Thierry Léveillard Department of Genetics - Sorbonne Université, INSERM, CNRS Institut de la Vision Biography Publications Institution JoVE Articles Thierry Léveillard has not added a biography. If you are Thierry Léveillard and would like to personalize this page please email our Author Liaison for assistance. Publications The Role of RdCVFL in a Mathematical Model of Photoreceptor Interactions Journal of Theoretical Biology. Feb, 2021 | Pubmed ID: 33636201 A Splice Variant in Gene Leads to Lactate Transport Deficit in Human IPS Cell-Derived Retinal Pigment Epithelial Cells Cells. Jan, 2021 | Pubmed ID: 33477551 WDR34, a Candidate Gene for Non-syndromic Rod-cone Dystrophy Clinical Genetics. Feb, 2021 | Pubmed ID: 33124039 Insulin Inhibits Inflammation-induced Cone Death in Retinal Detachment Journal of Neuroinflammation. Nov, 2020 | Pubmed ID: 33243251 The 10q26 Risk Haplotype of Age-Related Macular Degeneration Aggravates Subretinal Inflammation by Impairing Monocyte Elimination Immunity. Aug, 2020 | Pubmed ID: 32814029 Metabolic and Redox Signaling of the Nucleoredoxin-Like-1 Gene for the Treatment of Genetic Retinal Diseases International Journal of Molecular Sciences. Feb, 2020 | Pubmed ID: 32120883 Functional Genomics of the Retina to Elucidate Its Construction and Deconstruction International Journal of Molecular Sciences. Oct, 2019 | Pubmed ID: 31590277 A Mathematical Analysis of Aerobic Glycolysis Triggered by Glucose Uptake in Cones Scientific Reports. 03, 2019 | Pubmed ID: 30858444 Is Retinal Metabolic Dysfunction at the Center of the Pathogenesis of Age-related Macular Degeneration? International Journal of Molecular Sciences. Feb, 2019 | Pubmed ID: 30754662 Mechanisms Underlying the Visual Benefit of Cell Transplantation for the Treatment of Retinal Degenerations International Journal of Molecular Sciences. Jan, 2019 | Pubmed ID: 30696106 Maintaining Cone Function in Rod-Cone Dystrophies Advances in Experimental Medicine and Biology. 2018 | Pubmed ID: 29721982 Otx2-Genetically Modified Retinal Pigment Epithelial Cells Rescue Photoreceptors After Transplantation Molecular Therapy : the Journal of the American Society of Gene Therapy. 01, 2018 | Pubmed ID: 28988713 Cell Signaling with Extracellular Thioredoxin and Thioredoxin-Like Proteins: Insight into Their Mechanisms of Action Oxidative Medicine and Cellular Longevity. 2017 | Pubmed ID: 29138681 Further Insights into the Ciliary Gene and Protein KIZ and Its Murine Ortholog PLK1S1 Mutated in Rod-Cone Dystrophy Genes. Oct, 2017 | Pubmed ID: 29057815 Metabolic and Redox Signaling in the Retina Cellular and Molecular Life Sciences : CMLS. 10, 2017 | Pubmed ID: 27543457 Mathematical Model of the Role of RdCVF in the Coexistence of Rods and Cones in a Healthy Eye Bulletin of Mathematical Biology. 07, 2016 | Pubmed ID: 27444436 The Thioredoxin Encoded by the Rod-Derived Cone Viability Factor Gene Protects Cone Photoreceptors Against Oxidative Stress Antioxidants & Redox Signaling. 