Sven Lang

Publications

• Right Portal Vein Ligation Combined With In Situ Splitting Induces Rapid Left Lateral Liver Lobe Hypertrophy Enabling 2-Staged Extended Right Hepatic Resection in Small-for-Size Settings
  Annals of Surgery. Mar, 2012  |   Pubmed ID: 22330038
• Oncogenic MST1R Activity in Pancreatic and Gastric Cancer Represents a Valid Target of HSP90 Inhibitors
  Anticancer Research. Feb, 2012  |   Pubmed ID: 22287729
• Targeting FGFR/PDGFR/VEGFR Impairs Tumor Growth, Angiogenesis, and Metastasis by Effects on Tumor Cells, Endothelial Cells, and Pericytes in Pancreatic Cancer
  Molecular Cancer Therapeutics. Nov, 2011  |   Pubmed ID: 21885862
• Sec62 Protein Level is Crucial for the ER Stress Tolerance of Prostate Cancer
  The Prostate. Jul, 2011  |   Pubmed ID: 21557272
• Tumor Development in Murine Ulcerative Colitis Depends on MyD88 Signaling of Colonic F4/80+CD11b(high)Gr1(low) Macrophages
  The Journal of Clinical Investigation. May, 2011  |   Pubmed ID: 21519141
• Sec61 Complexes Form Ubiquitous ER Ca2+ Leak Channels
  Channels (Austin, Tex.). May-Jun, 2011  |   Pubmed ID: 21406962
• Transforming Growth Factor-beta 2 Gene Silencing with Trabedersen (AP 12009) in Pancreatic Cancer
  Cancer Science. Jun, 2011  |   Pubmed ID: 21366804
• Sec62 Protein Level is Crucial for the ER Stress Tolerance of Prostate Cancer
  The Prostate. Jan, 2011  |   Pubmed ID: 21229553
• Interaction of Calmodulin with Sec61α Limits Ca2+ Leakage from the Endoplasmic Reticulum
  The EMBO Journal. Jan, 2011  |   Pubmed ID: 21102557
• Activating Transcription Factor-3 (ATF3) Functions As a Tumor Suppressor in Colon Cancer and is Up-regulated Upon Heat-shock Protein 90 (Hsp90) Inhibition
  BMC Cancer. 2010  |   Pubmed ID: 21129190
• Implication of RICTOR in the MTOR Inhibitor-mediated Induction of Insulin-like Growth Factor-I Receptor (IGF-IR) and Human Epidermal Growth Factor Receptor-2 (Her2) Expression in Gastrointestinal Cancer Cells
  Biochimica Et Biophysica Acta. Apr, 2010  |   Pubmed ID: 20116405
• Effect of Heat-shock Protein-90 (HSP90) Inhibition on Human Hepatocytes and on Liver Regeneration in Experimental Models
  Surgery. May, 2010  |   Pubmed ID: 20015528
• Results of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis from Colorectal Cancer
  Journal of Surgical Oncology. Sep, 2009  |   Pubmed ID: 19697436
• Up-regulation of Krüppel-like Factor 5 in Pancreatic Cancer is Promoted by Interleukin-1beta Signaling and Hypoxia-inducible Factor-1alpha
  Molecular Cancer Research : MCR. Aug, 2009  |   Pubmed ID: 19671674
• Lanthanum Ions Inhibit the Mammalian Sec61 Complex in Its Channel Dynamics and Protein Transport Activity
  FEBS Letters. Jul, 2009  |   Pubmed ID: 19555690
• Heat-shock Protein 90 (Hsp90) As a Molecular Target for Therapy of Gastrointestinal Cancer
  Anticancer Research. Jun, 2009  |   Pubmed ID: 19528462
• Targeting Heat-shock Protein 90 Improves Efficacy of Rapamycin in a Model of Hepatocellular Carcinoma in Mice
  Hepatology (Baltimore, Md.). Feb, 2009  |   Pubmed ID: 19085954
