Xiao-Ying Yu Earth & Biological Sciences Directorate Pacific Northwest National Laboratory Biography Publications Institution JoVE Articles Xiao-Ying Yu Dr. Yu was trained as a physical chemist and kineticist at the University of Michigan, Ann Arbor, MI. She did her postdoctoral research at Brookhaven National Laboratory and Colorado State University. She has been a senior scientist at Pacific Northwest National Laboratory since 2006. She has led the development of a novel mesoscale imaging tool based on microfluidics at PNNL since 2008, which has resulted in three patents, a prestigious R&D 100 award, and a Federal Laboratory Consortium Technology Transfer Excellence Award. Her inventions enabled in situ liquid analysis using surface sensitive tools like SEM and ToF-SIMS that are traditionally limited to solid analysis. She has developed new concepts in aerosol sampling, led and participated in many field studies for in situ measurements of aerosols. Dr. Yu is the chair of the DOE chemical exposure working group; and leads the development of protective action criteria (PAC) and chemical mixture methodology (CMM) for consequence assessment of toxic health effects. Her research focuses on in situ mesoscale chemical imaging of soft materials in atmospheric, biology, energy, and material sciences using microfluidics. Publications Secondary Ion Mass Spectrometry: The Application in the Analysis of Atmospheric Particulate Matter Analytica Chimica Acta. Oct, 2017 | Pubmed ID: 28915935 Recent Developments in the Synthesis, Properties, and Biomedical Applications of Core/shell Superparamagnetic Iron Oxide Nanoparticles with Gold Biomaterials Science. Sep, 2017 | Pubmed ID: 28901350 An Investigation of the Beam Damage Effect on In Situ Liquid SIMS Analysis Rapid Communications in Mass Spectrometry : RCM. Sep, 2017 | Pubmed ID: 28884926 Effects of Humic Acid on the Interactions Between Zinc Oxide Nanoparticles and Bacterial Biofilms Environmental Pollution (Barking, Essex : 1987). Aug, 2017 | Pubmed ID: 28851497 Characterization of Syntrophic Geobacter Communities Using ToF-SIMS Biointerphases. Aug, 2017 | Pubmed ID: 28821212 Molecular Investigation on the Binding of Cd(II) by the Binary Mixtures of Montmorillonite with Two Bacterial Species Environmental Pollution (Barking, Essex : 1987). Jul, 2017 | Pubmed ID: 28754562 Two Coexisting Liquid Phases in Switchable Ionic Liquids Physical Chemistry Chemical Physics : PCCP. Jun, 2017 | Pubmed ID: 28664967 Deciphering the Aqueous Chemistry of Glyoxal Oxidation with Hydrogen Peroxide Using Molecular Imaging Physical Chemistry Chemical Physics : PCCP. Aug, 2017 | Pubmed ID: 28597894 PKM2-mediated Inhibition of Autophagy Facilitates Tat's Inducing HIV-1 Transactivation Archives of Biochemistry and Biophysics. Jul, 2017 | Pubmed ID: 28583828 Loss of TET1 Facilitates DLD1 Colon Cancer Cell Migration Via H3K27me3-mediated Down-regulation of E-cadherin Journal of Cellular Physiology. May, 2017 | Pubmed ID: 28513825 In Situ Mass Spectrometric Monitoring of the Dynamic Electrochemical Process at the Electrode-Electrolyte Interface: a SIMS Approach Analytical Chemistry. Jan, 2017 | Pubmed ID: 27936704 In Situ Molecular Imaging of the Biofilm and Its Matrix Analytical Chemistry. Nov, 2016 | Pubmed ID: 27709903 Modeling and Qualification of a Modified Emission Unit for Radioactive Air Emissions Stack Sampling Compliance Health Physics. Nov, 2016 | Pubmed ID: 27682902 UTX-1 Regulates Tat-induced HIV-1 Transactivation Via Changing the Methylated Status of Histone H3 The International Journal of Biochemistry & Cell Biology. Nov, 2016 | Pubmed ID: 27671333 Improving the Molecular Ion Signal