Sudarshan Rajagopal Department of Medicine Duke University Medical Center Biography Publications Institution JoVE Articles Sudarshan Rajagopal has not added a biography. If you are Sudarshan Rajagopal and would like to personalize this page please email our Author Liaison for assistance. Publications The β-arrestins: Multifunctional Regulators of G Protein-coupled Receptors The Journal of Biological Chemistry. Mar, 2016 | Pubmed ID: 26984408 Safety and Tolerability of High-dose Inhaled Treprostinil in Pulmonary Hypertension Journal of Cardiovascular Pharmacology. Apr, 2016 | Pubmed ID: 26828324 Use of Outcome Measures in Pulmonary Hypertension Clinical Trials American Heart Journal. Sep, 2015 | Pubmed ID: 26385024 The Influence of Angle of Insonation and Target Depth on Speckle-tracking Strain Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. May, 2015 | Pubmed ID: 25655402 What is Biased Efficacy? Defining the Relationship Between Intrinsic Efficacy and Free Energy Coupling Trends in Pharmacological Sciences. Dec, 2014 | Pubmed ID: 25448316 Monitoring Protein Conformational Changes and Dynamics Using Stable-isotope Labeling and Mass Spectrometry Nature Protocols. 2014 | Pubmed ID: 24810039 Comprehensive Assessment of Right Ventricular Function in Patients with Pulmonary Hypertension with Global Longitudinal Peak Systolic Strain Derived from Multiple Right Ventricular Views Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. Jun, 2014 | Pubmed ID: 24656881 Right Ventricular Mechanics Using a Novel Comprehensive Three-view Echocardiographic Strain Analysis in a Normal Population Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. Apr, 2014 | Pubmed ID: 24508364 Biased Agonism As a Mechanism for Differential Signaling by Chemokine Receptors The Journal of Biological Chemistry. Oct, 2013 | Pubmed ID: 24145037 Quantifying Biased Agonism: Understanding the Links Between Affinity and Efficacy Nature Reviews. Drug Discovery. Jun, 2013 | Pubmed ID: 23681006 Distinct Phosphorylation Sites on the β(2)-adrenergic Receptor Establish a Barcode That Encodes Differential Functions of β-arrestin Science Signaling. Aug, 2011 | Pubmed ID: 21868357 A Stress Response Pathway Regulates DNA Damage Through β2-adrenoreceptors and β-arrestin-1 Nature. Sep, 2011 | Pubmed ID: 21857681 Multiple Ligand-specific Conformations of the β2-adrenergic Receptor Nature Chemical Biology. Oct, 2011 | Pubmed ID: 21857662 Quantifying Ligand Bias at Seven-transmembrane Receptors Molecular Pharmacology. Sep, 2011 | Pubmed ID: 21610196 Therapeutic Potential of β-arrestin- and G Protein-biased Agonists Trends in Molecular Medicine. Mar, 2011 | Pubmed ID: 21183406 Global Phosphorylation Analysis of Beta-arrestin-mediated Signaling Downstream of a Seven Transmembrane Receptor (7TMR) Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20686112 Teaching Old Receptors New Tricks: Biasing Seven-transmembrane Receptors Nature Reviews. Drug Discovery. May, 2010 | Pubmed ID: 20431569 Beta-arrestin- but Not G Protein-mediated Signaling by the "decoy" Receptor CXCR7 Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 20018651 Total Chemical Synthesis and Biophysical Characterization of the Minimal Isoform of the KChIP2 Potassium Channel Regulatory Subunit Protein Science : a Publication of the Protein Society. Sep, 2007 | Pubmed ID: 17660260 Visualizing Reaction Pathways in Photoactive Yellow Protein from Nanoseconds to Seconds Proceedings of the National Academy of Sciences of the United States of America. May, 2005 | Pubmed ID: 15870207 A Structural Pathway for Signaling in the E46Q Mutant of Photoactive Yellow Protein Structure (London, England : 1993). Jan, 2005 | Pubmed ID: 15642261 Purification and Initial Characterization of a Putative Blue Light-regulated Phosphodiesterase from Escherichia Coli Photochemistry and Photobiology. Nov-Dec, 2004 | Pubmed ID: 15453820 Analytical Trapping: Extraction of Time-independent Structures from Time-dependent Crystallographic Data Journal of Structural Biology. Sep, 2004 | Pubmed ID: 15450291 Chromophore Conformation and the Evolution of Tertiary Structural Changes in Photoactive Yellow Protein Structure (London, England : 1993). Jun, 2004 | Pubmed ID: 15274923 Analysis of Experimental Time-resolved Crystallographic Data by Singular Value Decomposition Acta Crystallographica. Section D, Biological Crystallography. May, 2004 | Pubmed ID: 15103131 Protein Kinetics: Structures of Intermediates and Reaction Mechanism from Time-resolved X-ray Data Proceedings of the National Academy of Sciences of the United States of America. Apr, 2004 | Pubmed ID: 15041745 Application of Singular Value Decomposition to the Analysis of Time-resolved Macromolecular X-ray Data Biophysical Journal. Mar, 2003 | Pubmed ID: 12609912 Crystal Structure of a Photoactive Yellow Protein from a Sensor Histidine Kinase: Conformational Variability and Signal Transduction Proceedings of the National Academy of Sciences of the United States of America. Feb, 2003 | Pubmed ID: 12563032 The LOV Domain Family: Photoresponsive Signaling Modules Coupled to Diverse Output Domains Biochemistry. Jan, 2003 | Pubmed ID: 12515534 Hemodynamische karakterisatie van diermodellen van pulmonale arteriële hypertensie Zhiyuan Ma1, Lan Mao1, Sudarshan Rajagopal1 1Department of Medicine, Duke University Medical Center Medicina
Hemodynamische karakterisatie van diermodellen van pulmonale arteriële hypertensie Zhiyuan Ma1, Lan Mao1, Sudarshan Rajagopal1 1Department of Medicine, Duke University Medical Center Medicina