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Journal / Behavior / Skabe dynamiske billeder af kortlivede Dopamin…
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Behavior

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JoVE Journal Behavior
Skabe dynamiske billeder af kortlivede Dopamin Udsving med lp-ntPET
 
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Skabe dynamiske billeder af kortlivede Dopamin Udsving med lp-ntPET: Dopamin film af cigaretrygning

Article DOI: 10.3791/50358-v • 14:21 min • August 6th, 2013
August 6th, 2013 •
1,2,3,4, 1,3, 1,3,4, 3,4, 5, 6, 1,2,3
1Diagnostic Radiology, Yale University, 2Psychiatry, Yale University, 3Yale PET Center, Yale University, 4Biomedical Engineering, Yale University, 5Nuclear Medicine, Massachusetts General Hospital, 6Radiological Sciences, University of California, Irvine

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Vi præsenterer en ny PET-billeddannelse tilgang til at opfange dopamin udsving forårsaget af cigaretrygning. Emner røg i PET-skanneren. Dynamiske PET billeder modelleres voxel-by-voxel i tid med lp-ntPET, som omfatter en tidsvarierende dopamin sigt. Resultaterne er "film" af dopamin udsving i striatum under rygning.

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Behavior Neuroscience neurobiologi molekylærbiologi Biomedical Engineering Medicine anatomi fysiologi Image Processing Computer-Assisted receptorer dopamin dopamin Functional Neuroimaging Binding konkurrencedygtig matematisk modellering (systemanalyse) Neurotransmission forbigående dopamin frigivelse PET modellering lineære tidsinvariant rygning F-test ventral-striatum kliniske teknikker
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