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How to Measure Cortical Folding from MR Images
 

How to Measure Cortical Folding from MR Images: a Step-by-Step Tutorial to Compute Local Gyrification Index

Article DOI: 10.3791/3417-v • 09:57 min • January 2nd, 2012
January 2nd, 2012 •
1, 2,3, 4, 4, 2, 1
1Department of Psychiatry, University of Geneva School of Medicine, 2Signal Processing Laboratory, École Polytechnique Fédérale de Lausanne, 3Department of Radiology, University Hospital Center and University of Lausanne, 4Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital

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Measuring gyrification (cortical folding) at any age represents a window into early brain development. Hence, we previously developed an algorithm to measure local gyrification at thousands of points over the hemisphere1. In this paper, we detail the computation of this local gyrification index.

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Measure Cortical Folding MR Images Tutorial Compute Local Gyrification Index Sulcal Morphometry Shape Descriptors Inter-hemispheric Asymmetry Geometrical Properties Sulci Identification Fine-grained Quantification Curvature-based Measurements Absolute Mean Curvature Cortical Surface Curvedness Biologically Meaningful Correlate Cortical Volume Surface Measurement Algorithm
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