06, 2016 | Pubmed ID: 27025156 Identification of an Alternative Splicing Product of the Otx2 Gene Expressed in the Neural Retina and Retinal Pigmented Epithelial Cells PloS One. 2016 | Pubmed ID: 26985665 A Large Genome-wide Association Study of Age-related Macular Degeneration Highlights Contributions of Rare and Common Variants Nature Genetics. Feb, 2016 | Pubmed ID: 26691988 [Altruism in the Retina: Sticks Feed Cones] Medecine Sciences : M/S. Oct, 2015 | Pubmed ID: 26481018 Cancer Metabolism of Cone Photoreceptors Oncotarget. Oct, 2015 | Pubmed ID: 26450906 Genotypic and Phenotypic Characterization of P23H Line 1 Rat Model PloS One. 2015 | Pubmed ID: 26009893 Rod-derived Cone Viability Factor Promotes Cone Survival by Stimulating Aerobic Glycolysis Cell. May, 2015 | Pubmed ID: 25957687 Thioredoxin Rod-derived Cone Viability Factor Protects Against Photooxidative Retinal Damage Free Radical Biology & Medicine. Apr, 2015 | Pubmed ID: 25596499 Viral-mediated RdCVF and RdCVFL Expression Protects Cone and Rod Photoreceptors in Retinal Degeneration The Journal of Clinical Investigation. Jan, 2015 | Pubmed ID: 25415434 Rare and Common Variants in Extracellular Matrix Gene Fibrillin 2 (FBN2) Are Associated with Macular Degeneration Human Molecular Genetics. Nov, 2014 | Pubmed ID: 24899048 Therapeutic Strategy for Handling Inherited Retinal Degenerations in a Gene-independent Manner Using Rod-derived Cone Viability Factors Comptes Rendus Biologies. Mar, 2014 | Pubmed ID: 24702847 Functional Rescue of Cone Photoreceptors in Retinitis Pigmentosa Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Jul, 2013 | Pubmed ID: 23575948 Taurine Provides Neuroprotection Against Retinal Ganglion Cell Degeneration PloS One. 2012 | Pubmed ID: 23115615 Genome-wide Association Study of Age-related Macular Degeneration Identifies Associated Variants in the TNXB-FKBPL-NOTCH4 Region of Chromosome 6p21.3 Human Molecular Genetics. Sep, 2012 | Pubmed ID: 22694956 Nxnl2 Splicing Results in Dual Functions in Neuronal Cell Survival and Maintenance of Cell Integrity Human Molecular Genetics. May, 2012 | Pubmed ID: 22343139 Intero-exome Sequenziamento Identifica Mutazioni GPR179 Che Autosomica Recessiva Completa Cecità Congenita Notturna Stazionaria American Journal of Human Genetics. Feb, 2012 | Pubmed ID: 22325361 Development and Application of a Next-generation-sequencing (NGS) Approach to Detect Known and Novel Gene Defects Underlying Retinal Diseases Orphanet Journal of Rare Diseases. 2012 | Pubmed ID: 22277662 Complemento Fattore H Variante Genetica E La Degenerazione Maculare Legata All'età: Effetto Dimensione, Modificatori E Relazione Di Sottotipo Di Malattia International Journal of Epidemiology. Jan, 2012 | Pubmed ID: 22253316 CRB1 Mutations in Inherited Retinal Dystrophies Human Mutation. Feb, 2012 | Pubmed ID: 22065545 ℮-conome: an Automated Tissue Counting Platform of Cone Photoreceptors for Rodent Models of Retinitis Pigmentosa BMC Ophthalmology. 2011 | Pubmed ID: 22185426 Transcriptomic Analysis of Human Retinal Detachment Reveals Both Inflammatory Response and Photoreceptor Death PloS One. 2011 | Pubmed ID: 22174898 Quality Control of Citri Reticulatae Pericarpium: Exploratory Analysis and Discrimination Analytica Chimica Acta. Oct, 2011 | Pubmed ID: 21962354 The Respiratory-dependent Assembly of ANT1 Differentially Regulates Bax and Ca2+ Mediated Cytochrome C Release Frontiers in Bioscience (Elite Edition). 