Ylva Hellsten Section of Integrative Physiology, Department of Nutrition, Exercise and Sports University of Copenhagen Biography Publications Institution JoVE Articles Ylva Hellsten has not added a biography. If you are Ylva Hellsten and would like to personalize this page please email our Author Liaison for assistance. Publications AXIN1 Knockout Does Not Alter AMPK/mTORC1 Regulation and Glucose Metabolism in Mouse Skeletal Muscle The Journal of Physiology. Apr, 2021 | Pubmed ID: 33913171 Effect of Aerobic Exercise Training on Asthma Control in Postmenopausal Women (the ATOM-study): Protocol for an Outcome Assessor, Randomised Controlled Trial BMJ Open. Apr, 2021 | Pubmed ID: 33888532 Histamine H and H Receptors Are Essential Transducers of the Integrative Exercise Training Response in Humans Science Advances. Apr, 2021 | Pubmed ID: 33853781 A High Activity Level Is Required for Augmented Muscle Capillarization in Older Women Medicine and Science in Sports and Exercise. May, 2021 | Pubmed ID: 33844669 The Impact of Lower Limb Immobilization and Rehabilitation on Angiogenic Proteins and Capillarization in Skeletal Muscle Medicine and Science in Sports and Exercise. Mar, 2021 | Pubmed ID: 33787530 Does Exercise Influence the Susceptibility to Arterial Thrombosis? An Integrative Perspective Frontiers in Physiology. 2021 | Pubmed ID: 33708141 Effects of High-Intensity Exercise Training on Adipose Tissue Mass, Glucose Uptake and Protein Content in Pre- and Post-menopausal Women Frontiers in Sports and Active Living. 2020 | Pubmed ID: 33345051 Commentaries on Point:Counterpoint: Investigators Should/should Not Control for Menstrual Cycle Phase when Performing Studies of Vascular Control Journal of Applied Physiology (Bethesda, Md. : 1985). 11, 2020 | Pubmed ID: 33197376 Assessment of Diabetic Foot Ulcers Based on Pictorial Material: an Interobserver Study Journal of Wound Care. Nov, 2020 | Pubmed ID: 33175625 Ischemic Preconditioning Improves Microvascular Endothelial Function in Remote Vasculature by Enhanced Prostacyclin Production Journal of the American Heart Association. 08, 2020 | Pubmed ID: 32750305 Inducible Deletion of Skeletal Muscle AMPKα Reveals That AMPK is Required for Nucleotide Balance but Dispensable for Muscle Glucose Uptake and Fat Oxidation During Exercise Molecular Metabolism. 10, 2020 | Pubmed ID: 32504885 Microvascular Function Is Impaired After Short-Term Immobilization in Healthy Men Medicine and Science in Sports and Exercise. 10, 2020 | Pubmed ID: 32496738 Effect of Aerobic Exercise Training on Asthma in Adults: a Systematic Review and Meta-analysis The European Respiratory Journal. 07, 2020 | Pubmed ID: 32350100 Early Time Course of Change in Angiogenic Proteins in Human Skeletal Muscle and Vascular Cells with Endurance Training Scandinavian Journal of Medicine & Science in Sports. Jul, 2020 | Pubmed ID: 32246511 The Impact of Acute Remote Ischaemic Preconditioning on Cerebrovascular Function European Journal of Applied Physiology. Mar, 2020 | Pubmed ID: 31932877 Assessment of Resistance Vessel Function in Human Skeletal Muscle: Guidelines for Experimental Design, Doppler Ultrasound, and Pharmacology American Journal of Physiology. Heart and Circulatory Physiology. 02, 2020 | Pubmed ID: 31886718 Insulin-induced Membrane Permeability to Glucose in Human Muscles at Rest and Following Exercise The Journal of Physiology. 01, 2020 | Pubmed ID: 31696935 Lifelong Physical Activity Determines Vascular Function in Late Postmenopausal Women Medicine and Science in Sports and Exercise. 03, 2020 | Pubmed ID: 31609299 Hyperinsulinemia Does Not Cause De Novo Capillary Recruitment in Rat Skeletal Muscle Microcirculation (New York, N.Y. : 1994). 02, 2020 | Pubmed ID: 31605649 On the Horizon of Aging and Physical Activity Research Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. Feb, 2020 | Pubmed ID: 31314999 Early Sarcomere and Metabolic Defects in a Zebrafish Cardiac Arrhythmia Model Proceedings of the National Academy of Sciences of the United States of America. 