Intensity for In Situ Liquid SIMS Analysis Journal of the American Society for Mass Spectrometry. Dec, 2016 | Pubmed ID: 27600576 Capturing the Transient Species at the Electrode-electrolyte Interface by in Situ Dynamic Molecular Imaging Chemical Communications (Cambridge, England). Sep, 2016 | Pubmed ID: 27500288 Preparation of Reduced-Graphene Nanoribbons Via One-Step Solvothermal Process Journal of Nanoscience and Nanotechnology. Apr, 2016 | Pubmed ID: 27451785 Chemical Imaging of Molecular Changes in a Hydrated Single Cell by Dynamic Secondary Ion Mass Spectrometry and Super-resolution Microscopy Integrative Biology : Quantitative Biosciences from Nano to Macro. May, 2016 | Pubmed ID: 27053104 Two-dimensional and Three-dimensional Dynamic Imaging of Live Biofilms in a Microchannel by Time-of-flight Secondary Ion Mass Spectrometry Biomicrofluidics. May, 2015 | Pubmed ID: 26015837 [Comparison of Anterior Chamber Angle Examination by UBM, SL-OCT and Gonioscopy] Fa Yi Xue Za Zhi. Aug, 2014 | Pubmed ID: 25507685 [Comparison of Anterior Chamber Angle Examination by UBM, SL-OCT and Gonioscopy] Fa Yi Xue Za Zhi. Aug, 2014 | Pubmed ID: 25434087 In Situ Molecular Imaging of a Hydrated Biofilm in a Microfluidic Reactor by ToF-SIMS The Analyst. Apr, 2014 | Pubmed ID: 24571001 In Situ Chemical Probing of the Electrode-electrolyte Interface by ToF-SIMS Lab on a Chip. Mar, 2014 | Pubmed ID: 24356670 Fast in Situ Airborne Measurement of Ammonia Using a Mid-infrared Off-axis ICOS Spectrometer Environmental Science & Technology. Sep, 2013 | Pubmed ID: 23869496 Enhancing the Chemical Mixture Methodology in Emergency Preparedness and Consequence Assessment Analysis Toxicology. Nov, 2013 | Pubmed ID: 23182768 [Clinical Observation on Combination of Compound Xuanju Capsule and Clomiphene Citrate in Treating Ovulatory Dysfunctional Infertility Patients of Shen-yang Deficiency] Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine / Zhongguo Zhong Xi Yi Jie He Xue Hui, Zhongguo Zhong Yi Yan Jiu Yuan Zhu Ban. Jul, 2012 | Pubmed ID: 23019938 An Association Study of HFE Gene Mutation with Idiopathic Male Infertility in the Chinese Han Population Asian Journal of Andrology. Jul, 2012 | Pubmed ID: 22504868 Probing Liquid Surfaces Under Vacuum Using SEM and ToF-SIMS Lab on a Chip. Aug, 2011 | Pubmed ID: 21670825 The Development and Application of the Chemical Mixture Methodology in Analysis of Potential Health Impacts from Airborne Release in Emergencies Journal of Applied Toxicology : JAT. Aug, 2010 | Pubmed ID: 20635331 [Characteristics of Soil Seed Banks in Different Water Level Areas After Returning Farmland into Lake in Qingshanyuan of Dongting Lake] Ying Yong Sheng Tai Xue Bao = The Journal of Applied Ecology / Zhongguo Sheng Tai Xue Xue Hui, Zhongguo Ke Xue Yuan Shenyang Ying Yong Sheng Tai Yan Jiu Suo Zhu Ban. Jun, 2009 | Pubmed ID: 19795640 Characterization of the Sunset Semi-continuous Carbon Aerosol Analyzer Journal of the Air & Waste Management Association (1995). Jul, 2009 | Pubmed ID: 19645267 A Study of Aortic Dimension in Type B Aortic Dissection Interactive Cardiovascular and Thoracic Surgery. Apr, 2008 | Pubmed ID: 18187457 Analysis of Anions in Ambient Aerosols by Microchip Capillary Electrophoresis The Analyst. Nov, 2006 | Pubmed ID: 17066191 Particulate Nitrate Measurement Using Nylon Filters Journal of the Air & Waste Management Association (1995). Aug, 2005 | Pubmed ID: 16187580 SLC18A2 Promoter Haplotypes and Identification of a Novel Protective Factor Against Alcoholism Human Molecular Genetics. May, 2005 | Pubmed ID: 15829504 The Human Serotonin Receptor 2B: Coding Region Polymorphisms and Association