Todd McKinley Department of Anatomy, Cell Biology and Physiology Indiana University School of Medicine Biography Publications Institution JoVE Articles Todd McKinley has not added a biography. If you are Todd McKinley and would like to personalize this page please email our Author Liaison for assistance. Publications In Situ Forming Biomaterials As Muscle Void Fillers for the Provisional Treatment of Volumetric Muscle Loss Injuries Materials Today. Bio. Oct, 2023 | Pubmed ID: 37736246 Work Productivity Loss After Minimally Displaced Complete Lateral Compression Pelvis Fractures Journal of Orthopaedic Trauma. Aug, 2023 | Pubmed ID: 37653607 Post-traumatic Osteoarthritis: A Review of Pathogenic Mechanisms and Novel Targets for Mitigation Bone Reports. Jun, 2023 | Pubmed ID: 37425196 Minced Muscle Autografting Improves Bone Healing but Not Muscle Function in a Porcine Composite Injury Model Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Sep, 2023 | Pubmed ID: 36924069 CAMKK2 is Upregulated in Primary Human Osteoarthritis and Its Inhibition Protects Against Chondrocyte Apoptosis Osteoarthritis and Cartilage. Jul, 2023 | Pubmed ID: 36858195 Reliability of the Modified Radiographic Union Score for Tibia Fractures (mRUST) for Femoral Shaft Fractures Journal of Orthopaedic Trauma. Apr, 2023 | Pubmed ID: 36727993 Application of Bayesian Methods to Help Interpret the VANCO Trial Results Journal of Orthopaedic Trauma. Jan, 2023 | Pubmed ID: 35830572 Bone Morphogenetic Protein-2 Rapidly Heals Two Distinct Critical Sized Segmental Diaphyseal Bone Defects in a Porcine Model Military Medicine. Jan, 2023 | Pubmed ID: 34557897 Risk Factors for Complications Within 30 Days of Operatively Fixed Periprosthetic Femur Fractures Journal of Clinical Orthopaedics and Trauma. Aug, 2022 | Pubmed ID: 35799883 Long-Term Consequences of Major Extremity Trauma: A Pilot Study Journal of Orthopaedic Trauma. Jan, 2022 | Pubmed ID: 34924515 Patient-Specific Precision Injury Signatures to Optimize Orthopaedic Interventions in Multiply Injured Patients (PRECISE STUDY) Journal of Orthopaedic Trauma. Jan, 2022 | Pubmed ID: 34924514 Single-cell RNA Sequencing of Intramedullary Canal Tissue to Improve Methods for Studying Fracture Repair Biology BioTechniques. Aug, 2021 | Pubmed ID: 34374302 Polytraumatized Patient Lower Extremity Nonunion Development: Raw Data Data in Brief. Aug, 2021 | Pubmed ID: 34258338 Divergence of Military and Civilian Trauma Research Priorities Trauma Surgery & Acute Care Open. 2021 | Pubmed ID: 34212117 Base Deficit ≥ 6 Within 24 h of Injury is a Risk Factor for Fracture Nonunion in the Polytraumatized Patient Injury. Nov, 2021 | Pubmed ID: 34053772 A Prospective Clinical Trial Comparing Surgical Fixation Versus Nonoperative Management of Minimally Displaced Complete Lateral Compression Pelvis Fractures Journal of Orthopaedic Trauma. Nov, 2021 | Pubmed ID: 33993178 Polytrauma: Update on Basic Science and Clinical Evidence OTA International : the Open Access Journal of Orthopaedic Trauma. Mar, 2021 | Pubmed ID: 33937720 The Use of Multiplexing to Identify Cytokine and Chemokine Networks in the Immune-Inflammatory Response to Trauma Antioxidants & Redox Signaling. Dec, 2021 | Pubmed ID: 33860683 Protective/reparative Cytokines Are Suppressed at High Injury Severity in Human Trauma Trauma Surgery & Acute Care Open. 2021 | Pubmed ID: 33748428 A Modified Levine Approach for Exposure of the Anterior Column, Anterior Wall, and Sacroiliac Joint: A Surgical Technique and a Case Series Journal of Orthopaedic Trauma. Dec, 2021 | Pubmed ID: 33724966 Internal Fixation Construct and Defect Size Affect Healing of a Translational Porcine Diaphyseal Tibial Segmental Bone Defect Military Medicine. Nov, 2021 | Pubmed ID: 33242094 Early Dynamic Orchestration of Immunologic Mediators Identifies Multiply Injured Patients Who Are Tolerant or Sensitive to Hemorrhage The Journal of Trauma and Acute Care Surgery. Mar, 2021 | Pubmed ID: 33093290 Predictors of Improved Early Clinical Outcomes After Elective Implant Removal Journal of Orthopaedic Trauma. Mar, 2021 | Pubmed ID: 33079840 Incidence and Clinical Impact of Lower Extremity Vascular Injuries in the Setting of Whole Body Computed Tomography for Trauma Emergency Radiology. Apr, 2021 | Pubmed ID: 32857232 Insights into the Association Between Coagulopathy and Inflammation: Abnormal Clot Mechanics Are a Warning of Immunologic Dysregulation Following Major Injury Annals of Translational Medicine. Dec, 2020 | Pubmed ID: 33437775 A Comprehensive Review of Mouse Diaphyseal Femur Fracture Models Injury. Jul, 2020 | Pubmed ID: 32362447 Dysfunctional Stem and Progenitor Cells Impair Fracture Healing with Age World Journal of Stem