11, 2019 | Pubmed ID: 31704768 Seven-day Remote Ischaemic Preconditioning Improves Endothelial Function in Patients with Type 2 Diabetes Mellitus: a Randomised Pilot Study European Journal of Endocrinology. Dec, 2019 | Pubmed ID: 31614332 Oestrogen, Exercise and Vascular Function The Journal of Physiology. 10, 2019 | Pubmed ID: 31571227 Muscle-strain Injury Exudate Favors Acute Tissue Healing and Prolonged Connective Tissue Formation in Humans FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 09, 2019 | Pubmed ID: 31211922 Regulatory Mechanisms of Estrogen on Vascular Ageing Oxidative Medicine and Cellular Longevity. 2019 | Pubmed ID: 31182992 Cardiac Perfusion and Function After High-intensity Exercise Training in Late Premenopausal and Recent Postmenopausal Women: an MRI Study Journal of Applied Physiology (Bethesda, Md. : 1985). 05, 2019 | Pubmed ID: 30870082 Copenhagen Consensus Statement 2019: Physical Activity and Ageing British Journal of Sports Medicine. Jul, 2019 | Pubmed ID: 30792257 Reduced Skeletal-muscle Perfusion and Impaired ATP Release During Hypoxia and Exercise in Individuals with Type 2 Diabetes Diabetologia. 03, 2019 | Pubmed ID: 30607464 The Effect of Two Exercise Modalities on Skeletal Muscle Capillary Ultrastructure in Individuals with Type 2 Diabetes Scandinavian Journal of Medicine & Science in Sports. Mar, 2019 | Pubmed ID: 30480353 Effect of Menopause and Exercise Training on Plasma Apolipoprotein M and Sphingosine-1-phosphate Journal of Applied Physiology (Bethesda, Md. : 1985). 01, 2019 | Pubmed ID: 30433864 The Endothelial Mechanotransduction Protein Platelet Endothelial Cell Adhesion Molecule-1 Is Influenced by Aging and Exercise Training in Human Skeletal Muscle Frontiers in Physiology. 2018 | Pubmed ID: 30618819 The Effect of Tyramine Infusion and Exercise on Blood Flow, Coagulation and Clot Microstructure in Healthy Individuals Thrombosis Research. 10, 2018 | Pubmed ID: 30098458 Leg Blood Flow and Skeletal Muscle Microvascular Perfusion Responses to Submaximal Exercise in Peripheral Arterial Disease American Journal of Physiology. Heart and Circulatory Physiology. 11, 2018 | Pubmed ID: 30095999 High-intensity Interval, but Not Endurance, Training Induces Muscle Fiber Type-specific Subsarcolemmal Lipid Droplet Size Reduction in Type 2 Diabetic Patients American Journal of Physiology. Endocrinology and Metabolism. 11, 2018 | Pubmed ID: 30016151 Methods for the Determination of Skeletal Muscle Blood Flow: Development, Strengths and Limitations European Journal of Applied Physiology. Jun, 2018 | Pubmed ID: 29756164 Effects of Aging and Exercise Training on Leg Hemodynamics and Oxidative Metabolism in the Transition from Rest to Steady-state Exercise: Role of CGMP Signaling American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 08, 2018 | Pubmed ID: 29668326 Probenecid Inhibits α-Adrenergic Receptor-Mediated Vasoconstriction in the Human Leg Vasculature Hypertension (Dallas, Tex. : 1979). 01, 2018 | Pubmed ID: 29084879 Exercise Training Improves Blood Flow to Contracting Skeletal Muscle of Older Men Via Enhanced CGMP Signaling Journal of Applied Physiology (Bethesda, Md. : 1985). 01, 2018 | Pubmed ID: 28982945 Effects of Menopause and High-intensity Training on Insulin Sensitivity and Muscle Metabolism Menopause (New York, N.Y.). 02, 2018 | Pubmed ID: 28953212 Impact of β-adrenergic Signaling in PGC-1α-mediated Adaptations in Mouse Skeletal Muscle American Journal of Physiology. Endocrinology and Metabolism. 01, 2018 | Pubmed ID: 28874356 Cardiac Adaptations to High-Intensity Aerobic Training in Premenopausal and Recent Postmenopausal Women: The Copenhagen Women Study Journal of the American Heart Association. Aug, 2017 | Pubmed ID: 28862950 Endothelial Mechanotransduction Proteins and Vascular Function Are Altered by Dietary Sucrose Supplementation in Healthy Young Male Subjects The Journal of Physiology. 