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Journal / Medicine / Models of Bone Metastasis
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JoVE Journal Medicine
Models of Bone Metastasis
 

Models of Bone Metastasis

Article DOI: 10.3791/4260-v • 08:49 min • September 4th, 2012
September 4th, 2012 •
1,2, 2,3,4, 2,4, 1,2,4,5, 2,3,4,5
1Department of Pharmacology, Vanderbilt University, 2Vanderbilt Center for Bone Biology, Vanderbilt University, 3Department of Veterans Affairs, Tennessee Valley Healthcare System (VISN 9), 4Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University, 5Department of Cancer Biology, Vanderbilt University

Capitoli

Riepilogo
Automatic Translation

Animal models are frequently utilized to study cancer metastasis to bone. In this protocol we will describe two common methods of tumor inoculation for bone metastasis studies and briefly describe some of the analyses utilized to monitor and quantify these models.

Tags

Bone Metastasis Malignancies Breast Cancer Prostate Cancer Lung Cancer Molecular Mechanisms Tumor Growth In Vivo Models Intracardiac Inoculation Athymic BalbC Mice PC-3 Prostate Cancer Lung Carcinoma Mouse Mammary Fat Pad Tumors MDA-MB-231 Breast Cancer Model GFP Expression Osteotropism Metastasis To Lung Liver Adrenal Glands Intratibial Injections Mammary Fat Pad Injections
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