochemical Journal. Jul, 2003 | Pubmed ID: 12683952 Molecular Basis of Partial Agonism: Orientation of Indoleamine Ligands in the Binding Pocket of the Human Serotonin 5-HT2A Receptor Determines Relative Efficacy Molecular Pharmacology. Jan, 2003 | Pubmed ID: 12488534 Validated Genomic Approach to Study Differentially Expressed Genes in Complex Tissues Neurochemical Research. Oct, 2002 | Pubmed ID: 12462402 Conserved Helix 7 Tyrosine Acts As a Multistate Conformational Switch in the 5HT2C Receptor. Identification of a Novel "locked-on" Phenotype and Double Revertant Mutations The Journal of Biological Chemistry. Sep, 2002 | Pubmed ID: 12145300 Coupling of GnRH Concentration and the GnRH Receptor-activated Gene Program Molecular Endocrinology (Baltimore, Md.). Jun, 2002 | Pubmed ID: 12040003 Accuracy and Calibration of Commercial Oligonucleotide and Custom CDNA Microarrays Nucleic Acids Research. May, 2002 | Pubmed ID: 12000853 Monitoring G-protein-coupled Receptor Signaling with DNA Microarrays and Real-time Polymerase Chain Reaction Methods in Enzymology. 2002 | Pubmed ID: 11665639 Strategies for Mapping the Binding Site of the Serotonin 5-HT2A Receptor Methods in Enzymology. 2002 | Pubmed ID: 11665561 Optimized Protocol for Efficient Transfection of Dendritic Cells without Cell Maturation Robert Bowles*1, Sonali Patil*1, Hanna Pincas1, Stuart C. Sealfon1 1Center for Translational Systems Biology and Department of Neurology, Mount Sinai School of Medicine JoVE 2766 Immunologia e infezioni
Optimized Protocol for Efficient Transfection of Dendritic Cells without Cell Maturation Robert Bowles*1, Sonali Patil*1, Hanna Pincas1, Stuart C. Sealfon1 1Center for Translational Systems Biology and Department of Neurology, Mount Sinai School of Medicine JoVE 2766 Immunologia e infezioni