Timo L.M. ten Hagen Laboratory Experimental Surgical Oncology, Section Surgical Oncology, Department of Surgery Erasmus MC Biography Publications Institution JoVE Articles Timo L.M. ten Hagen has not added a biography. If you are Timo L.M. ten Hagen and would like to personalize this page please email our Author Liaison for assistance. Publications Inhomogeneous Crystal Grain Formation in DPPC-DSPC Based Thermosensitive Liposomes Determines Content Release Kinetics Journal of Controlled Release : Official Journal of the Controlled Release Society. Feb, 2017 | Pubmed ID: 28042084 High-Resolution Intravital Microscopy of Tumor Angiogenesis Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 27858361 Melanomas Prevent Endothelial Cell Death Under Restrictive Culture Conditions by Signaling Through AKT and P38 MAPK/ ERK-1/2 Cascades Oncoimmunology. 2016 | Pubmed ID: 27853641 Lipid Phosphatase SHIP2 Functions As Oncogene in Colorectal Cancer by Regulating PKB Activation Oncotarget. Nov, 2016 | Pubmed ID: 27716613 Investigation of Particle Accumulation, Chemosensitivity and Thermosensitivity for Effective Solid Tumor Therapy Using Thermosensitive Liposomes and Hyperthermia Theranostics. 2016 | Pubmed ID: 27446503 EGFR Targeted Thermosensitive Liposomes: A Novel Multifunctional Platform for Simultaneous Tumor Targeted and Stimulus Responsive Drug Delivery Colloids and Surfaces. B, Biointerfaces. Oct, 2016 | Pubmed ID: 27434152 Targeting Melanoma with Immunoliposomes Coupled to Anti-MAGE A1 TCR-like Single-chain Antibody International Journal of Nanomedicine. 2016 | Pubmed ID: 27022262 Increased PTP1B Expression and Phosphatase Activity in Colorectal Cancer Results in a More Invasive Phenotype and Worse Patient Outcome Oncotarget. Apr, 2016 | Pubmed ID: 26942883 Light Fractionation Significantly Increases the Efficacy of Photodynamic Therapy Using BF-200 ALA in Normal Mouse Skin PloS One. 2016 | Pubmed ID: 26872051 Association of TIMP3 Expression with Vessel Density, Macrophage Infiltration and Prognosis in Human Malignant Melanoma European Journal of Cancer (Oxford, England : 1990). Jan, 2016 | Pubmed ID: 26707830 Pharmacokinetics, Tissue Distribution and Therapeutic Effect of Cationic Thermosensitive Liposomal Doxorubicin Upon Mild Hyperthermia Pharmaceutical Research. Mar, 2016 | Pubmed ID: 26518763 Formulation and Optimization of Idarubicin Thermosensitive Liposomes Provides Ultrafast Triggered Release at Mild Hyperthermia and Improves Tumor Response Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2015 | Pubmed ID: 26541464 Development of a Novel Cyclic RGD Peptide for Multiple Targeting Approaches of Liposomes to Tumor Region Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2015 | Pubmed ID: 26526970 Enhanced Specificity and Drug Delivery in Tumors by CRGD-Anchoring Thermosensitive Liposomes Pharmaceutical Research. Dec, 2015 | Pubmed ID: 26202516 Cetuximab-oxaliplatin-liposomes for Epidermal Growth Factor Receptor Targeted Chemotherapy of Colorectal Cancer Journal of Controlled Release : Official Journal of the Controlled Release Society. Jul, 2015 | Pubmed ID: 25998052 Plasma Membrane Targeting by Short Chain Sphingolipids Inserted in Liposomes Improves Anti-tumor Activity of Mitoxantrone in an Orthotopic Breast Carcinoma Xenograft Model European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Aug, 2015 | Pubmed ID: 25982691 C8-glycosphingolipids Preferentially Insert into Tumor Cell Membranes and Promote Chemotherapeutic Drug Uptake Biochimica Et Biophysica Acta. Aug, 2015 | Pubmed ID: 25917957 Low Molecular Weight Protein Tyrosine Phosphatase (LMWPTP) Upregulation Mediates Malignant Potential in Colorectal Cancer Oncotarget. Apr, 2015 | Pubmed ID: 25811796 Short-chain Glycoceramides Promote Intracellular Mitoxantrone Delivery from Novel Nanoliposomes into Breast Cancer Cells Pharmaceutical Research. Apr, 2015 | Pubmed ID: 25319103 Targeted and Heat-triggered Doxorubicin Delivery to Tumors by Dual Targeted Cationic Thermosensitive Liposomes Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2014 | Pubmed ID: 25176578 Somatostatin Analogues for Receptor Targeted Photodynamic Therapy PloS One. 2014 | Pubmed ID: 25111655 [(111)In-DTPA]octreotide Tumor Uptake in GEPNET Liver Metastases After Intra-arterial Administration: an Overview of Preclinical and Clinical Observations and Implications for Tumor Radiation Dose After Peptide Radionuclide Therapy Cancer Biotherapy & Radiopharmaceuticals. May, 2014 | Pubmed ID: 24820805 Exposing Endothelial Cells to Tumor Necrosis Factor-α and Peripheral Blood Mononuclear Cells Damage Endothelial Integrity Via Interleukin-1ß by Degradation of Vascular Endothelial-cadherin Surgery. Mar, 2014 | Pubmed ID: 24439748 Intact Doxil is Taken Up Intracellularly and Released Doxorubicin Sequesters in the Lysosome: Evaluated by in Vitro/in Vivo Live Cell Imaging Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2013 | Pubmed ID: 24012486 The αVβ3/αVβ5 Integrin Inhibitor Cilengitide Augments Tumor Response to Melphalan Isolated Limb Perfusion in a Sarcoma Model International Journal of Cancer. Jun, 2013 | Pubmed ID: 23152080 Multimodality Imaging of Somatostatin Receptor-positive Tumors with Nuclear and Bioluminescence Imaging Molecular Imaging. Feb, 2012 | Pubmed ID: 22418025 Changes of Ferritin and CRP Levels in Melanoma Patients Treated with Adjuvant Interferon-α (EORTC 18952) and Prognostic Value on Treatment Outcome Melanoma Research. Aug, 2011 | Pubmed ID: 21546857 Local ATP Generation by Brain-type Creatine Kinase (CK-B) Facilitates Cell Motility PloS One. 2009 | Pubmed ID: 19333390 Laboratory Models of Regional Chemotherapy International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. May, 2008 | Pubmed ID: 18393006 Tumor Necrosis Factor-mediated Interactions Between Inflammatory Response and Tumor Vascular Bed Immunological Reviews. Apr, 2008 | Pubmed ID: 18364010 TNF and Manipulation of the Tumor Cell-stromal Interface: "ways to Make Chemotherapy Effective" Frontiers in Bioscience : a Journal and Virtual Library. Jan, 2008 | Pubmed ID: 17981776 Tumor Necrosis Factor Alpha Mediates Homogeneous Distribution of Liposomes in Murine Melanoma That Contributes to a Better Tumor Response Cancer Research. Oct, 2007 | Pubmed ID: 17909055 Vasoactive Peptides Upregulate MRNA Expression and Secretion of Vascular Endothelial Growth Factor in Human Airway Smooth Muscle Cells Cell Biochemistry and Biophysics. 2007 | Pubmed ID: 17406064 Synergistic Antitumor Effects of Histamine Plus Melphalan in Isolated Hepatic Perfusion for Liver Metastases Annals of Surgical Oncology. Feb, 2007 | Pubmed ID: 17096052 Decreased Response Rates by the Combination of Histamine and IL-2 in Melphalan-based Isolated Limb Perfusion Cancer Immunology, Immunotherapy : CII. Apr, 2007 | Pubmed ID: 16896966 EMAP-II Facilitates TNF-R1 Apoptotic Signalling in Endothelial Cells and Induces TRADD Mobilization Apoptosis : an International Journal on Programmed Cell Death. Dec, 2006 | Pubmed ID: 17051333 Early Destruction of Tumor Vasculature in Tumor Necrosis Factor-alpha-based Isolated Limb Perfusion is Responsible for Tumor Response Anti-cancer Drugs. Sep, 2006 | Pubmed ID: 16940805 Differential Effects of Matrix and Growth Factors on Endothelial and Fibroblast Motility: Application of a Modified Cell Migration Assay Journal of Cellular Biochemistry. Dec, 2006 | Pubmed ID: 16817234 Changing the Pathophysiology of Solid Tumours: the Potential of TNF and Other Vasoactive Agents International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. May, 2006 | Pubmed ID: 16754345 Intratumoural Expression of TNF-R1 and EMAP-II in Relation to Response of Patients Treated with TNF-based Isolated Limb Perfusion International Journal of Cancer. Sep, 2006 | Pubmed ID: 16615114 TNF-alpha in Cancer Treatment: Molecular Insights, Antitumor Effects, and Clinical Utility The Oncologist. Apr, 2006 | Pubmed ID: 16614236 Technology Insight: Utility of TNF-alpha-based Isolated Limb Perfusion to Avoid Amputation of Irresectable Tumors of the Extremities Nature Clinical Practice. Oncology. Feb, 2006 | Pubmed ID: 16462850 MR Angiography of Tumor-related Vasculature: from the Clinic to the Micro-environment Radiographics : a Review Publication of the Radiological Society of North America, Inc. Oct, 2005 | Pubmed ID: 16227499 Histamine Combined with Melphalan in Isolated Limb Perfusion for the Treatment of Locally Advanced Soft Tissue Sarcomas: Preclinical Studies in Rats Acta Cirurgica Brasileira. Jul-Aug, 2005 | Pubmed ID: 16186945 Addition of Low-dose Tumor Necrosis Factor-alpha to Systemic Treatment with STEALTH Liposomal Doxorubicin (Doxil) Improved Anti-tumor Activity in Osteosarcoma-bearing Rats Anti-cancer Drugs. Jul, 2005 | Pubmed ID: 15930896 Synergistic Antitumor Response of Interleukin 2 with Melphalan in Isolated Limb Perfusion in Soft Tissue Sarcoma-bearing Rats Cancer Research. May, 2005 | Pubmed ID: 15899822 Effect of Low-dose Tumor Necrosis Factor-alpha in Combination with STEALTH Liposomal Cisplatin (SPI-077) on Soft-tissue- and Osteosarcoma-bearing Rats Anticancer Research. Mar-Apr, 2005 | Pubmed ID: 15868905 Synergistic Antitumor Activity of Histamine Plus Melphalan in Isolated Limb Perfusion: Preclinical Studies Journal of the National Cancer Institute. Nov, 2004 | Pubmed ID: 15523089 Lack of Efficacy of Doxil in TNF-alpha-based Isolated Limb Perfusion in Sarcoma-bearing Rats British Journal of Cancer. May, 2004 | Pubmed ID: 15208623 Solid Tumor Therapy: Manipulation of the Vasculature with TNF Technology in Cancer Research & Treatment. Jun, 2003 | Pubmed ID: 12779350 La microscopie intravitale du système vasculaire associées à la tumeur en utilisant Advanced dorsale pli fenêtre Chambers sur des souris transgéniques fluorescents Ann L.B. Seynhaeve1, Timo L.M. ten Hagen1 1Laboratory Experimental Surgical Oncology, Section Surgical Oncology, Department of Surgery, Erasmus MC JoVE 55115 Medicina À l’aide de In Vitro imagerie de cellules vivantes pour explorer les agents chimiothérapeutiques livré par nanoparticules à base de lipides Ann L.B. Seynhaeve1, Timo L.M. ten Hagen1 1Laboratory Experimental Surgical Oncology, Section Surgical Oncology, Department of Surgery, Erasmus MC JoVE 55405 Medicina
La microscopie intravitale du système vasculaire associées à la tumeur en utilisant Advanced dorsale pli fenêtre Chambers sur des souris transgéniques fluorescents Ann L.B. Seynhaeve1, Timo L.M. ten Hagen1 1Laboratory Experimental Surgical Oncology, Section Surgical Oncology, Department of Surgery, Erasmus MC JoVE 55115 Medicina
À l’aide de In Vitro imagerie de cellules vivantes pour explorer les agents chimiothérapeutiques livré par nanoparticules à base de lipides Ann L.B. Seynhaeve1, Timo L.M. ten Hagen1 1Laboratory Experimental Surgical Oncology, Section Surgical Oncology, Department of Surgery, Erasmus MC JoVE 55405 Medicina