with Vulnerability to Illegal Drug Abuse Pharmacogenetics. Dec, 2004 | Pubmed ID: 15608559 MRNA for Genes Associated with Antigen Presentation Are Expressed by Human Middle Meatal Epithelial Cells in Culture The Laryngoscope. Oct, 2004 | Pubmed ID: 15454780 Expression of Genes for B7-H3 and Other T Cell Ligands by Nasal Epithelial Cells During Differentiation and Activation American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2004 | Pubmed ID: 15047568 [Effects of Head Down Bed Rest or Drinking Water Containing Electrolytic Silver-ion on Intestinal Bifidobacteria] Hang Tian Yi Xue Yu Yi Xue Gong Cheng = Space Medicine & Medical Engineering. Jun, 2002 | Pubmed ID: 12222574 Synergism Between Rhinovirus Infection and Oxidant Pollutant Exposure Enhances Airway Epithelial Cell Cytokine Production Environmental Health Perspectives. Jul, 2002 | Pubmed ID: 12117643 [Effects of Nitric Oxide on Myocardial Contraction Function] Hang Tian Yi Xue Yu Yi Xue Gong Cheng = Space Medicine & Medical Engineering. Apr, 2002 | Pubmed ID: 12068888 Imaging korrosjon på metal-Paint Interface bruke time-of-Flight sekundær ion Mass massespektrometri Jennifer Yao1, Anthony Guzman2, Zihua Zhu3, Xiao-Ying Yu1 1Earth and Biological Sciences Directorate, Pacific Northwest National Laboratory, 2Energy and Environment Directorate, Pacific Northwest National Laboratory, 3Wiley Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory JoVE 59523 Chimica In Situ Karakterisering av Boehmite partikler i vann med flytende SEM Juan Yao1, Bruce W. Arey1, Li Yang1, Fei Zhang1, Rachel Komorek1, Jaehun Chun1, Xiao-Ying Yu1 1Earth & Biological Sciences Directorate, Pacific Northwest National Laboratory JoVE 56058 Chimica In Situ Karakterisering av Shewanella oneidensis MR1 biofilm SALVI og ToF-SIMS Rachel Komorek1, Wenchao Wei1, Xiaofei Yu2, Eric Hill1, Juan Yao1, Zihua Zhu2, Xiao-Ying Yu1 1Earth and Biological Sciences Directorate, Pacific Northwest National Laboratory, 2Wiley Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory JoVE 55944 Chimica In Situ Karakterisering av Hydratiserte Proteiner i vann ved Salvi og TOF-SIMS Jiachao Yu1, Yufan Zhou*2, Xin Hua*1, Zihua Zhu2, Xiao-Ying Yu1 1Fundamental & Computational Sciences Directorate, Pacific Northwest National Laboratory, 2Wiley Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory JoVE 53708 Chimica
Imaging korrosjon på metal-Paint Interface bruke time-of-Flight sekundær ion Mass massespektrometri Jennifer Yao1, Anthony Guzman2, Zihua Zhu3, Xiao-Ying Yu1 1Earth and Biological Sciences Directorate, Pacific Northwest National Laboratory, 2Energy and Environment Directorate, Pacific Northwest National Laboratory, 3Wiley Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory JoVE 59523 Chimica
In Situ Karakterisering av Boehmite partikler i vann med flytende SEM Juan Yao1, Bruce W. Arey1, Li Yang1, Fei Zhang1, Rachel Komorek1, Jaehun Chun1, Xiao-Ying Yu1 1Earth & Biological Sciences Directorate, Pacific Northwest National Laboratory JoVE 56058 Chimica
In Situ Karakterisering av Shewanella oneidensis MR1 biofilm SALVI og ToF-SIMS Rachel Komorek1, Wenchao Wei1, Xiaofei Yu2, Eric Hill1, Juan Yao1, Zihua Zhu2, Xiao-Ying Yu1 1Earth and Biological Sciences Directorate, Pacific Northwest National Laboratory, 2Wiley Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory JoVE 55944 Chimica
In Situ Karakterisering av Hydratiserte Proteiner i vann ved Salvi og TOF-SIMS Jiachao Yu1, Yufan Zhou*2, Xin Hua*1, Zihua Zhu2, Xiao-Ying Yu1 1Fundamental & Computational Sciences Directorate, Pacific Northwest National Laboratory, 2Wiley Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory JoVE 53708 Chimica