08, 2017 | Pubmed ID: 28620941 The Effect of Nitric Oxide Synthase Inhibition with and Without Inhibition of Prostaglandins on Blood Flow in Different Human Skeletal Muscles European Journal of Applied Physiology. Jun, 2017 | Pubmed ID: 28432421 Leg Vascular and Skeletal Muscle Mitochondrial Adaptations to Aerobic High-intensity Exercise Training Are Enhanced in the Early Postmenopausal Phase The Journal of Physiology. 05, 2017 | Pubmed ID: 28231611 Effects of High-intensity Training on Cardiovascular Risk Factors in Premenopausal and Postmenopausal Women American Journal of Obstetrics and Gynecology. Apr, 2017 | Pubmed ID: 28024987 Adaptations with Intermittent Exercise Training in Post- and Premenopausal Women Medicine and Science in Sports and Exercise. 01, 2017 | Pubmed ID: 27992397 Effect of Endurance Versus Resistance Training on Quadriceps Muscle Dysfunction in COPD: a Pilot Study International Journal of Chronic Obstructive Pulmonary Disease. 2016 | Pubmed ID: 27822028 Early Postmenopausal Phase Is Associated With Reduced Prostacyclin-Induced Vasodilation That Is Reversed by Exercise Training: The Copenhagen Women Study Hypertension (Dallas, Tex. : 1979). 10, 2016 | Pubmed ID: 27550922 Effects of Exercise Training and Resveratrol on Vascular Health in Aging Free Radical Biology & Medicine. 09, 2016 | Pubmed ID: 27085843 Limitations of Skeletal Muscle Oxygen Supply in Ageing The Journal of Physiology. Apr, 2016 | Pubmed ID: 27079630 Capillary Ultrastructure and Mitochondrial Volume Density in Skeletal Muscle in Relation to Reduced Exercise Capacity of Patients with Intermittent Claudication American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 05, 2016 | Pubmed ID: 27009051 Vasoactive Enzymes and Blood Flow Responses to Passive and Active Exercise in Peripheral Arterial Disease Atherosclerosis. Mar, 2016 | Pubmed ID: 26771386 Advances and Challenges in Skeletal Muscle Angiogenesis American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2016 | Pubmed ID: 26608338 Reduced Blood Flow to Contracting Skeletal Muscle in Ageing Humans: is It All an Effect of Sand Through the Hourglass? The Journal of Physiology. Apr, 2016 | Pubmed ID: 26095873 Optimizing Hyaluronidase Dose and Plasmid DNA Delivery Greatly Improves Gene Electrotransfer Efficiency in Rat Skeletal Muscle Biochemistry and Biophysics Reports. Dec, 2015 | Pubmed ID: 29124223 Cardiovascular Adaptations to Exercise Training Comprehensive Physiology. Dec, 2015 | Pubmed ID: 26756625 Effect of PDE5 Inhibition on the Modulation of Sympathetic α-adrenergic Vasoconstriction in Contracting Skeletal Muscle of Young and Older Recreationally Active Humans American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2015 | Pubmed ID: 26432842 Potentiation of CGMP Signaling Increases Oxygen Delivery and Oxidative Metabolism in Contracting Skeletal Muscle of Older but Not Young Humans Physiological Reports. Aug, 2015 | Pubmed ID: 26272735 What Turns off the Angiogenic Switch in Skeletal Muscle? Experimental Physiology. Jul, 2015 | Pubmed ID: 26130184 Effects of Exercise Training on Regulation of Skeletal Muscle Glucose Metabolism in Elderly Men The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Jul, 2015 | Pubmed ID: 25991826 10-20-30 Training Increases Performance and Lowers Blood Pressure and VEGF in Runners Scandinavian Journal of Medicine & Science in Sports. Oct, 2015 | Pubmed ID: 25439558 Bengt Saltin (1935-2014) The Journal of Physiology. Dec, 2014 | Pubmed ID: 25448186 Capillary Growth in Human Skeletal Muscle: Physiological Factors and the Balance Between Pro-angiogenic and Angiostatic Factors Biochemical Society Transactions. Dec, 2014 | Pubmed ID: 25399579 Increased Skeletal Muscle Capillarization Enhances Insulin Sensitivity American Journal of Physiology. Endocrinology and Metabolism. Dec, 2014 | Pubmed ID: 25352432 Resveratrol Modulates the Angiogenic Response to Exercise Training in Skeletal Muscles of Aged Men American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2014 | Pubmed ID: 25128170 Infusion of ATP Increases Leg Oxygen Delivery but Not Oxygen Uptake in the Initial Phase of Intense Knee-extensor Exercise in Humans Experimental Physiology. Oct, 