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Improved Method for the Preparation of a Human Cell-based, Contact Model of the Blood-Brain Barrier
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Capitoli
- 00:05Titolo
- 01:54In vitro Human BBB Culture Model
- 05:04Experimentation with the Human BBB Model
- 05:54Results: A Human Contact Blood-brain Barrier Model
- 08:08Conclusion
Establishment of human models of the blood-brain barrier (BBB) can benefit research into brain conditions associated with BBB failure. We describe here an improved technique for preparation of a contact BBB model, which permits coculturing of human astrocytes and brain endothelial cells on the opposite sides of a porous membrane.
