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Bioengineering

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JoVE Journal Bioengineering
A Chitosan Based, Laser Activated Thin Film Surgical Adhesive, 'SurgiLux'
 

A Chitosan Based, Laser Activated Thin Film Surgical Adhesive, 'SurgiLux': Preparation and Demonstration

Article DOI: 10.3791/3527-v • 06:32 min • October 23rd, 2012
October 23rd, 2012 •
1, 1
1Bio/Polymer Research Group, School of Biotechnology & Biomolecular Sciences, University of New South Wales

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The fabrication of a novel, flexible thin film surgical adhesive from FDA approved ingredients, chitosan and indocyanine green is described. Bonding of this adhesive to collagenous tissue through a simple activation process with a low-powered infra-red laser is demonstrated.

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Chitosan-based Surgical Adhesive Laser Activated Thin Film SurgiLux Preparation Demonstration Sutures Wound Closure Repair Strength Infection Functional Tissue Regeneration Surgical Glues Adhesives Fibrin Cyanoacrylates Viral Transfer Prion Transfer Tissue Toxicity Biocompatibility Gel-based Adhesives Curing Times UV Lasers Cross-linking Mechanisms Protein-based Solders Albumin Solders DNA Damage Laser Tissue Welding (LTW) Thermal Damage To Tissues Sutureless Technology
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