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Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury
 

Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury

Article DOI: 10.3791/3069-v • 10:49 min • September 18th, 2011
September 18th, 2011 •
1
1Department of Neuroscience, Thomas Jefferson University Medical College

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Riepilogo
Automatic Translation

Neural precursor transplantation is a promising strategy for protecting and/or replacing lost/dysfunctional cervical phrenic motor neurons in spinal cord injury (SCI) and the motor neuron disorder, amyotrophic laterals sclerosis (ALS). We provide a protocol for cell delivery to cervical spinal cord ventral horn in rodent models of ALS and SCI.

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Intraspinal Cell Transplantation Targeting Cervical Ventral Horn Amyotrophic Lateral Sclerosis Traumatic Spinal Cord Injury Respiratory Compromise Phrenic Motor Neuron Loss Motor Neuron Disorder Rapid Degeneration Upper And Lower Motor Neurons Respiratory Paralysis Diaphragm Innervation Familial Cases Cu/Zn Superoxide Dismutase 1 Gene SOD1 Gene Mutations Transgenic Mice And Rats Animal Models Spinal Cord Injury Heterogeneous Conditions
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