Cells. Jun, 2019 | Pubmed ID: 31293713 Computational Evidence for an Early, Amplified Systemic Inflammation Program in Polytrauma Patients with Severe Extremity Injuries PloS One. 2019 | Pubmed ID: 31163056 Precision Medicine Applications to Manage Multiply Injured Patients With Orthopaedic Trauma Journal of Orthopaedic Trauma. Jun, 2019 | Pubmed ID: 31083145 Early Immunologic Response in Multiply Injured Patients With Orthopaedic Injuries Is Associated With Organ Dysfunction Journal of Orthopaedic Trauma. May, 2019 | Pubmed ID: 31008819 Blood Purification by Nonselective Hemoadsorption Prevents Death After Traumatic Brain Injury and Hemorrhagic Shock in Rats The Journal of Trauma and Acute Care Surgery. Dec, 2018 | Pubmed ID: 30211852 Costs and Radiographic Outcomes of Rotational Ankle Fractures Treated by Orthopaedic Surgeons With or Without Trauma Fellowship Training The Journal of the American Academy of Orthopaedic Surgeons. Jun, 2018 | Pubmed ID: 29787464 Development of a Step-down Method for Altering Male C57BL/6 Mouse Housing Density and Hierarchical Structure: Preparations for Spaceflight Studies Life Sciences in Space Research. May, 2018 | Pubmed ID: 29753413 Shock Volume: Patient-specific Cumulative Hypoperfusion Predicts Organ Dysfunction in a Prospective Cohort of Multiply Injured Patients The Journal of Trauma and Acute Care Surgery. Jul, 2018 | Pubmed ID: 29521799 Forces Associated with Launch into Space Do Not Impact Bone Fracture Healing Life Sciences in Space Research. Feb, 2018 | Pubmed ID: 29475520 Management of Mangled Extremities and Orthopaedic War Injuries Journal of Orthopaedic Trauma. Mar, 2018 | Pubmed ID: 29461402 Diagnosis and Management of Polytraumatized Patients With Severe Extremity Trauma Journal of Orthopaedic Trauma. Mar, 2018 | Pubmed ID: 29461394 Autologous Minced Muscle Grafts Improve Endogenous Fracture Healing and Muscle Strength After Musculoskeletal Trauma Physiological Reports. Jul, 2017 | Pubmed ID: 28747511 Impairment of Early Fracture Healing by Skeletal Muscle Trauma is Restored by FK506 BMC Musculoskeletal Disorders. Jun, 2017 | Pubmed ID: 28606129 Electroacupuncture Promotes Central Nervous System-Dependent Release of Mesenchymal Stem Cells Stem Cells (Dayton, Ohio). May, 2017 | Pubmed ID: 28299842 Fractures of the Tibial Plateau Involve Similar Energies As the Tibial Pilon but Greater Articular Surface Involvement Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Mar, 2017 | Pubmed ID: 27381653 Objective Metric of Energy Absorbed in Tibial Plateau Fractures Corresponds Well to Clinician Assessment of Fracture Severity Journal of Orthopaedic Trauma. Oct, 2016 | Pubmed ID: 27243347 Tissue Damage Volume Predicts Organ Dysfunction and Inflammation After Injury The Journal of Surgical Research. May, 2016 | Pubmed ID: 27083966 Large-magnitude Pelvic and Retroperitoneal Tissue Damage Predicts Organ Failure Clinical Orthopaedics and Related Research. Jun, 2016 | Pubmed ID: 26762300 SHOCK VOLUME: A PATIENT-SPECIFIC INDEX THAT PREDICTS TRANSFUSION REQUIREMENTS AND ORGAN DYSFUNCTION IN MULTIPLY INJURED PATIENTS Shock (Augusta, Ga.). Feb, 2016 | Pubmed ID: 26529663 The Effect of PH Versus Base Deficit on Organ Failure in Trauma Patients The Journal of Surgical Research. Jan, 2016 | Pubmed ID: 26233689 A Reproducible Cartilage Impact Model to Generate Post-Traumatic Osteoarthritis in the Rabbit Julian Dilley*1,2,3, Hessam Noori-Dokht*3,4,6, Abhijit Seetharam1, Margaret Bello1,3, Aaron Nanavaty1,3, Roman M. Natoli2,3, Todd McKinley1,2,3, Zachary Bault5, Diane Wagner2,3,6, Uma Sankar1,3 1Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, 2Department of Orthopaedic Surgery, Indiana University School of Medicine, 3Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, 4School of Mechanical Engineering, Purdue University, 5Large Animal Resource Center, Indiana University School of Medicine, 6Department of Mechanical and Energy Engineering, Indiana University-Purdue University Indianapolis JoVE 64450 Medicina
A Reproducible Cartilage Impact Model to Generate Post-Traumatic Osteoarthritis in the Rabbit Julian Dilley*1,2,3, Hessam Noori-Dokht*3,4,6, Abhijit Seetharam1, Margaret Bello1,3, Aaron Nanavaty1,3, Roman M. Natoli2,3, Todd McKinley1,2,3, Zachary Bault5, Diane Wagner2,3,6, Uma Sankar1,3 1Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, 2Department of Orthopaedic Surgery, Indiana University School of Medicine, 3Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, 4School of Mechanical Engineering, Purdue University, 5Large Animal Resource Center, Indiana University School of Medicine, 6Department of Mechanical and Energy Engineering, Indiana University-Purdue University Indianapolis JoVE 64450 Medicina