Susanne Schiffmann Project Group for Translational Medicine & Pharmacology Fraunhofer IME Biography Publications Institution JoVE Articles Susanne Schiffmann has not added a biography. If you are Susanne Schiffmann and would like to personalize this page please email our Author Liaison for assistance. Publications Alpha-methylacyl-CoA Racemase Deletion Has Mutually Counteracting Effects on T-cell Responses, Associated with Unchanged Course of EAE European Journal of Immunology. Mar, 2016 | Pubmed ID: 26648339 Nanocarriers for Photodynamic Therapy-rational Formulation Design and Medium-scale Manufacture International Journal of Pharmaceutics. Aug, 2015 | Pubmed ID: 26123822 Exacerbation of Experimental Autoimmune Encephalomyelitis in Ceramide Synthase 6 Knockout Mice is Associated with Enhanced Activation/migration of Neutrophils Immunology and Cell Biology. Oct, 2015 | Pubmed ID: 25833068 Lack of Ceramide Synthase 2 Suppresses the Development of Experimental Autoimmune Encephalomyelitis by Impairing the Migratory Capacity of Neutrophils Brain, Behavior, and Immunity. May, 2015 | Pubmed ID: 25697397 Ceramide Synthases CerS4 and CerS5 Are Upregulated by 17β-estradiol and GPER1 Via AP-1 in Human Breast Cancer Cells Biochemical Pharmacology. Dec, 2014 | Pubmed ID: 25451689 Regulation of Ceramide Synthase 6 in a Spontaneous Experimental Autoimmune Encephalomyelitis Model is Sex Dependent Biochemical Pharmacology. Nov, 2014 | Pubmed ID: 25173988 PGE2/EP4 Signaling in Peripheral Immune Cells Promotes Development of Experimental Autoimmune Encephalomyelitis Biochemical Pharmacology. Feb, 2014 | Pubmed ID: 24355567 Ceramide Metabolism in Mouse Tissue The International Journal of Biochemistry & Cell Biology. Aug, 2013 | Pubmed ID: 23792024 The Equilibrium Between Long and Very Long Chain Ceramides is Important for the Fate of the Cell and Can Be Influenced by Co-expression of CerS The International Journal of Biochemistry & Cell Biology. Jul, 2013 | Pubmed ID: 23538298 Ceramide Synthase 6 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis Journal of Immunology (Baltimore, Md. : 1950). Jun, 2012 | Pubmed ID: 22544924 Long Chain Ceramides and Very Long Chain Ceramides Have Opposite Effects on Human Breast and Colon Cancer Cell Growth The International Journal of Biochemistry & Cell Biology. Apr, 2012 | Pubmed ID: 22230369 Chain Length-specific Properties of Ceramides Progress in Lipid Research. Jan, 2012 | Pubmed ID: 22133871 Inhibitors of Specific Ceramide Synthases Biochimie. Feb, 2012 | Pubmed ID: 21945810 Activation of Ceramide Synthase 6 by Celecoxib Leads to a Selective Induction of C16:0-ceramide Biochemical Pharmacology. Dec, 2010 | Pubmed ID: 20735991 Cellular Membranes Function As a Storage Compartment for Celecoxib Journal of Molecular Medicine (Berlin, Germany). Oct, 2009 | Pubmed ID: 19641861 Sphingosine Kinase 2 Deficient Tumor Xenografts Show Impaired Growth and Fail to Polarize Macrophages Towards an Anti-inflammatory Phenotype International Journal of Cancer. Nov, 2009 | Pubmed ID: 19618460 Ceramide Synthases and Ceramide Levels Are Increased in Breast Cancer Tissue Carcinogenesis. May, 2009 | Pubmed ID: 19279183 The Selective COX-2 Inhibitor Celecoxib Modulates Sphingolipid Synthesis Journal of Lipid Research. Jan, 2009 | Pubmed ID: 18711209 The Anti-proliferative Potency of Celecoxib is Not a Class Effect of Coxibs Biochemical Pharmacology. Jul, 2008 | Pubmed ID: 18547544 Dimethylcelecoxib Inhibits Prostaglandin E2 Production Biochemical Pharmacology. Jul, 2008 | Pubmed ID: 18508034 Microarray Analysis of Altered Sphingolipid Metabolism Reveals Prognostic Significance of Sphingosine Kinase 1 in Breast Cancer Breast Cancer Research and Treatment. Nov, 2008 | Pubmed ID: 18058224 P53 is Important for the Anti-proliferative Effect of Ibuprofen in Colon Carcinoma Cells Biochemical and Biophysical Research Communications. Jan, 2008 | Pubmed ID: 18036557 Cyclooxygenase-2 (COX-2)-independent Anticarcinogenic Effects of Selective COX-2 Inhibitors Journal of the National Cancer Institute. Jun, 2006 | Pubmed ID: 16757698 Evidence of COX-2 Independent Induction of Apoptosis and Cell Cycle Block in Human Colon Carcinoma Cells After S- or R-ibuprofen Treatment European Journal of Pharmacology. Jul, 2006 | Pubmed ID: 16730702 In Vivo Release of Non-neuronal Acetylcholine from the Human Skin As Measured by Dermal Microdialysis: Effect of Botulinum Toxin British Journal of Pharmacology. Jan, 2006 | Pubmed ID: 16273117 Metal Sites in 3,4-dihydroxy-2-butanone 4-phosphate Synthase from Methanococcus Jannaschii in Complex with the Substrate Ribulose 5-phosphate Acta Crystallographica. Section D, Biological Crystallography. Jul, 2004 | Pubmed ID: 15213409 Double Chip Protein Arrays Using Recombinant Single-chain Fv Antibody Fragments Proteomics. May, 2004 | Pubmed ID: 15188410 Double-chip Protein Arrays: Force-based Multiplex Sandwich Immunoassays with Increased Specificity Analytical and Bioanalytical Chemistry. Aug, 2004 | Pubmed ID: 15103448 Structure of 3,4-dihydroxy-2-butanone 4-phosphate Synthase from Methanococcus Jannaschii in Complex with Divalent Metal Ions and the Substrate Ribulose 5-phosphate: Implications for the Catalytic Mechanism The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12904291 DNA: a Programmable Force Sensor Science (New York, N.Y.). Jul, 2003 | Pubmed ID: 12869761 Biosynthesis of Riboflavin in Archaea Studies on the Mechanism of 3,4-dihydroxy-2-butanone-4-phosphate Synthase of Methanococcus Jannaschii The Journal of Biological Chemistry. Nov, 2002 | Pubmed ID: 12200440 Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues Julia Barthelmes*1, Nadja Tafferner*2, Jennifer Kurz2, Natasja de Bruin2, Michael J. Parnham2, Gerd Geisslinger1, Susanne Schiffmann2 1Institute of Clinical Pharmacology, Goethe University Hospital Frankfurt, 2Project Group for Translational Medicine & Pharmacology, Fraunhofer IME JoVE 53933 Immunologia e infezioni
Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues Julia Barthelmes*1, Nadja Tafferner*2, Jennifer Kurz2, Natasja de Bruin2, Michael J. Parnham2, Gerd Geisslinger1, Susanne Schiffmann2 1Institute of Clinical Pharmacology, Goethe University Hospital Frankfurt, 2Project Group for Translational Medicine & Pharmacology, Fraunhofer IME JoVE 53933 Immunologia e infezioni