2011 | Pubmed ID: 21196320 Transplantation of Photoreceptor and Total Neural Retina Preserves Cone Function in P23H Rhodopsin Transgenic Rat PloS One. 2010 | Pubmed ID: 20976047 Expression of Rod-derived Cone Viability Factor: Dual Role of CRX in Regulating Promoter Activity and Cell-type Specificity PloS One. 2010 | Pubmed ID: 20949100 Rod-derived Cone Viability Factor for Treating Blinding Diseases: from Clinic to Redox Signaling Science Translational Medicine. Apr, 2010 | Pubmed ID: 20375363 The Homeobox Gene CHX10/VSX2 Regulates RdCVF Promoter Activity in the Inner Retina Human Molecular Genetics. Jan, 2010 | Pubmed ID: 19843539 TRPM1 is Mutated in Patients with Autosomal-recessive Complete Congenital Stationary Night Blindness American Journal of Human Genetics. Nov, 2009 | Pubmed ID: 19896113 [Hydration of Patients Treated with Cisplatin: Practical Investigation and Establishment of a Protocol] Thérapie. Sep-Oct, 2005 | Pubmed ID: 16433016 Collagen Types XII and XIV Are Present in Basement Membrane Zones During Human Embryonic Development Journal of Molecular Histology. Nov, 2004 | Pubmed ID: 15609093 Culture arricchite di coni dalla retina degli embrioni di pollo per studiare le interazioni cellulari tra bastone e cono Géraldine Millet-Puel1, Myriam Pinault1, Marie Cordonnier1, Valérie Fontaine1, José-Alain Sahel1, Thierry Léveillard1 1Department of Genetics - Sorbonne Université, INSERM, CNRS, Institut de la Vision JoVE 61998 Neuroscienze Vibratome sezionamento mouse Retina preparare Culture fotorecettori Emmanuelle Clérin1,4,5,6, Ying Yang1,4,5,6, Valérie Forster2,4,5,6, Valérie Fontaine3,4,5,6, José-Alain Sahel4,5,6, Thierry Léveillard1,4,5,6 1Department of Genetics, UMR_S 968, Institut de la Vision, 2Department of Visual Information, UMR_S 968, Institut de la Vision, 3Exploratory Team, UMR_S 968, Institut de la Vision, 4Sorbonne Universités, Paris 06, UMR_S 968, Institut de la Vision, 5INSERM, U968, Institut de la Vision, 6CNRS, UMR_7210, Institut de la Vision JoVE 51954 Neuroscienze Analisi trascrittomica di campioni chirurgici retiniche umane Utilizzo ufficiale Marie-Noëlle Delyfer1,2,3,4, Najate Aït-Ali1,2,3, Hawa Camara1,2,3, Emmanuelle Clérin1,2,3, Jean-François Korobelnik4, José-Alain Sahel1,2,3, Thierry Léveillard1,2,3 1U968, Institut National de la Santé et de la Recherche Médicale, 2UMR S 968, Université Pierre et Marie Curie, 3UMR 7210, Centre National de la Recherche Scientifique, 4Départment d'Ophtalmologie, Centre Hospitalier Universitaire de Bordeaux JoVE 50375 Medicina
Culture arricchite di coni dalla retina degli embrioni di pollo per studiare le interazioni cellulari tra bastone e cono Géraldine Millet-Puel1, Myriam Pinault1, Marie Cordonnier1, Valérie Fontaine1, José-Alain Sahel1, Thierry Léveillard1 1Department of Genetics - Sorbonne Université, INSERM, CNRS, Institut de la Vision JoVE 61998 Neuroscienze
Vibratome sezionamento mouse Retina preparare Culture fotorecettori Emmanuelle Clérin1,4,5,6, Ying Yang1,4,5,6, Valérie Forster2,4,5,6, Valérie Fontaine3,4,5,6, José-Alain Sahel4,5,6, Thierry Léveillard1,4,5,6 1Department of Genetics, UMR_S 968, Institut de la Vision, 2Department of Visual Information, UMR_S 968, Institut de la Vision, 3Exploratory Team, UMR_S 968, Institut de la Vision, 4Sorbonne Universités, Paris 06, UMR_S 968, Institut de la Vision, 5INSERM, U968, Institut de la Vision, 6CNRS, UMR_7210, Institut de la Vision JoVE 51954 Neuroscienze
Analisi trascrittomica di campioni chirurgici retiniche umane Utilizzo ufficiale Marie-Noëlle Delyfer1,2,3,4, Najate Aït-Ali1,2,3, Hawa Camara1,2,3, Emmanuelle Clérin1,2,3, Jean-François Korobelnik4, José-Alain Sahel1,2,3, Thierry Léveillard1,2,3 1U968, Institut National de la Santé et de la Recherche Médicale, 2UMR S 968, Université Pierre et Marie Curie, 3UMR 7210, Centre National de la Recherche Scientifique, 4Départment d'Ophtalmologie, Centre Hospitalier Universitaire de Bordeaux JoVE 50375 Medicina