Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Biology / Visualization of Mitochondrial Respiratory…
JoVE Journal
Biology

È necessario avere un abbonamento a JoVE per visualizzare questo Contenuto. Accedi o inizia la tua prova gratuita.

JoVE Journal Biology
Visualization of Mitochondrial Respiratory Function using Cytochrome C Oxidase / Succinate Dehydrogenase (COX/SDH) Double-labeling Histochemistry
 

Visualization of Mitochondrial Respiratory Function using Cytochrome C Oxidase / Succinate Dehydrogenase (COX/SDH) Double-labeling Histochemistry

Article DOI: 10.3791/3266-v • 06:54 min • November 23rd, 2011
November 23rd, 2011 •
1,2
1Department of Neuroscience, Karolinska Institutet, 2National Institute on Drug Abuse (NIDA)

Capitoli

Riepilogo
Automatic Translation

The cytochrome c oxidase/sodium dehydrogenase (COX/SDH) double-labeling method allows for direct visualization of mitochondrial respiratory enzyme deficiencies in fresh-frozen tissue sections. This is a straightforward histochemical technique and is useful in investigating mitochondrial diseases, aging, and aging-related disorders.

Tags

Mitochondrial Respiratory Function Cytochrome C Oxidase Succinate Dehydrogenase COX/SDH Double-labeling Histochemistry Mitochondrial DNA Defects MtDNA Mutations Bioenergetics Homeostasis Cellular Function Mitochondrial Theory Of Aging MtDNA Damage Respiratory Enzymes Cytochrome C Oxidase (COX) MtDNA Integrity Succinate Dehydrogenase (SDH) Nuclear DNA Mitochondrial Diseases Aging Age-related Diseases
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter