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JoVE Journal Neuroscience
Intravital Microscopy of the Mouse Brain Microcirculation using a Closed Cranial Window
 
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Intravital Microscopy of the Mouse Brain Microcirculation using a Closed Cranial Window

Article DOI: 10.3791/2184-v • 08:37 min • November 18th, 2010
November 18th, 2010 •
1, 2
1Bioengineering, University of California, San Diego, 2La Jolla Bioengineering Institute

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Intravital microscopy to follow temporal and spatial hemodynamic and inflammatory events in the pial microcirculation.

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Intravital Microscopy Mouse Brain Microcirculation Closed Cranial Window Acute Conditions Chronic Conditions Physiological Conditions Pathophysiological Conditions In Vivo Fluorescence Microscopy Pial Microcirculation Real-time Recording Epi Illumination Fluorescence Illumination Vessel Diameters Red Blood Cell Velocities RBC Velocity Measurement Cross-correlation Fluorescent-labeled Erythrocytes Leukocyte Adherence Platelet Adherence Perfusion Assessment Vascular Leakage Assessment Fluorescence-labeled Markers Albumin-FITC Marker Anti-CD45-TxR Antibodies Video Recording Plasmodium Berghei ANKA Infection Microcirculatory Dysfunctions
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