Rivista
/
Bioingegneria
/
白色念珠菌生物膜芯片（CA BChip）为高通量的抗真菌药物筛选
JoVE Journal
Bioingegneria
È necessario avere un abbonamento a JoVE per visualizzare questo.  Accedi o inizia la tua prova gratuita.
JoVE Journal Bioingegneria
Candida albicans Biofilm Chip (CaBChip) for High-throughput Antifungal Drug Screening
Please note that all translations are automatically generated. Click here for the English version.

白色念珠菌生物膜芯片（CA BChip）为高通量的抗真菌药物筛选

DOI:
10.3791/3845-v

•

08:05 min

•

July 18, 2012

•

, ,
1Department of Biomedical Engineering,University of Texas at San Antonio , 2Department of Biology,University of Texas at San Antonio

Capitoli

  • 00:05Titolo
  • 01:08Preparation of Functionalized Slides
  • 02:30Preparation of Yeast Inocula and Collagen Encapsulation
  • 03:40Preparation of CaBChip
  • 04:57Susceptibility Testing of Preformed Biofilms in CaBChip against Antifungal Agents
  • 06:38Representative Biofilm Chip Results
  • 07:48Conclusion

Summary

Traduzione automatica

Traduzione automatica

我们已经开发出一种高密度芯片平台的3D纳米生物膜的组成<em> C。白念珠菌</em>称为<em>钙</em> BChip。上测试药物的敏感性个人资料<em>钙</em> BChip是传统的96孔板模式相媲美，表明真菌的芯片非常适合真正的高通量筛选抗真菌药物。

Tags

Candida AlbicansBiofilm ChipCaBChipHigh-throughputAntifungal Drug ScreeningCandidiasisNosocomial Bloodstream InfectionCompromised IndividualsMortality RatesAntifungal DrugsResistanceBiofilmsMicroarrayC. Albicans Nano-biofilmsRobotic MicroarrayerYeast CellsSolid SubstrateThree-dimensional MatrixGlass SubstrateCoatingIncubationPhenotypic Characteristics

Article

Embed

AGGIUNGI ALLA PLAYLIST

Usage Statistics

Video correlati

基于细胞中钙含量TRP通道功能的高通量筛选，使用FlexStation 3

聚合物芯片高通量发现的生物材料

一种快速定量荧光方法蛋白靶向小分子药物筛选

使用Tomoauto：一个协议，用于高通量自动化低温电子断层扫描

高通量单细胞的分离和文化的微流体平台

医疗器械细菌高通量鉴定驱蚊聚合物

人工程心脏组织的收缩自动分析心脏药物安全筛选

3D Microtissues 用于可注射再生疗法和高通量药物筛选

高通量自动 Microbioreactor 系统在 CHO 细胞模型 IgG1 生产中的应用

开源微孔板兼容照明面板的应用

Read Article