Wing-Kee Lee Institute for Physiology, Pathophysiology, & Toxicology, Centre for Biomedical Research and Training (ZBAF) University of Witten/Herdecke Biography Publications Institution JoVE Articles Wing-Kee Lee has not added a biography. If you are Wing-Kee Lee and would like to personalize this page please email our Author Liaison for assistance. Publications Dynamic Changes in Saliva After Acute Mental Stress Scientific Reports. 2014 | Pubmed ID: 24811301 Differential Transcytosis and Toxicity of the HNGAL Receptor Ligands Cadmium-metallothionein and Cadmium-phytochelatin in Colon-like Caco-2 Cells: Implications for in Vivo Cadmium Toxicity Toxicology Letters. Apr, 2014 | Pubmed ID: 24518829 Nickel-induced Cell Death and Survival Pathways in Cultured Renal Proximal Tubule Cells: Roles of Reactive Oxygen Species, Ceramide and ABCB1 Archives of Toxicology. Apr, 2014 | Pubmed ID: 24448832 Cadmium and Cellular Signaling Cascades: Interactions Between Cell Death and Survival Pathways Archives of Toxicology. Oct, 2013 | Pubmed ID: 23982889 Substrate- and Cell Contact-dependent Inhibitor Affinity of Human Organic Cation Transporter 2: Studies with Two Classical Organic Cation Substrates and the Novel Substrate Cd2+ Molecular Pharmaceutics. Aug, 2013 | Pubmed ID: 23763587 Toxicology of Cadmium and Its Damage to Mammalian Organs Metal Ions in Life Sciences. 2013 | Pubmed ID: 23430781 Pituitary Homeobox 2 (PITX2) Protects Renal Cancer Cell Lines Against Doxorubicin Toxicity by Transcriptional Activation of the Multidrug Transporter ABCB1 International Journal of Cancer. Journal International Du Cancer. Aug, 2013 | Pubmed ID: 23354914 Acute Short-term Mental Stress Does Not Influence Salivary Flow Rate Dynamics PloS One. 2012 | Pubmed ID: 23272098 ERK1/2-dependent Bestrophin-3 Expression Prevents ER-stress-induced Cell Death in Renal Epithelial Cells by Reducing CHOP Biochimica Et Biophysica Acta. Oct, 2012 | Pubmed ID: 22705154 Cyclosporin A, but Not FK506, Induces Osmotic Lysis of Pancreas Zymogen Granules, Intra-acinar Enzyme Release, and Lysosome Instability by Activating K+ Channel Pancreas. May, 2012 | Pubmed ID: 22158076 Lipocalin-2 (24p3/neutrophil Gelatinase-associated Lipocalin (NGAL)) Receptor is Expressed in Distal Nephron and Mediates Protein Endocytosis The Journal of Biological Chemistry. Jan, 2012 | Pubmed ID: 22084236 ABCB1 Protects Kidney Proximal Tubule Cells Against Cadmium-induced Apoptosis: Roles of Cadmium and Ceramide Transport Toxicological Sciences : an Official Journal of the Society of Toxicology. Jun, 2011 | Pubmed ID: 21436125 Role of Arf1 in Endosomal Trafficking of Protein-metal Complexes and Cadmium-metallothionein-1 Toxicity in Kidney Proximal Tubule Cells Toxicology Letters. Jun, 2011 | Pubmed ID: 21421027 Ferroportin 1 is Expressed Basolaterally in Rat Kidney Proximal Tubule Cells and Iron Excess Increases Its Membrane Trafficking Journal of Cellular and Molecular Medicine. Feb, 2011 | Pubmed ID: 20015204 Cadmium Induces Wnt Signaling to Upregulate Proliferation and Survival Genes in Sub-confluent Kidney Proximal Tubule Cells Molecular Cancer. 