2014 | Pubmed ID: 25085840 Exercise Training Modulates Functional Sympatholysis and α-adrenergic Vasoconstrictor Responsiveness in Hypertensive and Normotensive Individuals The Journal of Physiology. Jul, 2014 | Pubmed ID: 24860173 Roles of Sedentary Aging and Lifelong Physical Activity in Exchange of Glutathione Across Exercising Human Skeletal Muscle Free Radical Biology & Medicine. Aug, 2014 | Pubmed ID: 24858720 Biomarkers of Vascular Function in Premenopausal and Recent Postmenopausal Women of Similar Age: Effect of Exercise Training American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Apr, 2014 | Pubmed ID: 24477543 Exercise-induced Capillary Growth in Human Skeletal Muscle and the Dynamics of VEGF Microcirculation (New York, N.Y. : 1994). May, 2014 | Pubmed ID: 24450403 Effect of Lifelong Resveratrol Supplementation and Exercise Training on Skeletal Muscle Oxidative Capacity in Aging Mice; Impact of PGC-1α Experimental Gerontology. Nov, 2013 | Pubmed ID: 23994519 Effect of Nitric Oxide Synthase Inhibition on the Exchange of Glucose and Fatty Acids in Human Skeletal Muscle Nutrition & Metabolism. Jun, 2013 | Pubmed ID: 23773265 Effect of Extraluminal ATP Application on Vascular Tone and Blood Flow in Skeletal Muscle: Implications for Exercise Hyperemia American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2013 | Pubmed ID: 23761642 Leg Oxygen Uptake in the Initial Phase of Intense Exercise is Slowed by a Marked Reduction in Oxygen Delivery American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2013 | Pubmed ID: 23720134 Subcellular Localization and Mechanism of Secretion of Vascular Endothelial Growth Factor in Human Skeletal Muscle FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2013 | Pubmed ID: 23709615 Impaired Formation of Vasodilators in Peripheral Tissue in Essential Hypertension is Normalized by Exercise Training: Role of Adenosine and Prostacyclin Journal of Hypertension. Oct, 2012 | Pubmed ID: 22902871 Lifelong Physical Activity Prevents an Age-related Reduction in Arterial and Skeletal Muscle Nitric Oxide Bioavailability in Humans The Journal of Physiology. Nov, 2012 | Pubmed ID: 22890714 Energy Metabolism During Repeated Sets of Leg Press Exercise Leading to Failure or Not PloS One. 2012 | Pubmed ID: 22808209 Opposing Effects of Nitric Oxide and Prostaglandin Inhibition on Muscle Mitochondrial Vo(2) During Exercise American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jul, 2012 | Pubmed ID: 22552792 Skeletal Muscle PGC-1α is Required for Maintaining an Acute LPS-induced TNFα Response PloS One. 2012 | Pubmed ID: 22384185 Role of Nitric Oxide and Prostanoids in the Regulation of Leg Blood Flow and Blood Pressure in Humans with Essential Hypertension: Effect of High-intensity Aerobic Training The Journal of Physiology. Mar, 2012 | Pubmed ID: 22271868 Exercise Training Alters the Balance Between Vasoactive Compounds in Skeletal Muscle of Individuals with Essential Hypertension Hypertension (Dallas, Tex. : 1979). Nov, 2011 | Pubmed ID: 21896936 Interstitial and Plasma Adenosine Stimulate Nitric Oxide and Prostacyclin Formation in Human Skeletal Muscle Hypertension (Dallas, Tex. : 1979). Dec, 2010 | Pubmed ID: 21041702 Anaerobic Energy Expenditure and Mechanical Efficiency During Exhaustive Leg Press Exercise PloS One. Oct, 2010 | Pubmed ID: 20976067 Contraction-induced Secretion of VEGF from Skeletal Muscle Cells is Mediated by Adenosine American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2010 | Pubmed ID: 20543089 Exercise Training Normalizes Skeletal Muscle Vascular Endothelial Growth Factor Levels in Patients with Essential Hypertension Journal of Hypertension. Jun, 2010 | Pubmed ID: 20179634 Attenuated Purinergic Receptor Function in Patients with Type 2 Diabetes Diabetes. Jan, 2010 | Pubmed ID: 19808895 PGC-1alpha Mediates Exercise-induced Skeletal Muscle VEGF Expression in Mice American Journal of Physiology. Endocrinology and Metabolism. Jul, 2009 | Pubmed ID: 19401459 Partial Neuromuscular Blockade in Humans Enhances