• Dual Targeting of Raf and VEGF Receptor 2 Reduces Growth and Metastasis of Pancreatic Cancer Through Direct Effects on Tumor Cells, Endothelial Cells, and Pericytes
  Molecular Cancer Therapeutics. Nov, 2008  |   Pubmed ID: 19001434
• ENMD-1198, a Novel Tubulin-binding Agent Reduces HIF-1alpha and STAT3 Activity in Human Hepatocellular Carcinoma(HCC) Cells, and Inhibits Growth and Vascularization in Vivo
  BMC Cancer. 2008  |   Pubmed ID: 18651980
• Inhibition of Insulin-like Growth Factor-I Receptor (IGF-IR) Using NVP-AEW541, a Small Molecule Kinase Inhibitor, Reduces Orthotopic Pancreatic Cancer Growth and Angiogenesis
  European Journal of Cancer (Oxford, England : 1990). Jul, 2008  |   Pubmed ID: 18445520
• Dual Inhibition of Raf and VEGFR2 Reduces Growth and Vascularization of Hepatocellular Carcinoma in an Experimental Model
  Langenbeck's Archives of Surgery / Deutsche Gesellschaft Für Chirurgie. May, 2008  |   Pubmed ID: 18297306
• Blocking Heat Shock Protein-90 Inhibits the Invasive Properties and Hepatic Growth of Human Colon Cancer Cells and Improves the Efficacy of Oxaliplatin in P53-deficient Colon Cancer Tumors in Vivo
  Molecular Cancer Therapeutics. Nov, 2007  |   Pubmed ID: 18025273
• Targeting Heat Shock Protein 90 in Pancreatic Cancer Impairs Insulin-like Growth Factor-I Receptor Signaling, Disrupts an Interleukin-6/signal-transducer and Activator of Transcription 3/hypoxia-inducible Factor-1alpha Autocrine Loop, and Reduces Orthotopic Tumor Growth
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2007  |   Pubmed ID: 17975158
• The Direct Effects of Anti-vascular Endothelial Growth Factor Therapy on Tumor Cells
  Clinical Colorectal Cancer. Jul, 2007  |   Pubmed ID: 17681102
• Inhibition of Heat Shock Protein 90 Impairs Epidermal Growth Factor-mediated Signaling in Gastric Cancer Cells and Reduces Tumor Growth and Vascularization in Vivo
  Molecular Cancer Therapeutics. Mar, 2007  |   Pubmed ID: 17363505
• Mycophenolate Mofetil Inhibits Tumor Growth and Angiogenesis in Vitro but Has Variable Antitumor Effects in Vivo, Possibly Related to Bioavailability
  Transplantation. Mar, 2007  |   Pubmed ID: 17353782
• Mammalian Target of Rapamycin is Activated in Human Gastric Cancer and Serves As a Target for Therapy in an Experimental Model
  International Journal of Cancer. Journal International Du Cancer. Apr, 2007  |   Pubmed ID: 17230506
• Sirolimus Promotes Tolerance for Donor and Recipient Antigens After MHC Class II Disparate Bone Marrow Transplantation in Rats
  Experimental Hematology. Jan, 2007  |   Pubmed ID: 17198885
• No Contribution of Multipotent Mesenchymal Stromal Cells to Liver Regeneration in a Rat Model of Prolonged Hepatic Injury
  Stem Cells (Dayton, Ohio). Mar, 2007  |   Pubmed ID: 17110617
• CDKN2A Germline Mutations in Familial Pancreatic Cancer
  Annals of Surgery. Dec, 2002  |   Pubmed ID: 12454511
• P16INK4a is a Prognostic Marker in Resected Ductal Pancreatic Cancer: an Analysis of P16INK4a, P53, MDM2, an Rb
  Annals of Surgery. Jan, 2002  |   Pubmed ID: 11753042