2010 | Pubmed ID: 20459685 Cadmium-induced DNA Damage Triggers G(2)/M Arrest Via Chk1/2 and Cdc2 in P53-deficient Kidney Proximal Tubule Cells American Journal of Physiology. Renal Physiology. Feb, 2010 | Pubmed ID: 19923412 Organic Cation Transporters: Physiology, Toxicology and Special Focus on Ethidium As a Novel Substrate Current Drug Metabolism. Jul, 2009 | Pubmed ID: 19702534 Organic Cation Transporters OCT1, 2, and 3 Mediate High-affinity Transport of the Mutagenic Vital Dye Ethidium in the Kidney Proximal Tubule American Journal of Physiology. Renal Physiology. Jun, 2009 | Pubmed ID: 19357179 Novel Roles for Ceramides, Calpains and Caspases in Kidney Proximal Tubule Cell Apoptosis: Lessons from in Vitro Cadmium Toxicity Studies Biochemical Pharmacology. Dec, 2008 | Pubmed ID: 18675256 Role of ARF6 in Internalization of Metal-binding Proteins, Metallothionein and Transferrin, and Cadmium-metallothionein Toxicity in Kidney Proximal Tubule Cells Toxicology and Applied Pharmacology. Jul, 2008 | Pubmed ID: 18353411 Evidence for KCNQ1 K+ Channel Expression in Rat Zymogen Granule Membranes and Involvement in Cholecystokinin-induced Pancreatic Acinar Secretion American Journal of Physiology. Cell Physiology. Apr, 2008 | Pubmed ID: 18216164 Knockdown of Endosomal/lysosomal Divalent Metal Transporter 1 by RNA Interference Prevents Cadmium-metallothionein-1 Cytotoxicity in Renal Proximal Tubule Cells American Journal of Physiology. Renal Physiology. Sep, 2007 | Pubmed ID: 17596526 Cadmium-induced Ceramide Formation Triggers Calpain-dependent Apoptosis in Cultured Kidney Proximal Tubule Cells American Journal of Physiology. Cell Physiology. Sep, 2007 | Pubmed ID: 17596294 Cadmium Induces Nuclear Translocation of Beta-catenin and Increases Expression of C-myc and Abcb1a in Kidney Proximal Tubule Cells Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine. Oct, 2007 | Pubmed ID: 17136310 AC Electric Field Assisted Photo-induced High Efficiency Orientational Diffractive Grating in Nematic Liquid Crystals Optics Express. Mar, 2006 | Pubmed ID: 19503554 A Role for Mitochondrial Aquaporins in Cellular Life-and-death Decisions? American Journal of Physiology. Cell Physiology. Aug, 2006 | Pubmed ID: 16624989 Caspase-dependent and -independent Pathways for Cadmium-induced Apoptosis in Cultured Kidney Proximal Tubule Cells American Journal of Physiology. Renal Physiology. Oct, 2006 | Pubmed ID: 16597613 Cd2+-induced Swelling-contraction Dynamics in Isolated Kidney Cortex Mitochondria: Role of Ca2+ Uniporter, K+ Cycling, and Protonmotive Force American Journal of Physiology. Cell Physiology. Sep, 2005 | Pubmed ID: 15843441 Cd(2+)-induced Cytochrome C Release in Apoptotic Proximal Tubule Cells: Role of Mitochondrial Permeability Transition Pore and Ca(2+) Uniporter American Journal of Physiology. Renal Physiology. Jan, 2005 | Pubmed ID: 15339793 Mitochondria As a Target of Cadmium Nephrotoxicity: Induction of Swelling and Cytochrome C Release Toxicology Mechanisms and Methods. 2004 | Pubmed ID: 20021126 Optical Spatial Solitons Supported by Photoisomerization Nonlinearity in a Polymer Optics Letters. Feb, 2004 | Pubmed ID: 14759050 유동 세포 계측법에 의한 신장 상피 세포에서 세포 내 칼슘 측정 Wing-Kee Lee1, Thomas Dittmar2 1Institute for Physiology, Pathophysiology, & Toxicology, Centre for Biomedical Research and Training (ZBAF), University of Witten/Herdecke, 2Institute for Immunology & Experimental Oncology, Centre for Biomedical Research and Training (ZBAF), University of Witten/Herdecke JoVE 51857 Biologia
유동 세포 계측법에 의한 신장 상피 세포에서 세포 내 칼슘 측정 Wing-Kee Lee1, Thomas Dittmar2 1Institute for Physiology, Pathophysiology, & Toxicology, Centre for Biomedical Research and Training (ZBAF), University of Witten/Herdecke, 2Institute for Immunology & Experimental Oncology, Centre for Biomedical Research and Training (ZBAF), University of Witten/Herdecke JoVE 51857 Biologia