Muscle Blood Flow During Exercise Independently of Muscle Oxygen Uptake and Acetylcholine Receptor Blockade American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Apr, 2009 | Pubmed ID: 19193948 Four Weeks of Speed Endurance Training Reduces Energy Expenditure During Exercise and Maintains Muscle Oxidative Capacity Despite a Reduction in Training Volume Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2009 | Pubmed ID: 18845781 Reduced Volume but Increased Training Intensity Elevates Muscle Na+-K+ Pump Alpha1-subunit and NHE1 Expression As Well As Short-term Work Capacity in Humans American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2008 | Pubmed ID: 18094063 Passive Leg Movement Enhances Interstitial VEGF Protein, Endothelial Cell Proliferation, and ENOS MRNA Content in Human Skeletal Muscle American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2008 | Pubmed ID: 18094062 PGC-1alpha is Not Mandatory for Exercise- and Training-induced Adaptive Gene Responses in Mouse Skeletal Muscle American Journal of Physiology. Endocrinology and Metabolism. Feb, 2008 | Pubmed ID: 18073319 Absence of Humoral Mediated 5'AMP-activated Protein Kinase Activation in Human Skeletal Muscle and Adipose Tissue During Exercise The Journal of Physiology. Dec, 2007 | Pubmed ID: 17962330 Antioxidant Supplementation Enhances the Exercise-induced Increase in Mitochondrial Uncoupling Protein 3 and Endothelial Nitric Oxide Synthase MRNA Content in Human Skeletal Muscle Free Radical Biology & Medicine. Aug, 2007 | Pubmed ID: 17602951 Calcium Signalling in the Regulation of PGC-1alpha, PDK4 and HKII MRNA Expression Biological Chemistry. May, 2007 | Pubmed ID: 17516843 Caffeine-induced Ca(2+) Release Increases AMPK-dependent Glucose Uptake in Rodent Soleus Muscle American Journal of Physiology. Endocrinology and Metabolism. Jul, 2007 | Pubmed ID: 17405829 Effects of Alpha-AMPK Knockout on Exercise-induced Gene Activation in Mouse Skeletal Muscle FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2005 | Pubmed ID: 15878932 Intense Interval Training Enhances Human Skeletal Muscle Oxygen Uptake in the Initial Phase of Dynamic Exercise at High but Not at Low Intensities The Journal of Physiology. Aug, 2004 | Pubmed ID: 15235098 Exercise but Not Prostanoids Enhance Levels of Vascular Endothelial Growth Factor and Other Proliferative Agents in Human Skeletal Muscle Interstitium The Journal of Physiology. Jul, 2003 | Pubmed ID: 12754306 Cytochrome P450 2C9 Plays an Important Role in the Regulation of Exercise-induced Skeletal Muscle Blood Flow and Oxygen Uptake in Humans The Journal of Physiology. Jan, 2003 | Pubmed ID: 12509498 Regulation of 5'AMP-activated Protein Kinase Activity and Substrate Utilization in Exercising Human Skeletal Muscle American Journal of Physiology. Endocrinology and Metabolism. Apr, 2003 | Pubmed ID: 12488245 Glycogen-dependent Effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated Protein Kinase and Glycogen Synthase Activities in Rat Skeletal Muscle Diabetes. Feb, 2002 | Pubmed ID: 11812734 The Effect of Muscle Contraction on the Regulation of Adenosine Formation in Rat Skeletal Muscle Cells The Journal of Physiology. Aug, 1999 | Pubmed ID: 10420012 Messung der insulin- und kontraktionsstimulierten Glukoseaufnahme in isolierten und inkubierten reifen Skelettmuskeln von Mäusen Rasmus Kjøbsted1, Kohei Kido1, Jeppe K. Larsen1, Nicolas O. Jørgensen1, Jesper B. Birk1, Ylva Hellsten2, Jørgen F. P. Wojtaszewski1 1Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen, 2Section of Integrative Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen JoVE 61398 Biologia
Messung der insulin- und kontraktionsstimulierten Glukoseaufnahme in isolierten und inkubierten reifen Skelettmuskeln von Mäusen Rasmus Kjøbsted1, Kohei Kido1, Jeppe K. Larsen1, Nicolas O. Jørgensen1, Jesper B. Birk1, Ylva Hellsten2, Jørgen F. P. Wojtaszewski1 1Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen, 2Section of Integrative Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen JoVE 61398 Biologia
