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JoVE Journal Medicine
2-Vessel Occlusie / Hypotensie
 
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2-Vessel Occlusie / Hypotensie: een rat model van Global Brain Ischemie

Article DOI: 10.3791/50173-v • 09:29 min • June 22nd, 2013
June 22nd, 2013 •
1,2,3, 2,3
1Department of Emergency Medicine, Wayne State University School of Medicine, 2Cardiovascular Research Institute, Wayne State University School of Medicine, 3Department of Physiology, Wayne State University School of Medicine

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Bilaterale carotis occlusie combinatie met systemische hypotensie produceert wereldwijde hersenen ischemie in de rat, met schade aan de hippocampus met reproduceerbare ernst. Proefdieren worden verminderd met voorspelbare patronen van hersenbeschadiging, ze herstellen doelmatig en sterftecijfers zijn relatief laag.

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Geneeskunde Biomedische Technologie Neurobiologie Neurologie Immunologie Anatomie Fysiologie Cardiologie Brain ischemie ischemie reperfusie hartstilstand reanimatie 2VOH hersentraumamodel CA1 hippocampus neuronen hersenen neuron bloedvat occlusie hypotensie diermodel
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